1. Latent tuberculosis infection prevalence in rural Madagascar.
- Author
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Sadananda G, Knoblauch AM, Andriamiadanarivo A, Razafindrina K, Ambinintsoa I, Rabetombosoa RM, Pando CE, Tsang LY, Small PM, Rakotosamimanana N, and Grandjean Lapierre S
- Subjects
- Adult, Humans, Interferon-gamma Release Tests, Madagascar epidemiology, Prevalence, Tuberculin Test, Latent Tuberculosis diagnosis, Latent Tuberculosis epidemiology
- Abstract
Background: Understanding latent Mycobacterium tuberculosis infection (LTBI) prevalence is crucial for the design of TB control strategies. There are no data on LTBI in rural Madagascar., Methods: Tuberculin skin tests were performed in 98 adults aged >15 y in five rural villages in the Ifanadiana district, Madagascar., Results: Of adults, 78.6% were positive for LTBI, ranging between 28.6% and 95.0% among villages. The majority (65.3%) showed an induration reaction of >15 mm., Conclusions: LTBI prevalence is high in rural Madagascar. Long-term TB control strategies including LTBI testing and treatment must account for high and heterogeneous prevalence in remote, underdeveloped areas., (© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)
- Published
- 2020
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