1. Corrigendum to: Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice
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Tognin, Stefania, van Hell, Hendrika H, Merritt, Kate, Winter-van Rossum, Inge, Bossong, Matthijs G, Kempton, Matthew J, Modinos, Gemma, Fusar-Poli, Paolo, Mechelli, Andrea, Dazzan, Paola, Maat, Arija, de Haan, Lieuwe, Crespo-Facorro, Benedicto, Glenthøj, Birte, Lawrie, Stephen M, McDonald, Colm, Gruber, Oliver, van Amelsvoort, Therese, Arango, Celso, Kircher, Tilo, Nelson, Barnaby, Galderisi, Silvana, Bressan, Rodrigo, Kwon, Jun S, Weiser, Mark, Mizrahi, Romina, Sachs, Gabriele, Maatz, Anke, Kahn, René, McGuire, Phillip, McGuire, Philip, Kempton, Matthew, Gifford, George, Petros, Natalia, Antoniades, Mathilde, De Micheli, Andrea, Vieira, Sandra, Spencer, Tom J, Scarpazza, Cristina, Hird, Emily, Kahn, Rene, van Hell, Erika, Winter, Inge, Cahn, Wiepke, Schnack, Hugo, Siegmann, Dieuwke, Barkhof, Jana, Hendriks, Lotte, de Wit, Iris, Tordesillas-Gutierrez, Diana, Setien-Suero, Esther, Ayesa-Arriola, Rosa, Suarez-Pinilla, Paula, Ramirez-Bonilla, MariaLuz, Garcia-de la foz, Victor Ortiz, Erlang Sørensen, Mikkel, Tangmose, Karen, Schæbel, Helle, Broberg, Brian, Rostrup, Egill, Lawrie, Stephen, Hallahan, Brian, Cannon, Dara, McLoughlin, James, Finnegan, Martha, Deckers, Danny, Marcelis, Machteld, Vingerhoets, Claudia, Díaz-Caneja, Covadonga M, Ayora, Miriam, Janssen, Joost, Rodríguez-Jiménez, Roberto, Díaz-Marsá, Marina, Falkenberg, Irina, Bitsch, Florian, Berger, Philipp, Sommer, Jens, Raab, Kyeon, Jakobi, Babette, McGorry, Patrick, Amminger, Paul, McHugh, Meredith, Mucci, Armida, Bucci, Paola, Piegari, Giuseppe, Pietrafesa, Daria, Nicita, Alessia, Patriarca, Sara, Zugman, André, Gadelha, Ary, Rodrigues da Cunha, Graccielle, Soo Kwon, Jun, Kevin Cho, Kang I k, Young Lee, Tae, Kim, Minah, Bin Kwak, Yoo, Jeong Hwang, Wu, Kiang, Michael, Gerritsen, Cory, Maheandiran, Margaret, Ahmed, Sarah, Prce, Ivana, Lepock, Jenny, Willeit, Matthäus, Lenczowski, Marzena, Sauerzopf, Ullrich, Weidenauer, Ana, Furtner-Srajer, Julia, Kirschner, Matthias, Burrer, Achim, Stämpfli, Philipp, Huber, Naemi, Kaiser, Stefan, Kawohl, Wolfram, Brammer, Michael, Young, Jonathan, Bullmore, Edward, Morgan, Sarah, European Commission, University of Zurich, PSYSCAN Consortium, Tognin, Stefania, van Hell, Hendrika H, Merritt, Kate, Winter-van Rossum, Inge, Bossong, Matthijs G, Kempton, Matthew J, Modinos, Gemma, Fusar-Poli, Paolo, Mechelli, Andrea, Dazzan, Paola, Maat, Arija, de Haan, Lieuwe, Crespo-Facorro, Benedicto, Glenthøj, Birte, Lawrie, Stephen M, Mcdonald, Colm, Gruber, Oliver, van Amelsvoort, Therese, Arango, Celso, Kircher, Tilo, Nelson, Barnaby, Galderisi, Silvana, Bressan, Rodrigo, Kwon, Jun S, Weiser, Mark, Mizrahi, Romina, Sachs, Gabriele, Maatz, Anke, Kahn, René, Mcguire, Phillip, Mcguire, Philip, Kempton, Matthew, Gifford, George, Petros, Natalia, Antoniades, Mathilde, De Micheli, Andrea, Vieira, Sandra, Spencer, Tom J, Scarpazza, Cristina, Hird, Emily, Kahn, Rene, van Hell, Erika, Winter, Inge, Cahn, Wiepke, Schnack, Hugo, Siegmann, Dieuwke, Barkhof, Jana, Hendriks, Lotte, de Wit, Iri, Tordesillas-Gutierrez, Diana, Setien-Suero, Esther, Ayesa-Arriola, Rosa, Suarez-Pinilla, Paula, Ramirez-Bonilla, Marialuz, Garcia-de la foz, Victor Ortiz, Erlang Sørensen, Mikkel, Tangmose, Karen, Schæbel, Helle, Broberg, Brian, Rostrup, Egill, Lawrie, Stephen, Hallahan, Brian, Cannon, Dara, Mcloughlin, Jame, Finnegan, Martha, Deckers, Danny, Marcelis, Machteld, Vingerhoets, Claudia, Díaz-Caneja, Covadonga M, Ayora, Miriam, Janssen, Joost, Rodríguez-Jiménez, Roberto, Díaz-Marsá, Marina, Falkenberg, Irina, Bitsch, Florian, Berger, Philipp, Sommer, Jen, Raab, Kyeon, Jakobi, Babette, Mcgorry, Patrick, Amminger, Paul, Mchugh, Meredith, Mucci, Armida, Bucci, Paola, Piegari, Giuseppe, Pietrafesa, Daria, Nicita, Alessia, Patriarca, Sara, Zugman, André, Gadelha, Ary, Rodrigues da Cunha, Graccielle, Soo Kwon, Jun, Kevin Cho, Kang I k, Young Lee, Tae, Kim, Minah, Bin Kwak, Yoo, Jeong Hwang, Wu, Kiang, Michael, Gerritsen, Cory, Maheandiran, Margaret, Ahmed, Sarah, Prce, Ivana, Lepock, Jenny, Willeit, Matthäu, Lenczowski, Marzena, Sauerzopf, Ullrich, Weidenauer, Ana, Furtner-Srajer, Julia, Kirschner, Matthia, Burrer, Achim, Stämpfli, Philipp, Huber, Naemi, Kaiser, Stefan, Kawohl, Wolfram, Brammer, Michael, Young, Jonathan, Bullmore, Edward, Morgan, Sarah, Adult Psychiatry, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, and MUMC+: MA Med Staf Spec Psychiatrie (9)
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Research design ,MathematicsofComputing_GENERAL ,Disease ,psychosi ,DISEASE ,2738 Psychiatry and Mental Health ,0302 clinical medicine ,ultra-high-risk ,SCHIZOPHRENIA ,Multicenter Studies as Topic ,Longitudinal Studies ,Precision Medicine ,machine ,pattern-classification ,TheoryofComputation_GENERAL ,Cognition ,3. Good health ,Psychiatry and Mental health ,Research Design ,Schizophrenia ,First episode of psychosis ,PSYSCAN ,Clinical psychology ,MRI ,clinical high risk of psychosis ,first episode of psychosis ,machine learning ,neuroimaging ,prediction ,psychosis ,Psychosis ,onset ,610 Medicine & health ,Neuroimaging ,Clinical high risk of psychosis ,03 medical and health sciences ,1st-episode psychosis ,Machine learning ,medicine ,Humans ,clinical high risk of psychosi ,neuroanatomical abnormalities ,first episode of psychosi ,Protocol (science) ,reliability ,business.industry ,prediction models ,Precision medicine ,medicine.disease ,030227 psychiatry ,Psychotic Disorders ,10054 Clinic for Psychiatry, Psychotherapy, and Psychosomatics ,business ,Prediction ,030217 neurology & neurosurgery ,Regular Articles - Abstract
PSYSCAN Consortium., In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of psychosis in the hope that these could aid the prediction of onset and clinical outcome. Despite advancements in the field, neuroimaging has yet to deliver. This is in part explained by the use of univariate analytical techniques, small samples and lack of statistical power, lack of external validation of potential biomarkers, and lack of integration of nonimaging measures (eg, genetic, clinical, cognitive data). PSYSCAN is an international, longitudinal, multicenter study on the early stages of psychosis which uses machine learning techniques to analyze imaging, clinical, cognitive, and biological data with the aim of facilitating the prediction of psychosis onset and outcome. In this article, we provide an overview of the PSYSCAN protocol and we discuss benefits and methodological challenges of large multicenter studies that employ neuroimaging measures., The PSYSCAN Project is supported by grant agreement no. 603196 under the European Union’s Seventh Framework Programme.
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- 2020