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Cutaneous leishmaniasis (CL) is an infection caused by protozoa from the genus Leishmania. The disease is transmitted by sandflies. Reservoirs are dogs, mice, wild rodents and, more rarely, humans. CL is clinically characterized by a single, polymorphous lesion, usually localized on the face or limbs. Nowadays, CL is more frequently seen among travellers returning from tropical and subtropical countries (1). Cutaneous lymphoid hyperplasia (CLH), also known as pseudolymphoma, is a reactive proliferation, probably secondary to persistent antigenic stimulation. We present here a case of CLH associated with L. panamensis infection.

Sir, In the treatment of cutaneous T-cell lymphomas, radiotherapy plays a well-known role in the management of mycosis fungoides (MF) and Sezary syndrome, as localized radiotherapy or total skin electron-beam irradiation. Furthermore, radiotherapy has been indicated as first choice treatment in large cell CD30+ lymphomas (LCCD30+L) (1, 2), and in pleomorphic small/medium-sized cells lymphomas (PSMSL) (1, 3, 4). The former is characterized by a single nodularulcerative lesion or grouped nodules, rarely multifocal, sometimes spontaneously regressing, showing histopathologically a diffuse non-epidermotropic infiltrate of large cells expressing CD30 phenotype. The latter is defined by the occurrence of one or several dark red nodules, due to a neoplastic infiltrate of pleomorphic small/medium-sized cells, without clinical evidence of concurrent patches typical for mycosis fungoides. In this short report we update our data on the radiological treatment of LCCD30+L (5), evaluate the results of radiotherapy in the treatment of PSMSL, and compare our findings with those reported in the literature (1–4, 6).