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Introduction: Oral health is an essential non-integrated part of general health that plays a vital role in preventing chronic diseases. The oral cavity acts as a suitable environment for the proliferation of bacteria by forming a connecting link to invade the tissues through direct contact from outside. For the past few decades, there has been increased resistance of human pathogenic bacteria to the currently used antibiotics and chemotherapeutics for tooth decay, gingivitis, periodontitis and fungal infection among different age groups. Hence, the search has shifted to traditional plants and natural products, which are a good alternative. To create oral hygiene solutions for the prevention of oral infections, several ayurvedic ingredients, including Andrographis paniculata and Mimusops elengi, have been tested for their effectiveness against dental pathogens. The present investigation's purpose is to determine the minimum inhibitory concentration-based antibacterial efficiency of Andrographis paniculata and Mimusops elengi against Streptococcus mutans, Lactobacillus acidophilus, Actinomyces and Candida albicans., Methodology: Antimicrobial activity of herbal extracts was determined using the agar well diffusion method. Ethanolic extracts were prepared using a cold extraction method whereas Dimethyl sulfoxide and water were used as dissolution solvents. The diluted herbal extract sample was used as the test sample, while the positive control used was an antibiotic solution and the negative control used was dissolution solvents. The samples were implanted, the bacteria along with the culture media were incubated, and the zone of inhibition was measured., Results: The Minimum inhibitory concentration and zones of inhibition of Andrographis Paniculata and Mimusops Elengi showed significant antibacterial efficacy when compared with standards., Conclusion: Andrographis Paniculata and Mimusops Elengi may be used as an efficient addition to conventional care in the management of oral disorders, according to their antimicrobial efficacy., Competing Interests: There are no conflicts of interest., (Copyright: © 2023 Journal of Oral and Maxillofacial Pathology.)

Sarcoidosis is a granulomatous disorder of multiple organs, with lungs and lymphatic systems being the most frequently affected sites of the body. It was first reported in 1877 and has continued to engross both clinicians and scientists since that time. Because sarcoidosis being a diagnosis of exclusion, it demands the physician to rule out all the possible diagnosis. Most of the patients remain asymptomatic and this makes the disease remain unnoticed for a prolonged period. Later after years, the disease could be diagnosed after witnessing the patient being symptomatic or suffering from organ failures. It could affect middle aged people of any sexes, often its clinical features correlate with tuberculosis. On immunological and histopathological examination, it reveals noncaseating granuloma in simple terms. Glucocorticoids remain the standard drug now and then. Further research has to be done to know the exact pathogenesis, early detection and betterment in treatment plan of sarcoidosis. The current review article gives a brief knowledge about etiopathogenesis, Clinical features, upgraded diagnostic methods such as biomarkers detection and the organized treatment plan to treat sarcoidosis., Competing Interests: There are no conflicts of interest., (Copyright: © 2022 Journal of Oral and Maxillofacial Pathology.)