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7,100 results on '"Nursing"'

1. Incidence and management of acute otitis media in adults: a primary care-based cohort study

Author

Infection & Immunity, HAG Infectieziekten, Huisartsopleiding, Epi Infectieziekten Team 1, Child Health, General Practice & Nursing Science, JC onderzoeksprogramma Infectieziekten, Rijk, Merijn H, Hullegie, Saskia, Schilder, Anne G M, Kortekaas, Marlous F, Damoiseaux, Roger A M J, Verheij, Theo J M, Venekamp, Roderick P, Infection & Immunity, HAG Infectieziekten, Huisartsopleiding, Epi Infectieziekten Team 1, Child Health, General Practice & Nursing Science, JC onderzoeksprogramma Infectieziekten, Rijk, Merijn H, Hullegie, Saskia, Schilder, Anne G M, Kortekaas, Marlous F, Damoiseaux, Roger A M J, Verheij, Theo J M, and Venekamp, Roderick P

Published
2021

2. Uptake and detection rate of a stepwise cardiometabolic disease detection program in primary care - A cohort study

Author

HAG Zorginnovatieonderzoek, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Julius Centrum, Child Health, Cancer, JC Overig onderzoek, General Practice & Nursing Science, Stol, Daphne M., Hollander, Monika, Badenbroek, Ilse F., Nielen, Mark M.J., Schellevis, François G., De Wit, Niek J., HAG Zorginnovatieonderzoek, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Julius Centrum, Child Health, Cancer, JC Overig onderzoek, General Practice & Nursing Science, Stol, Daphne M., Hollander, Monika, Badenbroek, Ilse F., Nielen, Mark M.J., Schellevis, François G., and De Wit, Niek J.

Published
2020

3. Chest discomfort at night and risk of acute coronary syndrome: cross-sectional study of telephone conversations

Author

HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, HAG Zorginnovatieonderzoek, Huisartsopleiding, Child Health, Infection & Immunity, Directie Raad van Bestuur, Wouters, Loes T, Zwart, Dorien L, Erkelens, Daphne C, Cheung, Noël S, de Groot, Esther, Damoiseaux, Roger A, Hoes, Arno W, Rutten, Frans H, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, HAG Zorginnovatieonderzoek, Huisartsopleiding, Child Health, Infection & Immunity, Directie Raad van Bestuur, Wouters, Loes T, Zwart, Dorien L, Erkelens, Daphne C, Cheung, Noël S, de Groot, Esther, Damoiseaux, Roger A, Hoes, Arno W, and Rutten, Frans H

Published
2020

4. Non-dispensing pharmacists' actions and solutions of drug therapy problems among elderly polypharmacy patients in primary care

Author

Curr. Onderwijs Huisartsgeneeskunde, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, Divisieleiding, HAG Zorginnovatieonderzoek, Julius Centrum, Child Health, Cancer, Hazen, Ankie C. M., Utrecht, University, Poldervaart, Judith M., de Gier, Johan J., de Wit, Niek J., de Bont, Antoinette A., Bouvy, Marcel L., Curr. Onderwijs Huisartsgeneeskunde, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, Divisieleiding, HAG Zorginnovatieonderzoek, Julius Centrum, Child Health, Cancer, Hazen, Ankie C. M., Utrecht, University, Poldervaart, Judith M., de Gier, Johan J., de Wit, Niek J., de Bont, Antoinette A., and Bouvy, Marcel L.

Published
2019

5. Effectiveness of the European Society of Cardiology/Heart Failure Association website ‘heartfailurematters.org’ and an e-health adjusted care pathway in patients with stable heart failure: results of the ‘e-Vita HF’ randomized controlled trial

Author

Global Health, JC onderzoeksprogramma Methodologie, HAG Infectieziekten, Cardiologie, Circulatory Health, Team Medisch, General Practice & Nursing Science, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Epidemiology & Health Economics, HAG Hart- Vaatziekten, Wagenaar, Kim P., Broekhuizen, Berna D.L., Jaarsma, Tiny, Kok, Ilse, Mosterd, Arend, Willems, Frank F., Linssen, Gerard C.M., Agema, Willem R.P., Anneveldt, Sander, Lucas, Carolien M.H.B., Mannaerts, Herman F.J., Wajon, Elly M.C.J., Dickstein, Kenneth, Cramer, Maarten J., Landman, Marcel A.J., Hoes, Arno W., Rutten, Frans H., Global Health, JC onderzoeksprogramma Methodologie, HAG Infectieziekten, Cardiologie, Circulatory Health, Team Medisch, General Practice & Nursing Science, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Epidemiology & Health Economics, HAG Hart- Vaatziekten, Wagenaar, Kim P., Broekhuizen, Berna D.L., Jaarsma, Tiny, Kok, Ilse, Mosterd, Arend, Willems, Frank F., Linssen, Gerard C.M., Agema, Willem R.P., Anneveldt, Sander, Lucas, Carolien M.H.B., Mannaerts, Herman F.J., Wajon, Elly M.C.J., Dickstein, Kenneth, Cramer, Maarten J., Landman, Marcel A.J., Hoes, Arno W., and Rutten, Frans H.

Published
2019

6. Mid-regional pro-atrial natriuretic peptide for the early detection of non-acute heart failure

Author

UMC Utrecht, Experimentele Afd. Cardiologie 1, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Gohar, Aisha, Rutten, Frans H., den Ruijter, Hester, Kelder, Johannes C., von Haehling, Stephan, Anker, Stefan D., Möckel, Martin, Hoes, Arno W., UMC Utrecht, Experimentele Afd. Cardiologie 1, HAG Hart- Vaatziekten, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Gohar, Aisha, Rutten, Frans H., den Ruijter, Hester, Kelder, Johannes C., von Haehling, Stephan, Anker, Stefan D., Möckel, Martin, and Hoes, Arno W.

Published
2019

7. Burden of disease in children with respiratory tract infections in primary care: diary-based cohort study.

Author

HAG Infectieziekten, Infection & Immunity, Epi Infectieziekten Team 1, JC onderzoeksprogramma Infectieziekten, Julius Centrum, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, Schot, M. J. C., Dekker, A. R. J., van Werkhoven, C. H., van der Velden, A. W., Cals, J. W. L., Broekhuizen, B. D. L., Hopstaken, R. M., de Wit, N. J., Verheij, T. J. M., HAG Infectieziekten, Infection & Immunity, Epi Infectieziekten Team 1, JC onderzoeksprogramma Infectieziekten, Julius Centrum, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, Schot, M. J. C., Dekker, A. R. J., van Werkhoven, C. H., van der Velden, A. W., Cals, J. W. L., Broekhuizen, B. D. L., Hopstaken, R. M., de Wit, N. J., and Verheij, T. J. M.

Published
2019

8. Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records

Author

UMC Utrecht, Cardiovasculaire Epi Team 9, Cardiologie, Onderzoek Precision medicine, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Team Medisch, Uijl, Alicia, Koudstaal, Stefan, Direk, Kenan, Denaxas, Spiros, Groenwold, Rolf H.H., Banerjee, Amitava, Hoes, Arno W., Hemingway, Harry, Asselbergs, Folkert W., UMC Utrecht, Cardiovasculaire Epi Team 9, Cardiologie, Onderzoek Precision medicine, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Team Medisch, Uijl, Alicia, Koudstaal, Stefan, Direk, Kenan, Denaxas, Spiros, Groenwold, Rolf H.H., Banerjee, Amitava, Hoes, Arno W., Hemingway, Harry, and Asselbergs, Folkert W.

Published
2019

9. Antibiotic treatment of gastroenteritis in primary care

Author

HAG Zorginnovatieonderzoek, Other research (not in main researchprogram), MMB Infectiepreventie, Epi Infectieziekten Team 1, Child Health, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Epi Infectieziekten, MMB, General Practice & Nursing Science, Cancer, JC Overig onderzoek, Schierenberg, Alwin, Bruijning-Verhagen, Patricia C.J., van Delft, Sanne, Bonten, Marc J.M., de Wit, Niek J., HAG Zorginnovatieonderzoek, Other research (not in main researchprogram), MMB Infectiepreventie, Epi Infectieziekten Team 1, Child Health, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Epi Infectieziekten, MMB, General Practice & Nursing Science, Cancer, JC Overig onderzoek, Schierenberg, Alwin, Bruijning-Verhagen, Patricia C.J., van Delft, Sanne, Bonten, Marc J.M., and de Wit, Niek J.

Published
2019

10. Selective prevention of cardiometabolic diseases: activities and attitudes of general practitioners across Europe

Author

Huisartsopleiding Opleiders, UMC Utrecht, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, de Waard, Anne Karien M., Hollander, Monika, Korevaar, Joke C., Nielen, Mark M.J., Carlsson, Axel C., Lionis, Christos, Seifert, Bohumil, Thilsing, Trine, de Wit, Niek J., Schellevis, François G., SPIMEU Project Group, Huisartsopleiding Opleiders, UMC Utrecht, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, de Waard, Anne Karien M., Hollander, Monika, Korevaar, Joke C., Nielen, Mark M.J., Carlsson, Axel C., Lionis, Christos, Seifert, Bohumil, Thilsing, Trine, de Wit, Niek J., Schellevis, François G., and SPIMEU Project Group

Published
2019

11. Barriers and facilitators among health professionals in primary care to prevention of cardiometabolic diseases: A systematic review

Author

HAG Onderzoek, HAG Zorginnovatieonderzoek, Child Health, Cancer, JC Overig onderzoek, General Practice & Nursing Science, Wändell, Per E., De Waard, Anne Karien M., Holzmann, Martin J., Gornitzki, Carl, Lionis, Christos, De Wit, Niek, Søndergaard, Jens, Sønderlund, Anders L., Kral, Norbert, Seifert, Bohumil, Korevaar, Joke C., Schellevis, François G., Carlsson, Axel C., HAG Onderzoek, HAG Zorginnovatieonderzoek, Child Health, Cancer, JC Overig onderzoek, General Practice & Nursing Science, Wändell, Per E., De Waard, Anne Karien M., Holzmann, Martin J., Gornitzki, Carl, Lionis, Christos, De Wit, Niek, Søndergaard, Jens, Sønderlund, Anders L., Kral, Norbert, Seifert, Bohumil, Korevaar, Joke C., Schellevis, François G., and Carlsson, Axel C.

Published
2018

12. Effectiveness and cost-effectiveness of proactive and multidisciplinary integrated care for older people with complex problems in general practice: an individual participant data meta-analysis

Author

Verplegingswetenschap, Infection & Immunity, Unit Opleiding Aios, Medische staf Anesthesiologie, HAG Netwerken, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, Blom, J. W., Van den Hout, W. B., Den Elzen, W. P. J., Drewes, Y. M., Bleijenberg, N., Fabbricotti, I. N., Jansen, A. P. D., Kempen, G. I. J. M., Koopmans, R., Looman, W. M., Melis, R. J. F., Metzelthin, S. F., van Charante, E. P. Moll, Muntinga, M. E., Numans, M. E., Ruikes, F. G. H., Spoorenberg, S. L. W., Stijnen, T., Suijker, J. J., De Wit, N. J., Wynia, K., Wind, A. W., Gussekloo, J., Verplegingswetenschap, Infection & Immunity, Unit Opleiding Aios, Medische staf Anesthesiologie, HAG Netwerken, General Practice & Nursing Science, Child Health, Cancer, JC Overig onderzoek, Blom, J. W., Van den Hout, W. B., Den Elzen, W. P. J., Drewes, Y. M., Bleijenberg, N., Fabbricotti, I. N., Jansen, A. P. D., Kempen, G. I. J. M., Koopmans, R., Looman, W. M., Melis, R. J. F., Metzelthin, S. F., van Charante, E. P. Moll, Muntinga, M. E., Numans, M. E., Ruikes, F. G. H., Spoorenberg, S. L. W., Stijnen, T., Suijker, J. J., De Wit, N. J., Wynia, K., Wind, A. W., and Gussekloo, J.

Published
2018

13. Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology

Author

Epidemiology & Health Economics, General Practice & Nursing Science, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Seferović, Petar M., Petrie, Mark C., Filippatos, Gerasimos S., Anker, Stefan D., Rosano, Giuseppe, Bauersachs, Johann, Paulus, Walter J., Komajda, Michel, Cosentino, Francesco, de Boer, Rudolf A., Farmakis, Dimitrios, Doehner, Wolfram, Lambrinou, Ekaterini, Lopatin, Yuri, Piepoli, Massimo F., Theodorakis, Michael J., Wiggers, Henrik, Lekakis, John, Mebazaa, Alexandre, Mamas, Mamas A., Tschöpe, Carsten, Hoes, Arno W., Seferović, Jelena P., Logue, Jennifer, McDonagh, Theresa, Riley, Jillian P., Milinković, Ivan, Polovina, Marija, van Veldhuisen, Dirk J., Lainscak, Mitja, Maggioni, Aldo P., Ruschitzka, Frank, McMurray, John J.V., Epidemiology & Health Economics, General Practice & Nursing Science, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Seferović, Petar M., Petrie, Mark C., Filippatos, Gerasimos S., Anker, Stefan D., Rosano, Giuseppe, Bauersachs, Johann, Paulus, Walter J., Komajda, Michel, Cosentino, Francesco, de Boer, Rudolf A., Farmakis, Dimitrios, Doehner, Wolfram, Lambrinou, Ekaterini, Lopatin, Yuri, Piepoli, Massimo F., Theodorakis, Michael J., Wiggers, Henrik, Lekakis, John, Mebazaa, Alexandre, Mamas, Mamas A., Tschöpe, Carsten, Hoes, Arno W., Seferović, Jelena P., Logue, Jennifer, McDonagh, Theresa, Riley, Jillian P., Milinković, Ivan, Polovina, Marija, van Veldhuisen, Dirk J., Lainscak, Mitja, Maggioni, Aldo P., Ruschitzka, Frank, and McMurray, John J.V.

Published
2018

14. Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people

Author

Cardiovasculaire Immunologie, UMC Utrecht, Arts Assistenten Cardiologie, Onderzoek Precision medicine, Regenerative Medicine and Stem Cells, Epidemiology & Health Economics, General Practice & Nursing Science, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Team Medisch, Koudstaal, Stefan, Pujades-Rodriguez, Mar, Denaxas, Spiros C, Gho, Johannes M.I.H., Shah, Anoop D, Yu, Ning, Patel, Riyaz S, Gale, Chris P, Hoes, Arno W., Cleland, John G F, Asselbergs, Folkert W., Hemingway, Harry, Cardiovasculaire Immunologie, UMC Utrecht, Arts Assistenten Cardiologie, Onderzoek Precision medicine, Regenerative Medicine and Stem Cells, Epidemiology & Health Economics, General Practice & Nursing Science, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Team Medisch, Koudstaal, Stefan, Pujades-Rodriguez, Mar, Denaxas, Spiros C, Gho, Johannes M.I.H., Shah, Anoop D, Yu, Ning, Patel, Riyaz S, Gale, Chris P, Hoes, Arno W., Cleland, John G F, Asselbergs, Folkert W., and Hemingway, Harry

Published
2017

15. Guideline adherence for diagnostic faeces testing in primary care patients with gastroenteritis

Author

HAG Zorginnovatieonderzoek, JC onderzoeksprogramma Infectieziekten, Other research (not in main researchprogram), HAG Infectieziekten, Infection & Immunity, MMB opleiding Arts microbioloog, Epi Infectieziekten Team 1, Child Health, HAG Child Health, Epi Infectieziekten, MMB, General Practice & Nursing Science, Cancer, JC Overig onderzoek, Schierenberg, Alwin, Broekhuizen, Berna D L, Nipshagen, Martine D, Kommer, Maarten B J, Bruijning-Verhagen, Patricia C J, van Delft, Sanne, van de Pol, Alma C, Bonten, Marc J M, de Wit, Niek J, HAG Zorginnovatieonderzoek, JC onderzoeksprogramma Infectieziekten, Other research (not in main researchprogram), HAG Infectieziekten, Infection & Immunity, MMB opleiding Arts microbioloog, Epi Infectieziekten Team 1, Child Health, HAG Child Health, Epi Infectieziekten, MMB, General Practice & Nursing Science, Cancer, JC Overig onderzoek, Schierenberg, Alwin, Broekhuizen, Berna D L, Nipshagen, Martine D, Kommer, Maarten B J, Bruijning-Verhagen, Patricia C J, van Delft, Sanne, van de Pol, Alma C, Bonten, Marc J M, and de Wit, Niek J

Published
2017

16. C-reactive protein point-of-care testing and associated antibiotic prescribing

Author

HAG Onderzoek, HAG Child Health, JC onderzoeksprogramma Infectieziekten, Infection & Immunity, HAG Infectieziekten, General Practice & Nursing Science, Cancer, Brain, JC Overig onderzoek, Child Health, Minnaard, Margaretha C., van de Pol, Alma C., Hopstaken, Rogier M., van Delft, Sanne, Broekhuizen, Berna D. L., Verheij, Theo J. M., de Wit, Niek J., HAG Onderzoek, HAG Child Health, JC onderzoeksprogramma Infectieziekten, Infection & Immunity, HAG Infectieziekten, General Practice & Nursing Science, Cancer, Brain, JC Overig onderzoek, Child Health, Minnaard, Margaretha C., van de Pol, Alma C., Hopstaken, Rogier M., van Delft, Sanne, Broekhuizen, Berna D. L., Verheij, Theo J. M., and de Wit, Niek J.

Published
2016

17. Development and validation of a new instrument measuring guideline adherence in clinical practice

Author

HAG Child Health, Huisartsopleiding, JC Overig onderzoek, Circulatory Health, Epi Methoden Team 1, Epidemiology & Health Economics, Brain, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Cancer, Child Health, Kortekaas, Marlous F., Bartelink, Marie-Louise E. L., van der Heijden, Geert J. M. G., Hoes, Arno W., de Wit, Niek J., HAG Child Health, Huisartsopleiding, JC Overig onderzoek, Circulatory Health, Epi Methoden Team 1, Epidemiology & Health Economics, Brain, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Cancer, Child Health, Kortekaas, Marlous F., Bartelink, Marie-Louise E. L., van der Heijden, Geert J. M. G., Hoes, Arno W., and de Wit, Niek J.

Published
2016

18. Improving usual care after sudden death in the young with focus on inherited cardiac diseases (the CAREFUL study): A community-based intervention study

Author

Aios en Stafsecr. Cardiologie, General Practice & Nursing Science, Other research (not in main researchprogram), Genetica, Geboortecentrum voorzitterschap, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Pathologie patiënten zorg, Regenerative Medicine and Stem Cells, DHS-Medisch, Cardiovasculaire Immunologie, Van Der Werf, Christian, Hendrix, Anneke, Birnie, Erwin, Bots, Michiel L., Vink, Aryan, Bardai, Abdennasser, Blom, Marieke T., Bosch, Jan, Bruins, Wendy, Das, C., Koster, Rudolph W., Naujocks, Tatjana, Schaap, Balthasar, Tan, Hanno L., De Vos, Ronald, De Vries, Philip, Woonink, Frits, Doevendans, Pieter A., Van Weert, Henk C., Wilde, Arthur A M, Mosterd, Arend, Van Langen, Irene M., Aios en Stafsecr. Cardiologie, General Practice & Nursing Science, Other research (not in main researchprogram), Genetica, Geboortecentrum voorzitterschap, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Pathologie patiënten zorg, Regenerative Medicine and Stem Cells, DHS-Medisch, Cardiovasculaire Immunologie, Van Der Werf, Christian, Hendrix, Anneke, Birnie, Erwin, Bots, Michiel L., Vink, Aryan, Bardai, Abdennasser, Blom, Marieke T., Bosch, Jan, Bruins, Wendy, Das, C., Koster, Rudolph W., Naujocks, Tatjana, Schaap, Balthasar, Tan, Hanno L., De Vos, Ronald, De Vries, Philip, Woonink, Frits, Doevendans, Pieter A., Van Weert, Henk C., Wilde, Arthur A M, Mosterd, Arend, and Van Langen, Irene M.

Published
2016

19. Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care

Author

HAG Zorginnovatieonderzoek, Cancer, HAG Infectieziekten, JC onderzoeksprogramma Infectieziekten, Infection & Immunity, Biostatistiek Onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, de Vries-van Vugt, Saskia F., Broekhuizen, Berna D L, Zuithoff, Nicolaas P A, van Essen, Gerrit A., Ebell, Mark H., Coenen, Samuel, Ieven, Margareta, Lammens, Christine, Goossens, Herman, Butler, Chris C., Hood, Kerenza, Littleg, Paul, Verheij, Theo J M, Zuithoff, Peter, van Essen, Ted, Almirall, Jordi, Blasi, Francesco, Chlabicz, Slawomir, Davies, Mel, Godycki-Cwirko, Maciek, Hupkova, Helena, Kersnik, Janko, Mierzecki, Artur, Mölstad, Sigvard, Moore, Michael, Schaberg, Tom, de Sutter, An, Torres, Antoni, Touboul, Pia, Little, Paul, Verheij, Theo, HAG Zorginnovatieonderzoek, Cancer, HAG Infectieziekten, JC onderzoeksprogramma Infectieziekten, Infection & Immunity, Biostatistiek Onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, de Vries-van Vugt, Saskia F., Broekhuizen, Berna D L, Zuithoff, Nicolaas P A, van Essen, Gerrit A., Ebell, Mark H., Coenen, Samuel, Ieven, Margareta, Lammens, Christine, Goossens, Herman, Butler, Chris C., Hood, Kerenza, Littleg, Paul, Verheij, Theo J M, Zuithoff, Peter, van Essen, Ted, Almirall, Jordi, Blasi, Francesco, Chlabicz, Slawomir, Davies, Mel, Godycki-Cwirko, Maciek, Hupkova, Helena, Kersnik, Janko, Mierzecki, Artur, Mölstad, Sigvard, Moore, Michael, Schaberg, Tom, de Sutter, An, Torres, Antoni, Touboul, Pia, Little, Paul, and Verheij, Theo

Published
2015

20. General practice trainees' information searching strategies for clinical queries encountered in daily practice

Author

HAG Child Health, Huisartsopleiding, JC Overig onderzoek, Circulatory Health, Epidemiology & Health Economics, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Julius Centrum, General Practice & Nursing Science, Cancer, Kortekaas, Marlous F, Bartelink, Marie-Louise E. L., Boelman, Lia, Hoes, Arno W., de Wit, NJ, HAG Child Health, Huisartsopleiding, JC Overig onderzoek, Circulatory Health, Epidemiology & Health Economics, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Julius Centrum, General Practice & Nursing Science, Cancer, Kortekaas, Marlous F, Bartelink, Marie-Louise E. L., Boelman, Lia, Hoes, Arno W., and de Wit, NJ

Published
2015

21. An exploration of beliefs and attitudes regarding healthy lifestyle behaviour in an urban population in The Netherlands: Results from a focus group study in a community-based prevention project

Author

General Practice & Nursing Science, Cancer, JC Overig onderzoek, Kloosterboer, Sanne M., van den Brekel, Karolien, Rengers, Antonia H., Peek, Niels, de Wit, NJ, General Practice & Nursing Science, Cancer, JC Overig onderzoek, Kloosterboer, Sanne M., van den Brekel, Karolien, Rengers, Antonia H., Peek, Niels, and de Wit, NJ

Published
2015

22. Corrigendum to: ‘ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 [Eur J Heart Fail 2012;14:803-869].

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, McMurray, J.J.V., Adamopoulos, S., Anker, S.D., Auricchio, A., Böhm, M., Dickstein, K., Falk, V., Filippatos, G., Fonseca, C., Gomez-Sanchez, M.A., Jaarsma, T., Køber, L., Lip, G.Y.H., Maggioni, A.P., Parkhomenko, A., Pieske, B.M., Popescu, B.A., Rønnevik, P.K., Rutten, F.H., Schwitter, J., Seferovic, P., Stepinska, J., Trindade, P.T., Voors, A.A., Zannad, F., Zeiher, A.., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, McMurray, J.J.V., Adamopoulos, S., Anker, S.D., Auricchio, A., Böhm, M., Dickstein, K., Falk, V., Filippatos, G., Fonseca, C., Gomez-Sanchez, M.A., Jaarsma, T., Køber, L., Lip, G.Y.H., Maggioni, A.P., Parkhomenko, A., Pieske, B.M., Popescu, B.A., Rønnevik, P.K., Rutten, F.H., Schwitter, J., Seferovic, P., Stepinska, J., Trindade, P.T., Voors, A.A., Zannad, F., and Zeiher, A..

Published
2013

23. Primary care clinicians' perceptions of antibiotic resistance: a multi-country qualitative interview study.

Author

Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Wood, F., Philips, C., Brookes-Howell, L., Hood, K., Verheij, Th.J.M., Coenen, S., Little, P., Melbye, H., Godycki-Cwirko, M., Jakobsen, K., Worby, P., Goossens, H., Butler, C.C., Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Wood, F., Philips, C., Brookes-Howell, L., Hood, K., Verheij, Th.J.M., Coenen, S., Little, P., Melbye, H., Godycki-Cwirko, M., Jakobsen, K., Worby, P., Goossens, H., and Butler, C.C.

Published
2013

24. Discrepancies between guidelines and clinical practice regarding prostate-specific antigen testing

Author

JC onderzoeksprogramma Infectieziekten, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, Epidemiology & Health Economics, Hamoen, E.H., Reukers, D.F., Numans, M.E., Barentsz, J.O., Witjes, J.A., Rovers, M.M., JC onderzoeksprogramma Infectieziekten, JC Overig onderzoek, Other research (not in main researchprogram), General Practice & Nursing Science, Epidemiology & Health Economics, Hamoen, E.H., Reukers, D.F., Numans, M.E., Barentsz, J.O., Witjes, J.A., and Rovers, M.M.

Published
2013

25. Strategies to promote prudent antibiotic use: exploring the views of professionals who develop and implement guidelines and interventions

Author

Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Tonkin-Crine, S., Yardley, L., Coenen, S., Fernandez-Vandellos, P., Krawczyk, J., Touboul, P., Verheij, Th.J.M., Little, P., Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Tonkin-Crine, S., Yardley, L., Coenen, S., Fernandez-Vandellos, P., Krawczyk, J., Touboul, P., Verheij, Th.J.M., and Little, P.

Published
2013

26. Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Author

JC Overig onderzoek, Other research (not in main researchprogram), Cancer, MS MDL 1, General Practice & Nursing Science, Pathologie, Agudo, A, Bonet, C., et al, X, Bueno de Mesquita, H.B., Siersema, P.D., Numans, M.E., Offerhaus, G.J.A., Jakszyn, P., JC Overig onderzoek, Other research (not in main researchprogram), Cancer, MS MDL 1, General Practice & Nursing Science, Pathologie, Agudo, A, Bonet, C., et al, X, Bueno de Mesquita, H.B., Siersema, P.D., Numans, M.E., Offerhaus, G.J.A., and Jakszyn, P.

Published
2013

27. Risk of recurrent acute lower urinary tract infections and prescription pattern of antibiotics in women with and without diabetes in primary care

Author

Circulatory Health, Infection & Immunity, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, Other research (not in main researchprogram), General Practice & Nursing Science, Data Science & Biostatistiek, MS Infectieziekten, Gorter, K.J., Hak, E., Zuithoff, N.P.A., Hoepelman, A.I.M., Rutten, G.E.H.M., Circulatory Health, Infection & Immunity, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, Other research (not in main researchprogram), General Practice & Nursing Science, Data Science & Biostatistiek, MS Infectieziekten, Gorter, K.J., Hak, E., Zuithoff, N.P.A., Hoepelman, A.I.M., and Rutten, G.E.H.M.

Published
2010

28. A clinical prediction rule for detecting major depressive disorder in primary care:the PREDICT-NL study

Author

Infection & Immunity, JC onderzoeksprogramma Methodologie, Data Science & Biostatistiek, Epidemiology & Health Economics, General Practice & Nursing Science, Cluster B, Zuithoff, N.P.A., Vergouwe, Y., King, M., Nazareth, I., Hak, E., Moons, K.G.M., Geerlings, M.I., Infection & Immunity, JC onderzoeksprogramma Methodologie, Data Science & Biostatistiek, Epidemiology & Health Economics, General Practice & Nursing Science, Cluster B, Zuithoff, N.P.A., Vergouwe, Y., King, M., Nazareth, I., Hak, E., Moons, K.G.M., and Geerlings, M.I.

Published
2009

29. Clinically relevant diagnostic research in primary care: the example of B-type natriuretic peptides in the detection of heart failure

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Epidemiology & Health Economics, Kelder, J.C., Rutten, F.H., Hoes, A.W., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Epidemiology & Health Economics, Kelder, J.C., Rutten, F.H., and Hoes, A.W.

Published
2009

30. The diagnostic value of history and physical examination for COPD in suspected or known cases: a systematic review

Author

Infection & Immunity, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Epidemiology & Health Economics, Anesthesiologie, Kwaliteit en Patiëntveiligheid, Broekhuizen, B.D.L., Sachs, A.P.E., Oostvogels, R., Hoes, A.W., Verheij, Th.J.M., Moons, K.G.M., Infection & Immunity, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Epidemiology & Health Economics, Anesthesiologie, Kwaliteit en Patiëntveiligheid, Broekhuizen, B.D.L., Sachs, A.P.E., Oostvogels, R., Hoes, A.W., Verheij, Th.J.M., and Moons, K.G.M.

Published
2009

31. Palliative care in heart failure: a position statement from the palliative care workshop of the Heart Failure Association of the European Society of Cardiology

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Jaarsma, T., Beattie, J.M., Ryder, M., Rutten, F.H., McDonagh, T., Mohasci, P., Murray, S.A., Grodzicki, T., Bergh, I., Metra, M., Ekman, I., Angermann, C.E., Leventhal, M., Pitsis, A., Anker, S.D., Gavazzi, A., Ponikowski, P., Dickstein, K., Delacretaz, E., Blue, L., Strasser, F., McMurray, J.J., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Jaarsma, T., Beattie, J.M., Ryder, M., Rutten, F.H., McDonagh, T., Mohasci, P., Murray, S.A., Grodzicki, T., Bergh, I., Metra, M., Ekman, I., Angermann, C.E., Leventhal, M., Pitsis, A., Anker, S.D., Gavazzi, A., Ponikowski, P., Dickstein, K., Delacretaz, E., Blue, L., Strasser, F., and McMurray, J.J.

Published
2009

32. Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children

Author

Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Zorgeenheid KNO Medisch, Cluster B, Zorgeenheid Traumatologie, General Practice & Nursing Science, Epidemiology & Health Economics, MMB, van der Veen, E.L., Schilder, A.G.M., Timmers, T.K., Rovers, M.M., Fluit, A.C., Bonten, M.J.M., Leverstein-van Hall, M.A., Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Zorgeenheid KNO Medisch, Cluster B, Zorgeenheid Traumatologie, General Practice & Nursing Science, Epidemiology & Health Economics, MMB, van der Veen, E.L., Schilder, A.G.M., Timmers, T.K., Rovers, M.M., Fluit, A.C., Bonten, M.J.M., and Leverstein-van Hall, M.A.

Published
2009

33. Invasive pneumococcal disease among adults: associations among serotypes, disease characteristics, and outcome.

Author

Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Cluster B, Immunologie/Reumatologie, Epidemiology & Health Economics, Jansen, A.G.S.C., Rodenburg, G.D., van der Ende, A., van Alphen, L., Veenhoven, R.H., Spanjaard, L., Sanders, E.A.M., Hak, E., Infection & Immunity, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, Cluster B, Immunologie/Reumatologie, Epidemiology & Health Economics, Jansen, A.G.S.C., Rodenburg, G.D., van der Ende, A., van Alphen, L., Veenhoven, R.H., Spanjaard, L., Sanders, E.A.M., and Hak, E.

Published
2009

34. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC).

Author

JC onderzoeksprogramma Kanker, Epidemiology & Health Economics, General Practice & Nursing Science, Gonzalez, C.A., Jakszyn, P., Pera, G., Agudo, A., Bingham, S, Palli, D., Ferrari, P., Boeing, H.H., del Giudice, G., Plebani, M., Carneiro, F., Nesi, G., Berrino, F., Sacerdote, C., Tumino, R., Panico, S., Berglund, G., Siman, H., Nyren, O., Hallmans, G., Martinez, C., Dorronsoro, M., Barricarte, A., Navarro, C., Quiros, J.R., Allen, N., Key, T.J., Day, N.E., Linseisen, J., Nagel, G., Bergmann, M.M., Overvad, K., Jensen, M.K., Tjonneland, A., Olsen, A., Bueno de Mesquita, H.B., Ocke, M.C., Peeters, P.H.M., Numans, M.E., Clavel-Chapelon, F., Boutron-Ruault, M.C., Trichopoulou, A., Psaltopoulou, T., Roukos, D., Lund, E., Hemon, B., Kaaks, R., Norat, T., Riboli, E., JC onderzoeksprogramma Kanker, Epidemiology & Health Economics, General Practice & Nursing Science, Gonzalez, C.A., Jakszyn, P., Pera, G., Agudo, A., Bingham, S, Palli, D., Ferrari, P., Boeing, H.H., del Giudice, G., Plebani, M., Carneiro, F., Nesi, G., Berrino, F., Sacerdote, C., Tumino, R., Panico, S., Berglund, G., Siman, H., Nyren, O., Hallmans, G., Martinez, C., Dorronsoro, M., Barricarte, A., Navarro, C., Quiros, J.R., Allen, N., Key, T.J., Day, N.E., Linseisen, J., Nagel, G., Bergmann, M.M., Overvad, K., Jensen, M.K., Tjonneland, A., Olsen, A., Bueno de Mesquita, H.B., Ocke, M.C., Peeters, P.H.M., Numans, M.E., Clavel-Chapelon, F., Boutron-Ruault, M.C., Trichopoulou, A., Psaltopoulou, T., Roukos, D., Lund, E., Hemon, B., Kaaks, R., Norat, T., and Riboli, E.

Published
2006

38. Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary. disease

Author

JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Cardiologie, Epidemiology & Health Economics, Longziekten, Rutten, F.H., Cramer, M.J.M., Grobbee, D.E., Sachs, A.P.E., Kirkels, J.H., Lammers, J.W.J., Hoes, A.W., JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Cardiologie, Epidemiology & Health Economics, Longziekten, Rutten, F.H., Cramer, M.J.M., Grobbee, D.E., Sachs, A.P.E., Kirkels, J.H., Lammers, J.W.J., and Hoes, A.W.

Published
2005

41. Cross-Cultural Equivalence of de Jong Gierveld Loneliness Scale among Older Native and Diasporic Chinese Adults

Author

Cees P. van der Schans, Hans Hobbelen, Wim P. Krijnen, Sie-Long Cheung, Governance and Pluralism, and Healthy Ageing, Allied Health Care and Nursing

Subjects
Research design, Cross-Cultural Comparison, China, Psychometrics, psychometric properties, behavioral disciplines and activities, Cronbach's alpha, Goodness of fit, SDG 3 - Good Health and Well-being, Surveys and Questionnaires, Item response theory, medicine, Humans, Equivalence (measure theory), Aged, Loneliness, item response theory, Reproducibility of Results, General Medicine, Mental health, Confirmatory factor analysis, gerontologie, cross-national comparison, Geriatrics and Gerontology, medicine.symptom, Psychology, Gerontology, mental health, Clinical psychology
Abstract

BACKGROUND AND OBJECTIVES: Loneliness is prevalent among older adults and known to be detrimental to mental health. The objective of this study was to determine the psychometric properties of the Chinese 6-item De Jong Gierveld Loneliness Scale (DJGLS) in the older native and diasporic Chinese community. RESEARCH DESIGN AND METHODS: Participants were recruited from a local community in urban Tianjin, China and urban Chinese communities of older adults in the Netherlands. Scale properties, including reliability, were calculated with Cronbach's alpha and multiple-group confirmatory factor analysis to examine the two-dimensional structure of the scale and the cross-cultural equivalence between both countries. Item response analysis was employed to plot the relationships between the item response and expected total scale score. RESULTS: A total of 193 older adults from China and 135 older adults from the Netherlands were included. The Cronbach's alphas were and 0.68 (China) and 0.71 (the Netherlands). The DJGLS's two-dimensional structure was validated by the goodness of fit and the factor loadings. Cross-cultural equivalence was demonstrated with the multiple-group confirmatory analysis. In addition, sufficient discriminative power of the individual items was demonstrated by item response analysis in both countries. DISCUSSION AND IMPLICATIONS: This study is the first to provide a detailed item behavior analysis with an item response analysis of the DJGLS. In conclusion, the findings of this study suggest that the DJGLS has adequate and similar item and scalar equivalence for use in Chinese populations.;BACKGROUND AND OBJECTIVESLoneliness is prevalent among older adults and known to be detrimental to mental health. The objective of this study was to determine the psychometric properties of the Chinese 6-item De Jong Gierveld Loneliness Scale (DJGLS) in the older native and diasporic Chinese community. RESEARCH DESIGN AND METHODSParticipants were recruited from a local community in urban Tianjin, China and urban Chinese communities of older adults in the Netherlands. Scale properties, including reliability, were calculated with Cronbach's alpha and multiple-group confirmatory factor analysis to examine the two-dimensional structure of the scale and the cross-cultural equivalence between both countries. Item response analysis was employed to plot the relationships between the item response and expected total scale score. RESULTSA total of 193 older adults from China and 135 older adults from the Netherlands were included. The Cronbach's alphas were and 0.68 (China) and 0.71 (the Netherlands). The DJGLS's two-dimensional structure was validated by the goodness of fit and the factor loadings. Cross-cultural equivalence was demonstrated with the multiple-group confirmatory analysis. In addition, sufficient discriminative power of the individual items was demonstrated by item response analysis in both countries. DISCUSSION AND IMPLICATIONSThis study is the first to provide a detailed item behavior analysis with an item response analysis of the DJGLS. In conclusion, the findings of this study suggest that the DJGLS has adequate and similar item and scalar equivalence for use in Chinese populations.

Published
2022

42. The nurse-coordinated cardiac care bridge transitional care programme: a randomised clinical trial

Author

Jill Dekker, Patricia Jepma, Sara Daliri, Lotte Verweij, Su-San Liem, Fatma Karapinar-Çarkit, Corine H.M. Latour, José L. Klunder, Wilma Scholte op Reimer, Bianca M. Buurman, Michel S. Terbraak, Ron J.G. Peters, Gerben ter Riet, Arno H.M. Moons, University of Zurich, Jepma, Patricia, Cardiology, VU University medical center, ACS - Atherosclerosis & ischemic syndromes, Nursing, Geriatrics, APH - Aging & Later Life, APH - Quality of Care, Pharmacy, APH - Personalized Medicine, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, Faculteit Gezondheid, Urban Vitality, Lectoraat Integratie van Psychiatrische en Somatische Zorg, and Lectoraat Acute Ouderenzorg

Subjects
medicine.medical_specialty, Aging, medicine.medical_treatment, Pharmacist, 11549 Institute of Implementation Science in Health Care, Aftercare, ageing/3, 610 Medicine & health, 2717 Geriatrics and Gerontology, ageing/5, 030204 cardiovascular system & hematology, Patient Readmission, AcademicSubjects/MED00280, 03 medical and health sciences, 0302 clinical medicine, 1302 Aging, Humans, Medicine, case management, Single-Blind Method, Transitional care, 030212 general & internal medicine, Disease management (health), Aged, Aged, 80 and over, Rehabilitation, business.industry, transitional care, General Medicine, Patient Discharge, Integrated care, Clinical trial, cardiac rehabilitation, ageing/17, disease management, Cardiac Care Facilities, Relative risk, cardiology, Emergency medicine, Geriatrics and Gerontology, business, Research Paper
Abstract

Background after hospitalisation for cardiac disease, older patients are at high risk of readmission and death. Objective the cardiac care bridge (CCB) transitional care programme evaluated the impact of combining case management, disease management and home-based cardiac rehabilitation (CR) on hospital readmission and mortality. Design single-blind, randomised clinical trial. Setting the trial was conducted in six hospitals in the Netherlands between June 2017 and March 2020. Community-based nurses and physical therapists continued care post-discharge. Subjects cardiac patients ≥ 70 years were eligible if they were at high risk of functional loss or if they had had an unplanned hospital admission in the previous 6 months. Methods the intervention group received a comprehensive geriatric assessment-based integrated care plan, a face-to-face handover with the community nurse before discharge and follow-up home visits. The community nurse collaborated with a pharmacist and participants received home-based CR from a physical therapist. The primary composite outcome was first all-cause unplanned readmission or mortality at 6 months. Results in total, 306 participants were included. Mean age was 82.4 (standard deviation 6.3), 58% had heart failure and 92% were acutely hospitalised. 67% of the intervention key-elements were delivered. The composite outcome incidence was 54.2% (83/153) in the intervention group and 47.7% (73/153) in the control group (risk differences 6.5% [95% confidence intervals, CI −4.7 to 18%], risk ratios 1.14 [95% CI 0.91–1.42], P = 0.253). The study was discontinued prematurely due to implementation activities in usual care. Conclusion in high-risk older cardiac patients, the CCB programme did not reduce hospital readmission or mortality within 6 months. Trial registration Netherlands Trial Register 6,316, https://www.trialregister.nl/trial/6169

Published
2021

43. Insight Into the Posthospital Syndrome: A 3-Month Longitudinal Follow up on Geriatric Syndromes and Their Association With Functional Decline, Readmission, and Mortality

Author

Lucienne A Reichardt, Jesse J. Aarden, Martin van der Esch, Jos W. R. Twisk, Raoul H.H. Engelbert, Rosanne van Seben, Jos A. Bosch, Marike van der Schaaf, Bianca M. Buurman, Kenneth E. Covinsky, Klinische Psychologie (Psychologie, FMG), Graduate School, APH - Aging & Later Life, APH - Quality of Care, Amsterdam Neuroscience - Neuroinfection & -inflammation, Amsterdam Movement Sciences, Rehabilitation medicine, Medical Psychology, Nursing, Geriatrics, AMS - Rehabilitation & Development, AMS - Ageing & Vitality, APH - Mental Health, APH - Digital Health, Epidemiology and Data Science, APH - Health Behaviors & Chronic Diseases, APH - Methodology, Urban Vitality, and Lectoraat Interdisciplinaire Zorg voor Chronische Gewrichtsaandoeningen

Subjects
Male, Physical and Cogntive Function, Aging, Pediatrics, medicine.medical_specialty, Time Factors, Apathy, THE JOURNAL OF GERONTOLOGY: Medical Sciences, Logistic regression, Postdischarge, Patient Readmission, Fear of falling, AcademicSubjects/MED00280, Risk Factors, medicine, Humans, Cognitive Dysfunction, Longitudinal Studies, Mobility Limitation, Prospective cohort study, Acute hospitalization, Geriatric Assessment, Aged, Aged, 80 and over, Geriatrics, business.industry, Geriatric syndromes, Recovery of Function, Syndrome, Odds ratio, medicine.disease, Adverse outcomes, Confidence interval, Malnutrition, Logistic Models, AcademicSubjects/SCI00960, Female, Geriatrics and Gerontology, medicine.symptom, business, Follow-Up Studies
Abstract

Background Acute hospitalization may lead to posthospital syndrome, but no studies have investigated how this syndrome manifests and geriatric syndromes are often used as synonym. However, studies on longitudinal associations between syndromes and adverse outcomes are scarce. We aimed to analyze longitudinal associations between geriatric syndromes and functional decline (FD), readmission, and mortality. Methods Prospective cohort study, including 401 acutely hospitalized patients (aged ≥ 70). We performed: (i) logistic regression analyses to assess associations between patterns of geriatric syndromes as they develop over time (between admission and 1 month postdischarge), and FD and readmission; (ii) generalized estimating equations to assess longitudinal associations between geriatric syndromes over five time points (admission, discharge, 1, 2, and 3 months postdischarge) and FD, mortality, and readmission at 3 months postdischarge. Results After syndrome absent, syndrome present at both admission and 1 month postdischarge was most prevalent. Persistent patterns of apathy (odds ratio [OR] = 4.35, 95% confidence interval [CI] = 1.54–12.30), pain (OR = 3.26, 95% CI = 1.21–8.8), malnutrition (OR = 3.4, 95% CI = 1.35–8.56), mobility impairment (OR = 6.65, 95% CI = 1.98–22.38), and fear of falling (OR = 3.17, 95% CI = 1.25–8.02) were associated with FD. Developing cognitive impairment (OR = 6.40, 95% CI = 1.52–26.84), fatigue (OR = 4.71, 95% CI = 1.03–21.60), and fall risk (OR = 4.30, 95% CI = 1.21–16.57) postdischarge, was associated with readmission; however, only 4%–6% developed these syndromes. Over the course of five time points, mobility impairment, apathy, and incontinence were longitudinally associated with FD; apathy, malnutrition, fatigue, and fall risk with mortality; malnutrition with readmission. Conclusion Most geriatric syndromes are present at admission and patients are likely to retain them postdischarge. Several geriatric syndromes are longitudinally associated with mortality and, particularly, persistently present syndromes place persons are at risk of FD. Although few persons develop syndromes postdischarge, those developing cognitive impairment, fatigue, and fall risk were at increased readmission risk.

Published
2020

44. A genetic cluster of MDR Enterobacter cloacae complex ST78 harbouring a plasmid containing bla VIM-1 and mcr-9 in the Netherlands

Author

Hendrickx, Antoni P. A., Debast, Sylvia, Pérez-Vázquez, María, Schoffelen, Annelot F., Notermans, Daan W., Landman, Fabian, Wielders, Cornelia C. H., Cañada Garcia, Javier E., Flipse, Jacky, de Haan, Angela, Witteveen, Sandra, van Santen-Verheuvel, Marga, de Greeff, Sabine C., Kuijper, Ed, Schouls, Leo M., Maijer-Reuwer, A., Leversteijn-van Hall, M. A., Kluytmans, J. A. J. W., Spijkerman, I. J. B., van Dijk, K., Halaby, T., Zwart, B., Diederen, B. M. W., Voss, A., Dorigo-Zetsma, J. W., Ott, A., Oudbier, J. H., van der Vusse, M., Vlek, A. L. M., Buiting, A. G. M., Bode, L., Paltansing, S., van Griethuysen, A. J., den Reijer, M., van Trijp, M., van Elzakker, E. P. M., Muller, A. E., van der Linden, M. P. M., van Rijn, M., Wolfhagen, M. J. H. M., Waar, K., Kolwijck, E., Silvis, W., Schulin, T., Damen, M., Dinant, S., van Mens, S. P., Melles, D. C., Cohen Stuart, J. W. T., van Ogtrop, M. L., Overdevest, I. T. M. A., van Dam, A. P., Wertheim, H., Frénay, H. M. E., Sinnige, J. C., Mattsson, E. E., Bosboom, R. W., Stam, A., de Jong, E., Roescher, N., Heikens, E., Steingrover, R., Troelstra, A., Bathoorn, E., Trienekens, T. A. M., van Dam, D. W., de Brauwer, E. I. G. B., Stals, F. S., Government of Netherlands, Medical Microbiology and Infection Prevention, AII - Inflammatory diseases, Elderly care medicine, APH - Aging & Later Life, AII - Infectious diseases, Nursing, APH - Health Behaviors & Chronic Diseases, and Experimental Immunology

Subjects
0301 basic medicine, Carbapenem, biology, Brief Report, 030106 microbiology, Broth microdilution, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, bacterial infections and mycoses, Meropenem, Microbiology, 03 medical and health sciences, 030104 developmental biology, Plasmid, AcademicSubjects/MED00290, Colistin, medicine, Multilocus sequence typing, AcademicSubjects/MED00740, AcademicSubjects/MED00230, Enterobacter cloacae, Etest, medicine.drug
Abstract

Background Carbapenemases produced by Enterobacterales are often encoded by genes on transferable plasmids and represent a major healthcare problem, especially if the plasmids contain additional antibiotic resistance genes. As part of Dutch national surveillance, 50 medical microbiological laboratories submit their Enterobacterales isolates suspected of carbapenemase production to the National Institute for Public Health and the Environment for characterization. All isolates for which carbapenemase production is confirmed are subjected to next-generation sequencing. Objectives To study the molecular characteristics of a genetic cluster of Enterobacter cloacae complex isolates collected in Dutch national surveillance in the period 2015–20 in the Netherlands. Methods Short- and long-read genome sequencing was used in combination with MLST and pan-genome MLST (pgMLST) analyses. Automated antimicrobial susceptibility testing (AST), the Etest for meropenem and the broth microdilution test for colistin were performed. The carbapenem inactivation method was used to assess carbapenemase production. Results pgMLST revealed that nine E. cloacae complex isolates from three different hospitals in the Netherlands differed by Conclusions The EclCluster-013 reported here represents an MDR E. cloacae complex ST78 strain containing an IncH12 plasmid carrying both the blaVIM-1 carbapenemase and the mcr-9 colistin resistance gene.

Published
2021

45. 'I Feel Worn Out, as if I Neglected Myself'

Author

Barbara C. van Munster, Dirk R Essink, Lucienne A Reichardt, Rosanne van Seben, Bianca M. Buurman, Jos A. Bosch, Science and Society, APH - Global Health, Klinische Psychologie (Psychologie, FMG), Graduate School, AMS - Ageing & Morbidty, APH - Aging & Later Life, APH - Quality of Care, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Geriatrics, Nursing, APH - Mental Health, and Molecular Neuroscience and Ageing Research (MOLAR)

Subjects
Male, Activities of daily living, TRANSITIONAL CARE, LAST YEAR, 030204 cardiovascular system & hematology, Fear of falling, 0302 clinical medicine, Transitional care, Apathy, 030212 general & internal medicine, Prospective cohort study, Acute hospitalization, PREDICTORS, Fatigue, Qualitative Research, FUNCTIONAL DECLINE, Aged, 80 and over, education.field_of_study, Fear, General Medicine, Patient Discharge, Hospitalization, Female, Thematic analysis, medicine.symptom, RESTRICTED ACTIVITY, medicine.medical_specialty, Population, POSTSTROKE FATIGUE, 03 medical and health sciences, Posthospitalization, medicine, Older patients, Humans, Mobility Limitation, Psychiatry, education, Aged, business.industry, Recovery of Function, ADULTS, MYOCARDIAL-INFARCTION, PROSPECTIVE COHORT, Symptoms, GERIATRIC SYNDROMES, Accidental Falls, Geriatrics and Gerontology, business, Gerontology, Qualitative research
Abstract

BackgroundThe transition between hospital and home is a vulnerable period for acutely hospitalized older patients during which they are at increased risk for adverse health outcomes. Yet, studies describing experiences of a geriatric patient population postdischarge from a patient perspective are missing.ObjectiveTo characterize patient experiences with recovering at home after acute hospitalization.Design and MethodsQualitative semi-structured interviews, involving 20 recently discharged patients (age ≥ 70), were conducted. A thematic analysis of the content was performed.ResultsTen categories were identified as recurring topics, which were grouped into 3 major themes. The first theme describes the effect of hospitalization on daily life. Participants described that the problems they encountered were mostly caused by symptoms they experienced since discharge, which were grouped into 2 themes: (a) physical consequences of hospitalization and (b) motivational and psychological problems after hospitalization. Among most frequently presented symptoms were fatigue, apathy, unsteadiness while standing, and fear of falling.ImplicationsImpairment in mobility and instrumental activities of daily living was the dominant experience for interviewed patients. This disability was mainly attributed to four main symptoms: fatigue, apathy, unsteadiness while standing, and fear of falling. We propose a tentative model that summarizes the role of posthospital symptoms in the recovery process and the potential syndromes (frailty, posthospital syndrome, palliative symptoms, and sickness behavior) that could underlie these shared symptoms which may act as a conceptual framework for future research. Our study points at the relevance of symptom experiences in functional recovery postdischarge.

Published
2019

46. Cancer-Related Fatigue and Rehabilitation

Author

Wendy J. Post, Irene Korstjens, Bart van den Borne, Ilse Mesters, Josette E. H. M. Hoekstra-Weebers, Cees P. van der Schans, Wynand J. G. Ros, Anne M. May, Ellen van Weert, Science in Healthy Ageing & healthcaRE (SHARE), Extremities Pain and Disability (EXPAND), Health Psychology Research (HPR), Healthy Ageing, Allied Health Care and Nursing, Health promotion, RS: CAPHRI School for Public Health and Primary Care, and Epidemiologie

Subjects
Male, medicine.medical_specialty, FITNESS, medicine.medical_treatment, Physical Therapy, Sports Therapy and Rehabilitation, DISEASE, law.invention, Physical medicine and rehabilitation, Quality of life, Randomized controlled trial, law, QUALITY-OF-LIFE, Intervention (counseling), Multicenter trial, Neoplasms, Surveys and Questionnaires, medicine, PROGRAM, MANAGEMENT, cancer, Humans, Cancer-related fatigue, Fatigue, METAANALYSIS, Netherlands, SURVIVORS, vermoeidheid, Analysis of Variance, Rehabilitation, Chi-Square Distribution, Cognitive Behavioral Therapy, business.industry, EXERCISE INTERVENTIONS, Middle Aged, EFFICACY, Exercise Therapy, Cognitive behavioral therapy, kanker, Treatment Outcome, Physical therapy, Quality of Life, Patient Compliance, Female, medicine.symptom, business, Chi-squared distribution, RESISTANCE
Abstract

Background Research suggests that cancer rehabilitation reduces fatigue in survivors of cancer. To date, it is unclear what type of rehabilitation is most beneficial. Objective This randomized controlled trial compared the effect on cancer-related fatigue of physical training combined with cognitive behavioral therapy with physical training alone and with no intervention. Design In this multicenter randomized controlled trial, 147 survivors of cancer were randomly assigned to a group that received physical training combined with cognitive-behavioral therapy (PT+CBT group, n=76) or to a group that received physical training alone (PT group, n=71). In addition, a nonintervention control group (WLC group) consisting of 62 survivors of cancer who were on the waiting lists of rehabilitation centers elsewhere was included. Setting The study was conducted at 4 rehabilitation centers in the Netherlands. Patients All patients were survivors of cancer. Intervention Physical training consisting of 2 hours of individual training and group sports took place twice weekly, and cognitive-behavioral therapy took place once weekly for 2 hours. Measurements Fatigue was assessed with the Multidimensional Fatigue Inventory before and immediately after intervention (12 weeks after enrollment). The WLC group completed questionnaires at the same time points. Results Baseline fatigue did not differ significantly among the 3 groups. Over time, levels of fatigue significantly decreased in all domains in all groups, except in mental fatigue in the WLC group. Analyses of variance of postintervention fatigue showed statistically significant group effects on general fatigue, on physical and mental fatigue, and on reduced activation but not on reduced motivation. Compared with the WLC group, the PT group reported significantly greater decline in 4 domains of fatigue, whereas the PT+CBT group reported significantly greater decline in physical fatigue only. No significant differences in decline in fatigue were found between the PT+CBT and PT groups. Conclusions Physical training combined with cognitive-behavioral therapy and physical training alone had significant and beneficial effects on fatigue compared with no intervention. Physical training was equally effective as or more effective than physical training combined with cognitive-behavioral therapy in reducing cancer-related fatigue, suggesting that cognitive-behavioral therapy did not have additional beneficial effects beyond the benefits of physical training.

Published
2010

47. Hypertension self-management trajectory patterns and associated factors among Chinese patients with aortic dissection after surgical repair: A longitudinal study.

Author

Zeng M, Wang R, and Cao X

Abstract

Aims: In patients with aortic dissection (AD) after surgical repair, especially those with hypertension, better management of blood pressure is associated with better health outcomes. The aim of this study is to identify hypertension self-management trajectory patterns and associated factors among Chinese aortic dissection patients after surgical repair to assist in developing tailored behavioural interventions for this population., Methods and Results: 178 patients with aortic dissection who underwent surgical repair were followed for 3 months. Data on hypertension self-management, hypertension knowledge, self-efficacy, and social support were collected before discharge and at 1 and 3 months after discharge. Sociodemographic and clinical data were also collected. A latent class growth model and generalized estimating equations were used to explore hypertension self-management trajectory patterns and factors associated with each pattern. The participants' average age was 57.95 (± 11.27) years. Two hypertension self-management trajectory patterns were identified: 'rapid ascent then suppressed growth' (93.4%) and 'continuously slow ascent' (6.6%). For the 'rapid ascent then suppressed growth' pattern, age, educational background, type of health insurance, family monthly income, self-efficacy, and social support were associated with this pattern (P < 0.05)., Conclusion: Healthcare providers may prioritize hypertension self-management for patients who are younger, have lower educational levels, have resident or employee medical insurance and have a family monthly income between 5001 and 10 000 yuan. Self-efficacy and social support might serve as targets for future intervention to improve hypertension self-management., Registration: ChiCTR2100050542., Competing Interests: Conflict of interest: none., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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49. Drug survival of biologics in patients with psoriasis: real-world evidence for Greece during the period 2016-2020.

Author

Lazaridou E, Kourlaba G, Ravanidis S, Gounelas G, Stefanou G, Tsolakidis A, Mathioudakis K, and Apalla Z

Subjects
Humans, Greece epidemiology, Retrospective Studies, Male, Female, Middle Aged, Adult, Arthritis, Psoriatic drug therapy, Antibodies, Monoclonal, Humanized therapeutic use, Aged, Dermatologic Agents therapeutic use, Treatment Outcome, Psoriasis drug therapy, Psoriasis mortality, Biological Products therapeutic use
Abstract

Background: Drug persistence is a crucial aspect of treatment success in psoriasis., Objectives: To record real-world evidence concerning drug survival of biologic agents used for psoriasis treatment and to detect associated modifying factors in Greece., Methods: This was a retrospective cohort study based on data extracted from the nationwide Greek prescription system. Included patients had psoriasis, with or without concomitant psoriatic arthritis (PsA), and had initiated biologics between 1 January 2016 and 31 December 2020., Results: We included 8819 patients who received 13 359 treatment lines. Among them, 76.8% of patients were biologic naive and 16.5% were diagnosed with concomitant PsA. The overall median drug survival was 34.3 months [95% confidence interval (CI) 32.6-36.5]. Drug persistence at 12, 24, 36 and 48 months of follow-up was 71.9%, 57.7%, 49.0% and 43.7%, respectively. Patients receiving brodalumab had the highest drug survival rate in the first 2 years, while secukinumab had the highest rates beyond this period. Overall, drug survival rates were higher in the first treatment line (median 51.1 months, 95% CI 47.1 to not reached) than in the second line and onwards (median 21.7 months, 95% CI 20.0-23.5). Treatment line, PsA status, age and sex were found to significantly affect drug survival rates., Conclusions: Our findings confirm previous reports regarding the importance of efficient first-line biologics and the vulnerability of patients to coexistent PsA. The use of antibodies against interleukins confers high drug survival rates. These results will assist clinical management of patients with psoriasis in Greece., Competing Interests: Conflicts of interest E.L.: Research grant to Aristotle University, Thessaloniki by LEO Pharma for the present study. Payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events, participation on a data safety monitoring board or advisory board, and support for attending meetings and/or travel from AbbVie, Novartis, Pfizer, UCB, Lilly, Sanofi, Genesis Pharma, Amgen, Janssen, Galderma, Galenica and LEO Pharma. G.K.: Payments from Aristotle University, Thessaloniki for this work. Contract with Pfizer via the University of the Peloponnese for a therapeutic area other than psoriasis. Contracts with UCB, AbbVie, LEO and BMS via a consulting firm. SR: employee of ECONCARE LP, which had contracts with UCB, AbbVie, LEO and BMS. G.G.: employee of ECONCARE LP, which had contracts with UCB, AbbVie, LEO and BMS. G.S.: employee of ECONCARE LP, which had contracts with UCB, AbbVie, LEO and BMS. Payments from Aristotle University, Thessaloniki for this work. Contract with Pfizer via the University of the Peloponnese for a therapeutic area other than psoriasis. Z.A.: Honoraria for lectures and for travel from AbbVie, Sanofi, Pfizer, LEO, Janssen and UCB. A.T. and K.M. declare no conflicts of interest., (© The Author(s) 2024. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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50. Quality of life in patients with acquired dermal macular hyperpigmentation: a systematic review.

Author

Jiang M, Wang E, and Rodrigues M

Subjects
Humans, Melanosis psychology, Quality of Life, Hyperpigmentation psychology, Hyperpigmentation etiology
Abstract

Acquired dermal macular hyperpigmentation (ADMH) encompasses conditions including lichen planus pigmentosus, erythema dyschromicum perstans, ashy dermatosis, Riehl melanosis and pigmented contact dermatitis. This group of cosmetically distressing pigmentary disorders poses a therapeutic challenge, yet to our knowledge, there have been no systematic reviews published that describe their impact on quality of life (QoL). An electronic database search of PubMed, Embase, PsycINFO and Cochrane Library was performed in December 2022 to search for articles published from inception until 15 December 2022. Articles were included if they (i) were a primary clinical publication, (ii) reported QoL in patients with ADMH, and (iii) were available in full text. Overall, the review highlighted a considerable gap in the literature concerning the impact of ADMH on QoL. Seven studies fulfilling the inclusion criteria were included, with a total of 259 patients. All seven studies reported impaired QoL in patients with ADMH. The currently available literature on this topic indicates that ADMH has a significant adverse impact on QoL, likely to a greater degree than melasma, and to a similar or lesser degree than vitiligo. Five of seven studies reported the QoL impairment for patients with ADMH based on the Dermatology Life Quality Index (DLQI); these studies consistently found a mean DLQI score reflective of a moderate effect on patients' QoL. Clinicians must be aware of the significant psychosocial burden associated with ADMH. This impact is often overlooked but should be considered when taking a holistic approach to management., Competing Interests: Conflicts of interest The authors declare no conflicts of interest., (© The Author(s) 2024. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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