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Videocapillaroscopy can be used to assess cutaneous microcirculation modifications in vivo, and therefore allows assessment of variations in the microvascular architecture in psoriatic subjects during treatment. The aim of this study was to observe and quantify the modifications of the superficial capillary bed in psoriatic plaques during treatment with cyclosporin A. Twelve patients with psoriasis vulgaris were treated with an initial dose of 4 mg/kg/day cyclosporin A over a period of 3 months with periodic clinical and capillaroscopic assessments. Clinical resolution of the lesions and a reduction in microcirculatory alterations was observed in 70% of patients, although none returned to a normal capillaroscopic pattern. [ABSTRACT FROM AUTHOR]

Presents case report of a 44-year-old woman who was treated with cyclosporin A for ulcerated necrobiosis lipoidica (NL). Correlation of NL with diabetes; Characteristics of NL; Findings of haematochemical tests; Reasons behind difficulty in the treatment of NL.

The article presents case studies involving livedoid vasculopathy (LV) which refers for skin disease that occurs on calves, dorsum, and ankles. It states the link of the disease with hyperhomocysteinaemia, vitamins, and folic acid supplementation. Also mentioned the the procoagulant state of the LV triggered by vasculopathy, plasminogen, and prothrombin gene mutation.

A letter to the editor is presented about a case of a 20-year-old patient with borrelia infection and pityriasis rosea (PR).