1. Aluminum Nanoholes for Optical Biosensing
- Author
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María C. Moreno-Bondi, Javier L. Urraca, Carlos Angulo Barrios, Rosa Puchades, Víctor Canalejas-Tejero, Sonia Herranz, Miquel Avella-Oliver, and Ángel Maquieira
- Subjects
Optical biosensing ,Materials science ,lcsh:Biotechnology ,Clinical Biochemistry ,Nanoparticle ,Nanotechnology ,Biosensing Techniques ,molecularly imprinted polymer ,Transfer printing ,Article ,Light scattering ,metal nanoholes ,nanopatterning ,Surface plasmon resonance ,lcsh:TP248.13-248.65 ,QUIMICA ANALITICA ,Optica ,Polycarbonate ,Metal nanoholes ,Nanoscopic scale ,Molecularly imprinted polymer ,Telecomunicaciones ,Polycarboxylate Cement ,Materiales ,Photopolymerization ,optical biosensing ,Nanopatterning ,nanohole arrays ,transfer printing ,General Medicine ,Photochemical Processes ,Nanostructures ,visual_art ,aluminum ,photopolymerization ,visual_art.visual_art_medium ,Nanohole arrays ,Biosensor ,surface plasmon resonance ,Aluminum - Abstract
[EN] Sub-wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio)sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly localized optical fields that can effectively interact with biomolecules and/or nanoparticles on the nanoscale. As the metal of choice, aluminum exhibits good optical and electrical properties, is easy to manufacture and process and, unlike gold and silver, its low cost makes it very promising for commercial applications. However, aluminum has been scarcely used for biosensing purposes due to corrosion and pitting issues. In this short review, we show our recent achievements on aluminum nanohole platforms for (bio)sensing. These include a method to circumvent aluminum degradation-which has been successfully applied to the demonstration of aluminum nanohole array (NHA) immunosensors based on both, glass and polycarbonate compact discs supports-the use of aluminum nanoholes operating as optical waveguides for synthesizing submicron-sized molecularly imprinted polymers by local photopolymerization, and a technique for fabricating transferable aluminum NHAs onto flexible pressure-sensitive adhesive tapes, which could facilitate the development of a wearable technology based on aluminum NHAs., The authors gratefully acknowledge financial support from MINECO projects, Spain (TEC2012-31145, CTQ2012-37573-C02 and CTQ 2013-45875-R).
- Published
- 2015
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