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4 results on '"Partha Pratim De"'

1. Whole genome sequencing reveals hidden transmission of carbapenemase-producing Enterobacterales

Author

Kalisvar Marimuthu, Indumathi Venkatachalam, Vanessa Koh, Stephan Harbarth, Eli Perencevich, Benjamin Pei Zhi Cherng, Raymond Kok Choon Fong, Surinder Kaur Pada, Say Tat Ooi, Nares Smitasin, Koh Cheng Thoon, Paul Anantharajah Tambyah, Li Yang Hsu, Tse Hsien Koh, Partha Pratim De, Thean Yen Tan, Douglas Chan, Rama Narayana Deepak, Nancy Wen Sim Tee, Andrea Kwa, Yiying Cai, Yik-Ying Teo, Natascha May Thevasagayam, Sai Rama Sridatta Prakki, Weizhen Xu, Wei Xin Khong, David Henderson, Nicole Stoesser, David W. Eyre, Derrick Crook, Michelle Ang, Raymond Tzer Pin Lin, Angela Chow, Alex R. Cook, Jeanette Teo, Oon Tek Ng, and Carbapenemase-Producing Enterobacteriaceae in Singapore (CaPES) Study Group

Subjects
Science
Abstract

Carbapenemase-producing Enterobacterales cause healthcare-associated infections but modes of transmission are not well understood. Here, the authors find evidence of transmission without direct patient contact, indicating presence of undetected environmental reservoirs, whilst half of the transmission events are likely due to plasmid-mediated transmission.

Published
2022
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2. Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients

Author

Po Ying Chia, Kristen Kelli Coleman, Yian Kim Tan, Sean Wei Xiang Ong, Marcus Gum, Sok Kiang Lau, Xiao Fang Lim, Ai Sim Lim, Stephanie Sutjipto, Pei Hua Lee, Than The Son, Barnaby Edward Young, Donald K. Milton, Gregory C. Gray, Stephan Schuster, Timothy Barkham, Partha Pratim De, Shawn Vasoo, Monica Chan, Brenda Sze Peng Ang, Boon Huan Tan, Yee-Sin Leo, Oon-Tek Ng, Michelle Su Yen Wong, Kalisvar Marimuthu, and for the Singapore 2019 Novel Coronavirus Outbreak Research Team

Subjects
Science
Abstract

Here, the authors sample air and surfaces in hospital rooms of COVID-19 patients, detect SARS-CoV-2 RNA in air samples of two of three tested airborne infection isolation rooms, and find surface contamination in 66.7% of tested rooms during the first week of illness and 20% beyond the first week of illness.

Published
2020
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3. Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters

Author

Kaixi Zhang, Yu Du, Zhangyong Si, Yang Liu, Michelle E. Turvey, Cheerlavancha Raju, Damien Keogh, Lin Ruan, Subramanion L. Jothy, Sheethal Reghu, Kalisvar Marimuthu, Partha Pratim De, Oon Tek Ng, José R. Mediavilla, Barry N. Kreiswirth, Yonggui Robin Chi, Jinghua Ren, Kam C. Tam, Xue-Wei Liu, Hongwei Duan, Yabin Zhu, Yuguang Mu, Paula T. Hammond, Guillermo C. Bazan, Kevin Pethe, and Mary B. Chan-Park

Subjects
Science
Abstract

The authors report the synthesis of an enantiomeric block co-beta-peptide that kills methicillin-resistant Staphylococcus aureus, including biofilm and persister bacterial cells, and disperses biofilms. The copolymer displays antibacterial activity in human ex vivo and mouse in vivo infection models without toxicity.

Published
2019
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4. Author Correction: The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone

Author

Swaine L. Chen, Ying Ding, Anucha Apisarnthanarak, Shirin Kalimuddin, Sophia Archuleta, Sharifah Faridah Syed Omar, Partha Pratim De, Tse Hsien Koh, Kean Lee Chew, Nadia Atiya, Nuntra Suwantarat, Rukumani Devi Velayuthan, Joshua Guo Xian Wong, and David C. Lye

Subjects
Medicine, Science
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Published
2021
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