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Introduction. Acute appendicitis is the most common cause of the acute abdomen. Based on the idea that appendicitis is a progressive disease eventually leading to perforation, removal of the appendix is the gold standard of treatment. Material and Methods. The objective of the study is to determine if there is any difference in the occurrence of postoperative complications, and if hospitalization differs depending on the appendicitis surgery method used with the patients. A retrospective analysis was made using the data from the hospital sample of patients admitted to the University Hospital in Foca in the period from January 2019 to December 2021. Results. In the period that was retrospectively analyzed, 107 patients diagnosed with acute appendicitis were operated on. There was no statistically significant difference between the treated groups in relation to the degree of appendicitis, type and duration of symptoms, diagnostic procedures and the time that had elapsed from admission to surgery. The Alverado Score in the probable appendicitis group was 41.1%. The most common symptoms were palpation sensitivity in the inguinal region (84.1%), and pain in the right lower quadrant (69.1%), intraoperative findings of uncomplicated appendicitis 58%, and 25.2% intraoperative findings inconsistent with the pathohistological ones. Conclusion. Acute appendicitis is one of the most common emergency surgical conditions, which requires surgical intervention if not treated in time, and causes life-threatening consequences. Surgical treatment with selected techniques for faster establishment of the gastrointestinal tract function, shorter stay in the hospital, faster recovery and return to daily activities. [ABSTRACT FROM AUTHOR]

Introduction. De Garengeot’s hernia is a rare type of femoral hernia that contains the appendix within the hernia sac and it is found in 0.5–5% of cases. The incidence of appendicitis within the de Garengeot’s hernia is 0.08–0.13%. We present a case of de Garengeot’s hernia with a gangrenous appendicitis and an extensive literature review of published cases. Case Report. We present a case of a 68-year-old woman who underwent urgent surgery due to an incarcerated femoral hernia and preoperatively undiagnosed de Garengeot’s hernia with a gangrenous appendicitis within the femoral hernia sac. Conclusion. De Garengeot’s hernia is most commonly diagnosed intraoperatively and requires immediate surgery in order to avoid complications. There are no recommendations regarding the choice of surgical procedure for femoral defect repair. [ABSTRACT FROM AUTHOR]

Introduction. Laparoscopic assisted vaginal hysterectomy is a surgical procedure with uterine artery ligation followed by vaginal removal of the uterus. The first laparoscopic assisted vaginal hysterectomy included mild uterine prolapse and uterine fibroids (15 patients, 62.5%). The surgery was carried out in two stages: the first, laparoscopic stage and the second, vaginal stage. The laparoscopic stage included mobilization of the bladder, ovaries and uterus to the level of uterine vessels. In the second stage, the cervix was approached vaginally and detached from the urinary bladder, after which the uterus with cervix and adnexa were removed through the vagina. Results. The average age of patients was 56.8 years, on average, the surgeries lasted 140 minutes and the mean blood loss was 190 ml. Two (8.3%) patients experienced bladder and ureteral injuries which were resolved by urologists. Laparoscopic assisted vaginal hysterectomy was the only procedure performed in 5 (20.8%) patients, whereas it was combined with anterior and/or posterior colporrhaphy in 14 (58.4%), with pelvic lymphadenectomy in 3 (12.5%) patients, and with uterine morcellation in 2 (8.3%) patients. Conclusion. There are no published controlled trials related to the use of laparoscopic assisted vaginal hysterectomy and total laparoscopic hysterectomy in Serbia. This paper presents the preliminary results of the laparoscopic assisted vaginal hysterectomy in 24 patients, comparing them with other techniques of hysterectomy conducted at the Clinic of Gynecology and Obstetrics, Clinical Center of Vojvodina in Novi Sad in the period 2014 - 2017. Laparoscopic assisted vaginal hysterectomy is a good option for surgical treatment of patient with combined pathology of genital organs. [ABSTRACT FROM AUTHOR]

Adrenal cavernous hemangiomas are extremely rare non-functioning benign tumors. The majority of adrenal cavernous hemangiomas are diagnosed incidentally after surgery by histopathological examination. Case Report. We report a clinical case of a 57-year-old woman with adrenal cavernous hemangioma. On admission, the patient's adrenal-related hormones were in the reference range, so adrenal endocrine dysfunction was ruled out. The computed tomography scan revealed a well-circumscribed, round, heterogeneous right adrenal mass (32.3 x 55.4 mm). Iodinated contrast enhanced abdominal computed tomography showed a slight inhomogeneity. In this case, preoperative radiologic findings and absence of signs of local invasion indicated laparoscopic adrenalectomy. The patient underwent right transperitoneal adrenalectomy. Microscopic evaluation showed a sinusoidal dilatation and fibrotic septa, so postoperative diagnosis of adrenal cavernous hemangioma was made. Conclusion. In summary, we reported a case of an incidentally discovered non-functioning adrenal cavernous hemangioma treated by laparoscopic surgery. The diagnosis of adrenal cavernous hemangioma may be challenging, and it is commonly made after surgery, since it is frequently confirmed by histopathological examination. [ABSTRACT FROM AUTHOR]

Introduction. Infections caused by fungi of Fusarium species occur in immunocompromised individuals as disseminated diseases. Case Report. This case report presents a 5-year-old boy with acute lymphoblastic leukemia who developed a disseminated fusarium infection during reinduction chemotherapy. Fever was the main symptom and it lasted for 15 weeks. Refractory fever despite broad-spectrum antibiotics, as well as nausea, myalgia, pulmonary symptoms with detection of pulmonary infiltrates, liver and spleen involvement indicated an invasive fungal infection. The patient received fluconazole, voriconazole, liposomal amphotericin B and caspofungin. Since high temperature was persistent, diagnostic laparoscopy of the abdomen was done. Scattered lesions, up to 2 mm in diameter, were observed macroscopically on the surface of the liver and spleen. The liver culture was positive for Acinetobacter and Fusarium species. After 38 days of therapy with liposomal amphotericin B and 3 days of ciprofloxacin, the patient became afebrile. Itraconazole (according to the antimycogram) was continued during maintenance therapy. Abdominal ultrasound was completely normal after 5 months of treatment with itraconazole. This boy was our first patient with a disseminated fusarium infection. At that time, Fusarium was detected in the hospital water system and in hospital air samples. Conclusion. A timely diagnosis of invasive fungal diseases in children is a big challenge. Over the past decade, there has been an increase in survival rate of patients with invasive fusariosis due to much more common use of voriconazole or combined antifungal therapy. [ABSTRACT FROM AUTHOR]

Endometriosis is defined as a functional endometrial tissue outside the uterine cavity. The ectopic endometrial tissue has been identified after gynecologic laparoscopy or laparotomy procedures in the skin, subcutaneous tissues, abdominal and pelvic wall musculature, and it represents amayor cause of acute or chronic recurrent abdominal or pelvic pain resembling the menstrual cycle. The frequency of abdominal wall endometriosis is approximately 1% of all women who had a cesarean delivery. A 39-year-old patient with a history of one prior Cesarean section, presented with continuous cyclical focal pain at the left part of cesarean scar site for the past 16 months, 23 months after Cesarean section. The patient underwent a mini laparotomy, when endometrioma was completely removed surgically. The PH diagnosis of endometriosis was based on the presence of all elements of the endometrial mucosa (glands, stroma and signs of fresh and old hemorrhage) in an inadequate place (anterior abdominal wall). Endometriosis is difficult to diagnose and it is often mistaken for other conditions such as a suture granuloma, incisional hernia, primary or metastatic cancer. Endometriosis can be prevented only with good surgical techniques and clinical practice as well as the proper care during primary surgery. [ABSTRACT FROM AUTHOR]

Introduction. Kidney transplantation is a treatment modality for patients with end-stage renal disease. Nowadays, in the Western world, laparoscopic living donor nephrectomy represents the treatment of choice for graft retrieval. The aim of this paper was to present the laparoscopic living donor left nephrectomy technique. Results. Only one living donor nephrectomy has been performed at the Clinical Center of Vojvodina so far. The authors reviewed the literature data on the results and complications of laparoscopic living donor nephrectomies. Conclusion. Laparoscopic living donor nephrectomy is a feasible procedure, but according to most authors, it should be performed by surgeons with significant experience in laparoscopic nephrectomy. [ABSTRACT FROM AUTHOR]

Introduction. Polycystic ovary syndrome is the most frequent endocrine disturbance in the reproductive period of women's life and the most frequent cause of anovulatory infertility. Ovulation and pregnancy in patients having polycystic ovary syndrome may be a result of a wide range of therapeutic options, and the treatment assumes a gradual approach - from simple noninvasive to expensive and demanding procedures. Material and Methods. A systematic literature survey concerning the efficiency of particular ovulation induction methods in respect of the reproductive outcome was carried out with the aim of establishing the algorithm for ovulation induction in infertile patients having polycystic ovary syndrome. The search was confined to clinical investigations performed on human subjects, reported in English in the period from the beginning of 2010 to June of 2014. Conclusion. As a conclusion of this systematic survey of the efficiency of ovulation induction methods, which confirms and supplements the knowledge in this field, it is possible to form the algorithm for ovulation induction in infertile patients having polycystic ovary syndrome, consisting of the following subsequent steps: 1) modification of life style, 2) induction with clomiphene citrate 3) use of metformin, 4) use of aromatase inhibitors, 5) application of gonadotropins and laparoscopic ovarian drilling - as a second-line treatment, and 6) assisted reproductive techniques. [ABSTRACT FROM AUTHOR]

Introduction. An abdominal pregnancy is a rare form of ectopic pregnancy and potentially life-threatening condition. It is difficult to make an early diagnosis of abdominal pregnancy. Case Report. We present a case of early primary abdominal pregnancy, diagnosed at 6th gestational week, located in the vesicouterine pouch and treated laparoscopically. Despite the rapidly decreasing serum β-human chorionic gonadotropin levels, the presence of the intraperitoneal blood allowed neither expectant management nor medical treatment, although the patient was hemodinamically stable at that moment. The absence of significant bleeding during the surgery and histopathological finding of placental villi with necrosis confirmed that, in this case, the abdominal pregnancy was already the subject of spontaneous involution. Conclusion. High index of suspicion and carefully interpreted clinical and ultrasound findings are crucial for timely diagnosis of early abdominal pregnancy before the occurrence of massive and potentially fatal intraperitoneal bleeding. [ABSTRACT FROM AUTHOR]

Introduction. Laparoscopic appendectomy is one of the simplest laparoscopic procedures, which is gradually becoming the method of choice in treatment of acute appendicitis due to its advantages over open appendectomy. In South-Eastern Europe the use of laparoscopic appendectomy is still very limited although it is a very simple procedure, suitable for training laparoscopic techniques. Technique of Laparoscopic Appendectomy. This review article describes the position of the patient and surgical team during laparoscopic appendectomy, position of troacars and working instruments which result in expressive cosmetic effect, technique of laparoscopic appendectomy, different ways of securing the base of appendix. Complications of Laparoscopic Appendectomy. This review article describes management of complicated appendicitis, and intra- and post-operative complications. Conclusion. Laparoscopic appendectomy has many advantages over open appendectomy. The risk of wound infection is lower, postoperative pain is weaker and the hospital stay is shorter. [ABSTRACT FROM AUTHOR]

Medical experts are still at issue over the most suitable management of simple neonatal ovarian cysts exceeding 40mm and complex cysts of any size. The authors present surgical treatment of these cysts by classical laparotomy and laparoscopy. The study included 13 newborn babies surgically treated for 6 simple and 7 complex ovarian cysts. The diameter of the cysts ranged from 29 to 102mm. The age of children was from 2 days to 10 months. The open classical laparotomic approach was performed in 8 babies. In the laparotomy group, cystectomy was done in 3 infants with simple cysts. The other 5, presented with ovarian torsion, required salpingo-oophorectomy. Video - assisted cystectomy was the procedure for 3 simplex and one complex cyst with torsion. Laparoscopic adnexectomy was applied in one case with autoamputated cyst. Our small study demonstrates that laparoscopy is as safe and effective as classical laparotomy in managing neonatal ovarian cysts, but with better cosmetic results. [ABSTRACT FROM AUTHOR]