1. Contact Allergy to Oxidized Linalool and Oxidized Limonene is Overrepresented in Individuals with Photocontact Allergy to Ketoprofen.
- Author
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BRUZE, Magnus, MARMGREN, Victoria, ANTELMI, Annarita, HINDSÉN STENSTRÖM, Monica, SVEDMAN, Cecilia, ZIMERSSON, Erik, and MOWITZ, Martin
- Subjects
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LIMONENE , *LINALOOL , *NONSTEROIDAL anti-inflammatory agents , *ALLERGIES , *FISHER exact test - Abstract
Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photoallergic individuals were investigated in comparison with the corresponding rates in individuals without photocontact allergy to ketoprofen, using Fisher's exact test. A total of 4,021 patients were routinely tested with oxidized linalool; of whom 190 (4.7%) tested positively. For oxidized limonene the numbers were 3,797 patients and 111 positive reactions (2.9%). A total of 19 contact allergic reactions to oxidized linalool were noted in 29 patients (65.5%) who also had photocontact allergy to ketoprofen (p < 0.0001). The corresponding figures for oxidized limonene were 10 positive reactions in 24 ketoprofen-photoallergic individuals (41.7%) (p < 0.0001). Contact allergy to oxidized linalool and/or oxidized limonene is common in routinely tested patients with dermatitis and, particularly, in those patients who are photoallergic to ketoprofen. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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