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12 results on '"Lionel Hervé"'

1. Multispectral Total-variation Reconstruction Applied to Lens-free Microscopy

Author

Cédric Allier, Fabrice Navarro, Pierre Blandin, Olivier Cioni, Lionel Hervé, Mathilde Menneteau, Thomas Bordy, Sophie Morales, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

Subjects
0301 basic medicine, Materials science, Multispectral image, Video microscopy, 01 natural sciences, Article, law.invention, 010309 optics, [SPI]Engineering Sciences [physics], 03 medical and health sciences, Optics, law, 0103 physical sciences, Microscopy, Variation (astronomy), Image resolution, 030304 developmental biology, 0303 health sciences, business.industry, Inverse problem, Atomic and Molecular Physics, and Optics, Ptychography, Lens (optics), Light intensity, 030104 developmental biology, Computer Science::Computer Vision and Pattern Recognition, business, Partial coherence, Biotechnology
Abstract

International audience; Lens-free microscopy multispectral acquisitions are processed with an inverse problem approach: a multispectral total variation criterion is defined and minimized with the conjugate gradients method. Reconstruction results show that the method is efficient to recover the phase image of densely packed cells.

Published
2018
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2. Time Resolved optical detection for white matter lesion detection: preclinical tests on macaque brains and MRI co-registration

Author

Lev Stimmer, Julien Flament, Lionel Hervé, L. Watroba, M. Berger, J.-M. Dinten, P. Aubourg, Anne Planat-Chrétien, Joanna Demilly, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service MIRCEN (MIRCEN), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Institut de Biologie François JACOB (JACOB), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
Pathology, medicine.medical_specialty, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, education, White matter lesion, Co registration, Macaque, 01 natural sciences, 010309 optics, 03 medical and health sciences, 0302 clinical medicine, Optical imaging, Neuroimaging, biology.animal, 0103 physical sciences, Medicine, 030304 developmental biology, 0303 health sciences, biology, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, Hyperintensity, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Tomography, business, Nuclear medicine, 030217 neurology & neurosurgery
Abstract

International audience; We conducted a preclinical assessment on young macaques aimed at detecting white matter lesions. We present the protocol we implemented to achieve the lesions detection using a bedside non-invasive optical-based Time-Resolved instrumentation we have optimized for this purpose. We validated the reconstructed 3D absorption map with co-registration of MRI data. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

Published
2015
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3. Time-resolved diffuse optical tomography for non-invasive flap viability assessment: pre-clinical tests on rats

Author

Jean-Luc Coll, Henri Grateau, M. Aribert, Lionel Hervé, A. Dalla Mora, L. Di Sieno, Georges Bettega, A. Puszka, M. Berger, Anne Planat-Chrétien, Antonio Pifferi, Cynthia Hamou, Davide Contini, and J.-M. Dinten

Subjects
Clinical tests, Materials science, Image reconstruction techniques, Biomaterials, Optics, Atomic and Molecular Physics, Nuclear Medicine and Imaging, Medical optics instrumentation, otorhinolaryngologic diseases, Electronic, Optical and Magnetic Materials, Tomography, business.industry, Non invasive, equipment and supplies, Diffuse optical imaging, Light propagation in tissues, Optical diagnostics for medicine, Time-resolved imaging, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Radiology, Nuclear Medicine and Imaging, and Optics, business, Industrial process imaging, Radiology, Biomedical engineering
Abstract

We present a new setup for time-resolved diffuse optical tomography based on multiple source-detector acquisitions analysed by means of the Mellin-Laplace transform. The proposed setup has been used to perform pre-clinical measurements on rats in order to show its suitability for non-invasive assessment of flap viability.

Published
2015
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5. Time-Resolved Reflectance DOT: Experimental Results for Imaging Absorption Contrast in Depth

Author

Jacques Derouard, Agathe Puszka, Jean-Marc Dinten, Anne Planat-Chrétien, Mathieu Debourdeau, Lionel Hervé, Anne Koenig, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy ), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy), and Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Point spread function, Photon, Materials science, Tomographic reconstruction, business.industry, Instrumentation, media_common.quotation_subject, 010401 analytical chemistry, 01 natural sciences, Reflectivity, Diffuse optical imaging, 030218 nuclear medicine & medical imaging, 0104 chemical sciences, Absorption contrast, 03 medical and health sciences, 0302 clinical medicine, Optics, Contrast (vision), business, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, media_common
Abstract

International audience; Detecting and localizing precisely contrast in depth is the major challenge of reflectance Diffuse Optical Tomography. We present a dedicated time-resolved instrumentation and first experimental results using a Mellin-Laplace Transform based method.

Published
2012
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6. Time-Resolved Reflectance Diffuse Optical Tomography by using Mellin-Laplace Transform

Author

Agathe Puszka, Anne Planat-Chrétien, Anne Koenig, Jean-Marc Dinten, Lionel Hervé, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

Subjects
Optics, Materials science, Light propagation, Laplace transform, business.industry, Attenuation coefficient, Physics::Optics, business, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, Reflectivity, Diffuse optical imaging
Abstract

International audience; In this paper, we show how the Mellin-Laplace Transform helps to obtain robust and relevant reconstructions of deep optical heterogeneity from time-resolved diffuse optical tomography measurements.

Published
2012
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8. Non-Negative Matrix Factorization to unmix several fluorescence spectra and remove autofluorescence from in vivo spectrally resolved acquisitions

Author

Jean-Marc Dinten, Anne-Sophie Montcuquet, Fabrice Navarro, Lionel Hervé, and Jerome Mars

Subjects
Specific fluorescence, Autofluorescence, Nuclear magnetic resonance, In vivo, Chemistry, Blind signal separation, Fluorescence spectra, Near infrared radiation, Fluorescence, Non-negative matrix factorization
Abstract

Plurality of specific fluorescent markers in multiplexing, and autofluorescence of biological tissues limit specific fluorescence detection. A spectroscopic approach and a blind source separation method are proposed to unmix multiple fluorescence spectra and remove autofluorescence.

Published
2010
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9. Quantitative results of a bi-modal X-ray fDOT system in a cylindrical geometry

Author

Anne Planat-Chrétien, Lionel Hervé, Ludovic Lecordier, Jean-Guillaume Coutard, Jean-Marc Dinten, Anne Koenig, and Marco Brambilla

Subjects
Coupling, Cylindrical geometry, Materials science, Bi modal, Optics, Molecular fluorescence, business.industry, X-ray, Image processing, Focus (optics), business, Diffuse optical imaging
Abstract

We develop a new instrument that couple cylindrical fluorescence diffuse optical tomography to a micro XCT system. We focus on the effective coupling between both modalities via the fDOT algorithm. Quantitative results are provided.

Published
2010
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10. Non-Negative Matrix Factorization to remove autofluorescence of tissues and improve FDOT

Author

Anne-Sophie Montcuquet, Jean-Marc Dinten, Lionel Hervé, and Jerome Mars

Subjects
Autofluorescence, Optics, Materials science, Infrared, business.industry, Tomography, business, Blind signal separation, Signal, Fluorescence, Diffuse optical imaging, Non-negative matrix factorization
Abstract

Autofluorescence of biological tissues limits deep fluorescent markers detection. A spectroscopic approach and a blind source separation method are explored to remove the autofluorescence signal. We show how this pre-processing improves Fluorescent Diffuse Optical Tomography.

Published
2010
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11. A Finite Volume Method for Fluorescence Diffuse Optical Tomography: Influence on Forward Model and Reconstruction

Author

Lionel Hervé, Françoise Peyrin, Jean-Marc Dinten, and Ludovic Lecordier

Subjects
Physics, Optics, Finite volume method, business.industry, Attenuation coefficient, Tomography, business, Fluorescence, Photon counting, Diffuse optical imaging, Finite element method
Abstract

This paper presents a finite volume method to compute the forward model in fluorescence diffuse optical tomography. The method is compared to the finite element method in regards of both forward model and reconstruction accuracy.

Published
2010
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12. Whole Body Animal Examination by Fluorescence Tomography

Author

Michel Berger, Lionel Hervé, Philippe Peltie, Jérôme Boutet, Véronique Josserand, Philippe Rizo, Isabelle Texier, Anne Koenig, Jean-Luc Coll, Jean-Marc Dinten, and Anabela Da Silva

Subjects
Pathology, medicine.medical_specialty, Materials science, business.industry, medicine, White light, Lung tumours, Whole body, Nuclear medicine, business, Fluorescence, Diffuse optical imaging, Fluorescence tomography
Abstract

A fluorescent diffuse optical tomography instrument has been developed in our laboratory. Taking into account in-homogeneities, it allows whole body examination. Experimental results obtained with this system on mice deep lung tumours examination are presented.

Published
2006
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