1. Prevalence, clinical characteristics, and long-term outcomes of new diabetes diagnosis in elderly patients undergoing percutaneous coronary intervention
- Author
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Zheng-Kai Xue, Xin-Ya Dai, Jia-Yi Ren, Tong Liu, Yu-Kun Zhang, Su-Tao Hu, Peng Wang, Xue Wu, Jing-Kun Zhang, Gary Tse, Soohyung Park, Cheol-Ung Choi, Byoung-Geol Choi, Seung-Woon Rha, and Kang-Yin Chen
- Subjects
Newly diagnosed diabetes ,Elderly ,Coronary artery disease ,Percutaneous coronary intervention ,Medicine ,Science - Abstract
Abstract Previous studies have reported associations between newly diagnosed diabetes and poor outcomes after percutaneous coronary intervention (PCI), but there is limited data focusing on elderly patients (age ≥ 65). This study aimed to analyze the prevalence and clinical implications of newly diagnosed diabetes in elderly patients who underwent PCI. From 2004 to 2021, a total of 2456 elderly patients who underwent invasive PCI at Korea University Guro Hospital were prospectively enrolled and followed up for a median of five years. The primary endpoint was five-year major adverse cardiovascular events (MACE). Cox regression was used to evaluate whether newly diagnosed diabetes impacted on long-term clinical outcomes. Newly diagnosed diabetes was presented in approximately 8.1% to 10.9% of elderly patients who underwent PCI. Those who had a new diagnosis of diabetes had a higher risk of MACE than previously known diabetes (25.28% vs. 19.15%, p = 0.039). After adjusting for significant factors, newly diagnosed diabetes remained an independent predictor of MACE (HR [hazard ratio] 1.64, 95% confidence interval [CI] 1.24–2.17, p
- Published
- 2024
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