1. H19 and IGF-2 allele-specific expression in hepatoblastoma.
- Author
-
Ross JA, Radloff GA, and Davies SM
- Subjects
- Base Sequence, Child, Child, Preschool, DNA Primers, Female, Humans, Infant, Infant, Newborn, Male, RNA, Long Noncoding, Alleles, Hepatoblastoma genetics, Insulin-Like Growth Factor II genetics, Liver Neoplasms genetics, Muscle Proteins genetics, RNA, Untranslated
- Abstract
Patterns of allele-specific expression of H19 and insulin-like growth factor-2 (IGF-2) were examined in tissue obtained from 30 children diagnosed with hepatoblastoma. All informative tumours demonstrated monoallelic expression of H19. In contrast, variable patterns of allele-specific expression of IGF-2 were seen in tumours from children of different ages.
- Published
- 2000
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