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2 results on '"Romanov AA"'

1. [Microdialysis--a new method of monitoring of the transplanted cadaveric kidneys function].

Author

Khubutia MSh, Zhuravel SV, Kozlov IA, Romanov AA, and Goncharova II

Subjects
Allografts metabolism, Cadaver, Dialysis Solutions chemistry, Female, Glucose analysis, Humans, Kidney metabolism, Lactic Acid analysis, Male, Middle Aged, Pilot Projects, Primary Graft Dysfunction metabolism, Prospective Studies, Pyruvic Acid analysis, Allografts blood supply, Kidney blood supply, Kidney Transplantation, Microdialysis, Monitoring, Physiologic methods, Primary Graft Dysfunction diagnosis
Abstract

Purpose: To assess ischemia-reperfusion injury of renal allograft by microdialysis., Design: A pilot, single-center; prospective study., Patients and Methods: The study included 7 patients (4 males and 3 females, average age was 46.71 ± 6.53 years) after cadaveric kidney allograft transplantation (CKA) under general combined anaesthesia., Conclusions: Microdialysis provides an opportunity of continuous monitoring of metabolic changes in the tissue of transplanted kidney. The main advantage of the monitoring by microdialysis is an opportunity of early identifying of ischemia-reperfusion complications. Thus, early assessment of CKA by microdialysis can be for the improving of patient's treatment in the early post operative period. Further clinical studies must be done to define the role of microdialysis.

Published
2015

2. [Alveolar opening maneuver (mobilization) in intraoperative pulmonary oxygenizing dysfunction in cardiosurgical patients].

Author

Kozlov IA and Romanov AA

Subjects
Adult, Aged, Female, Humans, Intraoperative Complications etiology, Male, Middle Aged, Oxygen blood, Pulmonary Circulation, Pulmonary Gas Exchange, Respiratory Insufficiency etiology, Cardiopulmonary Bypass, Intraoperative Complications therapy, Pulmonary Alveoli, Respiration, Artificial adverse effects, Respiratory Insufficiency therapy, Respiratory Therapy methods
Abstract

The purpose of the study was to investigate arterial oxygenation and hemodynamics during and after alveolar mobilization in the early post-cardiopulmonary bypass (CPB) period of cardiac surgery. The study involved 21 patients aged 30 to 73 years, who had a PaO2/FiO2 below 300 mm Hg in the early post-CPB period. PaO2/FiO2 was less than 200 mm Hg in 4 patients. Alveolar mobilization was performed by means of the "Open lung tool" function of a Servo-i respirator ("Maquet'). PaO2/FiO2 significantly increased (P < 0.5) from 244+/-11 to 472+/-20 mm Hg and thoracopulmonary compliance (Cdyn) increased from 53.3+/-3 to 67.5+/-2.9 ml/cm H20 (p < 0.5). Intrapulmonary shunt (Qs/Qt) significantly decreased from 14+/-1 to 10+/-1.5% (p < 0.5). The mean values of PaO2/FiO2 Cdyn and Qs/Qt were stable at the end of procedures. PaO/FiO, was greater than 350 mm Hg in 62% of the patients. Cardiac index considerably decreased from 2.7+/-0.1 to 225+/-0.1 l/min/m(2) at the peak of alveolar mobilization (p < 0.05); right atrial pressure and mean pulmonary artery pressure were moderately, but significantly higher at that moment. Hemodynamic parameters returned to the baseline levels after alveolar mobilization. There were no significant hemodynamic complications. It is concluded that alveolar mobilization is an effective technique in improving arterial oxygenation and lung biomechanics in cardiosurgical patients under anesthesia.

Published
2007

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