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Your search keyword '"Trapani, JA"' showing total 15 results

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15 results on '"Trapani, JA"'

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1. Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing.

2. Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models.

3. Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance.

4. Antigen-driven EGR2 expression is required for exhausted CD8 + T cell stability and maintenance.

5. Lipid order and charge protect killer T cells from accidental death.

6. Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis.

7. Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.

8. Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.

9. Real-time visualization of perforin nanopore assembly.

10. Perforin and granzymes: function, dysfunction and human pathology.

11. NK cell intrinsic regulation of MIP-1α by granzyme M.

12. Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.

13. Endolysosomal proteases and their inhibitors in immunity.

14. Perforin-mediated target-cell death and immune homeostasis.

15. Functional significance of the perforin/granzyme cell death pathway.

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