1. [The 1st case of adult T-cell leukemia (ATL) with expressed immune response to HTLV in the USSR].
- Author
-
Gurtsevich VE, Seniuta NB, Pivnik AV, Pavlish OA, Stepina VN, Syrtsev AV, Iakhnina EI, and Kremenetskaia AM
- Subjects
- Gene Expression Regulation, Viral, Gene Products, gag analysis, HTLV-I Antibodies genetics, Humans, Immunoblotting, Leukemia-Lymphoma, Adult T-Cell immunology, Male, Middle Aged, USSR epidemiology, HTLV-I Antibodies analysis, Human T-lymphotropic virus 1 genetics, Human T-lymphotropic virus 1 immunology, Leukemia-Lymphoma, Adult T-Cell epidemiology
- Abstract
The first of case of adult T-cell prolymphocytic lymphosarcoma is reported which according to the natural course, cell composition of tumor, cell surface markers as well as expressed immune response to a wide spectrum of HTLV-1 gag an env encoded proteins can be classified as HTLV-associated adult T-cell leukemia. Diagnosis of the tumor alongside with identification of HTLV-1-infected individuals in the USSR emphasizes the need to stimulate research in HTLV-1-associated carcinogenesis in this country.
- Published
- 1991