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1. [Histomorphological study of mice inbred CBA liver under combined chronic influence of low dose gamma radiation and incorporated thorium nitrate].

Author

Gur'ev DV and Materiĭ LD

Subjects
Animals, Cell Division radiation effects, Cell Nucleus pathology, Cell Nucleus radiation effects, Dose-Response Relationship, Radiation, Liver radiation effects, Liver Regeneration radiation effects, Male, Mice, Mice, Inbred CBA, Radiation Injuries, Experimental etiology, Soil Pollutants, Radioactive toxicity, Thorium Compounds toxicity, Gamma Rays adverse effects, Liver pathology, Radiation Injuries, Experimental pathology, Soil Pollutants, Radioactive administration & dosage, Thorium Compounds administration & dosage
Abstract

We studied histomorphology of the CBA line mice liver after 30 and 90 days of the low dose gamma-radiation influence combined with incorporated Th(NO3)4 in doses 0.03; 0.1; 0.3 grams per kilogram of the living mouse weight. Morphophysiological and morphometric changes were shown. The liver mass and index were significant by increased after 30 days influence. The same changes after 90 days influence were not shown. The morphometric parameters (dynamics of double-nucleus and polyploid hepatocytes, nucleoluses numbers) gave evidence of the liver energy disbalance.

Published
2000

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