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Your search keyword '"Zeng, Fanyi"' showing total 6 results
Start Over Author "Zeng, Fanyi" Publisher nature publishing group
6 results on '"Zeng, Fanyi"'

1. iPS cells produce viable mice through tetraploid complementation

Author

Zhao, Xiao-yang, Li, Wei, Lv, Zhuo, Liu, Lei, Tong, Man, Hai, Tang, Hao, Jie, Guo, Chang-long, Ma, Qing-wen, Wang, Liu, Zeng, Fanyi, and Zhou, Qi

Subjects
Gene expression -- Research -- Physiological aspects -- Genetic aspects, Embryonic development -- Physiological aspects -- Genetic aspects -- Research, DNA binding proteins -- Physiological aspects -- Genetic aspects -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation, Physiological aspects, Genetic aspects, Research
Abstract

Since the initial description of induced pluripotent stem (iPS) cells created by forced expression of four transcription factors in mouse fibroblasts, the technique has been used to generate embryonic stem [...]

Published
2009

2. Long-term deregulated human hematopoiesis in goats transplanted in utero with BCR-ABL-transduced lin(-)CD34(+) cord blood cells.

Author

Zeng F, Huang SZ, Gong ZJ, Chen MJ, Baldwin DA, Hu W, Qian H, Yan JB, Wang J, Xiao YP, Chalandon Y, Ringrose A, Ren ZR, Eaves A, Eaves C, and Jiang X

Subjects
Animals, Fetal Blood cytology, Goats, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Transplantation, Heterologous, WT1 Proteins metabolism, Antigens, CD34 metabolism, Cord Blood Stem Cell Transplantation, Fusion Proteins, bcr-abl genetics, Hematopoiesis
Published
2013
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3. Claudin 6: a novel surface marker for characterizing mouse pluripotent stem cells.

Author

Wang L, Xue Y, Shen Y, Li W, Cheng Y, Yan X, Shi W, Wang J, Gong Z, Yang G, Guo C, Zhou Y, Wang X, Zhou Q, and Zeng F

Subjects
Animals, Cell Differentiation, Claudins genetics, Down-Regulation, Embryonic Stem Cells cytology, Embryonic Stem Cells metabolism, Gene Expression Profiling, Homeodomain Proteins metabolism, Mice, Nanog Homeobox Protein, Octamer Transcription Factor-3 metabolism, Pluripotent Stem Cells cytology, SOXB1 Transcription Factors metabolism, Claudins metabolism, Pluripotent Stem Cells metabolism
Published
2012
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4. Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis.

Author

Tong M, Lv Z, Liu L, Zhu H, Zheng QY, Zhao XY, Li W, Wu YB, Zhang HJ, Wu HJ, Li ZK, Zeng F, Wang L, Wang XJ, Sha JH, and Zhou Q

Subjects
Animals, Blood Glucose analysis, Embryo, Mammalian cytology, Embryo, Mammalian embryology, Embryo, Mammalian metabolism, Embryonic Development, Embryonic Stem Cells cytology, Embryonic Stem Cells metabolism, Female, Fibroblasts cytology, Gene Expression Profiling, Induced Pluripotent Stem Cells cytology, Induced Pluripotent Stem Cells metabolism, Male, Mice, Phenotype, Reproductive Techniques, Survival Rate, Tetraploidy, Cell Transformation, Neoplastic, Embryonic Stem Cells physiology, Induced Pluripotent Stem Cells physiology
Published
2011
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5. Efficient and rapid generation of induced pluripotent stem cells using an alternative culture medium.

Author

Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, Hao J, Guo CL, Wang X, Wang L, Zeng F, and Zhou Q

Subjects
Animals, Cellular Reprogramming, Green Fluorescent Proteins genetics, Green Fluorescent Proteins metabolism, Humans, Mice, Octamer Transcription Factor-3 genetics, Octamer Transcription Factor-3 metabolism, Culture Media pharmacology, Induced Pluripotent Stem Cells cytology
Published
2010
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6. Establishment of customized mouse stem cell lines by sequential nuclear transfer.

Author

Zhao C, Yao R, Hao J, Ding C, Fan Y, Dai X, Li W, Hai T, Liu Z, Yu Y, Wang Y, Hou X, Ji W, Zhou Q, Jouneau A, Zeng F, and Wang L

Subjects
Animals, Cloning, Organism, Embryonic Stem Cells physiology, Female, Mice, Mice, Inbred C57BL, Mice, Inbred DBA, Cell Line, Cell Nucleus physiology, Embryonic Stem Cells cytology, Nuclear Transfer Techniques
Abstract

Therapeutic cloning, whereby embryonic stem cells (ESCs) are derived from nuclear transfer (NT) embryos, may play a major role in the new era of regenerative medicine. In this study we established forty nuclear transfer-ESC (NT-ESC) lines that were derived from NT embryos of different donor cell types or passages. We found that NT-ESCs were capable of forming embryoid bodies. In addition, NT-ESCs expressed pluripotency stem cell markers in vitro and could differentiate into embryonic tissues in vivo. NT embryos from early passage R1 donor cells were able to form full term developed pups, whereas those from late passage R1 ES donor cells lost the potential for reprogramming that is essential for live birth. We subsequently established sequential NT-R1-ESC lines that were developed from NT blastocyst of late passage R1 ESC donors. However, these NT-R1-ESC lines, when used as nuclear transfer donors at their early passages, failed to result in live pups. This indicates that the therapeutic cloning process using sequential NT-ESCs may not rescue the developmental deficiencies that resided in previous donor generations.

Published
2007
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