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Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have discovered a new group of bitter compounds in roasted Arabica coffee, shedding light on why coffee tastes more bitter to some individuals. They found that genetic predisposition also influences how bitter these compounds taste, with certain individuals being more sensitive to bitterness due to their genetic makeup. This research deepens our understanding of how the roasting process affects coffee flavor and may lead to the development of coffee varieties with specific taste profiles. [Extracted from the article]

A recent report from King Saud University in Riyadh, Saudi Arabia, discusses the impact of artificial sweeteners on health. The study suggests that artificial sweeteners like sucralose, saccharin, and aspartame may disrupt the gut microbiota, leading to glucose intolerance and metabolic disorders. The researchers emphasize the need for further research to better understand the health implications of sweetener consumption and make informed dietary choices. This research has been peer-reviewed and provides valuable insights into the potential risks associated with the use of low-calorie sweeteners. [Extracted from the article]

The article explores the impact of non-caloric sweeteners (NCS) combined with glucose on hypothalamic glucose sensing and insulin secretion in rats. The study suggests that the presence of NCS alongside glucose may lead to physiological effects, such as reduced insulin secretion and increased food intake. The research indicates that NCS interfere with mitochondrial signaling and energy production during hypothalamic glucose sensing. This preprint has not yet undergone peer review. [Extracted from the article]

The article discusses a patent issued to Mars Incorporated for screening methods using GPRC6A taste receptors in pet food products. The patent aims to identify compounds that enhance or modify the palatability of pet food products by enhancing taste, texture, and flavor profiles. The methods outlined in the patent focus on increasing the acceptance of pet medications and ensuring that pet food is both palatable and nutritious. The patent provides detailed steps for identifying compounds that modulate the activity of GPRC6A receptors in pet food products. [Extracted from the article]

Researchers from the Shibaura Institute of Technology in Saitama, Japan, conducted a study on the interaction between the human bitter taste receptor T2r46 and polyphenols using computational chemistry. The study found that polyphenols may act as ligands for T2r46, with specific amino acids playing a crucial role in the recognition of polyphenols. The research, supported by Grants-in-Aid for Scientific Research, highlights the potential regulatory effect of bitter taste receptors on gastrointestinal hormones. This study provides valuable insights into the relationship between polyphenols and T2r46, contributing to the field of gastroenterology and computational chemistry. [Extracted from the article]

The article discusses the process of taste cell renewal and death within taste buds, focusing on the role of glial-like Type I cells in engulfing dying taste receptor cells. The study utilized morphological data from murine circumvallate taste buds to identify dying cells exhibiting features of apoptosis, with Type I cells potentially playing a phagocytic role in engulfing these cells. The ultimate fate of Type I cells remains unknown, highlighting the complexity of taste cell dynamics. [Extracted from the article]

The article discusses how animals, specifically Drosophila larvae, use their taste system to detect bacterial peptidoglycans in their environment, which then primes their cellular immune response. The study shows that specific PeptidoGlycan Receptor Proteins (PGRPs) in bitter taste neurons activate the IMmune Deficiency (IMD) pathway, leading to immune cell production in the larval hematopoietic organ. This sensory-mediated immune response helps protect animals from bacterial infections and highlights the interconnectedness between the nervous and immune systems. The findings suggest that taste plays a crucial role in detecting and responding to potential pathogens, ultimately improving survival rates after infection in adult flies. [Extracted from the article]

A recent study led by researchers from The Hebrew University of Jerusalem discovered a hidden "pocket" within the human bitter taste receptor TAS2R14, shedding new light on how the receptor interacts with various compounds. This breakthrough could have implications for drug design, including potential treatments for asthma and inflammation. The study used advanced electron microscopy technology to reveal that some bitter molecules bind simultaneously at two distinct locations on the receptor, one outside the cell and the other inside it, providing new insights into how the receptor functions. Researchers believe that understanding these mechanisms could lead to the development of medications targeting bitter taste receptors to treat various conditions beyond taste perception. [Extracted from the article]

A study investigated the association between genetic variations in Bitter Taste Receptor genes and self-reported oral health outcomes in the Canadian Longitudinal Study on Aging. The analysis included 124 SNPs and 21,991 individuals of European ancestry, revealing that certain SNPs in TAS2R genes were significantly linked to sore jaw muscles, a symptom often associated with temporomandibular disorders. The study suggests that genetic screening of TAS2R genes could help identify individuals at higher risk for TMD, potentially leading to personalized treatment strategies and a better understanding of genetic risk factors for TMD. [Extracted from the article]

Researchers from the University of California Los Angeles (UCLA) have conducted a study on bitter taste receptors as sensors of gut luminal contents in the field of Life Science. The study highlights the role of taste receptors in gastrointestinal mucosa and their potential impact on metabolic disorders. Bitter taste receptors are found in various types of gastrointestinal mucosal cells and play a crucial role in regulating gut chemosensory processes, digestion, absorption of nutrients, and immune responses. This research, supported by the National Institutes of Health (NIH), provides new insights into the complex functions of taste receptors in the gut. [Extracted from the article]

Researchers have submitted a patent application for formulations and compositions designed for ortho- and/or retro-nasal delivery of substances to target receptors in the nose, mouth, and throat. These formulations aim to enhance the delivery of active substances for therapeutic and physiological responses, such as relieving congestion or modulating metabolic function. By utilizing aerosolized droplets with specific mass median sizes and concentrations of agonists or antagonists, these methods offer a novel approach to delivering spices, nutrients, and therapeutic substances with increased efficiency and minimal ingestion into the stomach. [Extracted from the article]

Researchers at University Rovira i Virgili in Tarragona, Spain, conducted a study on bitter taste receptors (TAS2R) along the gastrointestinal tract and their impact on enterohormone secretion. The study found that TAS2R14 had the highest expression levels in all tissues analyzed, while TAS2R39, -38, and -42 had consistently lower levels. Ageing was shown to upregulate certain TAS2R receptors in the colon, affecting hormone secretion. The research suggests potential targeted strategies for improving health outcomes through dietary interventions based on bitter taste receptors. [Extracted from the article]

The article discusses a study on the potential use of bitter taste receptor agonists to induce apoptosis in papillary thyroid cancer cells. The research found that activation of these receptors led to decreased cell viability and increased apoptosis in the cancer cells. Higher expression of a specific bitter taste receptor gene, TAS2R14, was associated with better progression-free survival in patients, suggesting a potential therapeutic relevance in managing thyroid cancer. The study highlights the importance of exploring alternative treatment options for thyroid cancer based on the activation of taste receptors. [Extracted from the article]

A recent study conducted by researchers at the Lithuanian University of Health Sciences explored the role of the TAS2R16 protein and its single nucleotide variants in the development of pituitary adenoma (PA), a common benign tumor that affects the pituitary gland. The study included 221 healthy controls and 131 patients with PA from the Lithuanian population. The researchers found that the TAS2R16 rs978739 C allele was less common in the non-invasive PA group compared to the control group, and the TAS2R16 rs860170 CT genotype was associated with a reduced likelihood of developing non-invasive PA. Additionally, the PA group had higher serum levels of TAS2R16, and specific TAS2R16 variants were linked to increased serum protein concentrations in PA patients. Further research is needed to better understand the relationship between TAS2R16 and pituitary adenoma development. [Extracted from the article]

According to a preprint abstract, animals use their taste system to detect bacterial peptidoglycans in their environment and respond by modulating their cellular immune system. Specific PeptidoGlycan Receptor Proteins (PGRPs) in bitter taste neurons mediate signaling and control immune cell production in larvae. This taste-mediated sensing of bacteria primes the immune system and improves survival after infection in adult flies. The findings suggest that sensory inputs, such as taste, play an important role in protecting animals from bacterial infection by providing an adaptive response to potential pathogens. [Extracted from the article]

A study conducted by the Leibniz Institute for Food Systems Biology at the Technical University of Munich has found that bitter-tasting protein fragments, or peptides, are produced in the stomach during the digestion of the natural sweetener thaumatin. These peptides were shown to stimulate the acid secretion of human stomach cells and influence inflammatory reactions in a cellular test system. The study suggests that further research should be conducted to better understand the health effects and potential anti-inflammatory properties of thaumatin and its bitter cleavage products. Thaumatin is a natural sweetener commonly used in foods and drinks. [Extracted from the article]

The article presents new findings from Justus-Liebig-University regarding the effects of bitter tastants on gallbladder smooth muscle relaxation, showing that this occurs independently of tuft cells and bitter taste receptors. Topics discussed include the potential of bitter tastants as smooth muscle relaxants, the specific bitter compounds tested, and the molecular mechanisms behind their relaxing effects on gallbladder motility.

New findings from the University of Pennsylvania Perelman School of Medicine highlight advances in the treatment of head and neck squamous cell carcinomas (HNSCCs). The research focuses on targeting GLUT1, a glucose transporter expressed by cancer cells, with a small molecule inhibitor called BAY-876. The study demonstrates that BAY-876 can decrease glucose uptake, viability, and metabolism in HNSCC cells, induce apoptosis, and enhance the effects of bitter taste receptor agonists. This combination treatment strategy shows promise for improving outcomes for HNSCC patients and warrants further exploration in future studies. [Extracted from the article]

A recent study conducted by researchers at the University of Piemonte Orientale in Novara, Italy, has found that bitter taste receptors (TAS2Rs) play a role in protecting monocytes and macrophages from oxidative stress damage. TAS2Rs are not only responsible for taste perception in the oral cavity but are also present throughout the body, forming a widespread chemosensory system. The researchers demonstrated that a specific TAS2R46 agonist called absinthin can counteract the release of reactive oxygen species (ROS) and reactive nitrogen species (RNS), reducing DNA damage in monocytes and macrophages. These findings suggest that TAS2R46 could be a novel player in protecting these immune cells from oxidative stress while supporting their antimicrobial activity. [Extracted from the article]

A new study from Queen's University in Kingston, Canada explores the role of taste receptors in cancer and metastasis. The research focuses on the activation of taste receptors by artificial and natural sweeteners and their effects on glycosylated receptors and signaling pathways. The study found that sweeteners can induce the epithelial-mesenchymal transition of cancer cells, promoting migration and invasion. Additionally, the sweeteners activated downstream signaling pathways, including NFkB, contributing to tumorigenesis and metastasis. This research provides insights into the potential impact of sweeteners on cancer progression. [Extracted from the article]

A recent study conducted by researchers from the Department of Food Science and Human Nutrition has discovered bitter masking compounds in allspice that could enhance the intake of bioactive compounds in functional foods and beverages. Bitter substances in these products can offer potential health benefits but their unpleasant taste reduces consumption. The study identified five compounds in allspice that exhibited bitter masking activity against quinine, with one compound acting as an antagonist of the TAS2R14 bitter receptor. This research provides valuable insights into the potential use of allspice in improving the sensory experience of functional foods and beverages. [Extracted from the article]

A new report from Jiangnan University in Wuxi, China, presents fresh data on food research. The study focuses on understanding the edulcorant profile of synthetic glucosyl steviol glycosides (GSGs) and rare natural steviol glycosides (SGs). The researchers developed a computational model based on the interactions of SG molecules with human sweet and bitter taste receptors, which demonstrated a high correlation between cumulative interaction energies and perceived sweetness. The study concludes that this model has the potential to predict the sweetness of SGs, GSGs, and mogrosides, aiding in the application or targeted synthesis of GSGs with desired sensory profiles. [Extracted from the article]

A group of scientists at the Monell Chemical Senses Center have identified a temporary taste blocker that works universally in people. The blocker, called AF-353, inhibits the transmission of taste signals and reduces the bitterness caused by medications and other taste compounds. Rinsing the mouth with AF-353 significantly reduced the bitterness of two important medicines used to treat parasites and hepatitis B and HIV. This discovery could improve compliance with medication, especially in children in developing countries. [Extracted from the article]

A recent study conducted by researchers at the Monell Chemical Senses Center has found that the sweet taste receptor, TAS1R2-TAS1R3, plays a role in regulating glucose metabolism in humans. The receptor, which is expressed in taste bud cells and certain intestinal cells, may facilitate glucose absorption and assimilation. The study showed that stimulation and inhibition of the receptor had different effects on glucose tolerance and insulin release. The researchers suggest that manipulating the receptor could have therapeutic potential for improving metabolic control. [Extracted from the article]

A recent study conducted by researchers at the University of North Carolina School of Medicine has revealed the protein structure of the TAS2R14 bitter taste receptor, shedding light on how we perceive bitter taste. The researchers discovered that when bitter-tasting substances come into contact with TAS2R14 receptors, they bind to a specific spot on the receptor, causing it to change shape and activate a protein called G protein. This triggers a series of biochemical reactions that ultimately lead to the perception of bitterness in the brain. The study also found that cholesterol plays a role in the activation of TAS2R14, and further research is needed to understand its exact function. This new knowledge could potentially aid in the development of drugs that regulate taste receptors and treat metabolic diseases such as obesity and diabetes. [Extracted from the article]

The article discusses a computational tool called VirtuousPocketome, which is designed to screen protein-ligand complexes and identify similar binding sites. By analyzing the structure of proteins, this tool can provide insights into their function and activation mechanisms, predict protein-ligand interactions, and aid in the development of therapeutic agents. The tool was tested on a human bitter taste receptor and identified 145 proteins with similar binding sites. This research has the potential to contribute to the understanding of tastants and their role in the diet and the design of compounds to target specific diseases. The tool is publicly accessible and can be applied to any protein-ligand complex. [Extracted from the article]

Researchers at the University of Turku in Finland have conducted a study on the potential use of cyclodextrins in food processing. Cyclodextrins are cyclic oligosaccharides that can encapsulate various compounds, such as phytochemicals and drugs. The researchers found that cyclodextrins have several applications in food processing, including improving color properties, inhibiting enzymatic browning, decreasing undesirable taste properties, and increasing the bioavailability and antioxidative activity of target compounds. However, successful use of cyclodextrins requires careful planning and understanding of the chemical composition of the food product. [Extracted from the article]

A study conducted at the University of Liverpool examined the sweet taste receptor T1R2-T1R3 in horses and its significance for energy provision and hydration. The research found that horses express T1R2, T1R3, and downstream signaling elements in their intestinal tissue, allowing for the potential stimulation of T1R2-T1R3 by sweeteners to increase glucose absorption and hydration. The study determined that sweeteners such as sucralose, stevia, and neohesperidin dihydrochalcone activate the horse T1R2-T1R3 receptor, while cyclamate does not. Understanding the sweetener specificity of the equine sweet receptor is important for developing dietary additives to optimize glucose absorption and hydration and prevent intestinal disease. [Extracted from the article]

A recent study conducted at the University of Pennsylvania has found that lidocaine, a local anesthetic, can induce apoptosis (cell death) in head and neck squamous cell carcinoma (HNSCC) through the activation of a bitter taste receptor called T2R14. The researchers discovered that lidocaine causes intracellular calcium mobilization and depolarizes mitochondria, leading to inhibited proliferation and apoptosis in HNSCC cells. The study also found that HPV-associated HNSCCs are associated with increased expression of the T2R14 receptor. These findings suggest that lidocaine may have therapeutic potential for HNSCC treatment, particularly in HPV-associated cases. Further clinical studies are warranted to explore this potential treatment option. [Extracted from the article]

A recent study published in the Journal of Cellular Physiology explores the functions of bitter taste receptors (TAS2Rs) in the reproductive system. The research suggests that TAS2Rs play potential roles in processes such as sperm chemotaxis, male fertility, ovarian function, uterine relaxation, prevention of preterm birth, infection defense, and cancer cell proliferation and apoptosis in reproductive cancers. The study highlights the need for further genetic and functional studies to deepen our understanding of TAS2Rs in reproduction and potentially develop novel therapeutic strategies for reproductive disorders. The research was conducted by the Department of Microbiology and Physiological Systems at UMass Chan Med Sch in Worcester, Massachusetts, with financial support from the NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development. [Extracted from the article]

A study conducted by researchers at Huaqiao University has found that sweet taste receptors in mice play a role in the increased urine output caused by artificial sweeteners. The study investigated the relationship between urinary excretion and the expression of sweet taste receptors in mice exposed to three different artificial sweeteners. The results showed that high doses of acesulfame potassium and saccharin significantly increased urine output, and there was a positive correlation between potassium levels and urination volume. The study suggests that sweet taste receptors, particularly in the bladder, are involved in the enhanced urine output caused by artificial sweeteners. [Extracted from the article]

A recent report from the University of Queensland in Brisbane, Australia discusses the role of bitter taste receptors (T2Rs) in cardiovascular physiology. The study found that T2Rs, which are typically associated with taste perception, are also expressed in the heart and may contribute to cardiovascular function. The researchers identified naturally occurring variants of T2Rs in human cardiac tissues and characterized their functional differences. These findings provide valuable insights into the role of T2Rs in the cardiovascular system and may have implications for understanding cardiovascular disease. [Extracted from the article]

Inventors Christof Goebel and Jan Schattner have filed a patent application for a device and system designed to assist patients with impaired or weak coughing in removing secretion from their airways. The device includes a respiratory gas source, a control unit, and a signal unit that emits signals to the patient to indicate changes in respiratory gas parameters. These signals are designed to be sensorially perceptible by the patient, potentially through mechanoreceptors or cold receptors, and are not visually perceptible. The device aims to improve synchronization between the patient and the respiratory therapy device without relying on disruptive or difficult to perceive acoustic or visual signals. The device can also include a detector signal and sensor to detect changes in airway patency and lung filling, allowing for automatic switching to a coughing phase. [Extracted from the article]

A study conducted by researchers at Chengdu University of Traditional Chinese Medicine in China explores the potential of using bitter compounds from traditional Chinese medicine to treat respiratory diseases. The study suggests that bitter compounds can reduce oxidative stress and other responses in respiratory diseases by targeting bitter taste receptors (T2Rs) in airway epithelium cells. The researchers propose that T2Rs could be a feasible drug target and alternative treatment option for respiratory diseases in the future. This research provides valuable insights for future studies on bitter receptor therapy related to respiratory diseases. [Extracted from the article]

A recent preprint abstract discusses the development of a computational tool called VirtuousPocketome, which is designed to screen protein-ligand complexes and identify similar binding sites. The tool aims to provide insights into protein function and activation mechanisms, predict protein-ligand interactions, and aid in the development of therapeutic agents. The researchers demonstrated the tool's potential by analyzing a human bitter taste receptor and identifying 145 proteins with similar binding sites. This work could have implications for understanding the role of tastants outside of the gustatory system and designing compounds to target proteins involved in specific diseases or disorders. The tool is publicly accessible and can be applied to any protein-ligand complex. [Extracted from the article]

A recent study conducted at Hokkaido University in Japan has found an association between bitter taste receptors (T2Rs) and obesity and diabetes. The study suggests that T2Rs in extraoral tissues, such as the intestine, adipose, muscle, liver, and pancreas, play a role in the development of these metabolic diseases. The researchers provide an overview of the current knowledge on T2Rs and their associations with obesity and diabetes. This information may be useful for individuals conducting research on bariatrics, diet and nutrition, and health and medicine. [Extracted from the article]

A recent study conducted by researchers at the University of Pennsylvania School of Medicine has found that lidocaine, a commonly used numbing agent, can activate certain bitter taste receptors in cancer cells, leading to their death. The study focused on head and neck cancers and found that lidocaine activates the bitter taste receptor T2R14, which triggers a process called apoptosis, causing the cancer cells to die. The researchers plan to conduct a clinical trial to test the addition of lidocaine to standard therapy for head and neck cancer patients. While lidocaine cannot cure cancer, this research offers potential for improving treatment options for this challenging form of cancer. [Extracted from the article]

A study conducted by researchers at Carol Davila University of Medicine and Pharmacy in Bucharest, Romania, explores the relationship between taste and the anti-cancer properties of phytochemicals. The study found that bitter taste was positively correlated with anti-cancer activity, while sweet taste was negatively correlated. The researchers suggest that bitter taste receptor agonists and sweet taste receptor antagonists may have a beneficial effect in slowing down the progression of inflammation to cancer. The study highlights the potential of using tastants as a therapeutic strategy for targeting inflammation and its links to cancer. [Extracted from the article]

A recent report from Jilin University in Changchun, China, explores the supramolecular clusters formed between ethanol and water in alcoholic beverages and their impact on taste and quality. The study utilized vibrational spectroscopic techniques to analyze the structures and hydrogen bond strength of these clusters. The research provides valuable insights into the composition of alcoholic beverages and may be of interest to researchers in the field of liquid science. The study was funded by the National Natural Science Foundation of China and the Jilin Provincial Science and Technology Development Plan Project. [Extracted from the article]

Keywords: Bone Marrow; Bone Marrow Cells; Bone Research; Health and Medicine; Hematology; Hematopoietic; Hematopoietic Stem Cells; Stem Cell Research EN Bone Marrow Bone Marrow Cells Bone Research Health and Medicine Hematology Hematopoietic Hematopoietic Stem Cells Stem Cell Research 1119 1119 1 11/06/23 20231109 NES 231109 2023 NOV 6 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Investigators publish new report on hematopoietic stem cells. Bone Marrow, Bone Marrow Cells, Bone Research, Health and Medicine, Hematology, Hematopoietic, Hematopoietic Stem Cells, Stem Cell Research. [Extracted from the article]

Keywords: Madrid; Spain; Europe; Adrenergic Bronchodilators; Bronchodilators; Cardiotonic; Cardiovascular Agents; Catecholamines; Drugs and Therapies; Health and Medicine; Isoproterenol Therapy; Nitric Oxide; Nitrogen Oxides; Pharmaceuticals; Respiratory Agents; Smooth Muscle; Sympathomimetic; Vasopressors EN Madrid Spain Europe Adrenergic Bronchodilators Bronchodilators Cardiotonic Cardiovascular Agents Catecholamines Drugs and Therapies Health and Medicine Isoproterenol Therapy Nitric Oxide Nitrogen Oxides Pharmaceuticals Respiratory Agents Smooth Muscle Sympathomimetic Vasopressors 2960 2960 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Drugs and Therapies - Isoproterenol Therapy. Madrid, Spain, Europe, Adrenergic Bronchodilators, Bronchodilators, Cardiotonic, Cardiovascular Agents, Catecholamines, Drugs and Therapies, Health and Medicine, Isoproterenol Therapy, Nitric Oxide, Nitrogen Oxides, Pharmaceuticals, Respiratory Agents, Smooth Muscle, Vasopressors, Sympathomimetic. [Extracted from the article]

Bariatrics, Diet and Nutrition, Health and Medicine, Nutrition Disorders, Nutritional and Metabolic Diseases and Conditions, Obesity, Overnutrition Keywords: Bariatrics; Diet and Nutrition; Health and Medicine; Nutrition Disorders; Nutritional and Metabolic Diseases and Conditions; Obesity; Overnutrition EN Bariatrics Diet and Nutrition Health and Medicine Nutrition Disorders Nutritional and Metabolic Diseases and Conditions Obesity Overnutrition 1360 1360 1 10/16/23 20231016 NES 231016 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in obesity. [Extracted from the article]

Keywords for this news article include: Chinese Academy of Agricultural Sciences, Sichuan, People's Republic of China, Asia, Food Science, Food Research, Organic Chemicals, Volatile Organic Compounds. Keywords: Food Research; Food Science; Organic Chemicals; Volatile Organic Compounds EN Food Research Food Science Organic Chemicals Volatile Organic Compounds 137 137 1 10/03/23 20231005 NES 231005 2023 OCT 5 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- Investigators publish new report on food science. [Extracted from the article]

We show, for the first time, experimentally the presence and functionality of a type 2 bitter receptor in human skeletal muscle cells." Three different cellular models were used: micro-dissected human skeletal tissues, human myoblasts/myotubes and human skeletal muscle cells differentiated from urine stem cells of healthy donors. Keywords: Drugs and Therapies; Muscle Cells; Pharmacology EN Drugs and Therapies Muscle Cells Pharmacology 1896 1896 1 09/25/23 20230929 NES 230929 2023 SEP 29 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on pharmacology. [Extracted from the article]

Keywords: Chemistry; Food Chemistry; Food Research EN Chemistry Food Chemistry Food Research 45 45 1 09/25/23 20230928 NES 230928 2023 SEP 28 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- Researchers detail new data in food research. Keywords for this news article include: Zhengzhou University, Zhengzhou, People's Republic of China, Asia, Food Research, Food Chemistry. [Extracted from the article]

Keywords: Antiinfectives; Antiretrovirals; Antivirals; Drugs and Therapies; HIV Protease Inhibitors; HIV/AIDS; Health and Medicine; Immune System Diseases and Conditions; Lopinavir Therapy; Pediatrics; Pharmaceuticals; Primate Lentiviruses; Protease Inhibitors; RNA Viruses; Retroviridae; Ritonavir Therapy; Thiazoles; Vertebrate Viruses; Viral Sexually Transmitted Diseases and Conditions EN Antiinfectives Antiretrovirals Antivirals Drugs and Therapies HIV Protease Inhibitors HIV/AIDS Health and Medicine Immune System Diseases and Conditions Lopinavir Therapy Pediatrics Pharmaceuticals Primate Lentiviruses Protease Inhibitors RNA Viruses Retroviridae Ritonavir Therapy Thiazoles Vertebrate Viruses Viral Sexually Transmitted Diseases and Conditions 107 107 1 09/11/23 20230911 NES 230911 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- New study results on HIV/AIDS have been published. According to news reporting originating from Northeastern University by NewsRx correspondents, research stated, "Lopinavir and ritonavir (LPV/r) are the primary anti-HIV drugs recommended by the World Health Organization for treating children aged three and above who are infected with the human immunodeficiency virus (HIV).". [Extracted from the article]

Bile acids activate extraoral bitter taste receptors "Our results suggest that there is indeed a physiological relationship between bile acids and certain extraoral bitter taste receptors and that the latter act as endogenous sensors of bile acid levels. Bitter taste receptors that respond to bile acids: The human bitter taste receptors TAS2R1, TAS2R4, TAS2R14, TAS2R39, and TAS2R46 responded to at least three of the bile acids tested. Bile acids tested included the primary bile acids cholic acid and chenodeoxycholic acid, the secondary bile acids lithocholic and deoxycholic acid, the tertiary bile acid ursodeoxycholic acid, as well as the conjugated bile acids taurolithocholic, glycocholic, and taurocholic acid. [Extracted from the article]

Keywords: Shanghai; People's Republic of China; Asia; Biosensors; Biotechnology; Chemicals; Electrochemicals; Food Industries; Nanotechnology EN Shanghai People's Republic of China Asia Biosensors Biotechnology Chemicals Electrochemicals Food Industries Nanotechnology 180 180 1 07/10/23 20230713 NES 230713 2023 JUL 13 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Biosensors is the subject of a report. For more information on this research see: Umami taste evaluation based on a novel mouse taste receptor cell-based biosensor. [Extracted from the article]

Keywords: As; Norway; Europe; Food Science; Business EN As Norway Europe Food Science Business 141 141 1 06/19/23 20230622 NES 230622 2023 JUN 22 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- A new study on Food Science is now available. Keywords for this news article include: As, Norway, Europe, Food Science, Business, Nofima AS. [Extracted from the article]