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Background/objectives: The aim of this study was to evaluate large field of view (FoV) subjective image quality of three cone-beam computed tomography (CBCT) machines to assess the threshold for reliable diagnostic perceptibility when lowering exposure settings., Materials and Methods: One entire cadaver's head was scanned using three CBCT scanners. The largest available FoV of each device, imaging orthodontic relevant structures, was applied. CBCT datasets with different image quality based on standard to minimum scanning parameters were acquired. Five dentists evaluated the visibility of selected anatomical structures of the upper and lower jaw using a 5-point rating scale., Results: Image quality depends on parameters such as a minimum voxel size of 0.2 to 0.4mm or a minimum of 4mA. A reduction in number of images (scanning protocol) reduces image quality. Visualization of different anatomical structures for orthodontic treatment planning requires distinct scanning protocols to support adequate perception of these structures., Limitations: This study does not account for the evaluation of paediatric anatomical structures due to the availability of cadaver's head., Conclusions: CBCT scans performed for orthodontic purposes using a large FoV with reduced parameters (400 µm, 2 to 4 mA and low dose protocols) are acceptable for visualization of large anatomical structures. Further lowering these parameters will not be sufficient to view small anatomical structures. Orthodontic indications will have to define specific anatomical structures to choose adequate scanning protocols to reduce dose and ensure reliable diagnostic visibility., (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)

Objectives: To compare condylar development and changes in condylar radiological appearance in patients with idiopathic condylar resorption (ICR) to a healthy, age- and gender matched, control group., Materials and Methods: This case-control study included 16 ICR patients [mean age: 15years, 9 months; standard deviation (SD): 4 years) and 16 controls (mean age: 16 years, 8 months; SD: 4 years, 7 months), with diagnostic (T0) and 2-year follow-up (T1) CBCT examinations. Condylar changes were evaluated through changes in condylar neck angle (CNA), and the transversal, vertical and anteroposterior displacement of five condylar points between T0 and T1. The magnitude and direction of condylar changes were evaluated using vector analyses. A qualitative radiological evaluation of the TMJ was performed based on healthy, erosive and repaired morphological appearance. Linear and angular measurements were assessed using ANOVA and a Tukey post-hoc test, and vectors were tested using an independent-sample 2-tailed t-test. Fisher's exact test was used for the qualitative evaluation., Results: At T0, ICR patients exhibited decreased condylar height, smaller condylar width and posteriorly inclined CNA compared with the control group (P < 0.05). During observation, condylar vertical growth was smaller in the ICR group than in the control group (P < 0.05). Vector analysis showed an upward direction of vertical displacement for all condylar points in the control group; the ICR group showed a downward direction (P < 0.003). The radiological appearance of 75% of the ICR condyles and 94% of the control condyles did not change during the 2-year follow-up period., Conclusions: ICR condyles displayed reduced vertical development compared with control condyles. The radiological appearance remained unchanged for most joints. Observed changes in radiological appearance did not always follow a progressive model of degenerative joint disease., (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)

Objective: To analyze whether the decreased bone density due to the manipulation of bone remodeling rate has an influence on the type of the planned tooth movement., Materials and Methods: A finite element model of a lower incisor has been developed. The density of the alveolar bone surrounding the tooth has been assumed to simulate the one occurring after corticotomy to increase tooth movement rate. Moment-to-force ratios corresponding to three different types of movements have been simulated; uncontrolled tipping, translation, and root movement. The three tooth movements have been analyzed in both corticotomized and non-corticotomized simulations, and the final effects on the amount and type of tooth movement analyzed. The stress and strain levels in the periodontal ligament have been analyzed too., Results: The amount of tooth movement obtained in case of lower bone density is higher in all types of movement simulations. The centre of rotation of the movement shifts more apically in case of translation, controlled and uncontrolled tipping. In the corticotomy simulations, the compressive stresses in the periodontal ligament decreased while the tensile stresses increased., Conclusion: A decreased bone density influences not only the amount of tooth movement, but also its type. This study suggests that the moment-to-force ratios used in conventional orthodontics should be modified in case of techniques that decrease bone density to enhance tooth movement rate., (© The Author 2017. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com)

Thermodynamic nickel-titanium (NiTi) wires have become increasingly popular. The relationship between the temperature variation within the mouth and the force level delivered is, however, far from elucidated. The aim of this study was to evaluate the influence of possible intraoral temperature differences on the forces exerted by seven commercially available 0.019 x 0.025 inch NiTi archwires. As mouth temperature ranges from 33 to 37 degrees C most of the time, all wires were tested at five different temperatures between 30 and 40 degrees C in an orthodontic wire-testing device, a so-called Force System Identification (FSI) apparatus, placed in a climate chamber. In the FSI a two-bracket system using self-ligating Damon brackets simulated first order displacements up to 4 mm. At each temperature five samples of each archwire brand were tested. The following variables from the activation/deactivation curves were calculated: force and displacement at the yield point, maximum force level, total energy up to maximum displacement, energy loss after deactivation, force and displacement at the beginning and at the finish of the plateau, and the slope of the plateau. Any statistically significant differences in these variables for the different brands and temperature levels were analysed using one-way analysis of variance. The results showed that: (1) The behaviour of all wires was different. (2) Copper NiTi40 showed the lowest and the most constant force level, followed by NeoSentalloy 200 g. On the other hand, these wires may not work properly in mouth breathers as no forces were exerted below 35 degrees C. (3) If the use of superelastic characteristics and low force levels are the reasons for utilizing rectangular NiTi wires, austenitic NiTi wires should be avoided.

The risk of developing bony dehiscence and gingival recession may lead clinicians to prefer extraction to expansion in borderline cases. The purpose of this research was to compare changes in clinical crown height that occur at the buccal aspect of the maxillary lateral teeth of adult patients in which the transverse dimension was increased with those occurring if no expansion had been performed. Secondly it was the intention to identify factors increasing the risk of development of gingival recessions. The material comprised the pre- and post-treatment study casts from two groups of 50 adult patients. In one group an average transverse expansion of 3 mm was performed while in the other no change in the arch width was generated during treatment. Clinical crown heights of the two groups before and after treatment were compared with a Student's t-test and correlation analysis was used to determine whether any demographic or treatment-related parameters could be applied to predict an increase in clinical crown height. The increase in transarch width was greater in males (2.4-3.4 mm) than in females (1.8-2.5 mm), and greater at the level of the premolars than at the molars. No significant increase in buccal crown height could be identified. The increase in width was, however, related to buccal tipping as a positive correlation was found between the amount of expansion and tipping (P < 0.01). No detrimental effect of slow maxillary expansion could be demonstrated.

Microcracks and microdamage have been associated with bone remodelling. The aim of this study was to investigate the role of microcracks as a trigger for alveolar bone remodelling after the application of an orthodontic load. In 25 3-month-old male Danish land-race pigs, the lower right first molar was moved buccally with a force of 130 cN. The contralateral molar was not treated and was used as an internal control. After 1, 2, 4, 7 and 15 days of treatment, the regions containing the right and left molars were excised and en bloc stained in basic fuchsin. The presence of microcracks on the buccal and lingual sides of both treated and untreated teeth was detected and expressed as crack density (number/mm2). The buccal treated side showed significantly more cracks than the buccal untreated side at day 1. This difference was significantly larger than that observed at days 2, 7 and 15. The same side showed significantly more microcracks than the lingual treated side at day 1, and this difference was larger compared with that observed at days 4 and 15. The presence of more microcracks on the treated side than on the untreated side suggests a role for microcracks in the initiation of bone remodelling after orthodontic loading. The increased presence of microcracks on the side towards which the tooth was moved, and where bone resorption is usually observed, suggests that microcracks could represent the first damage induced by orthodontic force that has to be repaired by bone remodelling. Finally, the strain levels in the alveolar bone during the orthodontic load transfer in the experiment were examined by finite element (FE) analysis. Although this showed that the strains were very low (10-100 microstrain), it should be noted that occlusal loading was not taken into account. In addition, high-resolution microtomography of the alveolar bone/periodontal ligament (PDL) interface revealed that the actual surface of the alveolar bone was very rough, predisposing it to high local stress/strain peaks.

The aim of this study was to determine, in a rat model, whether a state of high or low bone turnover had an effect on the rate and type of tooth movement and on the incidence of root resorption induced by orthodontic treatment. The maxillary left first molar was moved mesially for 21 days in 52 6-month-old Wistar rats. They were divided into three groups: group 1 (n = 19) with normal bone turnover, group 2 (n = 16) with high bone turnover, and group 3 (n = 17) with low bone turnover. The contralateral side was left untreated to act as a control. The different metabolic rates were created by inducing hyper- and hypothyroidism. The amount of tooth movement was measured using an electronic calliper and the location of the centre of rotation (CRot) was determined after microcomputer tomographic scanning and subsequent three-dimensional reconstruction. Histomorphometric evaluation of root resorption was performed on undecalcified 7 microm thick sections of the maxilla and the differences between treated and untreated sides were evaluated. The results showed that high bone turnover increased the amount of tooth movement compared with the normal or low bone turnover state. There was no statistical difference in the location of the CRot. The treated side presented more root resorption than the untreated side, but this difference was not influenced by the metabolic rates. On the contrary, the untreated side in the low bone turnover group showed more root resorption, suggesting that in subjects where a decreased bone turnover rate is expected, the risk of root resorption could be increased.

Objective: The present study addresses the question--can PTH induce formation of trabeculae in areas where cancellous bone has disappeared? Two-year-old male rats were chosen, because in this aged animal model the distal femurs have almost no cancellous bone, and the marrow cavity has reached a substantial dimension., Design: The rats were injected for 56 days with either PTH(1-34), 15 nmol/kg/day (62.5 microg/kg/day), or vehicle., Methods: Transverse specimens, 2-mm high, were cut from the distal femoral metaphysis. Marrow cavity diameters and cancellous bone trabeculae were analysed by a micro-computerized tomography scanner. The cancellous bone within the cortical and endocortical rim of each specimen was submitted to a biomechanical compression test. Furthermore, the cancellous bone was studied by dynamic tetracycline labelling and histomorphometry., Results: In the vehicle-injected group the trabecular bone volume was 0% (0-1.4), median (range). All PTH-injected rats had trabeculae in the distal metaphysis and the trabecular bone volume (6.7% (2.3-12.0)) was markedly increased (P<0.003). The median trabecular thickness was increased (P<0.003) in the PTH-injected rats (118 microm (104-125)) compared with the vehicle group (0 microm (0-71)). The compressive stress was increased (P<0.003) in the PTH-injected group (0.7 MPa (0.1-2.1)) compared with the vehicle-injected group (0 MPa (0-0.4)). The histomorphometry revealed that only 3 animals of the 10 in the vehicle-injected group had trabeculae in the distal femoral metaphysis. All PTH-injected animals (12 of 12) had continuous trabecular bone network in the marrow cavity., Conclusion: Intermittent PTH treatment induced marked formation of new cancellous bone trabeculae with substantial mechanical strength, at a site where it had disappeared in old rats.