10 results on '"S, Jayanthi"'
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2. Comparison and ranking of superelasticity of different austenite active nickel-titanium orthodontic archwires using mechanical tensile testing and correlating with its electrical resistivity
- Author
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M Vijjaykanth, M S Jayanthi, D Nagarajan, K Usha, and Balashanmugam Baskaranarayanan
- Subjects
Austenite ,lcsh:QD71-142 ,Materials science ,lcsh:Analytical chemistry ,mechanical tensile testing ,lcsh:RS1-441 ,Bioengineering ,General Biochemistry, Genetics and Molecular Biology ,lcsh:Pharmacy and materia medica ,Stress (mechanics) ,ranking ,Ranking ,Nickel titanium ,Electrical resistivity and conductivity ,Ultimate tensile strength ,Pseudoelasticity ,nickel-titanium orthodontic wires ,Original Research Article ,General Pharmacology, Toxicology and Pharmaceutics ,Composite material ,Electrical resistivity tests ,Tensile testing - Abstract
Introduction: The application of light and continuous forces for optimum physiological response and the least damage to the tooth supporting structures should be the primary aim of an orthodontist. Nickel-titanium (NiTi) alloys with their desirable properties are one of the natural choices of the clinicians. Aim: This study was aimed to compare and rank them based on its tensile strength and electrical resistivity. Materials and Methods: The sample consisted of eight groups of 0.017 inch × 0.025 inch rectangular archwires from eight different manufacturers, and five samples from each group for tensile testing and nine samples for electrical resistivity tests were used. Data for stress at 10% strain and the initial slope were statistically analyzed with an analysis of variance and Scheffe tests with P < 0.05. The stress/strain plots of each product were ranked for superelastic behavior. The rankings of the wires tested were based primarily on the unloading curve's slope which is indicative of the magnitude of the deactivation force and secondarily on the length of the horizontal segment which is indicative of continuous forces during deactivation. For calculating the electric resistivity, the change in resistance after inducing strain in the wires was taken into account for the calculation of degree of martensite transformation and for ranking. Results: In tensile testing Ortho Organizers wires ranked first and GAC Lowland NiTi wires ranked last. For resistivity tests Ormco A wires were found superior and Morelli remained last. Conclusion: these rankings should be correlated clinically and need further studies.
- Published
- 2016
3. Antihyperglycemic effect of Coscinium fenestratum and Catharanthus roseus in alloxan-induced diabetic rats
- Author
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Shanmugam Manoharan, S Umadevi, S Jayanthi, and Nagarethinam Baskaran
- Subjects
medicine.medical_specialty ,endocrine system diseases ,medicine.medical_treatment ,Glibenclamide ,chemistry.chemical_compound ,Internal medicine ,Diabetes mellitus ,Alloxan ,medicine ,Pharmacology (medical) ,Medicinal plants ,Coscinium fenestratum ,Nutrition and Dietetics ,biology ,Traditional medicine ,Glycogen ,business.industry ,Insulin ,Catharanthus roseus ,biology.organism_classification ,medicine.disease ,Endocrinology ,chemistry ,Neurology (clinical) ,business ,medicine.drug - Abstract
Introduction : Diabetes mellitus, the life-threatening endocrine disorder, affects 170 million people worldwide every year. Statistical projections about India suggest that 57 million Indians will be affected by diabetes mellitus by the year 2025, making the country with highest number of diabetics in the world. Alloxan-induced diabetes mellitus in experimental animals is commonly used to evaluate the antidiabetic effect of medicinal plants and their constituents. The present study has investigated the antidiabetic efficacy of ethanolic extract of Coscinium fenestratum stem and Catharanthus roseus leaves in alloxan-induced diabetic rats. Materials and Methods: Diabetes mellitus was induced in overnight fasted (>8 hours) Wistar rats by single intraperitoneal injection of freshly prepared alloxan monohydrate (150 mg/kg bw) solution in physiological saline. The mechanistic pathway for the antidiabetic potential of these plants was evaluated by analyzing the status of glucose, insulin, C-peptide, glycosylated hemoglobin, activities of carbohydrate-metabolizing enzymes, and glycogen content. The antidiabetic effect of these plant products was also compared with the standard reference drug, glibenclamide. Results: The study revealed that the ethanolic extract of C. fenestratum stem and C. roseus leaves have potent antidiabetic efficacy in alloxan-induced diabetic rats. The antidiabetic efficacy was also much comparable with that of glibenclamide. Conclusions: The present study concludes that the ethanolic extract of C. fenestratum stem and C. roseus leaves have potent antihyperglycemic effect in alloxan-induced diabetic rats. C. fenestratum and C. roseus could therefore be used as an alternative remedy for diabetes mellitus and its complications.
- Published
- 2011
4. Chronic epidural intracranial actinomycosis: A rare case
- Author
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S Jayanthi, Sunil K Narayan, and A Swaroop
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Diplopia ,medicine.medical_specialty ,business.industry ,medicine.disease ,Surgery ,Images in Neurology ,Skull ,Hematoma ,medicine.anatomical_structure ,Midline shift ,Eosinophilic granuloma ,Granuloma ,Cranial vault ,medicine ,Actinomycosis ,Neurology (clinical) ,medicine.symptom ,business - Abstract
A 13-year-old boy presented with a healing ulcer over the vertex, a healed ulcer above the right eye [Figure 1A], occasional fever, weight loss, diplopia, bilateral proptosis, lagophthalmos and bilateral mild facial palsy. In hospital, he developed left -sided focal seizures and symptoms and signs of raised intracranial pressure. The skull radiograph showed a thickened frontal vault, suggestive of chronic osteomyelitis [Figure 1B]. CT brain conÞ rmed thickening of the skull vault over the right frontal region and revealed an epidural mass in the prefrontal region that was predominantly on the right side but crossed the midline and caused a mass eff ect, with midline shift to the left . Also present was massive white-matt er edema, with eff acement of the ipsilateral ventricle and enlargement of the contralateral one [Figure 1C]. A biopsy from the scalp lesion demonstrated granulation tissue, hematoxyphilic colonies, and gram positive Þ lamentous rods, features that were diagnostic of actinomycosis [Figure 1D]. The boy recovered well withintravenous administration of crystalline penicillin and co-trimoxazole along with oral erythromycin for six weeks, followed by oral co-trimoxazole and erythromycin for six moths. The epidural mass and skull thickening, however, persisted. Clinical features of chronic epidural lesions of the skull and spine can be subtle and treacherous. Signs, rather than the symptoms, of raised intracranial pressure oft en dominate. Spinal lesions may present earlier. Epidural mass lesions can be due to a variety of causes; these include (1) hematoma due to trauma, bleeding diathesis or venous sinus thrombosis; (2) malignant deposits from lymphoma, leukemia, multiple myeloma or chloroma; (3) chronic noninfectious granuloma due to sarcoidosis, eosinophilic granuloma, cholesteatoma, hypertrophic pachymeningitis, Wegener granulomatosis or cranial fascitis; (4) chronic infectious lesions, e.g., aspergillosis or tuberculosis (5); primary neoplasms like chondromas
- Published
- 2009
5. Rare Causes of Hypertrophic Spinal Pachymeningitis Primarily Identified on Spinal MRI.
- Author
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Nedunchelian M, Bhari PT, Shetty AP, Rajasekaran S, and Kamashi SJ
- Abstract
Competing Interests: There are no conflicts of interest.
- Published
- 2022
- Full Text
- View/download PDF
6. Fungal peritonitis in continuous ambulatory peritoneal dialysis: The impact of antifungal prophylaxis on patient and technique outcomes.
- Author
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Kumar KV, Mallikarjuna HM, Gokulnath, and Jayanthi S
- Abstract
Fungal peritonitis (FP) is a rare, but serious complication of peritoneal dialysis. We analyzed the incidence of FP, associated risk factors and outcome of patients with FP and evaluated the role of prophylactic antifungal agent in reducing its incidence. We studied all patients with FP from January 2005 to January 2012. Study period was divided into two parts, period I (January 2005 to January 2010), when prophylactic antifungal was not used and period II (January 2010 to January 2012), when prophylactic antifungal (fluconazole) was used. A total of 142 episodes of peritonitis were documented during this period of which 20 (14%) were FP. During the study period I, 18 of 102 episodes of peritonitis (17.6%) and in the study period II (with antifungal prophylaxis), only 2 of 40 episodes of peritonitis (5%) were due to fungal infection (P = 0.04). Nine out of 20 patients (45%) had prior exposure to antibiotics. Fungal isolates were Candida albicans in 65%, non-albicans Candida in 25%, Rhizopus species in 5% and Alternaria in 5% of the patients. While 12 out of 20 patients (60%) recovered completely and were re-initiated on continuous ambulatory peritoneal dialysis (CAPD), 4 of them expired (20%) and 4 others (20%) were shifted to hemodialysis. Use of prophylactic antifungal agent significantly reduced the incidence of FP (P = 0.04). We conclude that - fluconazole when used as a prophylactic agent in the setting of bacterial peritonitis significantly reduces the incidence of subsequent FP in CAPD patients.
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- 2014
- Full Text
- View/download PDF
7. Chronic epidural intracranial actinomycosis: A rare case.
- Author
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Narayan SK, Swaroop A, and Jayanthi S
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- 2009
- Full Text
- View/download PDF
8. Hepatoprotective activity of six polyherbal formulations in paracetamol induced liver toxicity in mice.
- Author
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Girish C, Koner BC, Jayanthi S, Rao KR, Rajesh B, and Pradhan SC
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- Acetaminophen toxicity, Alanine Transaminase metabolism, Alkaline Phosphatase metabolism, Analysis of Variance, Animals, Aspartate Aminotransferases metabolism, Dose-Response Relationship, Drug, Drug Combinations, Materia Medica therapeutic use, Mice, Plant Extracts therapeutic use, Chemical and Drug Induced Liver Injury drug therapy, Liver drug effects, Materia Medica pharmacology, Phytotherapy methods, Plant Extracts pharmacology
- Abstract
Background & Objective: Polyherbal formulations available with a wide range of indications like protective to liver, appetite and growth promoters, gastrointestinal and hepatic regulator, as treatment for hepatic dysfunction, for hepatic regeneration as well as liver stimulant and tonic. Despite the widespread use, there is a lack of scientific evidence on their efficacy and safety. This study was undertaken to evaluate the hepatoprotective activity of six commercially available formulations, namely Liv 52, Livergen, Livokin, Octogen, Stimuliv and Tefroliv in acute liver toxicity in mice model induced by paracetamol (PCM)., Methods: Swiss albino mice of either sex were used, divided in 28 groups with six in each group. The dose of the polyherbal formulations was calculated from human dose (20 ml/day) using a standard conversion table. They were given as pretreatment (2.60 ml/kg/day) for 7 days by oral route twice a day prior to PCM administration. Hepatotoxicity was induced by administering a single oral dose of PCM (500 mg/kg bw) on day 8. The study parameters were conducted on day 9. The biochemical parameters included liver enzyme levels alanine tranaminases (ALT), aspartate transaminases (AST) and alkaline phosphatase (ALP). The pharmacological and pathological parameters were phenobarbitone sleeping time and macroscopic and microscopic changes of liver tissues respectively., Results: PCM toxicity significantly increased ALT, AST and ALP (321.00 +/- 87.93, 273.17 +/- 45.68, 257.50 +/- 17.64 IU/l vs normal control, 33.33 +/- 0.61, 89.33 +/- 9.50, 152.17 +/- 11.40 IU/l respectively, P<0.05), prolonged phenobarbitone induced sleeping time (from 277.50 +/- 8.04 min to 335.83 +/- 7.00 min, P<0.05). When PCM higher dose (1g/kg p.o. single dose) was used, the liver tissue, in macroscopic appearance, showed extensive necrosis associated with haemorrhages. Low dose (500 mg/kg p.o. single dose) showed punctate haemorrhagic necrosis of liver tissue. In the microscopic studies, PCM induced toxicity showed haemorrhages, fatty changes and necrosis. The pretreatment in low doses (2.6 ml/kg/day) with liquid formulations of Liv 52 and Livergen reversed the PCM induced liver toxicity. At higher doses (5.2 ml/ kg/day), all the six herbal formulations conclusively showed marked beneficial effects in the studied pharmacological, biochemical and histological parameters., Interpretation & Conclusion: The present findings demonstrated the efficacy of polyherbal liquid formulations at two dose levels in PCM induced hepatotoxicity in mice. However, it suggests that a dose adjustment may be necessary to optimize the effects in clinical settings.
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- 2009
9. Pseudoglandular pattern of basaloid cells in pilomatrixoma in the needle aspiration cytology: a case report.
- Author
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Siddaraju N, Mishra MM, Roy SK, Bundele MM, and Jayanthi S
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- Adult, Diagnosis, Differential, Histocytochemistry, Humans, Lymphadenitis pathology, Male, Biopsy, Needle, Pilomatrixoma diagnosis, Pilomatrixoma pathology
- Abstract
A varied cytomorphology of pilomatrixoma often results in diagnostic dilemma. Here, we report a case of pilomatrixoma that presented with prominent gland like arrangement of basaloid cells on cytologic smears causing diagnostic problem. Clinical diagnosis in the present case was cervical lymphadenitis and the cytologic smears showed a strikingly varied morphology with few loose clusters of basaloid cells exhibiting pseudoglandular pattern. A possibility of metastatic carcinoma was considered. However, following histopathologic diagnosis of pilomatrixoma, when cytologic smears were reviewed, it was realized that the ghost cells were overlooked as anucleate squames. Our case highlights the importance of careful clinical and cytologic interpretation of pilomatrixoma. Awareness of the cytomorphologic characteristics of ghost cells and their identification in cytologic smears is highly criticalfor an accurate diagnosis. A prominent basaloid cell component of pilomatrixoma with a pseudoglandular pattern, which has not been described earlier, may easily lead to a false positive diagnosis.
- Published
- 2007
10. Clinical spectrum of Glanzmann's thrombasthenia.
- Author
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Badhe BA, Jayanthi S, and Datta T
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- Adolescent, Blood Platelets pathology, Child, Child, Preschool, Female, Hemorrhage, Hemostasis, Humans, Male, Platelet Aggregation, Platelet Glycoprotein GPIIb-IIIa Complex metabolism, Thrombasthenia physiopathology
- Abstract
Glanzmann's thrombasthenia is a well defined inherited disorder of platelet function characterized by qualitative and qualitative defect in cytoadhesive membrane protein, glycoprotein IIb-IIIa (the platelet fibrinogen receptor). From January 1990 to October, 1999, five patients who presented with mucocutaneous bleeding were detected to have Glanzmann's thrombasthenia. Clinical and laboratory spectrum of this rare disorder was studied which revealed heterogeneity of disease with respect to nature and severity of bleeding unpredictable by laboratory findings.
- Published
- 2000
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