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4 results on '"Bunthen E"'

2. Intermediate hepatitis B virus infection prevalence among 1622 pregnant women in rural Burkina Faso and implications for mother-to-child transmission

Author

Ouoba, Serge, Ko, Ko, Lingani, Moussa, Nagashima, Shintaro, Guingané, Alice N., Bunthen, E., Hussain, Md Razeen Ashraf, Sugiyama, Aya, Akita, Tomoyuki, Ohisa, Masayuki, Sanou, Moussa Abdel, Traore, Ousmane, Nassa, Job Wilfried, Sanou, Maimouna, Takahashi, Kazuaki, Tinto, Halidou, and Tanaka, Junko

Published
2023
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4. Prevalence of total hepatitis A antibody among 5 to 7 years old children and their mothers in Cambodia

Author

Junko Tanaka, Shafiqul Hossain, Channarena Chuon, Serge Ouoba, Chikako Yamamoto, Bunthen E, Vichit Ork, Tomoyuki Akita, Shintaro Nagashima, Ko Ko, Bunsoth Mao, Aya Sugiyama, and Masayuki Ohisa

Subjects
0301 basic medicine, Male, Disease prevention, Sanitation, Viral epidemiology, Science, media_common.quotation_subject, Hepatitis A Antibodies, Article, 03 medical and health sciences, 0302 clinical medicine, Hygiene, Seroepidemiologic Studies, Food supply, Environmental health, parasitic diseases, Prevalence, Medicine, Humans, 030212 general & internal medicine, Dried blood, Child, Whole blood, media_common, Public health, Multidisciplinary, Hepatology, business.industry, virus diseases, Gold standard (test), Hepatitis A, Hepatitis A antibody, 030104 developmental biology, Concomitant, Child, Preschool, Infectious diseases, Female, business, Cambodia, Hepatitis A Virus, Human
Abstract

This study determined the prevalence of total hepatitis A antibody (anti-HAV) among 5–7 years old children and their mothers in the whole Cambodia, using a nationwide study, and examined the differences between the two cohorts. A total of 4535 dried blood spot-driven (DBS) samples (2021 mothers and their 2514 children of 5–7 years old) and the concomitant 922 whole blood samples (subset of the whole participants) were collected using a multistage random sampling strategy throughout Cambodia in 2017. Total anti-HAV was detected using the chemiluminescence enzyme immunoassay method. Compared to gold standard whole blood samples, the sensitivity and specificity of DBS mediated anti-HAV detection were 94.8% and 98%, respectively. Total anti-HAV prevalence among mothers was 91.2% (95%CI: 90.0–92.5%), and that of their children was 31.5% (95%CI: 29.7–33.3%). In our study, the low prevalence of total anti-HAV among children indicates the country’s improvement of safe water and food supply, hygiene and sanitation. If the hygiene and sanitation are consistently improved in Cambodia, the prevalence might be no longer increased when the children become adults.

Published
2021

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