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A descriptive study was conducted to assess the knowledge on first aid measures among self help group members. The study was conducted in selected community areas of Natekal PHC. The sample for the study comprised of 100 self help group members selected by purposive sampling technique. The data was collected between 2nd October 2011 and 13th November 2011 by using structured questionnaires. The data was analyzed using descriptive and inferential statistics. The study finding revealed that majority of the samples 55% were in the age group of 25-30 years, 64% were females, 44% of them were manual laborers and 39 % received information from the teaching programs, 20% from mass media 13% from friends and 17% of them do not have exposure to any source of information about the first aid practices. The results showed that majority of the samples 62% had good knowledge, and 38% had average knowledge about the first aid practice. Among the seven areas of the knowledge assessment on first aid measures the mean percentage score of the samples were highest (70%) in the area of poisoning and lowest score (28.8%) in the area of bleeding. There is no significant association between knowledge and selected demographic variables like age, educational status, membership in any social organization, occupation, place of living, and source of information other than gender. [ABSTRACT FROM AUTHOR]