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Your search keyword '"Diculescu, Mircea"' showing total 2 results
Start Over Author "Diculescu, Mircea" Topic inflammatory bowel diseases Publisher oxford university press
2 results on '"Diculescu, Mircea"'

1. Diagnostic Delay in Romanian Patients with Inflammatory Bowel Disease: Risk Factors and Impact on the Disease Course and Need for Surgery.

Author

Zaharie R, Tantau A, Zaharie F, Tantau M, Gheorghe L, Gheorghe C, Gologan S, Cijevschi C, Trifan A, Dobru D, Goldis A, Constantinescu G, Iacob R, and Diculescu M

Subjects
Adult, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Inflammatory Bowel Diseases complications, Inflammatory Bowel Diseases surgery, Logistic Models, Male, Middle Aged, Outcome Assessment, Health Care, Registries, Risk Factors, Romania, Time Factors, Delayed Diagnosis statistics & numerical data, Inflammatory Bowel Diseases diagnosis
Abstract

Background: The epidemiology of inflammatory bowel disease [IBD] in Eastern Europe is poorly understood, particularly with regard to diagnostic delay. Here we investigated the factors leading to delayed diagnosis and the effect of the delay on several disease progression and outcome measures., Methods: A total of 1196 IBD cases [682 ulcerative colitis [UC], 478 Crohn's disease [CD], 36 indeterminate colitis] from the Romanian national registry IBDPROSPECT were reviewed. Standard clinical and demographic factors were evaluated as predictors of a long diagnostic delay in both CD and UC. Diagnostic delay was subsequently evaluated as a potential risk factor for bowel stenoses, bowel fistulas, perianal fistulas, perianal surgery, and intestinal surgery in CD patients., Results: The median diagnostic delay was significantly longer in CD [5 months] than in UC [1 month] patients [p < 0.001]. Compared with 5 months for UC patients, 75% of CD patients were diagnosed within 18 months of symptom onset. In CD patients, extra-ileal location was a protective factor (odds ratio [OR], 0.5; p = 0.03), whereas being an active smoker [OR, 2.09; p = 0.01] and symptom onset during summer [OR, 3.35; p < 0.001] were independent risk factors for a long diagnostic delay [> 18 months]. In UC patients, an age > 40 years was a protective factor [OR, 0.68; p = 0.04] for a long delay. Regarding outcomes, a long diagnostic delay in CD patients positively correlated with bowel stenoses [OR, 3.38; p < 0.01] and any IBD-related surgery [OR, 1.95; p = 0.03] and had a positive trend for intestinal fistulas [OR, 2.64; p = 0.08] and perianal fistulas [OR, 2.9; p = 0.07]. Disease duration since diagnosis positively correlated with bowel stenoses [OR, 1.04; p = 0.04], any IBD-related surgery [OR, 1.04; p = 0.02], and intestinal surgery [OR, 1.07; p < 0.01]., Conclusions: A long diagnostic delay in IBD correlates with an increased frequency of bowel stenoses and need for IBD-related surgery., (Copyright © 2015 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.)

Published
2016
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2. Worldwide Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: An International Survey

Author

Bernstein, Charles N, Ng, Siew C, Banerjee, Rupa, Steinwurz, Flavio, Shen, Bo, Carbonnel, Franck, Hamid, Saeed, Sood, Ajit, Yamamoto-Furusho, Jesus K, Griffiths, Anne, Benchimol, Eric I, Travis, Simon, Lopes, Susana, Rubin, David T, Kaplan, Gilaad G, Armstrong, David, Gearry, Richard, Rahman, M Masudur, Mohsin, Mostafa N, Vieira, Andrea, Salgado, Nayara Carvalho, Machado, Marta Brenner, Wu, Hao, Mak, Joyce W Y, Miao, Ying-Lei, Abdullah, Murdani, Chowers, Yehuda, Ogutu, Elly, Devani, Smita, Yang, Suk-Kyun, Omar, Mahmoud, Goh, K L, Hilmi, Ida, Raja Ali, Raja Affendi, Aye, Than Than, Wai, Tin Moe, Joshi, Neeraj, Abbas, Zaigham, Magro, Fernando, Sollano, Jose, Torres, Esther A, Mohiuddin, Syed Adnan, Diculescu, Mircea, Almadi, Majid, Ong, David, Watermeyer, Gillian, Metthananda, Navarathne, Wei, Shuchen, Limsrivilai, Julajak, Pausawasdi, Nonthalee, Pisepongsa, Pises, Kochhar, Gursimran, Rodríguez, Ximena, and Viet, Dao

Subjects
medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Ibdjnl/9, COVID-9, Global Health, Inflammatory bowel disease, 03 medical and health sciences, Original Research Article—Clinical, 0302 clinical medicine, inflammatory bowel disease, Pandemic, Health care, medicine, Immunology and Allergy, Humans, Practice Patterns, Physicians', 030304 developmental biology, AcademicSubjects/MED00260, 0303 health sciences, business.industry, SARS-CoV-2, pandemic, International survey, Gastroenterology, COVID-19, Disease Management, Guideline, medicine.disease, Inflammatory Bowel Diseases, 3. Good health, Underlying disease, Steroid use, Family medicine, Health Care Surveys, 030211 gastroenterology & hepatology, immunomodulatory therapy, business, management
Abstract

Background and Aims Persons with inflammatory bowel disease (IBD) may be particularly vulnerable to COVID-19 either because of their underlying disease or its management. Guidance has been presented on the management of persons with IBD in the time of this pandemic by different groups. We aimed to determine how gastroenterologists around the world were approaching the management of IBD. Methods Members of the World Gastroenterology Organization (WGO) IBD Task Force contacted colleagues in countries largely beyond North America and Europe, inviting them to review the WGO website for IBD and COVID-19 introduction, with links to guideline documents, and then to respond to 9 ancillary open-ended management questions. Results Fifty-two gastroenterologists from 33 countries across 6 continents completed the survey (April 14 to May 16, 2020). They were all adhering for the most part to published guidelines on IBD management in the COVID-19 era. Some differences and reductions in services related to access, and some related to approach within their communities in terms of limiting virus spread. In particular, most gastroenterologists reduced in-person clinics (43 of 52), limited steroid use (47 of 51), limited elective endoscopy (45 of 52), and limited elective surgeries (48 of 51). If a patient was diagnosed with COVID-19, immunomodulatory therapy was mostly held. Conclusions In most countries, the COVID-19 pandemic significantly altered the approach to persons with IBD. The few exceptions were mostly based on low burden of COVID-19 in individual communities. Regardless of resources or health care systems, gastroenterologists around the world took a similar approach to the management of IBD.

Published
2020

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