1. POLYMORPHISM OF CLINICAL MANIFESTATIONS OF CRYOGLOBULINEMIA-RELATED VASCULITIS ASSOCIATED WITH CHRONIC HEPATITIS С VIRUS INFECTION
- Author
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S. Yu. Milovanova, L. V. Kozlovskaya, and N. B. Gordovskaya
- Subjects
mixed cryoglobulinemia ,Pathology ,medicine.medical_specialty ,business.industry ,General Medicine ,030204 cardiovascular system & hematology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Chronic hepatitis ,Fibrosis ,cryoglobulinemic vasculitis ,Mixed cryoglobulinemia ,medicine ,Medicine ,030211 gastroenterology & hepatology ,In patient ,chronic hepatitis с ,business ,Cryoglobulinemic vasculitis - Abstract
The authors investigated the clinical picture characteristics and prognostic value of HCV-associated cryoglobulinemic vasculitis variations. More rapid fibrosis formation was shown in chronic hepatitis С patients with CG as compared with those without CG which allows considering CG the marker of the chronic hepatitis C. It was found that the frequency and severity of some extrahepatic lesions and immunological changes in patients with CG were expressed more greatly than those in patients without CG, and these data were statistically significant. The results obtained confirm the role of cryoglobulinemic vasculitis as an important mechanism for development of systemic lesions in hepatitis-C. The importance of CG as a predictor of the malignant В-cell lymphoproliferation in patients with chronic hepatitis С was proved.
- Published
- 2016
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