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A patent application by inventor Peter Forsell for a knee joint device and method has been made available online. The device is designed for implantation in a human knee joint and consists of two parts that connect to form an assembled medical device with a curved outer surface. The device aims to address issues related to knee joint osteoarthritis and improve the stability of the artificial knee joint surface. The method for implanting the device involves connecting the parts to clasp a portion of the knee joint bone and may include the use of fixation elements and bone cement. [Extracted from the article]

A recent study conducted at Imperial College London focused on the role of repeat postoperative radiographs in predicting revision surgery following primary knee arthroplasty using machine learning. The study analyzed data from adult patients undergoing primary knee arthroplasty at Imperial NHS Trust over a five-year period. The research found that X-ray frequency can independently predict revision surgery, with each additional X-ray increasing the revision risk by 52%. The study suggests that these insights can guide evidence-based post-operative decision-making and improve risk stratification for patients at higher revision surgery risk. [Extracted from the article]

Researchers at New York University Grossman School of Medicine have developed a model using self-supervised deep learning to estimate the time-to-total knee replacement (TKR) by analyzing radiographs and MRI scans. The model integrates features from medical images, clinical measurements, and image assessments to predict when surgery may be needed with high accuracy. This approach could assist physicians in developing personalized treatment strategies for patients. The study highlights the potential of multi-modal data fusion and self-supervised learning in improving predictions for TKR. [Extracted from the article]

Researchers at the First Hospital of Hebei Medical University conducted a study on the effects of continuous nursing intervention on patients undergoing unicondylar knee replacement. The study included 90 participants and found that those who received continuous nursing intervention showed significant improvements in knee joint function, quality of life, and treatment satisfaction compared to those who did not. The research concluded that early postoperative rehabilitation guidance and regular reviews lead to better outcomes and improved quality of life for patients undergoing unicondylar knee replacement. [Extracted from the article]

Encore Medical L.P. has been issued a patent for partial knee implants and methods for installing them, aiming to improve upon current knee implant designs and installation techniques. The patent focuses on Unicompartmental-knee arthroplasty (UKA), a procedure that replaces only one compartment of the knee, preserving healthy parts of the knee affected by arthritis. The patent details a surgical approach for installing these implants, emphasizing the importance of proper patient selection and surgical techniques for successful outcomes. The potential benefits of UKA include smaller incisions, less post-operative pain, quicker recovery, improved range of motion, reduced blood loss, shorter hospital stays, and decreased costs. [Extracted from the article]

A recent report from China University of Mining and Technology examines the wear mechanism and debris analysis of PEEK as an alternative to CoCrMo in the femoral component of total knee replacement. The study found that the wear loss of XLPE in PEEK-XLPE knee prosthesis was lower than that of XLPE in CoCrMo-XLPE after 5 million cycles of in vitro wear. The research concluded that the wear mechanism of PEEK is abrasive wear and adhesion, while that of CoCrMo is abrasive wear and corrosion. [Extracted from the article]

A recent study from the University of York in the United Kingdom examined the effectiveness of combining adductor canal blocks (ACB) with local infiltration analgesia (LIA) for pain control post total knee replacement surgery. The study found that patients who received the combination of ACB and LIA had lower pain scores, used less morphine, and had better range of motion compared to those who received either treatment alone. However, the researchers concluded that more randomized controlled trials are needed to confirm the superiority of the combination therapy. The study was published in BMJ Open and can be accessed for free online. [Extracted from the article]

A recent study conducted at State University Campinas in Brazil aimed to provide a comprehensive functional characterization of patients with severe knee osteoarthritis who require total knee replacement surgery. The research focused on identifying objective criteria to determine the need for surgery, as the lack of such criteria can lead to patient dissatisfaction. The study analyzed various functional parameters, including quadriceps strength and performance in the 6-minute walk test, to correlate with the severity of knee osteoarthritis. The findings may assist orthopedic surgeons in making informed decisions regarding total knee replacement for patients with severe knee osteoarthritis. [Extracted from the article]

Researchers from Kyushu University conducted a study on knee replacement surgery, focusing on the alignment of the knee joint. They found that preserving the patient's original alignment during surgery led to better long-term outcomes. The study utilized a classification system called the Coronal Plane Alignment of the Knee (CPAK) to categorize knee alignments and determine the impact on patient-reported outcomes. The researchers emphasized the importance of replicating a patient's native alignment for optimal recovery and quality of life post-surgery, suggesting that this approach could become a new standard in orthopedic surgery. [Extracted from the article]

A patent application titled "Total Knee Revision Arthroplasty Implant Kit" by inventor Carlos E. Collazo has been published online by the USPTO. The application, assigned to Howmedica Osteonics Corp., focuses on addressing challenges in knee revision surgery, particularly related to bone loss and implant stability. The invention involves a joint replacement assembly with unique features to improve fixation and stability, offering potential advancements in the field of orthopedic procedures and surgical technology. [Extracted from the article]

The article discusses a clinical trial, NCT06670651, focusing on the LinkSymphoKnee total knee replacement system with an ultra-congruent tibial bearing surface. The trial aims to collect data on implant performance and patient outcomes in primary total knee arthroplasty. The study will involve up to 600 patients from three sites, evaluating various outcome measures such as KOOS-JR, Knee Society Score, PROMIS Global Health, and radiographic findings over a period of up to five years postoperatively. The trial is observational in nature and is not yet recruiting participants, with a completion date set for December 31, 2031. [Extracted from the article]

A patent has been issued for methods and devices designed to support a patient's leg during recovery from medical procedures, such as total knee replacements. The inventions aim to increase comfort and improve sleep quality for patients, potentially reducing the need for narcotic pain medication post-surgery. The devices are adjustable, accommodating patients of different sizes, and can counteract the natural tendency of legs to rotate outward, aiding in recovery and rehabilitation. The patent, assigned to DLA Medical LLC, outlines specific features and methods for utilizing the devices to assist patients in their recovery process. [Extracted from the article]

Researchers from the Government College of Engineering in Dharmapuri, India, have developed a Modified Elman Recurrent Neural Network (MERNN) model for thigh muscle segmentation in patients undergoing Total Knee Replacement (TKR). The MERNN model utilizes MRI images and optimization techniques to accurately quantify muscle volume, achieving a 98.5% accuracy rate. This study aims to improve the outcomes of TKR procedures by providing a more precise and tailored fit for prosthetic devices. The research has been peer-reviewed and published in the Iranian Journal of Science and Technology Transactions of Electrical Engineering. [Extracted from the article]

A patent has been issued for a modular total knee arthroplasty system and method by Arthrology Consulting LLC. The invention aims to simplify knee replacement surgery processes, making them less time-consuming. The system includes modular trial implant assemblies and kits for total knee arthroplasty, providing options for primary and revision knee replacements. The patent outlines methods for installing knee implant assemblies using straight reamers and tapered cone reamers, offering innovative solutions for knee replacement surgeries. [Extracted from the article]

A clinical trial, NCT06651762, is exploring the use of ultrasound-guided genicular nerves cooled radiofrequency ablation in total knee replacement surgeries to manage post-operative pain. The trial aims to improve patient rehabilitation, hospital stay, and satisfaction by reducing pain levels. The study is being conducted at Ain Shams University in Egypt and is currently recruiting participants. [Extracted from the article]

A recent study conducted by Technical University Berlin (TU Berlin) examined the cost-effectiveness of a patient-reported outcome-based remote monitoring and alert intervention for early detection of critical recovery paths following hip and knee replacement surgeries. The study, which included 3,697 patients with hip replacement and 3,110 patients with knee replacement, found that the intervention group showed improved patient outcomes at lower costs compared to standard care, particularly in patients with hip replacements. The research suggests that patient-reported outcome measures (PROMs) can be a cost-effective tool for remote monitoring in standard care settings. [Extracted from the article]

Researchers have submitted a patent application for a new method called "Knee Joint Method" aimed at improving knee replacement surgery for patients suffering from knee joint osteoarthritis. The method involves implanting a medical device with specific inner and outer surface features to replace damaged knee joint components. This innovative approach seeks to address issues related to cartilage failure, inflammation, and pain associated with knee joint conditions. The patent application was filed by inventor Peter Forsell and is currently pending approval. [Extracted from the article]

A study conducted at Inner Mongolia University of Science and Technology explored the effects of 60 degrees of knee flexion combined with perioperative use of tranexamic acid on the recovery of knee replacement patients. The research found that this combination significantly reduced blood loss, increased red blood cells, hemoglobin levels, and red blood cell volume on postoperative days 1 and 3, and reduced swelling of the affected limb. The study concluded that this approach can improve postoperative outcomes for patients undergoing knee replacement surgery. [Extracted from the article]

Researchers from the Department of Orthopedic Surgery in Antwerp, Belgium, conducted a study on the functional outcomes of bicompartmental knee arthroplasty (BKA) for medial and patellofemoral osteoarthritis. The study focused on pain alleviation, knee function, patient-reported outcome measurements, range of motion, radiographic alignment, implant survivorship, adverse events, and length of stay. Results showed promising improvements in pain relief and knee function, with challenges including the risk of revision and technical difficulties during surgery. Further research, particularly randomized trials with larger cohorts, is needed to understand the long-term benefits and drawbacks of BKA compared to other knee arthroplasty options. [Extracted from the article]

The article discusses a clinical trial, NCT06627673, focusing on the performance of the Maxx Orthopedics, Freedom Total Knee(R) System with a polyether-ether-ketone (PEEK) femoral component. The study aims to determine the safety and efficacy of the PEEK-OPTIMA(TM) femoral component compared to a CoCr alloy femoral component for Total Knee Arthroplasty (TKA). The trial involves 200 patients and will assess outcomes using various measures such as the Knee Society Score, KOOS-JR, PROMIS Global-10, VAS score, and Forgotten Joint Score. The study is not yet recruiting participants and is expected to be completed by March 1, 2028. [Extracted from the article]

A patent has been issued for devices, systems, and methods for monitoring knee replacements. Knee replacement surgery is a common procedure used to treat conditions such as osteoarthritis and rheumatoid arthritis. The patent describes the use of sensors placed on or within the knee prosthesis to monitor its integrity and effectiveness. These sensors can be positioned on the outer or inner surfaces of the prosthesis, within the materials used to construct it, or within the surrounding tissues. The sensors can measure factors such as acceleration, rotation, pressure, and contact, providing valuable information about the function and performance of the knee replacement. The patent also mentions the use of wireless sensors and sensors connected to wireless microprocessors. This technology allows for continuous monitoring of the patient's activity, prosthesis function, and potential side effects. The patent includes specific claims for a tibial component with sensors, as well as a monitoring system that includes a tibial plate, tibial liner, and various sensors. The patent was filed by William L. Hunter and is assigned to Canary Medical Inc. [Extracted from the article]

A preprint abstract from medrxiv.org discusses a novel deep learning framework called Gait-to-Contact (G2C) that aims to predict wear in total knee replacement (TKR) surgeries. The study introduces a deep learning model that significantly reduces computational costs and processing time compared to traditional finite element analysis (FEA) models. The deep learning model was trained to predict wear distribution using gait pattern time series as input and yielded promising results, with computational time reduced to minutes compared to days for FEA models. The study suggests that this approach could lead to more personalized and timely interventions in TKR settings. However, it is important to note that this preprint has not been peer-reviewed. [Extracted from the article]

This document provides information about a clinical trial for knee osteoarthritis. The trial is currently recruiting participants and aims to compare two different surgical interventions for knee replacement. The study will enroll 95 participants and is expected to be completed by December 2028. The eligibility criteria include being between 21 and 79 years old and undergoing primary total knee arthroplasty with a specific knee system. The trial is being conducted in the United States and is sponsored by Medacta International SA. The principal investigator is Dr. Adam Edelstein from Northwestern University. The trial's NCT number is NCT06617871. [Extracted from the article]

This document provides information about a clinical study on total knee prostheses for patients with knee osteoarthritis. The study aims to evaluate the clinical and imaging results, biomechanics of the prosthetic knee during gait, and muscular strength of knee extension for two different types of prostheses. The study is still in the recruitment phase and plans to enroll 120 participants. The study is being conducted by the Clinique du Sport in Bordeaux Merignac. [Extracted from the article]

A patent application titled "Surgical Kit And Methods Of Forming The Same" has been published online by the US Patent and Trademark Office. The patent application, filed by inventors from Morgantown, West Virginia, describes a surgical kit that includes multiple trays containing preassembled surgical instruments made of disposable material. The trays are arranged in the order in which they are to be used during a surgical procedure, and the kit is wrapped in sterile material. The invention aims to improve surgical efficiency and reduce the risk of contamination by eliminating the need for instrument assembly during a procedure. The assignee for this patent application is NovoSource LLC. [Extracted from the article]

A patent application has been submitted for "Unicondylar Instruments and Procedures" to improve the accuracy of tibial and femoral cuts in unicondylar knee replacement surgeries. The application outlines various surgical instruments, kits, and methods for making these cuts. It includes a curved unicondylar posterior femoral cutting guide, a tibial reference guide, and a tibial jig for adjusting the tibial cut. Additionally, a unicondylar femoral cutting guide with a base, post, and member is described. The application also mentions a kit of surgical instruments that includes cutting guides and posts of different sizes for different-sized prosthetic implants. This document provides detailed information and diagrams for those interested in the technical aspects of unicondylar knee replacement procedures. [Extracted from the article]

A new study published in the Journal of Vascular and Interventional Radiology suggests that a minimally invasive treatment called genicular artery embolization (GAE) may provide lasting relief for patients with knee osteoarthritis (OA). The study followed 40 patients with moderate-to-severe symptomatic knee OA who were not candidates for knee replacement surgery. The results showed that GAE provided durable benefits for up to 2 years, with 47% of patients reporting a greater than 50% reduction in OA symptoms over the 2-year follow-up period. The procedure involves creating a small incision in the hip and injecting tiny particles to normalize blood supply to inflamed areas of the knee. Further research is needed to validate these findings and optimize the management of knee pain related to OA. [Extracted from the article]

The clinical trial NCT06611319, titled "ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty" (ENABLE-Hip), aims to determine the appropriate duration of postoperative anticoagulation for patients undergoing hip replacement surgery. The trial will compare a 10-day regimen of anticoagulation to the standard 35-day regimen using the drug Rivaroxaban. The primary outcome being measured is the occurrence of deep vein thrombosis or pulmonary embolism within 90 days after surgery. If the trial demonstrates the non-inferiority of the shorter duration of anticoagulation, it could potentially spare patients unnecessary and potentially harmful treatment. The study will involve a randomized, double-blind, active-control trial with a planned sample size of 2,932 patients. The results of this study have the potential to inform future guidelines for the prevention of venous thromboembolism in patients undergoing hip replacement surgery. [Extracted from the article]

A study conducted at the National Orthopaedic Hospital in Lagos, Nigeria, examined the effectiveness of intravenous tranexamic acid (TXA) in reducing blood loss during total hip and knee replacement surgeries. The study found that administering 1 gram of TXA significantly reduced intraoperative blood loss, postoperative blood loss, and total blood loss by 30%, 31%, and 25.8% respectively, compared to a placebo. The TXA group also experienced a significant reduction in hemoglobin drop and a lower need for blood transfusions. The researchers concluded that 1 gram of intravenous TXA is effective in reducing perioperative bleeding and the need for blood transfusions in total hip and knee replacement surgeries. [Extracted from the article]

This patent describes an invention related to the use of surface treatments and anisotropic materials in medical devices, specifically for repairing fractures in bones. The invention involves the use of asymmetrical surface treatments to aid in the installation and removal of implants. Additionally, the patent discusses the use of anisotropic materials with variable stiffness profiles that can be selectively degraded or absorbed during the healing process. The invention has applications in various medical devices, including external fixators, internal plates, and intramedullary rods. [Extracted from the article]

A patent has been issued for a universal femoral trial system and methods by Optimotion Implants LLC. The patent describes various knee replacement options depending on the condition of the knee anatomy, including the use of different knee prosthesis systems. The patent also discusses the challenges of replacing bone anchoring components and the ease of replacing tibial inserts. The patent includes details of an assembly for facilitating orthopedic surgery, which includes a body, a drill guide, and an attachment mechanism. The assembly is designed to secure the body to an external frame and includes tabs that can extend outward from the body. The patent also describes an assembly for preparing and trialing a bone to receive an implant, which can be removably coupled to a trial component. The patent provides detailed claims for the various assemblies described. [Extracted from the article]

Researchers from the University of York have highlighted the need for occupational support for patients undergoing hip or knee replacement surgery in the UK. Currently, one in four patients are in work at the time of their surgery but receive little support for their return to work. To address this, the researchers have developed the OPAL (Occupational support for Patients undergoing Arthroplasty of the Lower limb) intervention, which includes multimedia information resources and support from a designated return-to-work coordinator. The effectiveness of this intervention will be assessed in a multicenter, randomized controlled trial involving 742 working adults. The primary outcome will be the time until full sustained return to work without sick leave for a consecutive 4-week period. The trial aims to support the wider adoption and implementation of the intervention if it proves effective. [Extracted from the article]

A recent study conducted in the United Kingdom aimed to determine the feasibility of a prehabilitation program for frail patients undergoing hip or knee replacement surgery. The study involved 64 participants who were randomized to receive the intervention, which included a home-based exercise program and protein supplementation. The results showed that a larger study is possible, and improvements were identified to optimize the design of a randomized controlled trial. Overall, the trial processes and intervention were generally acceptable to participants, although areas for potential improvement were identified. [Extracted from the article]

A recent study conducted by researchers at the University of St Andrews focused on the challenges and strategies for cleaning routinely collected data on total knee replacements (TKR) and total hip replacements (THR) in the Kingdom of Fife. The researchers utilized data from NHS Fife, which included information on patient demographics, type of surgery, recovery time, follow-ups, revision, and outcomes. Using the programming language R, the researchers transformed the raw data into a more functional form, combining variables and converting purposeless values into missing data. The cleaned data can now be linked to other datasets and used for future machine learning models to assess the risk and outcomes of multiple knee and hip replacements. [Extracted from the article]

A new study conducted in Maharashtra, India, examined the use of preemptive analgesia (PA) in patients undergoing total knee replacement (TKR) surgeries. The study divided 105 patients into three groups, each receiving different analgesic treatments. The results showed that Group 2, which received a combination of medications including injection tramadol, had the lowest pain scores and required less medication post-surgery. Additionally, patients in Group 2 were able to mobilize earlier compared to the other groups. The study concluded that PA can reduce pain and inflammation after TKR surgeries, potentially leading to a decreased risk of chronic pain and aiding in early mobilization. [Extracted from the article]

A recent study conducted by researchers at Chung Shan Medical University in Taichung, Taiwan, explored the potential link between total knee replacement (TKR) surgery and an increased risk of developing thyroid diseases. The study analyzed electronic medical records from a large U.S. research network and found that TKR patients had a significantly higher risk of developing thyroid diseases compared to those who did not undergo the surgery. The elevated risk was particularly notable among older adults and females. The study suggests that healthcare providers should monitor and manage thyroid dysfunction in TKR patients, and further research is needed to understand the underlying mechanisms and develop preventive strategies. [Extracted from the article]

A patent application by inventor Michael David Daily describes methods and apparatus for attaching a patch to a user's exterior surface, specifically scar tissue, to facilitate manipulation of the scar tissue. The invention aims to address issues caused by scarring, such as limited tissue mobility and negative effects on circulation, muscle contractibility, and joint range of motion. The patch includes a base with an adhesive for attachment to the user's skin and a handle for movement. The invention may have applications in knee replacement surgery, which is performed approximately 800,000 times annually in the United States alone and often results in a significant scar on the front of the knee. [Extracted from the article]

A study conducted by researchers at Oxford University Hospitals NHS Foundation Trust explored the experiences of patients who underwent revision knee replacement surgery for aseptic, elective reasons. The study found that living with a problematic knee replacement and undergoing revision surgery had a significant impact on patients' lives. The findings highlight the need for patients to have access to care, assessment, and long-term psychological and rehabilitation support before and after revision surgery. The study provides valuable insights for healthcare professionals and patients dealing with knee replacement procedures. [Extracted from the article]

A recent study conducted by the Chinese University of Hong Kong compared the effectiveness of telerehabilitation with conventional in-person rehabilitation in patients who underwent total knee replacement surgery. The study found that telerehabilitation was comparable to conventional rehabilitation in improving pain and physical function outcomes. Additionally, telerehabilitation was found to be a more cost-effective alternative, with lower utilization of hospital resources and costs. This research provides evidence for the potential benefits of telerehabilitation in post-surgical knee replacement patients. [Extracted from the article]

The patent application by Robert J. Daley and Sean M. Daley describes a surgical procedure planning system that aims to improve surgical outcomes by addressing the variability and uncertainty in surgical procedures. The system utilizes aggregation techniques to provide feedback to preoperative plan creators, allowing them to optimize individual plans. It also incorporates measurements of distances from anatomical landmarks to generate operative plans based on specific patient characteristics. The system involves creating a virtual model of the surgical plan on a patient's anatomy, allowing for review and changes to be made. The system also allows for adjustments to the operative plan during the surgery based on new data collected. Feedback loops are used to improve future preoperative plans and models. [Extracted from the article]

A patent application has been filed for a surgical instrument system for total knee replacement. The system includes a sensor adapter with a force sensor and a sensor contact, as well as multiple surgical instruments with sensor connectors and registering features. The sensor adapter is designed to transfer force exerted on the sensor contact to the force sensor, and the surgical instruments are configured to engage anatomical features of the patient or other surgical instruments. This system aims to improve the accuracy and effectiveness of knee replacement surgeries by providing real-time feedback on ligament tension and joint force. [Extracted from the article]

Surgery Hero, a digital health company, has been awarded a research grant of £700,000 from the National Institute for Health and Care Research (NIHR). The grant will fund a three-year study to assess the effectiveness of Surgery Hero, a digital surgery clinic, in improving long-term outcomes for patients undergoing hip or knee replacement surgery. The study aims to provide insights into the potential of digital interventions to enhance recovery and quality of life for patients. Surgery Hero offers comprehensive support to patients, combining evidence-based guidance, personalized health coaching, and digital resources. The company believes that this trial will demonstrate the significant value of incorporating Surgery Hero into perioperative pathways and supporting patients through complex surgical journeys. [Extracted from the article]

The article focuses on a clinical trial investigating the necessity of elastic restraints in modern rehabilitation programs for hip and knee prosthetic surgery. Topics include evaluating the effectiveness of elastic compression devices, comparing pharmacological versus combined prophylaxis methods, and assessing thromboembolic event prevention.

A patent application titled "Prosthetic Implant Revision Tools" has been published online by the US Patent and Trademark Office. The patent application, filed by inventors Jose S. Rivera Jr., aims to provide tools that aid in the efficient removal of a prosthetic implant during revision surgeries. The tools are designed to minimize damage to surrounding bone and tissue, reduce bone loss, and improve the success of revision procedures. The patent application includes detailed descriptions and claims for the tools. The assignee for this patent application is Simplex Designs LLC. [Extracted from the article]

A recent study conducted at the University of Calgary in Canada examined the economic costs associated with surgical site infections (SSIs) and revisions following hip and knee arthroplasties. The study analyzed the cost of different revision procedures for complex SSIs in Alberta, Canada, using data from the Alberta Health Services Infection Prevention and Control database. The findings showed that the highest medical costs occurred within the first 12 months following the initial arthroplasty, and two-stage revision procedures were the most expensive. The study provides valuable insights into the economic burden of managing prosthetic joint infections in Alberta. [Extracted from the article]

Johns Hopkins University and Gigstride Corporation are conducting a clinical trial, NCT06548087, to evaluate the use of the Gigstride ambulatory device in patients with lower extremity deficits. The trial aims to assess patient satisfaction with the device and its effects on various aspects of mobility, such as kinetics, biomechanics, walking speed, stair speed, and stability. Participants will use the device for different tasks and complete a questionnaire to evaluate ease of use and comfort. The study is open to individuals of all sexes who have received treatment for a lower extremity mobility deficit and have provided written consent. The primary contact for the study is Akhil Chhatre, MD, and it is expected to be completed by September 2025. [Extracted from the article]