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The article presents a case study of a 42-year-old woman with an ulcer covered by a black crust and surrounding palpable tender nodules on the right temple. Her face swelled and an ulcer was developed on her right temple after she received intralesional injections conducted by the unlicensed practitioner. A skin biopsy has been performed to a patient and found out a scopulariopsis infection. It mentions several treatments to the infection including itraconazole and terbinafine.

Toxic epidermal necrolysis (TEN) is a rare, life‐threatening, drug‐induced cutaneous reaction. We herein report our experience regarding causes, clinical course, treatment and sequelae of TEN in Korean patients. In addition, we used the SCORTEN, a severity‐of‐illness score for TEN, to compare the predicted and actual mortality rates, and to evaluate the efficacy of treatment modalities. A retrospective study of 38 patients with TEN during a 13‐year period (1990–2003) at the Asan Medical Center was performed. The mean involved body surface area was 49±17%. All except three cases were associated with medications, most commonly antibiotics, followed by non‐steroidal anti‐inflammatory drugs, acetaminophen and herbal remedies. Fourteen patients had a history of current infection, including upper respiratory infection, pneumonia and herpes simplex infection. The mean time from initial drug administration to the onset of TEN was 9.8±5.7 days. Twenty‐one patients were treated with systemic corticosteroids. Fourteen received high dose intravenous immunoglobulin therapy. The actual mortality rate was 23.7% (9/38), not significantly different from the SCORTEN‐predicted rate (25.5%, 9.699/38). Also based on SCORTEN, treatment with high dose intravenous immunoglobulin showed a trend to lower actual mortality than predicted mortality (standardized mortality ratio (SMR) = 0.425; 95% CI, 0.011–2.368), whereas corticosteroid therapy showed no such difference (SMR = 1.004; 95% CI, 0.369–2.187). [ABSTRACT FROM AUTHOR]

Eosinophilic pustular folliculitis is characterized by an eosinophil-rich inflammatory follicular and perifollicular infiltrate primarily centred at the level of the follicular isthmus and sebaceous duct. Follicular mucinosis has been observed in lesions of eosinophilic pustular folliculitis. Clinical and histological features of eosinophilic pustular folliculitis with follicular mucinosis and alopecia mucinosa are very similar. Alopecia mucinosa may be a clonal T-cell dermatosis. A monoclonal re-arrangement of the T-cell receptor gene was detected in about half of the cases in alopecia mucinosa. To investigate T-cell clonality in a series of eosinophilic pustular folliculitis with follicular mucinosis, we performed heteroduplex analysis of re-arranged T-cell receptor γ gene in seven cases of eosinophilic pustular folliculitis with follicular mucinosis. All cases were negative for heteroduplex-PCR analysis. The failure to demonstrate clonality may be consistent with a reactive nature of eosinophilic pustular folliculitis with follicular mucinosis. [ABSTRACT FROM AUTHOR]

The article discusses the impact of the cutaneous mycobacterium chelonae infection to people. It states that cutaneous M. chelonae infections may develop in immunocompetent patients without trauma history. It infers that the disease can treated with clarithromycin because it showed the lowest minimum inhibitory concentration (MIC) of several drugs tested.

The article presents a case study for a 26-year-old woman having a history of recurrent painful erythematous nodules and swelling on both legs, and myalgia of the calves. A diagnose of autoimmune hepatitis (AIH) was made for her in 2004. Haemoglobin 11.2 g/dl and erythrocyte sedimentation rate 91 mm/h were among the abnormal results that several laboratories found. A diagnose of cutaneous polyarteritis nodosa (CPAN) was made based on the latest findings done to her.

A letter to the editor is presented which discusses a medical case study of a 46-year-old woman who has an anetoderma which is associated with schwannoma.

Presents a case study on cutaneous pseudolymphoma associated with silicone injection in the U.S. Occurence of lymphomas in the vicinity of silicone foreign granulomas; Reference to the case of a male patient who had erythematous and palpable indurations on facial areas; Diagnosis and treatment.