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1. The brain is required for normal muscle and nerve patterning during early Xenopus development

Author

Celia Herrera-Rincon, Vaibhav P. Pai, Kristine M. Moran, Joan M. Lemire, and Michael Levin

Subjects
Science
Abstract

Functions of the embryonic brain prior to regulating behavior are unclear. Here, the authors use an amputation assay in Xenopus laevis to demonstrate that removal of the brain early in development alters muscle and peripheral nerve patterning, which can be rescued by modulating bioelectric signals.

Published
2017
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