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1. Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis

Author

Wenjie Bao, Huayue Xing, Shiwei Cao, Xin Long, Haifeng Liu, Junwei Ma, Fan Guo, Zimu Deng, and Xiaolong Liu

Subjects
Science
Abstract

Disseminated intravascular coagulation is associated with sepsis and a number of inflammatory components have been linked to sepsis associated coagulopathy. Here the authors show neutrophils can prevent lethal coagulopathy via the production of extracellular vesicles that carry superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis.

Published
2022
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