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Your search keyword '"Amino acid sequence -- Research"' showing total 73 results
Start Over Descriptor "Amino acid sequence -- Research" Publisher nature publishing group
73 results on '"Amino acid sequence -- Research"'

1. Role of SUPERMAN in maintaining Arabidopsis floral whorl boundaries

Author

Sakai, Hajime, Medrano, Leonard J., and Meyerowitz, Elliot M.

Subjects
Arabidopsis -- Genetic aspects, Cloning -- Research, Amino acid sequence -- Research, Genetic regulation -- Research, Flowers -- Growth, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The SUPERMAN (SUP) gene is expressed in the third whorl of developing Arabidopsis flower and creates a boundary between the stamen and carpel whorls. The B function genes are positive regulators of the SUP gene. The SUP gene and AP3/PI act against each other. The SUP protein is required for transcriptional regulation and cellular proliferation. Sequence analysis of the SUP protein detects the presence of one zinc-finger and s region similar to the basic leucine zipper motif.

Published
1995

2. Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

Author

Reiner, Orly, Carrozzo, Romeo, Ying Shen, Wehnert, Manfred, Faustinella, Fabrizia, Dobyns, William B., Caskey, C. Thomas, and Ledbetter, David H.

Subjects
Brain -- Abnormalities, G proteins -- Genetic aspects, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

A gene which is absent in Miller-Dieker syndrome patients, who suffer from lissencephaly which is a brain malformation, has been cloned and LIS-1 has been found as the disease gene. Considerable homology to beta-subunits of heterotrimetic G proteins can be inferred from amino-acid sequences. The LIS-1 protein, which has eight WD 40 repeats of the same type, was found in G protein beta-subunits. LIS-1 may be crucial for brain development and could also be a part of a larger group of proteins which have the WD 40 repeat units in common.

Published
1993

3. How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme

Author

Heinz, Dirk W., Baase, Walter A., Dahlquist, Frederick W., and Matthews, Brian W.

Subjects
Amino acid sequence -- Research, Insertion elements, DNA -- Methods, Lysozyme -- Research, Molecular genetics -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

T4 lysozyme allows amino-acid insertions either by accommodation within the helix or by a looping out of its first or last turn. If the insertion is accommodated within the helix, then residues are translocated to the preceding loop. Insertions resulting in looping out within the helix are more destabilizing than those causing translocation. Which structural response follows a given insertion seems to depend on the relation between the helix and the remainder of the protein.

Published
1993

4. Protein folding in the cell

Author

Gething, Mary-Jane and Sambrook, Joseph

Subjects
Protein folding -- Research, Amino acid sequence -- Research, Cells -- Motility, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1992

7. Structure and functional properties of human general transcription factor IIE

Author

Peterson, Michael Gregory, Inostroza, Juan, Maxon, Mary E., Flores, Osvaldo, Admon, Arie, Reinberg, Danny, and Tjian, Robert

Subjects
Genetic transcription -- Research, RNA polymerases -- Research, Amino acid sequence -- Research, Antisense DNA -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

8. A primary determinant for lipoxygenase positional specificity

Author

Sloane, David L., Leung, Regina, Craik, Charles S., and Sigal, Elliott

Subjects
Protein binding -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

9. Molecular cloning and characterization of the rat NMDA receptor

Author

Moriyoshi, Koki, Masu, Masayuki, Ishii, Takahiro, Shigemoto, Ryuichi, Mizuno, Noboru, and Nakanishi, Shigetada

Subjects
Amino acid sequence -- Research, Central nervous system -- Genetic aspects, Cloning -- Research, Methyl aspartate, Antisense DNA -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

10. Sequence analysis of peptides bound to MHC class II molecules

Author

Rudensky, Alexander Yu, Preston-Hurlburt, Paula, Hong, Soon-Cheol, Barlow, Avlin, and Janeway, Charles A., Jr.

Subjects
Amino acid sequence -- Research, Immune recognition -- Research, Major histocompatibility complex -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

11. Identification of self peptides bound to purified HLA-B27

Author

Jardetzky, T.S., Lane, W.S., Robinson, R.A., Madden, D.R., and Wiley, D.C.

Subjects
Amino acid sequence -- Research, Binding sites (Biochemistry) -- Research, Antigens -- Research, Major histocompatibility complex -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

15. Multiple nucleotide-binding sites in the sequence of dynein beta heavy chain

Author

Gibbons, I.R., Gibbons, Barbara H., Mocz, Gabor, and Asai, David J.

Subjects
Nucleotide sequence -- Research, Amino acid sequence -- Research, Dynein -- Research, Binding sites (Biochemistry) -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

17. Primary structure and functional expression from complementary DNA of a brain calcium channel

Author

Mori, Yasuo, Friedrich, Thomas, Kim, Man-Suk, Mikami, Atsushi, Nakai, Junichi, Ruth, Peter, Bosse, Eve, Hofmann, Franz, Flockerzi, Veit, Furuichi, Teiichi, Mikoshiba, Katsuhiko, Imoto, Keiji, Tanabe, Tsutomu, and Numa, Shosaku

Subjects
Purkinje cells -- Research, Gene expression -- Research, Dihydropyridine -- Research, Amino acid sequence -- Research, Antisense DNA -- Research, Calcium channels -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

18. Base sequence discrimination by zinc-finger DNA-binding domains

Author

Nardelli, Jeannette, Gibson, Toby J., Vesque, Christine, and Charnay, Patrick

Subjects
Amino acid sequence -- Research, DNA binding proteins -- Research, Zinc in the body -- Physiological aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

21. A sodium-potassium switch in the formation of four-stranded G4-DNA

Author

Sen, Dipankar and Gilbert, Walter

Subjects
Sodium in the body -- Genetic aspects, Telomeres -- Genetic aspects, Stoichiometry -- Research, Cations -- Physiological aspects, Amino acid sequence -- Research, Potassium in the body -- Genetic aspects, G proteins -- Genetic aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

22. DNA cleavage catalysed by the ribozyme from Tetrahymena

Author

Herschlag, Daniel and Cech, Thomas

Subjects
Amino acid sequence -- Research, Bacterial genetics -- Research, Catalytic RNA -- Research, DNA -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

23. Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs

Author

Sakane, Fumio, Yamada, Keiko, Kanoh, Hideo, Yokoyama, Chieko, and Tanabe, Tadashi

Subjects
Phosphatidylinositol -- Research, Adenosine triphosphate -- Research, Protein binding -- Research, Phosphatases -- Research, Protein kinases -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

24. Rapid evolution of the sex determining locus in Old World mice and rats

Author

Tucker, P.K. and Lundrigan, B.L.

Subjects
Y chromosome -- Genetic aspects, Amino acid sequence -- Research, Genetically modified animals -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

A study of the pattern of the Y chromosome-linked sex determining locus (Sry) in Old World mice and rats revealed the usual rate of synonymous substitution, which was particularly true of the C-terminal region. Sry, and particularly the C-terminal region, is passing through speedy separation in the amino acid sequence. A transgenic approach can be used to follow the evolutionary importance of the amino-acid sequence divergence in Sry to find how variants of a gene of one species act in a related species.

Published
1993

25. Substitution of three amino acid switches receptor specificity of Gqalpha to that of Gialpha

Author

Conklin, Bruce R., Farfel, Zvi, Lustig, Kevin D., Julius, David, and Bourne, Henry R.

Subjects
Lectins -- Structure-activity relationships, G proteins -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The hypothesis that the ability of G proteins to differentiate among specific receptor subsets is determined by certain amino-acid residues located at the alpha-subunit C-termini is tested. Alphaq/alpha12 chimaeras mediating phospholipase C stimulation by receptors otherwise coupled to Gi were produced by substituting alphai2 residues for alphaq C-terminal acids. Results revealed that three alphai2 amino acids are were enought to cause a switch in the chimaeras' receptor specificity. This suggests that a C-terminal turn centered on a glycine three-residues away from the C-terminus has a significant role in the specification of receptor interactions of G proteins belonging to the Gi/Go/Gz family.

Published
1993

27. The second class story

Author

Germain, Ronald N.

Subjects
Immune recognition -- Research, Major histocompatibility complex -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

29. A new human HLA class II-related locus, DM

Author

Kelly, Adrian P., Monaco, John J., Cho, Sungae, and Trowsdale, John

Subjects
Immunoglobulins -- Research, Amino acid sequence -- Research, HLA class II antigens -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

31. Coelacanth's relationships

Author

Stock, David W., Swofford, David L., Sharp, Paul M., Lloyd, Andrew T., Higgins, Desmond G., Meyer, Axel, and Wilson, Allan C.

Subjects
Coelacanth -- Genetic aspects, Phylogeny -- Research, Amino acid sequence -- Research, Vertebrates -- Genetic aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

32. Editing of a chloroplast mRNA by creation of an initiation codon

Author

Hoch, Brigitte, Maier, Rainer M., Appel, Kurt, Igloi, Gabor L., and Kossel, Hans

Subjects
Codon -- Research, Amino acid sequence -- Research, Messenger RNA -- Research, Chloroplasts -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

33. Four ATP-binding sites in the midregion of the beta heavy chain of dynein

Author

Ogawa, Kazuo

Subjects
Binding sites (Biochemistry) -- Research, Amino acid sequence -- Research, Dynein -- Research, Adenosine triphosphate -- Research, Nucleotide sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1991

36. 16S rRNA sequences reveal numerous uncultured microorganisms in a natural community

Author

Ward, David M., Weller, Roland, and Bateson, Mary M.

Subjects
Yellowstone National Park -- Environmental aspects, Cyanobacteria -- Genetic aspects, Microbial ecology -- Research, Hot springs -- Environmental aspects, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

37. Chloropast DNA sequence from a Miocene Magnolia species

Author

Golenberg, Edward M., Giannasi, David E., Clegg, Michael T., Smiley, Charles J., Durbin, Mary, Henderson, David, and Zurawski, Gerard

Subjects
Plants, Fossil -- Genetic aspects, Paleobotany -- Miocene, DNA -- Research, Amino acid sequence -- Research, Magnolia -- Genetic aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

38. Relative helix-forming tendencies on nonpolar amino acids

Author

Padmanabhan, S., Marqusee, Susan, Ridgeway, Theresa, Laue, Thomas M., and Baldwin, Robert L.

Subjects
Amino acids -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

39. Stable expression of the bacterial neo r gene in Leishmania enriettii

Author

Laban, Avraham, Tobin, James Finbarr, Curotto de Lafaille, Maria A., and Wirth, Dyann F.

Subjects
Trypanosomatidae -- Genetic aspects, Messenger RNA -- Research, Leishmaniasis -- Genetic aspects, Neomycin -- Genetic aspects, Amino acid sequence -- Research, Parasites -- Genetic aspects, Protozoa -- Genetic aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1990

40. In search of rare human variants: the 1000 Genomes Project has completed its pilot phase, sequencing the whole genomes of 179 individuals and characterizing all the protein-coding sequences of many others. Welcome to the third phase of human genomics

Author

Nielsen, Rasmus

Subjects
Genetic research, Genetic variation -- Research, Human genome -- Research, Amino acid sequence -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The goal of the 1000 Genomes Project (1) is to find most of the variants in the human genome that have a frequency of at least 1% in the populations [...]

Published
2010

41. Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

Author

Kaupp, U. Benjamin, Niidome, Tetsuhiro, Tanabe, Tsutomu, Terada, Shoichi, Bonigk, Wolfgang, Stuhmer, Walter, Cook, Neil J., Kangawa, Kenji, Matsuo, Hisayuki, Hirose, Tadaaki, Miyata, Takashi, and Numa, Shosaku

Subjects
Gene expression -- Research, Cloning -- Research, Amino acid sequence -- Research, Photoreceptors -- Research, Cyclic guanylic acid -- Research, Antisense DNA -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1989

43. RNA editing in plant mitochondria

Author

Covello, Patrick S. and Gray, Michael W.

Subjects
RNA splicing -- Research, Amino acid sequence -- Research, Plant mitochondria -- Genetic aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1989

47. A highly conserved amino-acid sequence in thrombospondin, properdin, and in proteins from sporozoites and blood stages of a human malaria parasite

Author

Robson, Kathryn J.H., Hall, Jennifer R.S., Jennings, M.W., Harris, T.J.R., Marsh, K., Newbold, C.I., Tate, Valerie E., and Weatherall, D.J.

Subjects
Protein research -- Research, Amino acid sequence -- Research, Glycoproteins -- Research, Plasmodium falciparum -- Research, Cellular recognition -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Published
1988

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