192 results on '"S. Shah"'
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2. Lipoid proteinosis: Review of Indian cases
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Jigna S, Shah and Himali A, Shah
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Otorhinolaryngology ,General Dentistry ,Pathology and Forensic Medicine - Abstract
Lipoid proteinosis (LP) is a rare autosomal recessive disorder characterized by the deposition of amorphous hyaline material in the dermis and submucosal connective tissue. To date500 cases of LP have been described and oral manifestations described in a very few reports. Indian cases are much less reported and reviewed. Hence, here review of 51 Indian LP cases along with a case of histologically proven LP in 12-year-old male patient with typical skin, ocular, laryngeal, oral and radiographic features is done. Cases from 1969 to 2021 were collected using keyword LP on google and google scholar and Indian cases were analyzed afterward. Review with case presentation regarding oral manifestations will help the oral physician to diagnose LP in early stage. more...
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- 2022
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Catalog
3. Bone invasion in oral squamous cell carcinoma: Comparative analytic study in orthopantomogram and technetium 99 m bone scan
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Jigna S, Shah, Jaya, Dubey, and Yogesh Kumar, Rathva
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Oncology ,Head and Neck Neoplasms ,Squamous Cell Carcinoma of Head and Neck ,Carcinoma, Squamous Cell ,Humans ,Technetium ,Mouth Neoplasms ,Neoplasm Invasiveness ,Radiology, Nuclear Medicine and imaging ,General Medicine - Abstract
To compare the bone invasion in orthopantomogram (OPG) and technetium 99 m bone scan in oral squamous cell carcinoma (OSCC).Clinically and histopathologically proven 30 cases of OSCC were randomly selected. OPG and Tech 99m bone scan was carried out in all selected patients. The results were analyzed according to age, sex, and site of involvement. OPG findings and bone scanning uptake were also compared according to site, grade, and difference of uptake.Group of patients which showed definite bone invasion in OSCC were positive in radionuclide uptake imaging while another group of patients which showed no changes in OPG had some patients which were positive on radionuclide uptake imaging while few were negative on both OPG and bone scanning.Combination of OPG and Tech 99m bone scan was more accurate in detecting bone invasion in OSCC than OPG and bone scan alone. more...
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- 2022
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4. Adverse drug reaction: Knowledge, attitude and practice amongst paediatric dentists in India: An electronic survey
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Paridhi S Shah, Anshula Deshpande, Seema Bargale, Susmita S Shah, Bhavna H Dave, and Deepika N Chari
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medicine.medical_specialty ,Descriptive statistics ,business.industry ,Questionnaire ,General Medicine ,Preventive Dentistry ,medicine.disease ,Test (assessment) ,Informed consent ,Family medicine ,Pharmacovigilance ,medicine ,General knowledge ,business ,Adverse drug reaction - Abstract
Background: In India, though pharmacovigilance programme had been introduced way back in 2003, still there are very less cases reported regarding adverse drug reaction (ADR), especially by dental professionals. This led to the necessity to find out the knowledge regarding ADR amongst the dentists and the reasons for underreporting. Moreover, as ADRs are more common and severe amongst paediatric population when compared to adults, this electronic survey was carried out to assess the knowledge, attitude and practices amongst the students pursuing masters in paediatric dentistry. Methods: A questionnaire survey was conducted amongst post-graduate students registered with Indian Society of Pedodontics and Preventive Dentistry. A Google Form with covering letter which included specified instruction format, informed consent, covering letter with clear description of the purpose of the study and questions in different categories were mailed. Descriptive statistics were used to analyse responses. The association of knowledge and attitude with respect to position of paediatric dentists was analysed with Chi-square test. Results: The questionnaire was completed by 274 participants. Ninety per cent of participants were aware that ADR can be caused by the drugs available in the market and such drugs can be banned post availability in the market. Only 20% of the participants were aware of PvPI app but 75% participants opted for online reporting of ADR. Nearly 81% of participants believed that ADR should be reported the moment it is observed and this reporting is basically for the safety of the patients. Nearly 90% of participants agreed that dental materials can cause ADR due to either lack of knowledge to identify ADR and the procedure of reporting or the fear of legal issues. Almost only 4% of the participants have ever attended an ADR workshop. Conclusion: The general knowledge of ADR is prevalent amongst the participants, but there is strong evidence of underreporting and lack of reporting system information. more...
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- 2021
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5. An angulated parotid duct sialolith: Radioimaging in diagnosis
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Jaya Dubey, Jigna S Shah, and Mayur Rathod
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medicine.medical_specialty ,business.industry ,Periapical radiography ,Soft tissue ,Parotid duct ,medicine.disease ,stomatognathic diseases ,medicine.anatomical_structure ,stomatognathic system ,Medicine ,Radiology ,Pericoronitis ,business ,Duct (anatomy) - Abstract
Sialolithiasis is one of the most common diseases of salivary glands and major cause for their dysfunction. It is more common in submandibular glands than in the parotid glands. In this report, the diagnosis and treatment of an unusual angulated parotid duct sialolith in a 25-year-old female in left Stensen's duct are presented with recurrent pericoronitis. Role of soft tissue intraoral periapical radiograph and cone beam computerized tomography in diagnosis and determining location and dimensions of sialolith is discussed. more...
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- 2021
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6. Clinico-radiological progression in COVID-19 patients: Study in a tertiary care hospital
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Ruchir Dave, Dharita S Shah, Shivam O Poddar, Akash G Dholakia, Monila N. Patel, and Parita K Trada
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Pediatrics ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Disease progression ,Retrospective cohort study ,General Medicine ,Disease ,Tertiary care hospital ,Lung involvement ,Sample size determination ,Radiological weapon ,medicine ,business - Abstract
Background: Coronavirus disease 19 (COVID-19) caused by a severe acute respiratory syndrome coronavirus-2 belonging to the Coronaviridae family has caused a global pandemic. As it has emerged as a newer disease, there is a lack of information in many aspects of it. Materials and Methods: We tried to study the progression in the COVID-19 patients in terms of their clinical, laboratory, and X-rays as a radiological modality, for that, we did a single-centered retrospective observational study in 159 laboratory-confirmed COVID-19 positive patients with sample size being duration dependent. Results: We found statistically significant correlation between clinical parameters and lung involvement based on chest X-ray (CXR) scoring and also temporal variation as the disease progression occurs. Conclusion: Along with clinical and laboratory parameters, CXRs can be used as a useful bedside, inexpensive, and easily available radiological tool for assessment in resource-poor settings where high-resolution computed tomography scans are not feasible. more...
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- 2021
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7. A case of bilateral lower motor neuron facial palsy in cerebral venous sinus thrombosis
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Vaishal S Shah and Vijay Sardana
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Palsy ,business.industry ,Cranial nerves ,facial paralysis ,cerebral venous thrombosis ,cranial nerve palsy ,General Medicine ,Anatomy ,medicine.disease ,RC31-1245 ,Lower motor neuron ,Facial paralysis ,Venous thrombosis ,medicine.anatomical_structure ,medicine ,Cerebral venous sinus thrombosis ,business ,Internal medicine ,Abducens nerve ,Superior sagittal sinus - Abstract
Cerebral venous thrombosis commonly presents with headache, seizure, and motor weakness. Among cranial nerves, the abducens nerve is common to get involved. We report a patient who had cerebral venous sinus thrombosis involving superior sagittal sinus, right lateral sinus, and right internal jugular vein and presented with bilateral lower motor neuron (LMN) facial palsy besides bilateral abducens nerve palsy and bilateral optic nerve involvement in the form of papilledema. A few cases of cerebral venous thrombosis involving lateral sinus with ipsilateral LMN facial nerve palsy have been reported. Our case highlights the rare occurrence of bilateral LMN facial palsy with unilateral lateral sinus involvement. more...
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- 2021
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8. Resin infiltration technique: A case report and literature review
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Deepika N Chari, Paridhi S Shah, and Bhavna H Dave
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Enamel paint ,business.industry ,fungi ,food and beverages ,Dentistry ,Resin infiltration ,Enamel hypoplasia ,medicine.disease ,stomatognathic diseases ,stomatognathic system ,visual_art ,visual_art.visual_art_medium ,medicine ,business - Abstract
An incomplete/defective formation of organic enamel matrix of teeth leads to enamel hypoplasia. Such spots are prone to caries and provoke plaque accumulation. This can involve color alternation which can be of major esthetic concern. Although complete color making might not be achieved, resin Infiltration CONcept (ICON) has few benefits over other methods of being noninvasive, does not require anesthesia, and the procedure can be performed in a single sitting. This paper along with a case has a brief literature review of ICON (resin infiltration technique). more...
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- 2021
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9. Role of areca nut and smokeless tobacco-related habit in altering physical properties of saliva – A comparative study
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Roseline A Patel, Jigna S Shah, Bhavin B Dudhia, and Purv S Patel
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Medical physics. Medical radiology. Nuclear medicine ,salivary flow rate ,Otorhinolaryngology ,ph ,Dentistry ,digestive, oral, and skin physiology ,R895-920 ,RK1-715 ,Radiology, Nuclear Medicine and imaging ,buffering capacity ,smokeless tobacco habit ,areca nut habit ,General Dentistry - Abstract
Context: Saliva performs multiple functions and is of paramount importance for the maintenance of oral health. Hence, alterations in its physical properties like salivary flow rate, buffering capacity and pH can be deleterious to the oral cavity. Areca nut and smokeless tobacco products are known to alter the mucosa as well as the saliva. Aims and Objectives: The study is aimed to compare the alteration in the salivary properties like stimulated salivary flow rate, pH, and buffering capacity between subjects with areca nut and smokeless tobacco habit and without in subjects without habit. A correlation between the habit frequency, duration, and exposure on the same parameters was also ascertained. Settings and Design: It is a comparative study using purposive sampling, comprising of 100 subjects within age group 18–50 years of any gender. The sample size constituted of 50 subjects (group A) with a habit of areca nut and smokeless tobacco and 50 subjects (group B) without any habit. Salivary properties like salivary flow rate, buffering capacity, and pH were analyzed in both groups to test a hypothesis that the habit results in changes in the salivary properties and that there is a correlation between the changes and the frequency, duration, and exposure of the habit. Materials and Methods: Saliva samples were collected from these subjects for analysis of salivary flow rate (SFR), pH, and buffering capacity using the GC Saliva Check Buffer Kit™. Statistical Analysis Used: Data were analyzed by using the SPSS software program, version 27.0. Results: The mean stimulated salivary flow rate among group A was 3.34 ± 1.32 and pH was 6.50 ± 0.54. The mean stimulated salivary flow rate among group B was 4.42 ± 1.48 and the pH was 7.04 ± 0.47. The difference in these values was found to be statistically significant. Conclusion: Alterations in SFR and salivary pH and buffering capacity are observed in habitual chewers of areca nut alone and areca nut with other products. The alteration is dependent on the type of habit and the habit exposure frequency and duration. more...
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- 2021
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10. Association of preterm low-birth-weight infants and maternal periodontitis during pregnancy: An interventional study
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Bhavna Haresh Dave, Ekta B Shah, Rita V Gaikwad, and Susmita S Shah
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Periodontitis ,medicine.medical_specialty ,Pregnancy ,Obstetrics ,business.industry ,Infant, Newborn ,Pregnancy Outcome ,Context (language use) ,Odds ratio ,Disease ,Infant, Low Birth Weight ,medicine.disease ,Low birth weight ,Statistical significance ,Relative risk ,medicine ,Humans ,Premature Birth ,Female ,Periodontal Index ,medicine.symptom ,business ,General Dentistry - Abstract
Context: The impact of periodontal disease during pregnancy and its effect on adverse pregnancy outcomes is seen in the literature. When it comes to the link of disease related to periodontium to that of adverse pregnancy outcomes, a need can arise if a significant cause-effect relationship does exist or not between them. Aim: The study was aimed to determine the association of periodontal health status in pregnant women with the occurrence of preterm low birth weight (LBW) infants in Vadodara, Gujarat. Settings and Design: An interventional study with 100 patients was conducted, of which 67 participants were included in the control group and 33 participants were included in the intervention group. A total of 12 participants dropped out from the study and 88 were analyzed for the outcome. Subjects and Methods: The Community periodontal Index of Treatment needs index was taken for all enrolled participants and then were divided into interventional group and control group. Participants in the interventional group underwent scaling and root planning. Data related to the time of delivery and weight of the baby was taken from the hospital records. Statistical Analysis: A comparison of baseline characteristics was made using unpaired t-test. Chi-square test was used for the analysis of intergroup comparison. The odds ratio and the relative risk calculation were also done. P ≤ 0.05 was considered for statistical significance. Results: The odds ratio for both preterm and LBW were 3.86 times and 2.96, respectively. The Chi-square statistical test analysis was statistically significant for both preterm and LBW infants on the intergroup comparison. Conclusion: Periodontal disease can be considered as one of the risk factors for preterm LBW babies as not only the presence of disease condition causes an increase in inflammatory mediator but also the elimination of the disease condition reduces the adverse pregnancy outcomes. more...
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- 2021
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11. A cross sectional observational study of pediatric dermatophytosis: Changing clinico mycological patterns in Western India
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Krishna B. Bhalala, Pawan Gupta, Mamta Dhayal, Saurabh Jaiswal, Kapisha S. Shah, Yesha Ruchir Patel, Suby Arora, Shital Poojary, Khanda S Khot, Jimish Bagadia, and Ashish Rai
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medicine.medical_specialty ,biology ,medicine.diagnostic_test ,business.industry ,Incidence (epidemiology) ,Tinea incognito ,medicine.medical_treatment ,child ,trichophyton rubrum ,trichophyton mentagrophytes ,tinea ,steroids ,tinea incognita ,Physical examination ,Dermatology ,Trichophyton rubrum ,biology.organism_classification ,medicine.disease ,Pediatrics ,RJ1-570 ,RL1-803 ,Etiology ,Medicine ,Outpatient clinic ,Trichophyton ,business ,Topical steroid - Abstract
Introduction: The last few years have seen a significant rise in the incidence of dermatophytosis across India. Vulnerability of children to this disease is more than adults due to multiple factors. However, limited data are available regarding clinical and mycological variants of dermatophytosis in children. Materials and Methods: A cross-sectional observational study was designed at the dermatology outpatient department in Mumbai. The aim of the study was to assess the clinical profile and identify the causative fungal species in pediatric dermatophytosis. Sixty-seven children below 14 years of age with a clinical diagnosis of dermatophytosis were included by the simple random sampling method. A detailed history (duration of lesions, topical creams used, similar lesions in contacts, contact with pets, and other comorbidities/comedications) was taken and clinical examination (sites of involvement, number of lesions, associated erythema/scaling, morphology, and extent of lesions) was done followed by fungal mount preparation (potassium hydroxide (KOH) and KOH with Chicago Sky Blue stain) and culture of the scrapings on Sabouraud's agar medium containing chloramphenicol and cycloheximide. Microsoft Excel and SPSS-20 software were used to analyze the data. Results: A total of 42 male and 25 female children (mean age – 6.2 years) were included in the study. Prior topical applications of steroids±antifungal combinations were used in 57 cases (85%) before presenting to the dermatologist. About 76.12% (n = 51) of cases had positive family/contact history. Thirty-five children (52.2 %) had extensive disease. Multiple atypical clinical patterns were observed: tinea incognito, irregular geographic plaque, tinea recidivans, tinea pseudo-imbricata, penile tinea, and annular plaques on scalp. Trichophyton mentagrophytes complex was the most common isolate from cultures grown from scrapings, in 14/19 cases (73.7%). Conclusion: This clinico-mycological study highlights the changing clinical patterns (including Tinea pseudoimbricata, geographically patterned plaques) and shift in the etiological agent in childhood dermatophytosis. The study brings into focus the increasing proportion of T. mentagrophytes, high percentages of topical steroid abuse by parents in children, and positive family/close-contact history in children. more...
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- 2021
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12. Comparison of injection granisetron versus injection ondansetron for control of intraoperative nausea and vomiting and post-operative nausea and vomiting among the women undergoing lower segment caesarean section under spinal anaesthesia
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Pravin C Patel, Dipika Parmar, Rutu S Shah, and Usha Patel
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music.instrument ,Nausea ,business.industry ,medicine.medical_treatment ,Therapeutic effect ,General Medicine ,Granisetron ,Ondansetron ,Anesthesia ,medicine ,Vomiting ,Lower segment caesarean section ,Caesarean section ,medicine.symptom ,business ,music ,Adverse effect ,medicine.drug - Abstract
Background and Objective: The present study was intended to compare the preventive and therapeutic effects of injection granisetron and injection ondansetron on the incidence of intraoperative nausea and vomiting and post-operative nausea and vomiting (IONV and PONV) in patients undergoing lower segment caesarean section under spinal anaesthesia. Materials and Methods: It was a hospital-based single-blind comparative study among 90 women undergoing caesarean section with spinal anaesthesia. One group of 45 women has been given 2 mg granisetron IV, while another group of 45 women was given ondansetron 4 mg IV. IONV, PONV and adverse events among both the groups were studied. Results: IONV was found among 13.33% of persons in ondansetron group, while it was 8.89% among the granisetron group. Early and late PONV was low in the granisetron group as compared to ondansetron group. Headache, drowsiness and constipation were low in the granisetron group as compared to the ondansetron group. Conclusion: Granisetron 2 mg IV is better in preventing intraoperative as well as PONV as compared to ondansetron 4 mg IV. more...
- Published
- 2021
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13. Presurgical assessment of alveolar ridge dimensions before dental implant procedures by OPG&CBCT – A comparative study based on fryback & thornbury model
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Purva B Butala, Purv S Patel, Jigna S Shah, and Bhavin B Dudhia
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lcsh:Medical physics. Medical radiology. Nuclear medicine ,Cone beam computed tomography ,Panoramic radiograph ,lcsh:R895-920 ,Radiography ,medicine.medical_treatment ,cone -beam computed tomography ,stomatognathic system ,dental implants ,Alveolar ridge ,Medicine ,media_common.cataloged_instance ,Radiology, Nuclear Medicine and imaging ,Dental implant ,General Dentistry ,Dental surgeon ,Dental alveolus ,media_common ,Orthodontics ,business.industry ,respiratory system ,lcsh:RK1-715 ,Otorhinolaryngology ,lcsh:Dentistry ,panoramic radiography ,Implant ,business - Abstract
Background and Aims: Replacing missing teeth is one of the most common challenges faced by the dental surgeon. The invention of dental implants has brought about a great change in successfully delivering a fixed prosthesis to the patient. Precise radiographic assessment of available alveolar bone is of prime importance for dental implant placement. Panoramic radiograph provides an overview of the jaw bones and is considered adequate in the initial evaluation of the implant site; however, they do not provide the buccolingual dimension of the implant site. CBCT provides volumetric imaging with the ability to visualize the imaged region in virtually any plane. The objective of this study was to compare panoramic radiography (OPG) with cone-beam computed tomography (CBCT) for pre-surgical implant site evaluation. Materials and Methods: A total of 150 potential implant sites in 94 patients who were subjected to OPG and CBCT imaging previously were selected for the study. The height, width, and length of the available bone were measured for all the implant sites (except bone width which was measured on CBCT alone). Out of these, OPG & CBCT findings of 60 potential implant sites were evaluated by comparison with the surgical gold standard dimensions of actual dental implant placed. A comparison of all the values obtained with the two imaging modalities was done and the data was tabulated for statistical analysis. Results: The mean value of bone height using OPG and CBCT were found to be 12.15 mm and 11.99 mm, respectively. The mean value of the length of the edentulous jaw segment using OPG and CBCT was found to be 8.10 mm and 8.98 mm respectively. The mean value of the width of the crestal bone below the height of the crest using CBCT was found to be 5.46 mm. Conclusion: The overall results suggested that CBCT is better in depicting the bone height and bone width as compared to OPG; however, the length of the edentulous jaw segment is better depicted by OPG as compared to CBCT. more...
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- 2020
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14. Posterior sagittal approach for uterovaginal anastomosis in a case of congenital cervical atresia with anorectal malformation
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Beejal V Sanghvi, Rahul K. Gupta, Satej S Mhaskar, Sandesh V. Parelkar, Pooja Tiwari, Kedar P Mudkhedkar, and Rujuta S Shah
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medicine.medical_specialty ,lcsh:Surgery ,posterior sagittal approach ,030232 urology & nephrology ,Rectum ,Case Report ,Anastomosis ,Cervical agenesis ,03 medical and health sciences ,Standard anatomical position ,0302 clinical medicine ,030225 pediatrics ,medicine ,Hematosalpinx ,Cervical atresia ,Hematometra ,business.industry ,lcsh:RJ1-570 ,lcsh:Pediatrics ,lcsh:RD1-811 ,hematometra ,Anus ,medicine.disease ,hematosalpinx ,Sagittal plane ,Surgery ,medicine.anatomical_structure ,Pediatrics, Perinatology and Child Health ,business - Abstract
Cervical atresia is a rare association with anorectal malformation (ARM) which can be missed till puberty in the presence of normal vaginal orifice. A 12-year-old girl operated for ARM in neonatal age presented with primary amenorrhea. She had a normal vaginal opening, short perineal body, and prolapsed anteposed anus and was diagnosed with cervical agenesis. As the posterior sagittal approach is standard to place the rectum in correct anatomical position, reconstruction of the anus along with adequate perineal body and uterovaginal anastomosis was performed through this approach. This report highlights the utility and versatility of this approach for the management of such complex cases. more...
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- 2020
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15. Sisters with no pain, no tears: A report of a new variant of hereditary sensory and autonomic neuropathy (Type IX) Caused by a novel SCN11A mutation
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Shital Poojary, Kapisha S. Shah, Krishna B. Bhalala, and Saurabh Jaiswal
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insensitivity to pain ,Anhidrosis ,business.industry ,Indian origin ,Case Report ,Dermatology ,lcsh:RL1-803 ,Gene mutation ,New variant ,medicine.disease ,Bioinformatics ,030207 dermatology & venereal diseases ,03 medical and health sciences ,hereditary sensory and autonomic neuropathy Type IX ,0302 clinical medicine ,Mutation (genetic algorithm) ,Hereditary sensory and autonomic neuropathy ,lcsh:Dermatology ,Tears ,Medicine ,medicine.symptom ,business ,Novel mutation ,SCN11A gene - Abstract
Lack of pain sensation in children involves a rare group of heritable disorders; hereditary sensory and autonomic neuropathy (HSAN). Till date, eight types of HSAN have been described depending on the clinical phenotype and the underlying gene mutation. We report a new variant of HSAN (Type IX) in two siblings (of Indian origin) with a novel mutation of SCN11A gene and a distinct clinical phenotype. more...
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- 2020
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16. Fluid administration in critically ill children: Striking a balance!!!!
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Sachin S Shah
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Fluid administration ,medicine.medical_specialty ,Balance (accounting) ,Critically ill ,business.industry ,lcsh:RJ1-570 ,medicine ,lcsh:Pediatrics ,Intensive care medicine ,business - Published
- 2020
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17. Malignant peripheral nerve sheath tumor: A rare malignancy
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Jigna S Shah, Harleen Bali, and Sheetal Sharma
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Pathology ,medicine.medical_specialty ,Schwann cell ,Case Report ,Malignant peripheral nerve sheath tumor ,Malignancy ,Malignant nerve sheath tumor ,Pathology and Forensic Medicine ,03 medical and health sciences ,0302 clinical medicine ,Peripheral nerve ,Medicine ,Neurofibroma ,Neurofibromatosis ,General Dentistry ,neurofibromatosis ,rare malignancy ,business.industry ,medicine.disease ,peripheral nerve origin ,medicine.anatomical_structure ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Immunohistochemistry ,Sarcoma ,business ,030217 neurology & neurosurgery ,S-100 protein - Abstract
Malignant peripheral nerve sheath tumor (MPNST) is also termed as spindle cell malignancy of the peripheral nerve Schwann cell. It is a rare and highly aggressive, soft-tissue sarcoma of ectomesenchymal origin that accounts for 10% of all sarcomas and only 10%–12% of all lesions occur in the head-and-neck region, thus making it a rare entity. It arises de novo or from the preexisting benign neurofibroma. The diagnosis of MPNST is one of the most elusive among the soft-tissue tumors because of its greater variability in overall presentation both clinically and histologically. This difficulty can be overcome by the use of immunohistochemistry. This article presents a rare case of MPNST of the oral cavity in a 40-year-old female patient with a brief review of the current literature. more...
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- 2020
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18. Solitary Plasmacytoma of Dorsal Spine
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Prashant Pradhan, Sanjay Kumar Tripathi, Munjal S Shah, Shaikh Muzammil, Amit Kohli, Ram Chaddha, and Saurav Narayan Nanda
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Dorsum ,Spine (zoology) ,business.industry ,Medicine ,Anatomy ,business ,Solitary plasmacytoma - Published
- 2014
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19. An In-Vitro Evaluation of the Flexural Strength of Heat-Polymerized Poly (Methyl Methacrylate) Denture Resin Reinforced with Fibers
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Dipti S Shah and Komal Ladha
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Materials science ,Glass fiber ,Bending ,Poly(methyl methacrylate) ,Flexural strength ,Polymerization ,visual_art ,visual_art.visual_art_medium ,Original Article ,Fiber ,Oral Surgery ,Composite material ,Reinforcement ,General Dentistry ,Acrylic resin - Abstract
Fracture strength of denture base resins is of great concern and many approaches have been made to improve the fracture resistance of acrylic resin dentures by strengthening them. Purpose of the study was to assess the effect of a Novel pre-impregnated glass fiber reinforcement system and nylon fiber reinforcement on the flexural strength of conventional heat-polymerized poly(methylmethacrylate) [PMMA] denture resin under dry and wet storage conditions. Forty specimens of standard dimensions were prepared for each of the four experimental groups; unreinforced conventional acrylic resin and the same reinforced with unidirectional Stick (S) glass fibers, woven Stick Net (SN) glass fibers and nylon fibers. Each group was further subdivided into two groups of 20 specimens each on the basis of storage conditions (dry and wet). All 160 specimens were then subjected to a 3-point bending test and flexural strength was calculated. Statistical analysis was carried out using student t test and 1-way analysis of variance (ANOVA). Stick and Stick Net glass fiber reinforcements enhanced the flexural strength of conventional heat-cured PMMA denture resin. Specimens reinforced with Stick glass fibers exhibited highest flexural strength followed by those reinforced with Stick Net glass fibers. Nylon fiber reinforcement decreased the flexural strength of acrylic resin. All the specimens in the four groups stored under wet conditions showed decrease in flexural strength in comparison to those stored in dry conditions. The reinforcement of denture base resin with pre-impregnated glass fibers may be a useful means of strengthening denture bases. Use of nylon as a reinforcement fiber is not desirable as it decreased the flexural strength of acrylic resin. more...
- Published
- 2011
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20. Constraints among patients while opting dental implant as a treatment option
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Ankur Desai, Sanket S Shah, Harshal Champaneri, Manish Sinha, Siddharth Desai, and Manisha Agarwal
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education.field_of_study ,business.industry ,Missing tooth ,medicine.medical_treatment ,Population ,Treatment options ,Dentistry ,Dental patients ,stomatognathic diseases ,stomatognathic system ,Research centre ,Medicine ,Outpatient clinic ,Implant ,business ,education ,Dental implant - Abstract
Aim: To assess the constraints among patients while opting dental implant as a treatment option among the randomly selected sample of dental patients attending the outpatient department (OPD) of Vaidik Dental College and Research Centre, Daman, India. Materials and Methods: Information on demographic characteristics, knowledge about implant as an option for missing tooth replacement, source of information, and knowledge about other options of tooth replacement were obtained from patients visiting various dental OPDs of hospital and private dental clinics using nationwide self-explanatory survey. Results: Among the 1000 responses retrieved, 27% of the respondents felt moderately well informed about the dental implant treatment. Only 9% of the respondents had dental implant treatment before and 17% felt well informed about the different alternatives of replacing missing teeth. Dentists were the main source of information regarding dental implant treatment modality followed by friends and electronic media. A total of 55.6% of the respondents felt implant to be as good as own teeth in function, whereas high cost was the major limiting factor for implant treatment. Conclusion: A total of 56% of Daman population were aware of dental implant as an alternative for replacing missing teeth. Necessary efforts and measures should be made to raise the awareness of dental implant treatment in the country. more...
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- 2019
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21. Antiepileptic drug-induced Stevens–Johnson syndrome: Which one to stop or continue?
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Falguni Ankur Chaudhari, Jignesh Vaishnani, Dipsa Digant Shastri, and Parag S. Shah
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medicine.medical_specialty ,lcsh:RC435-571 ,business.industry ,lcsh:Psychiatry ,medicine ,Antiepileptic drug ,Stevens johnson ,General Medicine ,business ,Dermatology - Published
- 2019
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22. A study on psychiatric disorders, body image disturbances, and self-esteem in patients of Cushing's disease
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Akanksha Sharma, Neena Sawant, and Nalini S. Shah
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psychiatric morbidity ,medicine.medical_specialty ,Psychosis ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Disease ,Body image disturbances ,behavioral disciplines and activities ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,medicine ,Psychiatry ,Depression (differential diagnoses) ,self-esteem ,business.industry ,Beck Depression Inventory ,Cushing's disease ,medicine.disease ,humanities ,Major depressive disorder ,Original Article ,medicine.symptom ,business ,Mania ,030217 neurology & neurosurgery ,Psychopathology - Abstract
Background: Cushing's disease (CD) is a rare endocrine disorder associated with increased serum levels of cortisol secreted due to an underlying tumour in pituitary. Psychiatric disturbances like depression, psychosis, mania along with body image disturbances are seen in patients of CD. Hence, we undertook this research to find the prevalence and type of psychiatric disorders, body image disturbances, and self-esteem in patients of CD. Materials and Methods: Thirty-five patients diagnosed as CD as per the standard criteria by the endocrinologist were recruited after informed consent and ethics approval. Proforma with demographic details, Structured Clinical Interview for DSM-IV, Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale, and Body Image Concern Inventory were used for assessment of the aims. Results: 65% patients had psychopathology with 21% patients having major depressive disorder, 62% patients had mild, and 28% had moderate depression on BDI. 50% patients had body image disturbances and 60% had low self-esteem. Depression was found to have a negative correlation with self-esteem and positive correlation with body image disturbances. Conclusion: A high prevalence of psychopathology is seen in patients of CD which may often go undetected. Liaison with the endocrinologist would also work towards improving the issues of body image disturbances and self-esteem for better prognosis for the patient. more...
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- 2018
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23. Peripheral ossifying fibroma: An unusual presentation
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Jigna S Shah and Sheetal Sharma
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Pathology ,medicine.medical_specialty ,endocrine system diseases ,business.industry ,Central ossifying fibroma ,Soft tissue ,Peripheral ossifying fibroma ,Connective tissue ,Histology ,medicine.disease ,medicine.anatomical_structure ,medicine ,Differential diagnosis ,Presentation (obstetrics) ,business ,Calcification - Abstract
Peripheral ossifying fibroma (POF) is a focal, reactive, non-neoplastic tumor-like growth of the soft tissue occurring frequently in the maxillary anterior region, mainly affects females, predominating in the second decade of life. POF typically presented as a solitary, slow growing nodular mass that is either pedunculated or sessile. POF is commonly associated with poor oral hygiene, trauma, microorganisms etc and majority of cases showing no marked underlying bone involvement radiographically. The definitive diagnosis is based on histology, with identification of cellular connective tissue and focal presence of osseous component or other calcifications. Surgery is the treatment of choice, though it has a recurrence rate of 8-20%. We report an unusual case of a large POF in the posterior mandible region of a male child patient with histopathological correlations and also highlights the differential diagnosis and management. more...
- Published
- 2018
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24. Aggressive angiomyxoma of maxilla: A confounding clinical condition with rare occurrence!
- Author
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Jigna S Shah, Mahalaxmi Panda, and Sheetal Sharma
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Aggressive angiomyxoma ,medicine.medical_specialty ,business.industry ,Confounding ,Case Report ,030206 dentistry ,medicine.disease ,prominent vasculature ,Pathology and Forensic Medicine ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Otorhinolaryngology ,Maxilla ,abundant myxoid matrix ,Medicine ,Surgical excision ,Radiology ,business ,Head and neck ,Angiomyxoma ,General Dentistry ,Alveolar mucosa - Abstract
The angiomyxomas are rarely reported in the head and neck region; this paper entails a case of aggressive angiomyxoma presenting as a growth in the maxillary anterior alveolar mucosa and lip region for 1 year, which was accurately identified and treated successfully by surgical excision. An attempt has been made to highlight the clinical and pathologic stand out features of this tumor with intricate emphasis, alongside a literary review. more...
- Published
- 2018
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25. Sclerotherapy in pyogenic granuloma and mucocele
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Ashish F Ranghani and Jigna S Shah
- Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine ,medicine.medical_specialty ,lcsh:R895-920 ,medicine.medical_treatment ,Mucocele ,pyogenic granuloma ,02 engineering and technology ,polidocanol ,Insulin syringe ,Polidocanol ,Lesion ,Oral pyogenic granuloma ,Blood loss ,sclerotherapy ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Sclerotherapy ,Radiology, Nuclear Medicine and imaging ,General Dentistry ,business.industry ,Pyogenic granuloma ,020208 electrical & electronic engineering ,medicine.disease ,Surgery ,lcsh:RK1-715 ,Otorhinolaryngology ,lcsh:Dentistry ,medicine.symptom ,business ,medicine.drug - Abstract
Aim and Objective: To evaluate the effect of intralesional injection of polidocanol for treating pyogenic granuloma and mucocele that commonly in the oral cavity. This study also aimed to analyze the effect of polidocanol in both lesions of various sizes. Materials and Methods: Fifteen clinically diagnosed cases of oral pyogenic granuloma (8 cases) and mucocele (7 Cases) were included in the study. After topical anesthesia application, 0.5–1 ml of polidocanol was injected using an insulin syringe into the lesion till the solution leaked out. Each patient was recalled after 1 week and evaluated; if the lesion did not resolve, second and third injections were given consecutively. Results: All 15 patients showed complete regression of the lesion after 1–3 consecutive injections in a weekly interval. Recurrence of one case of mucocele occurred. Conclusion: Sclerotherapy is simple, minimally invasive, economical, and of minimal discomfort to the patient; there is negligible blood loss, and less surgical expertise is required. Size of the lesion determines the number of weekly injections of sclerotherapy required for complete resolution of the lesion; however, numbers of injections do not depend on age, sex, and site of the lesion. more...
- Published
- 2018
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26. Comparing the Effect of a Resin Based Sealer on Crown Retention for Three Types of Cements: An In Vitro Study
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Mansukh Thummar, Pankaj Patel, Dipti S Shah, and Varun Pitti
- Subjects
Cement ,Materials science ,business.industry ,medicine.medical_treatment ,technology, industry, and agriculture ,Glass ionomer cement ,Dentistry ,Tooth surface ,Zinc phosphate ,Cementation (geology) ,Crown (dentistry) ,chemistry.chemical_compound ,stomatognathic system ,chemistry ,medicine ,Original Article ,Adhesive ,Oral Surgery ,Composite material ,business ,General Dentistry ,Zinc Phosphate Cement - Abstract
To determine the effect of resin based sealer on retention of casting cemented with three different luting agents. 55 extracted molar teeth were prepared with a flat occlusal surface, 20° taper and 4 mm axial height. The axial surface of each specimen was determined. The specimen were then distributed into five groups based on decreasing surface area, so each cementation group contained 11 specimens with similar mean axial surface area. A two-step, single bottle universal adhesive system (One-Step-Resinomer, Bisco) was used to seal dentin after the tooth preparation. Sealer was not used on the control specimens except for the modified-resin cement (Resinomer, Bisco) specimens that required use of adhesive with cementation. Using ceramometal (Wirobond(®), BEGO), a casting was produced for each specimen and cemented with either zinc phosphate (Harvard), glass ionomer (Vivaglass) or modified resin cement (Resinomer) with single bottle adhesive. All the castings were cemented with a force of 20 kg. Castings were thermal cycled at 5 and 55 °C for 2,500 cycles and were then removed along the path of insertion using a universal testing machine at 0.5 mm/min. A single-factor ANOVA was used with a = 0.05. The nature of failure was also recorded. The mean stress removal for non sealed zinc phosphate, sealed zinc phosphate, non sealed glass ionomer, sealed glass ionomer and modified resin cement was found to be 3.56, 1.92, 2.40, 4.26, 6.95 MPa respectively. Zinc phosphate cement remained principally on the castings when the tooth surface was treated with the sealer and was found on both the tooth and the casting when the sealer was not used. Fracture of root before dislodgement was seen in 9 of 11 specimens with modified resin cement. Resin sealer decreases the retention of the castings when used with zinc phosphate and increases it when used with glass ionomer cement. The highest mean dislodgement force was measured with modified resin cement. more...
- Published
- 2013
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27. Primary Sjogren's syndrome presenting as hypokalemic paralysis: A case series
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T Jamale, M Goroshi, Shruti Khare, and Nalini S. Shah
- Subjects
Exocrine gland ,Pathology ,medicine.medical_specialty ,Pediatrics ,Anti-Ro/La ,030232 urology & nephrology ,potassium citrate ,lcsh:Medicine ,Signs and symptoms ,Hypokalemic paralysis ,Renal tubular acidosis ,03 medical and health sciences ,0302 clinical medicine ,Renal tubular dysfunction ,Sjögren's International Collaborative Clinical Alliance 2012 ,medicine ,Case Series ,030203 arthritis & rheumatology ,business.industry ,lcsh:R ,Mean age ,General Medicine ,medicine.disease ,Hypokalemia ,stomatognathic diseases ,medicine.anatomical_structure ,renal tubular acidosis ,medicine.symptom ,Sjogren s ,business - Abstract
Primary Sjögren's syndrome (pSS) primarily involves exocrine glands, and renal tubular acidosis (RTA) is seen in one-third of the cases. RTA with hypokalemic paralysis as a presenting feature of pSS is described in few case reports in literature. We report 13 cases who presented as hypokalemic paralysis, and on evaluation were diagnosed to be pSS, as per the diagnostic criteria laid by the Sjögren's International Collaborative Clinical Alliance (2012). All patients were female, with a mean age at presentation being 33.1 ± 8.22 years (range, 25–48 years). Eleven patients had a complete distal RTA and two patients had incomplete distal RTA at the time of presentation. 62% (8/13) of patients had no signs and symptoms of exocrine gland involvement. All the cases were managed with oral alkali therapy, and six patients received additional immunomodulating agents. No improvement in renal tubular dysfunction (in the form of a reduction in the alkali dose) after immunomodulating therapy was observed over a mean follow-up of 2.8 years. Renal tubular dysfunction can be the presenting manifestation of pSS. It is important to consider the possible presence of this disorder in adults with otherwise unexplained distal RTA or hypokalemia. more...
- Published
- 2017
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28. Clinical applications of ultrasonography in diagnosing head and neck swellings
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Vijay K Asrani and Jigna S Shah
- Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine ,medicine.medical_specialty ,lcsh:R895-920 ,030218 nuclear medicine & medical imaging ,Benign tumor ,swelling ,03 medical and health sciences ,0302 clinical medicine ,Vascularity ,medicine ,Head and neck ,Benign neoplasms ,business.industry ,Ultrasound ,Soft tissue ,ultrasonography ,030206 dentistry ,medicine.disease ,Predictive value ,lcsh:RK1-715 ,lcsh:Dentistry ,Color Doppler ,Radiology ,medicine.symptom ,Ultrasonography ,business - Abstract
Background: Ultrasonography is well-known for its application in medicine, and has been recently gaining importance for its use in the orofacial region. Aims and Objective: The present study aims to determine the efficacy of ultrasonography in diagnosing soft tissue swellings of the head and neck. Materials and Methods: Thirty patients with the head and neck soft tissue swelling were included in the study and all were subjected to ultrasonography. Various findings were recorded such as shape, boundary, echo-intensity, ultrasound architecture, presence of necrosis, posterior echoes, ultrasound characteristic of lesion, and vascularity, and an ultrasonography diagnosis was made. After obtaining final diagnosis sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the test was calculated in various types of swelling. Results: In case of an inflammatory swelling, ultrasonography had a sensitivity of 100%, specificity of 89.5%, PPV of 84.6%, NPV of 100%, and accuracy of 93.3%. In cystic swellings, ultrasonography had a sensitivity of 85.7%, specificity of 100%, PPV of 100%, NPV of 95.8%, and accuracy of 96.67%. In nonodontogenic benign tumor, ultrasonography had a sensitivity of 100%, specificity of 100%, PPV of 100%, NPV of 100%, and accuracy of 100%. In malignant swellings, ultrasonography had a sensitivity of 80%, specificity of 100%, PPV of 100%, NPV of 96.2%, and accuracy of 96.67%. Conclusion: From the present study, it can be concluded that ultrasonography is highly accurate in diagnosing benign neoplasms, followed by soft tissue cystic swellings and malignant neoplasms, followed by inflammatory swellings of the head and neck region. more...
- Published
- 2017
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29. Cytochrome P450 oxidoreductase deficiency: Novel cause of ambiguity with primary amenorrhea
- Author
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Varsha S. Jagtap, Nalini S. Shah, Kranti Khadilkar, Anurag R. Lila, and Tushar Bandgar
- Subjects
lcsh:RC648-665 ,business.industry ,Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,030209 endocrinology & metabolism ,Ambiguity ,Bioinformatics ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Cytochrome P450 Oxidoreductase Deficiency ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Medicine ,lcsh:Diseases of the digestive system. Gastroenterology ,030212 general & internal medicine ,lcsh:RC799-869 ,Letters to the Editor ,business ,Primary amenorrhea ,media_common - Published
- 2017
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30. Stability and effects of muscle transplantation for very large angle esotropia: A study of 22 patients
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Monika Jethani, Nirzari S. Shah, Sonal Amin, and Jitendra Jethani
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Eye Movements ,genetic structures ,medicine.medical_treatment ,Ophthalmologic Surgical Procedures ,Severity of Illness Index ,03 medical and health sciences ,0302 clinical medicine ,lcsh:Ophthalmology ,Severity of illness ,medicine ,Humans ,resection ,Eye surgery ,Prolene ,Retrospective Studies ,Vision, Binocular ,Large angle esotropia ,Esotropia ,true muscle transplantation ,business.industry ,Retrospective cohort study ,medicine.disease ,eye diseases ,Surgery ,Ophthalmology ,Oculomotor Muscle ,Treatment Outcome ,lcsh:RE1-994 ,Oculomotor Muscles ,030221 ophthalmology & optometry ,Female ,Original Article ,recession ,sense organs ,business ,Orthoptic ,030217 neurology & neurosurgery ,Ophthalmologic Surgical Procedure ,Follow-Up Studies - Abstract
Purpose: A very large angle esotropia is characterized by an angle more than 80 prism diopters (pd). A single eye surgery would not correct such a large angle. Supramaximal recessions and resection would lead to restriction of ocular motility. We present a series of 22 patients with large angle esotropia treated with muscle transplantation. Methods: A total of 22 patients (14 males and 8 females) were included in the study. All the patients had a minimum of 80 base out deviation in primary position. All patients underwent thorough preoperative orthoptic checkup and refraction. The patients were followed up on day 1, day 30, at 6 months, at 1 year, and 2 years. All the patients underwent standard muscle transplantation, where the resected extra stump of lateral rectus was transplanted to the medial rectus using 6-0 prolene which was recessed by a standard recession technique. Results: The mean age of the 22 patients was 32.21 ± 13.1 years. The mean preoperative angle was 92.4 ± 13.5 pd base out. The mean postoperative angle at 2-year follow-up was 12.3 ± 9.9 pd. The average correction achieved per mm was 4.1 ± 0.3 pd. The adduction restriction was more...
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- 2017
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31. Long-term cardiac (valvulopathy) safety of cabergoline in prolactinoma
- Author
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Shruti Khare, Prafulla Kerkar, Nalini S. Shah, Tushar Bandgar, Anurag R. Lila, Rishikesh Patil, and Milind S. Phadke
- Subjects
medicine.medical_specialty ,Cabergoline ,Heart malformation ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,030204 cardiovascular system & hematology ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Interquartile range ,valvulopathy ,Internal medicine ,medicine ,Clinical significance ,lcsh:RC799-869 ,Prolactinoma ,Mitral regurgitation ,lcsh:RC648-665 ,Cumulative dose ,business.industry ,medicine.disease ,Surgery ,medicine.anatomical_structure ,prolactinoma ,Pulmonary valve ,Cardiology ,Original Article ,lcsh:Diseases of the digestive system. Gastroenterology ,business ,medicine.drug - Abstract
Background: Clinical relevance of association of cabergoline use for hyperprolactinemia and cardiac valvulopathy remains unclear. Objective: The aim of the study was to determine the prevalence of valvular heart abnormalities in patients taking cabergoline for the treatment of prolactinoma and to explore any associations with the cumulative dose of drug used. Design: A cross-sectional echocardiographic study was performed in patients who were receiving cabergoline therapy for prolactinoma. Results: Hundred (61 females, 39 males) prolactinoma cases (81 macroprolactinoma and 19 microprolactinoma) were included in the study. The mean age at presentation was 33.9 ± 9.0 years (range: 16–58 years). The mean duration of treatment was 53.11 ± 43.15 months (range: 12–155 months). The mean cumulative dose was 308.6 ± 290.2 mg (range: 26–1196 mg; interquartile range: 104–416 mg). Mild mitral regurgitation was present in one patient (cumulative cabergoline dose 104 mg). Mild tricuspid regurgitation was present in another two patients (cumulative cabergoline dose 52 mg and 104 mg). Aortic and pulmonary valve functioning was normal in all the cases. There were no cases of significant valvular regurgitation (moderate to severe, Grade 3–4). None of the patients had morphological abnormalities such as thickening, calcification, and restricted mobility of any of the cardiac valves. Conclusion: Cabergoline appears to be safe in patients with prolactinoma up to the cumulative dose of ~300 mg. The screening for valvulopathy should be restricted to those with higher cumulative cabergoline exposure. more...
- Published
- 2017
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32. Post herpetic frey's syndrome
- Author
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Vijay K Asrani and Jigna S Shah
- Subjects
medicine.medical_specialty ,glycopyrrolate ,During meal ,Case Report ,03 medical and health sciences ,0302 clinical medicine ,stomatognathic system ,medicine ,Frey's syndrome ,Herpes zoster infection ,Glycopyrrolate ,business.industry ,030206 dentistry ,medicine.disease ,Botulinum toxin ,Dermatology ,Temporomandibular joint ,Parotid gland ,medicine.anatomical_structure ,herpes infection ,minor-starch iodine test ,Surgery ,Oral Surgery ,Complication ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Frey's syndrome is characterized by unilateral sweating and flushing of the skin in the area of the parotid gland, occurring during meal, or on salivary stimulation. It is a common complication following surgery/injury in the parotid gland region/temporomandibular joint surgery; however, very few cases have been reported of its occurrence following herpetic infection. It is important for the clinician to recognize its unusual symptoms as early as possible to prevent its potential negative social and psychological effect on the patient. It is diagnosed on clinical presentation and confirmed by objective testing methods. The treatment ranges from topical application of glycopyrrolate to local injections of botulinum toxin and lastly to surgical intervention. An interesting case of Frey's syndrome is presented in a young patient having the previous history of herpes zoster infection, which was diagnosed clinically and confirmed by starch-iodine test and was successfully treated with topical application of glycopyrrolate. more...
- Published
- 2017
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33. Study of fingerprint patterns in hypertensive patients
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Dilip Kumar Mehta, R. Shrestha, D.I. Mansur, R. Shakya, M.K. Haque, S. Shah, and B. Timalsina
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business.industry ,Fingerprint (computing) ,Medicine ,Pattern recognition ,Artificial intelligence ,Anatomy ,business ,Pathology and Forensic Medicine - Published
- 2016
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34. Ventriculoperitoneal shunt tube infection and changing pattern of antibiotic sensitivity in neurosurgery practice: Alarming trends
- Author
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Vikas Kumar, Daljit Singh, Ankit S Shah, Poonam Sood Loomba, Anita Jagetia, and Hukum Singh
- Subjects
Male ,medicine.medical_specialty ,medicine.drug_class ,Antibiotic sensitivity ,Antibiotics ,Infections ,medicine.disease_cause ,Ventriculoperitoneal Shunt ,Neurosurgical Procedures ,03 medical and health sciences ,0302 clinical medicine ,Antibiotic resistance ,medicine ,Humans ,Practice Patterns, Physicians' ,Bacteria ,business.industry ,medicine.disease ,Anti-Bacterial Agents ,Shunt (medical) ,Hydrocephalus ,Surgery ,Neurology ,Staphylococcus aureus ,030220 oncology & carcinogenesis ,Female ,Neurology (clinical) ,Neurosurgery ,business ,Staphylococcus ,030217 neurology & neurosurgery - Abstract
Introduction: Infection associated with a ventriculoperitoneal shunt is a severe complication with a high morbidity and substantial mortality. There are no guidelines to choose antibiotics in case of shunt infection. Most surgeons use antibiotics of their choice whereas limited centres follow their own antibiotic policy. An alarming increase in antibiotic resistance has led to rising morbidity and mortality. Materials and Methods: This was a retrospective analysis of patients who underwent ventriculoperitoneal shunt surgery between January 2010 and December 2015 at our institution. Shunt tubes and cerebrospinal fluid were sent for culture and sensitivity in patients who were suspected clinically of having shunt tube infections. The processing of the samples was done by standard techniques, and the identification of the organism along with its sensitivity pattern was performed using Vitek 2 system. Results: A total of 1186 ventriculoperitoneal shunt surgeries were performed during this period at our institute in patients of all age groups. There were 757 (63.8%) male and 429 (36.2%) female patients. A total of 156 samples of patients were sent for culture and sensitivity during this period, out of which 79 (50.6%) samples had growth of an organism either in the cerebrospinal fluid [36 (23.1%)], shunt tubing [16 (10.2%)], or in both [27 (17.3%)]. The most common organisms grown in the cultures were Staphylococcus aureus [65 (82.3%)] or coagulase-negative Staphylococcus [22 (25.3%)] in the Gram-positive group and Escherichia coli [17 (21.5%)] in the Gram-negative group. Over the last 6 years, the sensitivity pattern of both Gram-negative and Gram-positive bacteria has shown alarming decreasing sensitivity for various commonly used antibiotics. Conclusion: Ventriculoperitoneal shunt infection has become an important concern in cases of hydrocephalus. Due to the development of a high proportion of antibiotic resistance, we recommend an empirical therapy of antibiotic therapy for prophylaxis and suspected infection in ventriculoperitoneal shunt surgery. more...
- Published
- 2016
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35. Lymphocytic hypophysitis in nonpregnant middle-aged females mimicking pituitary adenoma
- Author
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J Gandhi, Nalini S. Shah, Shruti Khare, and S Sankhe
- Subjects
Pathology ,medicine.medical_specialty ,Lymphocytosis ,Hypophysitis ,business.industry ,Pituitary Diseases ,lcsh:R ,lcsh:Medicine ,General Medicine ,medicine.disease ,Letter to Editor ,Pituitary adenoma ,Immunology ,medicine ,Humans ,Female ,medicine.symptom ,business - Published
- 2016
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36. Dr. Nitin Dhende
- Author
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Rasik S. Shah
- Subjects
business.industry ,Pediatrics, Perinatology and Child Health ,Library science ,Medicine ,Surgery ,Obituary ,business - Published
- 2016
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37. Monocular Blindness due to Central Retinal Artery Occlusion Post Spine Surgery
- Author
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Munjal S Shah, Himanshu Parmar, Saurav N Nanda, Jay Shah, and Vinod Agrawal
- Subjects
medicine.medical_specialty ,Spine surgery ,business.industry ,Ophthalmology ,medicine ,Central retinal artery occlusion ,Monocular Blindness ,medicine.disease ,business - Published
- 2014
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38. Maternal obesity and pregnancy outcome
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Rashmi S. Shah and Rama Vaidya
- Subjects
Pregnancy ,medicine.medical_specialty ,business.industry ,Obstetrics ,Medicine ,business ,medicine.disease ,Obesity ,Outcome (game theory) - Published
- 2014
- Full Text
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39. Pioglitazone: Hype and hope
- Author
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Anurag R. Lila, Nalini S. Shah, Swati Jadhav, Tushar Bandgar, and Vyankatesh Shivane
- Subjects
medicine.medical_specialty ,Pioglitazone ,business.industry ,lcsh:R ,lcsh:Medicine ,India ,General Medicine ,Asian People ,Diabetes Mellitus, Type 2 ,Humans ,Hypoglycemic Agents ,Medicine ,Thiazolidinediones ,Insulin Resistance ,business ,Intensive care medicine ,medicine.drug - Published
- 2014
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40. Bone mineral density and factors influencing it in Asian Indian population with type 2 diabetes mellitus
- Author
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Padmavathy S. Menon, Vyankatesh Shivane, Nalini S. Shah, Vimal Nambiar, Tushar Bandgar, and Sadishkumar Kamalanathan
- Subjects
musculoskeletal diseases ,obesity ,medicine.medical_specialty ,type 2 diabetes mellitus ,vitamin D deficiency ,Endocrinology, Diabetes and Metabolism ,Population ,Physiology ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Asian Indian ,Endocrinology ,Internal medicine ,Diabetes mellitus ,medicine ,Vitamin D and neurology ,lcsh:RC799-869 ,education ,Glycemic ,Bone mineral ,education.field_of_study ,lcsh:RC648-665 ,business.industry ,Type 2 Diabetes Mellitus ,medicine.disease ,Obesity ,Original Article ,lcsh:Diseases of the digestive system. Gastroenterology ,bone mineral density ,business - Abstract
Objective: To assess bone mineral density (BMD) in type 2 diabetes mellitus (T2DM) patients and its relation, if any, to clinical, hormonal and metabolic factors. Materials and Methods: A prospective evaluation of 194 T2DM patients (97 men and 97 women) was carried out. BMD was done with dual energy X-ray absorptiometry (DXA) at the lumbar spine and total hip. Physical activity, nutritional intake and sunlight exposure were calculated. Biochemical and hormonal tests included serum 25 hydroxy vitamin D [25(OH) D], parathyroid hormone, estrogen, testosterone and urinary calcium-creatinine ratio. Glycosylated hemoglobin and complete lipid profiles were done in patients with diabetes. Five hundred and seventy one non-diabetic controls (262 males and 309 females) were evaluated for BMD alone. Results: BMD was normal (Z score > -2) in 156 (80.5%) and low (Z score ≤ -2) in 38 (19.5%) patients in the diabetes study group. BMD in the diabetes group was significantly higher than the control group in both sexes at the hip and spine. The difference was no longer significant on analysis of a BMI matched control subgroup. Weight and BMI showed significant correlation to BMD. Duration of T2DM, degree of glycemic control, use of drugs like statins and thiazolidinediones, 25(OH) D levels, calcium intake, sunlight exposure and physical activity did not significantly affect BMD in this cohort of individuals with diabetes. Conclusions: Bone mineral density of Asian Indian T2DM subjects was similar to that of healthy volunteers in this study. more...
- Published
- 2014
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41. Experimental study on effect of hydroalcoholic extract of Emblica officinalis fruits on glucose homeostasis and metabolic parameters
- Author
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Pinakin D Jadav, Ramesh K Goyal, Snehal S. Patel, P. R. Tirgar, and Rajendra S Shah
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,streptozotocin ,chemistry.chemical_compound ,Pharmacological Study ,Diabetes mellitus ,Internal medicine ,oxidative stress ,Medicine ,Glucose homeostasis ,anti-hyperlipidemic ,Triglyceride ,Cholesterol ,business.industry ,anti-oxidant ,Insulin ,Hypertriglyceridemia ,nutritional and metabolic diseases ,General Medicine ,medicine.disease ,Streptozotocin ,Anti-diabetic ,polyphenol ,Endocrinology ,chemistry ,Emblica officinalis ,medicine.symptom ,business ,Polydipsia ,medicine.drug - Abstract
Polyphenols from natural source are potential therapeutics that act alone or supplement anti-diabetic drugs in the prevention and treatment of diabetes. The present investigation was undertaken to study the effect of hydroalcoholic extract (HE) of fruits of Emblica officinalis on type 1 diabetic rats. Diabetes was induced by streptozotocin (STZ) (45 mg/kg i.v.). HE (100 mg/kg, p.o.) was administered for 4 weeks and at the end of treatment, blood samples were collected and analyzed for various biochemical parameters. STZ produced a diabetic state exhibiting all the cardinal symptoms such as loss of body weight, polydipsia, polyuria, glucosuria, polyphagia, hypoinsulinemia, and hyperglycemia associated with hypercholesterolemia and hypertriglyceridemia. Treatment with HE prevented cardinal symptoms and caused significant decrease in fasting serum glucose, AUC glucose , cholesterol, triglyceride, low-density lipoprotein (LDL) and very LDL in diabetic rats. However, insulin, AUC insulin , and serum high-density lipoprotein level were not significantly altered by treatment. Treatment also reduced lipid peroxidation and increased anti-oxidant parameters in the liver homogenates of diabetic rats. Polyphenol enriched fraction of HE significantly improved disarranged carbohydrate and lipid metabolism of chemically induced diabetes in rats. The mechanism of its anti-diabetic activity appears to be either improvement in peripheral glucose utilization, increased insulin sensitivity, or anti-oxidant property. more...
- Published
- 2013
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42. Neoadjuvant bronchoscopic intervention: Bridge to lung parenchyma sparing surgery
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Prashant N. Chhajed, Parth S Shah, Arvind H Kate, Nikhil Shukla, and Shishir Shetty
- Subjects
medicine.medical_specialty ,Oncology ,business.industry ,Intervention (counseling) ,Parenchyma ,Medicine ,Radiology, Nuclear Medicine and imaging ,General Medicine ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,business ,lcsh:RC254-282 ,Bridge (interpersonal) ,Surgery - Published
- 2013
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43. Current concepts in blood glucose monitoring
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Vyankatesh Shivane, Tushar Bandgar, Kranti Khadilkar, Nalini S. Shah, and Anurag R. Lila
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medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Review Article ,Bioinformatics ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Endocrinology ,Diabetes mellitus ,Blood glucose monitoring system ,medicine ,glycated haemoglobin ,lcsh:RC799-869 ,Intensive care medicine ,Glycated haemoglobin ,Glycemic ,Blood glucose monitoring ,lcsh:RC648-665 ,medicine.diagnostic_test ,Continuous glucose monitoring ,business.industry ,Monitoring system ,medicine.disease ,glycemic variability ,lcsh:Diseases of the digestive system. Gastroenterology ,continuous glucose monitoring ,business ,self-monitored blood glucose - Abstract
Blood glucose monitoring has evolved over the last century. The concept of adequate glycemic control and minimum glycemic variability requires an ideal, accurate and reliable glucose monitoring system. The search for an ideal blood glucose monitoring system still continues. This review explains the various blood glucose monitoring systems with special focus on the monitoring systems like self- monitored blood glucose (SMBG) and continuous glucose monitoring system (CGMS). It also focuses on the newer concepts of blood glucose monitoring and their incorporation in routine clinical management of diabetes mellitus. more...
- Published
- 2013
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44. Laparoscopic management of impalpable undescended testes: 20 years′ experience
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Namita C Chaudhari, Rupin S Shah, Vinay G Mehendale, Sharad N Shenoy, and Alap V. Mehendale
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Open surgery ,medicine.medical_treatment ,lcsh:Surgery ,lcsh:RD1-811 ,testis ,Laparoscopic surgical procedures ,laparoscopic surgical procedures ,Surgery ,Testicular vessels ,medicine ,Original Article ,lcsh:Diseases of the digestive system. Gastroenterology ,Laparoscopic Orchiopexy ,Orchiopexy ,Abnormalities ,lcsh:RC799-869 ,Stage (cooking) ,Laparoscopy ,business ,cryptorchidism - Abstract
BACKGROUND: Laparoscopy is the best available method to manage impalpable undescended testes. We performed our first laparoscopic orchiopexy in June 1992 and found good results in consecutive cases with laparoscopic orchiopexy over last 20 years. MATERIALS AND METHODS: From June 1992 to May 2012, 241 patients with 296 impalpable testes were operated upon by laparoscopic approach. One-stage laparoscopic orchiopexy was performed in 152 cases, while two-stage Fowler — Stephens laparoscopic orchiopexy was performed in 55 cases. Laparoscopic orchiectomy was required in 20, and in 21 patients testes were absent. One-sided laparoscopic orchiopexy was performed in a male pseudo hermaphrodite. RESULTS: None of the testis atrophied after two-stage Fowler — Stephens laparoscopic orchiopexy, while in 152 cases of single-stage orchiopexies one testes atrophied. One patient developed malignant change in the testis, 6 years after orchiopexy. CONCLUSIONS: Laparoscopy is the best way to diagnose impalpable undescended testes. No other imaging investigation was required. Single-stage laparoscopic orchiopexy for low level undescended testis has very good results. For high-level undescended testis and when one-stage mobilisation is difficult, two-stage Fowler — Stephens orchiopexy has excellent results. Minimum 4 months should separate first and second stage of laparoscopic Fowler — Stephens procedure. Even when open orchiopexy is being done for intra-canalicular testes in a child, it is advisable to be ready with laparoscopy if necessary, at the same time, in case open surgery fails to mobilise the testicular vessels adequately. more...
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- 2013
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45. Clinical practice guidelines on menopause: FNx01An executive summary and recommendations
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Rashmi S. Shah, Sonia Malik, Meeta, Nirmala Vaze, Neelam Agarwal, and Leela Digumarti
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Clinical Practice ,Menopause ,medicine.medical_specialty ,Health (social science) ,Executive summary ,business.industry ,Family medicine ,medicine ,Alternative medicine ,Medicine (miscellaneous) ,business ,medicine.disease - Published
- 2013
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46. Surgical esthetic correction for gingival pigmentation: Case series
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Shilpi S Shah
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Gingival hyperpigmentation ,Orthodontics ,medicine.medical_specialty ,business.industry ,Pigmented gums ,Dentistry ,Plastic surgery ,Gingival pigmentation ,Depigmentation ,Gummy smile ,Medicine ,In patient ,sense organs ,medicine.symptom ,business - Abstract
Gingival pigmentation is a major concern for a large number of patients visiting the dentist. The patients with excessive gingival display and pigmentation are more concerned esthetically. Most pigmentation is caused by five primary pigments out of which melanin shows the maximum incidence rate. Melanin hyper pigmentation usually does not present as a medical problem, but patients may complain about their unesthetic black gums. The gingiva is the most frequently pigmented intraoral tissue, with the highest rate observed in the area of the incisors Esthetic periodontal plastic surgery is a boon in patients having dark gums and gummy smile. This article offers a retrospective case series of gingival depigmentation by epithelial excision using scalpel. Out of the several techniques employed for depigmentation, the surgical technique using scalpel is still the first and most popular technique. Experience of 4 years is put forward with critical analysis of the surgical technique including the various advantages and disadvantages. This is a case report representing a simple surgical technique of de-epithelization which has been successfully used to treat gingival hyperpigmentation caused by excessive melanin deposition and highlights the relevance of an esthetically pleasing smile especially in smile conscious individuals. Clinical Relevance to Interdisciplinary Dentistry Gingival hyper pigmentation is a very common esthetic complaint reported by patients in various fields of dentistry. Through this case series the dentists can ascertain the various types of techniques mentioned in the following article for treating pigmented gums with pleasing esthetics &acceptable patients satisfaction more...
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- 2012
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47. Promise and pitfalls of molecular markers of thyroid nodules
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Swati Jadhav, Nalini S. Shah, Anurag R. Lila, and Tushar Bandgar
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Thyroid nodules ,Pathology ,medicine.medical_specialty ,gene rearrangements ,Mini Review ,Endocrinology, Diabetes and Metabolism ,Population ,genetic mutations ,Gene mutation ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Thyroid function tests ,Diagnostic modalities ,Endocrinology ,Biopsy ,Medicine ,lcsh:RC799-869 ,education ,education.field_of_study ,lcsh:RC648-665 ,medicine.diagnostic_test ,business.industry ,thyroid nodules ,Molecular markers ,medicine.disease ,Optimal management ,Fine-needle aspiration ,lcsh:Diseases of the digestive system. Gastroenterology ,business - Abstract
Thyroid nodules are common in the general population with a prevalence of 5-7% The initial evaluation of thyroid nodules commonly involves thyroid function tests, an ultrasound (USG) and fine needle aspiration biopsy (FNAB). The optimal management of patients with thyroid nodules with indeterminate cytology is plagued by the lack of highly sensitive and specific diagnostic modalities In this article we attempt to review the available literature on the molecular markers which are increasingly being studied for their diagnostic utility in assessing thyroid nodules. The various molecular markers consist of gene mutations, gene re arrangements, RNA based assays and immunohistochemical markers. The molecular markers definitely would help to optimise the management of such patients. more...
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- 2012
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48. Giant mesenteric fibromatosis in Gardner′s syndrome
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Mithun S Shah, Gopal Sharma, BA Vaswani, PM Shah, Asha Anand, and BJ Parikh
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Gardner's syndrome ,Oncology ,business.industry ,Mesenteric fibromatosis ,Medicine ,Anatomy ,business ,medicine.disease - Published
- 2011
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49. Managing non-ketotic childhood hyperglycemia
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Vyankatesh Shivane, Tushar Bandgar, Nalini S. Shah, and Anurag R. Lila
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medicine.medical_specialty ,Adolescent ,business.industry ,lcsh:R ,lcsh:Medicine ,General Medicine ,medicine.disease ,Diabetes Mellitus, Type 1 ,Diabetes Mellitus, Type 2 ,Hyperglycemia ,Humans ,Medicine ,Medical emergency ,Child ,business ,Intensive care medicine ,Algorithms - Published
- 2011
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50. Prevalence of upper airway obstruction in patients with apparently asymptomatic euthyroid multi nodular goitre
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Padmavathy S. Menon, Varsha S. Jagtap, Sunil K. Menon, Anurag R. Lila, Tushar Bandgar, Nalini S. Shah, and Vijaya Sarathi
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medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Physical examination ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Asymptomatic ,Pulmonary function testing ,pulmonary function test ,Endocrinology ,Multi nodular goitre ,medicine ,Euthyroid ,lcsh:RC799-869 ,lcsh:RC648-665 ,medicine.diagnostic_test ,business.industry ,Thyroid ,respiratory system ,Airway obstruction ,Multinodular goitre ,medicine.disease ,Surgery ,Exact test ,medicine.anatomical_structure ,upper airway obstruction ,lcsh:Diseases of the digestive system. Gastroenterology ,Original Article ,Radiology ,medicine.symptom ,business - Abstract
Aims: To study the prevalence of upper airway obstruction (UAO) in "apparently asymptomatic" patients with euthyroid multinodular goitre (MNG) and find correlation between clinical features, UAO on pulmonary function test (PFT) and tracheal narrowing on computerised tomography (CT). Materials and Methods: Consecutive patients with apparently asymptomatic euthyroid MNG attending thyroid clinic in a tertiary centre underwent clinical examination to elicit features of UAO, PFT, and CT of neck and chest. Statistical Analysis Used: Statistical analysis was done with SPSS version 11.5 using paired t-test, Chi square test, and Fisher′s exact test. P value of more...
- Published
- 2011
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