1. Extracellular vesicles in immunomodulation and tumor progression.
- Author
-
Marar C, Starich B, and Wirtz D
- Subjects
- Animals, Disease Progression, Extracellular Vesicles metabolism, Extracellular Vesicles pathology, Humans, Immunotherapy, Neoplasms metabolism, Neoplasms pathology, Neoplasms therapy, Signal Transduction, Tumor Microenvironment, Extracellular Vesicles immunology, Neoplasms immunology, Tumor Escape
- Abstract
Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists.
- Published
- 2021
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