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1. Anal human papillomavirus infection and its relationship with abnormal anal cytology among MSM with or without HIV infection in Japan

Author

Daisuke Shiojiri, Daisuke Mizushima, Misao Takano, Koji Watanabe, Naokatsu Ando, Haruka Uemura, Yasuaki Yanagawa, Takahiro Aoki, Junko Tanuma, Kunihisa Tsukada, Katsuji Teruya, Yoshimi Kikuchi, Hiroyuki Gatanaga, and Shinichi Oka

Subjects
Medicine, Science
Abstract

Abstract Anal high-risk human papillomavirus (hr-HPV) infection is widely considered a cause of anal cancer. However, epidemiological data are quite limited in Japan. This study investigated anal HPV infections and cytological abnormalities among MSM with or without HIV infection. Anal swabs were obtained, and cytological results were examined. Hybrid capture-based methodology was used for hr-HPV genotyping. The exclusion criterion was a history of vaccination against HPV. 644 subjects participated, and the overall prevalence of hr-HPV was 59.7% (95% CI 54.7–62.3), HIV-infected had higher prevalence than HIV-uninfected (68.9% vs 40.6%) p

Published
2021
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2. Anal human papillomavirus infection and its relationship with abnormal anal cytology among MSM with or without HIV infection in Japan

Author

Takahiro Aoki, Yasuaki Yanagawa, Katsuji Teruya, Shinichi Oka, Koji Watanabe, Daisuke Shiojiri, Misao Takano, Kunihisa Tsukada, Daisuke Mizushima, Naokatsu Ando, Haruka Uemura, Yoshimi Kikuchi, Junko Tanuma, and Hiroyuki Gatanaga

Subjects
Adult, Male, medicine.medical_specialty, Multivariate analysis, Science, Anal Canal, HIV Infections, Human papilloma virus, Alphapapillomavirus, Article, Sexual and Gender Minorities, Japan, Risk Factors, Internal medicine, Epidemiology, Genotype, Prevalence, Medicine, Anal cancer, Humans, Risk factor, Human papillomavirus, Genotyping, Anus Diseases, Multidisciplinary, business.industry, Papillomavirus Infections, virus diseases, Middle Aged, medicine.disease, Anus Neoplasms, Vaccination, business
Abstract

Anal high-risk human papillomavirus (hr-HPV) infection is widely considered a cause of anal cancer. However, epidemiological data are quite limited in Japan. This study investigated anal HPV infections and cytological abnormalities among MSM with or without HIV infection. Anal swabs were obtained, and cytological results were examined. Hybrid capture-based methodology was used for hr-HPV genotyping. The exclusion criterion was a history of vaccination against HPV. 644 subjects participated, and the overall prevalence of hr-HPV was 59.7% (95% CI 54.7–62.3), HIV-infected had higher prevalence than HIV-uninfected (68.9% vs 40.6%) p

Published
2021

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