37 results on '"Sherrington, C"'
Search Results
2. Considerations across multiple stakeholder groups when implementing fall prevention programs in the acute hospital setting: a qualitative study.
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McLennan C, Sherrington C, Tilden W, Jennings M, Richards B, Hill AM, Fairbrother G, Ling F, Naganathan V, and Haynes A
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- Humans, Male, Female, Interviews as Topic, Middle Aged, Hospitals, Public, Aged, Health Knowledge, Attitudes, Practice, Patient Safety, Risk Factors, Adult, Patient Education as Topic, Accidental Falls prevention & control, Qualitative Research, Stakeholder Participation, Focus Groups, Attitude of Health Personnel
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Background: Falls in hospital remain a common and costly patient safety issue internationally. There is evidence that falls in hospitals can be prevented by multifactorial programs and by education for patients and staff, but these are often not routinely or effectively implemented in practice. Perspectives of multiple key stakeholder groups could inform implementation of fall prevention strategies., Methods: Clinicians of different disciplines, patients and their families were recruited from wards at two acute public hospitals. Semi-structured interviews and focus groups were conducted to gain a broad understanding of participants' perspectives about implementing fall prevention programs. Data were analysed using an inductive thematic approach., Results: Data from 50 participants revealed three key themes across the stakeholder groups shaping implementation of acute hospital fall prevention programs: (i) 'Fall prevention is a priority, but whose?' where participants agreed falls in hospital should be addressed but did not necessarily see themselves as responsible for this; (ii) 'Disempowered stakeholders' where participants expressed feeling frustrated and powerless with fall prevention in acute hospital settings; and (iii) 'Shared responsibility may be a solution' where participants were optimistic about the positive impact of collective action on effectively implementing fall prevention strategies., Conclusion: Key stakeholder groups agree that hospital fall prevention is a priority, however, challenges related to role perception, competing priorities, workforce pressure and disempowerment mean fall prevention may often be neglected in practice. Improving shared responsibility for fall prevention implementation across disciplines, organisational levels and patients, family and staff may help overcome this., (© The Author(s) 2024. Published by Oxford University Press on behalf of the British Geriatrics Society.)
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- 2024
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3. Hospital-Based Health Professionals' Perceptions of Frailty in Older People.
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Manuel K, Crotty M, Kurrle SE, Cameron ID, Lane R, Lockwood K, Block H, Sherrington C, Pond D, Nguyen TA, and Laver K
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- Humans, Male, Female, Aged, Australia, Health Personnel psychology, Geriatric Assessment methods, Health Knowledge, Attitudes, Practice, Middle Aged, Interviews as Topic, Adult, Attitude of Health Personnel, Frailty diagnosis, Frail Elderly psychology, Qualitative Research
- Abstract
Background and Objectives: There is a high prevalence of frailty amongst older patients in hospital settings. Frailty guidelines exist but implementation to date has been challenging. Understanding health professional attitudes, knowledge, and beliefs about frailty is critical in understanding barriers and enablers to guideline implementation, and the aim of this study was to understand these in rehabilitation multidisciplinary teams in hospital settings., Research Design and Methods: Twenty-three semistructured interviews were conducted with health professionals working in multidisciplinary teams on geriatric and rehabilitation wards in Adelaide and Sydney, Australia. Interviews were audio recorded, transcribed, and coded by 2 researchers. A codebook was created and interviews were recoded and applied to the Framework Method of thematic analysis., Results: Three domains were developed: diagnosing frailty, communicating about frailty, and managing frailty. Within these domains, 8 themes were identified: (1) diagnosing frailty has questionable benefits, (2) clinicians don't use frailty screening tools, (3) frailty can be diagnosed on appearance and history, (4) frailty has a stigma, (5) clinicians don't use the word "frail" with patients, (6) frailty isn't always reversible, (7) there is a lack of continuity of care after acute admission, and (8) the community setting lacks resources., Discussion and Implications: Implementation of frailty guidelines will remain challenging while staff avoid using the term "frail," don't perceive benefit of using screening tools, and focus on the individual aspects of frailty rather than the syndrome holistically. Clinical champions and education about frailty identification, reversibility, management, and communication techniques may improve the implementation of frailty guidelines in hospitals., (© The Author(s) 2024. Published by Oxford University Press on behalf of The Gerontological Society of America.)
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- 2024
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4. Use of behavior change techniques in physical activity programs and services for older adults: findings from a rapid review.
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Gilchrist H, Oliveira JS, Kwok WS, Sherrington C, Pinheiro MB, Bauman A, Tiedemann A, and Hassett L
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- Aged, Humans, Quality of Life, Randomized Controlled Trials as Topic, Behavior Therapy methods, Exercise
- Abstract
Background: Understanding behavior change techniques (BCTs) used in randomized controlled trials (RCTs) of physical activity programs/services for older adults can help us to guide their implementation in real-world settings., Purpose: This study aims to: (a) identify the number and type of BCTs used in physical activity programs/services for older adults evaluated in large, good quality RCTs and (b) explore the impact of different BCTs on different outcome domains., Methods: This is a secondary data analysis of a WHO-commissioned rapid review of physical activity programs/services for older adults. Fifty-six trials testing 70 interventions were coded for the type and number of BCTs present using a published BCT taxonomy. The proportion of positive effects found from physical activity interventions using the most common BCTs was calculated for the outcomes of physical activity, intrinsic capacity, functional ability, social domain, cognitive and emotional functioning, and well-being and quality of life., Results: Thirty-nine of the 93 possible BCTs were identified in the included trials and 529 BCTs in total (mean 7.6, range 2-17). The most common BCTs were "action planning" (68/70 interventions), "instructions on how to perform a behavior" (60/70), "graded tasks" (53/70), "demonstration of behavior" (44/70), and "behavioral practice/rehearsal" (43/70). Interventions that used any of the most common BCTs showed overwhelmingly positive impacts on physical activity and social domain outcomes., Conclusion: Consideration of which BCTs are included in interventions and their impact on outcomes can improve the effectiveness and implementation of future interventions. To enable this, providers can design, implement, and evaluate interventions using a BCT taxonomy., (© The Author(s) 2024. Published by Oxford University Press on behalf of the Society of Behavioral Medicine.)
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- 2024
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5. Exercise for falls prevention in aged care: systematic review and trial endpoint meta-analyses.
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Dyer SM, Suen J, Kwok WS, Dawson R, McLennan C, Cameron ID, Hill KD, and Sherrington C
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- Aged, Humans, Exercise, Accidental Falls prevention & control
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Background: There is strong evidence that exercise reduces falls in older people living in the community, but its effectiveness in residential aged care is less clear. This systematic review examines the effectiveness of exercise for falls prevention in residential aged care, meta-analysing outcomes measured immediately after exercise or after post-intervention follow-up., Methods: Systematic review and meta-analysis, including randomised controlled trials from a Cochrane review and additional trials, published to December 2022. Trials of exercise as a single intervention compared to usual care, reporting data suitable for meta-analysis of rate or risk of falls, were included. Meta-analyses were conducted according to Cochrane Collaboration methods and quality of evidence rated using the Grading of Recommendations Assessment, Development and Evaluation approach., Results: 12 trials from the Cochrane review plus 7 new trials were included. At the end of the intervention period, exercise probably reduces the number of falls (13 trials, rate ratio [RaR] = 0.68, 95% confidence interval [CI] = 0.49-0.95), but after post-intervention follow-up exercise had little or no effect (8 trials, RaR = 1.01, 95% CI = 0.80-1.28). The effect on the risk of falling was similar (end of intervention risk ratio (RR) = 0.84, 95% CI = 0.72-0.98, 12 trials; post-intervention follow-up RR = 1.05, 95% CI = 0.92-1.20, 8 trials). There were no significant subgroup differences according to cognitive impairment., Conclusions: Exercise is recommended as a fall prevention strategy for older people living in aged care who are willing and able to participate (moderate certainty evidence), but exercise has little or no lasting effect on falls after the end of a programme (high certainty evidence)., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2023
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6. Critical features of multifactorial interventions for effective falls reduction in residential aged care: a systematic review, intervention component analysis and qualitative comparative analysis.
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Suen J, Kneale D, Sutcliffe K, Kwok W, Cameron ID, Crotty M, Sherrington C, and Dyer S
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- Aged, Humans, Homes for the Aged, Randomized Controlled Trials as Topic, Accidental Falls prevention & control
- Abstract
Background: Multifactorial fall prevention trials providing interventions based on individual risk factors have variable success in aged care facilities. To determine configurations of trial features that reduce falls, intervention component analysis (ICA) and qualitative comparative analysis (QCA) were undertaken., Methods: Randomised controlled trials (RCTs) from a Cochrane Collaboration review (Cameron, 2018) with meta-analysis data, plus trials identified in a systematic search update to December 2021 were included. Meta-analyses were updated. A theory developed through ICA of English publications of trialist's perspectives was assessed through QCA and a subgroup meta-analysis., Results: Pooled effectiveness of multifactorial interventions indicated a falls rate ratio of 0.85 (95% confidence interval, CI, 0.65-1.10; I2 = 85%; 11 trials). All tested interventions targeted both environmental and personal risk factors by including assessment of environmental hazards, a medical or medication review and exercise intervention. ICA emphasised the importance of co-design involving facility staff and managers and tailored intervention delivery to resident's intrinsic factors for successful outcomes. QCA of facility engagement plus tailored delivery was consistent with greater reduction in falls, supported by high consistency (0.91) and coverage (0.85). An associated subgroup meta-analysis demonstrated strong falls reduction without heterogeneity (rate ratio 0.61, 95%CI 0.54-0.69, I2 = 0%; 7 trials)., Conclusion: Multifactorial falls prevention interventions should engage aged care staff and managers to implement strategies which include tailored intervention delivery according to each resident's intrinsic factors. Such approaches are consistently associated with a successful reduction in falls, as demonstrated by QCA and subgroup meta-analyses. Co-design approaches may also enhance intervention success., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society.)
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- 2023
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7. Perioperative interventions to improve early mobilisation and physical function after hip fracture: a systematic review and meta-analysis.
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Sarkies MN, Testa L, Carrigan A, Roberts N, Gray R, Sherrington C, Mitchell R, Close JCT, McDougall C, and Sheehan K
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- Aged, Aged, 80 and over, Humans, Bicycling, Dietary Supplements, Pain Management, Early Ambulation, Hip Fractures rehabilitation, Hip Fractures surgery, Perioperative Care
- Abstract
Background: Perioperative interventions could enhance early mobilisation and physical function after hip fracture surgery., Objective: Determine the effectiveness of perioperative interventions on early mobilisation and physical function after hip fracture., Methods: Ovid MEDLINE, CINAHL, Embase, Scopus and Web of Science were searched from January 2000 to March 2022. English language experimental and quasi-experimental studies were included if patients were hospitalised for a fractured proximal femur with a mean age 65 years or older and reported measures of early mobilisation and physical function during the acute hospital admission. Data were pooled using a random effect meta-analysis., Results: Twenty-eight studies were included from 1,327 citations. Studies were conducted in 26 countries on 8,192 participants with a mean age of 80 years. Pathways and models of care may provide a small increase in early mobilisation (standardised mean difference [SMD]: 0.20, 95% confidence interval [CI]: 0.01-0.39, I2 = 73%) and physical function (SMD: 0.07, 95% CI 0.00 to 0.15, I2 = 0%) and transcutaneous electrical nerve stimulation analgesia may provide a moderate improvement in function (SMD: 0.65, 95% CI: 0.24-1.05, I2 = 96%). The benefit of pre-operative mobilisation, multidisciplinary rehabilitation, recumbent cycling and clinical supervision on mobilisation and function remains uncertain. Evidence of no effect on mobilisation or function was identified for pre-emptive analgesia, intraoperative periarticular injections, continuous postoperative epidural infusion analgesia, occupational therapy training or nutritional supplements., Conclusions: Perioperative interventions may improve early mobilisation and physical function after hip fracture surgery. Future studies are needed to model the causal mechanisms of perioperative interventions on mobilisation and function after hip fracture., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2023
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8. Physical activity and injurious falls in older Australian women: adjusted associations and modification by physical function limitation and frailty in the Australian Longitudinal Study on Women's Health.
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Kwok WS, Dolja-Gore X, Khalatbari-Soltani S, Byles J, Oliveira JS, Pinheiro MB, Naganathan V, Tiedemann A, and Sherrington C
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- Female, Humans, Aged, Cross-Sectional Studies, Longitudinal Studies, Prospective Studies, Australia epidemiology, Exercise, Women's Health, Accidental Falls prevention & control, Frailty diagnosis, Frailty epidemiology
- Abstract
Objectives: To investigate associations between leisure-time physical activity (LPA) and injurious falls in older women and explore modification of associations by physical function and frailty., Methods: Women born during 1946-51 from the Australian Longitudinal Study on Women's Health, injurious falls (self-reported fall with injury and/or medical attention) and self-reported weekly LPA (duration and type). We undertook cross-sectional and prospective analyses using data from 2016 [n = 8,171, mean (SD) age 68 (1)] and 2019 surveys (n = 7,057). Associations were quantified using directed acyclic graph-informed logistic regression and effect modification examined using product terms., Results: Participation in LPA as recommended by World Health Organization (150-300 min/week) was associated with lower odds of injurious falls in cross-sectional (adjusted Odds Ratio (OR) 0.74, 95% CI 0.61-0.90) and prospective analyses (OR 0.75, 95% CI 0.60-0.94). Compared with those who reported no LPA, cross-sectionally, odds of injurious falls were lower in those who reported brisk walking (OR 0.77, 95% CI 0.67-0.89) and vigorous LPA (OR 0.86, 95% CI 0.75-1.00). No significant association was found between different types of LPA and injurious falls prospectively. Only cross-sectionally, physical function limitation and frailty modified the association between LPA and injurious falls, with tendencies for more injurious falls with more activity in those with physical limitation or frailty, and fewer injurious falls with more activity among those without physical function limitation or frailty., Conclusion: Participation in recommended levels of LPA was associated with lower odds of injurious falls. Caution is required when promoting general physical activity among people with physical limitation or frailty., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2023
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9. Cost-effectiveness of physical activity programs and services for older adults: a scoping review.
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Pinheiro MB, Howard K, Oliveira JS, Kwok WS, Tiedemann A, Wang B, Taylor J, Bauman A, and Sherrington C
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- Humans, Aged, Cost-Benefit Analysis, Systematic Reviews as Topic, Exercise
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Background: Evidence supporting physical activity for older adults is strongly positive. Implementation and scale-up of these interventions need to consider the value for money. This scoping review aimed to assess the volume of (i) systematic review evidence regarding economic evaluations of physical activity interventions, and (ii) of cost utility analysis (CUA) studies (trial- or model-based) of physical activity interventions for older people., Methods: We searched five databases (January 2010 to February 2022) for systematic reviews of economic evaluations, and two databases (1976 to February 2022) for CUA studies of physical activity interventions for any population of people aged 60+ years., Results: We found 12 potential reviews, two of which were eligible for inclusion. The remaining 10 reviews included eligible individual studies that were included in this review. All individual studies from the 12 reviews (n = 37) investigated the cost-effectiveness of structured exercise and most showed the intervention was more costly but more effective than no intervention. We identified 27 CUA studies: two investigated a physical activity promotion program and the remainder investigated structured exercise. Most interventions (86%) were more costly but more effective, and the remaining were cost-saving compared to no intervention., Conclusions: There is a scarcity of reviews investigating the value for money of physical activity interventions for older adults. Most studies investigated structured exercise. Physical activity interventions were generally more effective than no intervention but more costly. As such an intervention could be cost-effective and therefore worthy of wider implementation, but there is a need for more frequent economic evaluation in this field., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2023
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10. Fall-related health service use in Stepping On programme participants and matched controls: a non-randomised observational trial within the 45 and Up Study.
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Paul SS, Khalatbari-Soltani S, Dolja-Gore X, Clemson L, Lord SR, Harvey L, Tiedemann A, Close JCT, and Sherrington C
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- Humans, Aged, Australia, New South Wales, Patient Acceptance of Health Care
- Abstract
Background: Falls and fall-related health service use among older adults continue to increase. The New South Wales Health Department, Australia, is delivering the Stepping On fall prevention programme at scale. We compared fall-related health service use in Stepping On participants and matched controls., Methods: A non-randomised observational trial was undertaken using 45 and Up Study data. 45 and Up Study participants who did and did not participate in Stepping On were extracted in a 1:4 ratio. Rates of fall-related health service use from linked routinely collected data were compared between participants and controls over time using multilevel Poisson regression models with adjustment for the minimally sufficient set of confounders identified from a directed acyclic graph., Results: Data from 1,452 Stepping On participants and 5,799 controls were analysed. Health service use increased over time and was greater in Stepping On participants (rate ratios (RRs) 1.47-1.82) with a spike in use in the 6 months prior to programme participation. Significant interactions indicated differential patterns of health service use in participants and controls: stratified analyses revealed less fall-related health service use in participants post-programme compared to pre-programme (RRs 0.32-0.48), but no change in controls' health service use (RRs 1.00-1.25). Gender was identified to be a significant effect modifier for health service use (P < 0.05 for interaction)., Discussion: Stepping On appeared to mitigate participants' rising fall-related health service use. Best practice methods were used to maximise this study's validity, but cautious interpretation of results is required given its non-randomised nature., (© The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2022
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11. World guidelines for falls prevention and management for older adults: a global initiative.
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Montero-Odasso M, van der Velde N, Martin FC, Petrovic M, Tan MP, Ryg J, Aguilar-Navarro S, Alexander NB, Becker C, Blain H, Bourke R, Cameron ID, Camicioli R, Clemson L, Close J, Delbaere K, Duan L, Duque G, Dyer SM, Freiberger E, Ganz DA, Gómez F, Hausdorff JM, Hogan DB, Hunter SMW, Jauregui JR, Kamkar N, Kenny RA, Lamb SE, Latham NK, Lipsitz LA, Liu-Ambrose T, Logan P, Lord SR, Mallet L, Marsh D, Milisen K, Moctezuma-Gallegos R, Morris ME, Nieuwboer A, Perracini MR, Pieruccini-Faria F, Pighills A, Said C, Sejdic E, Sherrington C, Skelton DA, Dsouza S, Speechley M, Stark S, Todd C, Troen BR, van der Cammen T, Verghese J, Vlaeyen E, Watt JA, and Masud T
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- Aged, Caregivers, Humans, Risk Assessment, Independent Living, Quality of Life
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Background: falls and fall-related injuries are common in older adults, have negative effects on functional independence and quality of life and are associated with increased morbidity, mortality and health related costs. Current guidelines are inconsistent, with no up-to-date, globally applicable ones present., Objectives: to create a set of evidence- and expert consensus-based falls prevention and management recommendations applicable to older adults for use by healthcare and other professionals that consider: (i) a person-centred approach that includes the perspectives of older adults with lived experience, caregivers and other stakeholders; (ii) gaps in previous guidelines; (iii) recent developments in e-health and (iv) implementation across locations with limited access to resources such as low- and middle-income countries., Methods: a steering committee and a worldwide multidisciplinary group of experts and stakeholders, including older adults, were assembled. Geriatrics and gerontological societies were represented. Using a modified Delphi process, recommendations from 11 topic-specific working groups (WGs), 10 ad-hoc WGs and a WG dealing with the perspectives of older adults were reviewed and refined. The final recommendations were determined by voting., Recommendations: all older adults should be advised on falls prevention and physical activity. Opportunistic case finding for falls risk is recommended for community-dwelling older adults. Those considered at high risk should be offered a comprehensive multifactorial falls risk assessment with a view to co-design and implement personalised multidomain interventions. Other recommendations cover details of assessment and intervention components and combinations, and recommendations for specific settings and populations., Conclusions: the core set of recommendations provided will require flexible implementation strategies that consider both local context and resources., (© The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2022
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12. Acceptability and feasibility of an online physical activity program for women over 50: a pilot trial.
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Wallbank G, Sherrington C, Hassett L, Kwasnicka D, Chau JY, Phongsavan P, Grunseit A, Martin F, Canning CG, Baird M, Shepherd R, and Tiedemann A
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- Electronic Mail, Feasibility Studies, Female, Humans, Middle Aged, Pilot Projects, Exercise, Sedentary Behavior
- Abstract
Regular physical activity benefits health across the lifespan. Women in middle-age often juggle carer and work responsibilities, are often inactive, and may benefit from tailored support to increase physical activity. Establish the acceptability, feasibility, and impact on physical activity of a scalable program for women 50+ years. This pilot trial randomized participants to immediate program access, or to a wait-list control. [Active Women over 50 Online] program included: (1) study-specific website, (2) 8 emails or 24 SMS motivation-based messages, (3) one telephone health-coaching session. Outcomes, at 3 months, were acceptability (recommend study participation, intervention uptake), feasibility (recruitment, reach, completion), intervention impact (physical activity), intervention impressions. At baseline, 62 participants of mean (SD) age 59 (±7) years took 7459 (±2424) steps/day and most (92%) reported ≥2 medical conditions. At 3 months, acceptability and impact data were available for 52 (84%) and 57 (92%) participants, respectively. Study participation was recommended by 83% of participants. Participants mostly agreed to receive health coaching (81%) and messages (87%: email = 56%, SMS = 44%), opened 82% of emails and accessed the website 4.8 times on average. Respondents reported the intervention supported their physical activity. Intervention participants were more likely to increase steps from baseline by 2000+/day (OR: 6.31, 95% CI: 1.22 to 32.70, p = .028) than controls, and trended toward more light-intensity (p = .075) and moderate-vigorous intensity physical activity (p = .11). The [Active Women over 50 Online] program demonstrated acceptability and feasibility among the target population, and effectiveness in some domains in the short term. Results warrant further testing in a full-scale RCT., (© Society of Behavioral Medicine 2022. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2022
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13. New horizons in falls prevention and management for older adults: a global initiative.
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Montero-Odasso M, van der Velde N, Alexander NB, Becker C, Blain H, Camicioli R, Close J, Duan L, Duque G, Ganz DA, Gómez F, Hausdorff JM, Hogan DB, Jauregui JR, Kenny RA, Lipsitz LA, Logan PA, Lord SR, Mallet L, Marsh DR, Martin FC, Milisen K, Nieuwboer A, Petrovic M, Ryg J, Sejdic E, Sherrington C, Skelton DA, Speechley M, Tan MP, Todd C, van der Cammen T, Verghese J, Kamkar N, Sarquis-Adamson Y, and Masud T
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- Aged, Consensus, Humans, Caregivers, Quality of Life
- Abstract
Background: falls and fall-related injuries are common in older adults, have negative effects both on quality of life and functional independence and are associated with increased morbidity, mortality and health care costs. Current clinical approaches and advice from falls guidelines vary substantially between countries and settings, warranting a standardised approach. At the first World Congress on Falls and Postural Instability in Kuala Lumpur, Malaysia, in December 2019, a worldwide task force of experts in falls in older adults, committed to achieving a global consensus on updating clinical practice guidelines for falls prevention and management by incorporating current and emerging evidence in falls research. Moreover, the importance of taking a person-centred approach and including perspectives from patients, caregivers and other stakeholders was recognised as important components of this endeavour. Finally, the need to specifically include recent developments in e-health was acknowledged, as well as the importance of addressing differences between settings and including developing countries., Methods: a steering committee was assembled and 10 working Groups were created to provide preliminary evidence-based recommendations. A cross-cutting theme on patient's perspective was also created. In addition, a worldwide multidisciplinary group of experts and stakeholders, to review the proposed recommendations and to participate in a Delphi process to achieve consensus for the final recommendations, was brought together., Conclusion: in this New Horizons article, the global challenges in falls prevention are depicted, the goals of the worldwide task force are summarised and the conceptual framework for development of a global falls prevention and management guideline is presented., (© The Author(s) 2021. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2021
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14. Interventions Promoting Physical Activity Among Older Adults: A Systematic Review and Meta-Analysis.
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Grande GD, Oliveira CB, Morelhão PK, Sherrington C, Tiedemann A, Pinto RZ, and Franco MR
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- Aged, Bias, Humans, Middle Aged, Self Report, Exercise, Independent Living
- Abstract
Background and Objectives: Frequent participation in physical activity (PA) has benefits across the lifespan but is particularly important for older adults. PA levels are either measured by objective or self-reported survey methods. Objective PA measurement is used to increase accuracy. This systematic review investigated the effect of physical activity-based interventions on objectively measured PA levels among community-dwelling adults aged 60 years and older., Research Design and Methods: Literature searches were conducted in five electronic databases and four clinical trial registries. Randomized controlled trials investigating the effect of physical activity-based interventions on objectively measured PA levels (e.g., accelerometers or pedometers) in community-dwelling adults aged 60 years and older compared with no/minimal intervention were considered eligible. Data were pooled using the most conservative estimates reported from each study using the standardized mean difference (SMD). Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to evaluate the overall quality of the evidence., Results: Fourteen published trials and 3 ongoing trials were identified. There were significant effects favoring physical activity-based interventions compared with minimal intervention at short-term (less than or equal to 3 months) (SMD: 0.30, 95% CI: 0.17 to 0.43) and intermediate-term (more than 3 months and less than 12 months; SMD: 0.27, 95% CI: 0.06 to 0.49) follow-ups. The quality of evidence was moderate according to GRADE (downgraded for risk of bias)., Discussion and Implications: Our findings suggest that physical activity-based interventions may increase objectively measured PA levels in community-dwelling older adults. Further studies are still needed to identify the optimal dose, intensity, and mode of delivery of physical activity-based interventions., (© The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2020
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15. Effect of Senior Dance (DanSE) on Fall Risk Factors in Older Adults: A Randomized Controlled Trial.
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Franco MR, Sherrington C, Tiedemann A, Pereira LS, Perracini MR, Faria CSG, Negrão-Filho RF, Pinto RZ, and Pastre CM
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- Aged, Brazil, Case-Control Studies, Cognition, Confidence Intervals, Dance Therapy, Female, Humans, Independent Living, Male, Movement, Outcome Assessment, Health Care, Patient Selection, Sample Size, Single-Blind Method, Time Factors, Accidental Falls prevention & control, Dancing physiology, Postural Balance
- Abstract
Background: Older people's participation in structured exercise programs to improve balance and mobility is low. Senior Dance is an alternative option, as it may provide a safe and fun way of targeting balance., Objective: The aim was to investigate the effect of Senior Dance on balance, mobility, and cognitive function compared with a control intervention., Design: The study was a randomized controlled trial., Setting/patients: Eighty-two community-dwelling older people aged 60 years or over and cognitively intact were recruited in Brazil., Intervention: Participants were randomly allocated to 2 groups: Dance plus education (intervention group) and education alone (control group). The Senior Dance program consisted of 12 weeks of twice-weekly group-based dance classes. Participants in both groups attended a single 1-hour educational session on prevention of falls., Measurements: The primary outcome was single-leg stance with eyes closed. Secondary outcomes were timed sit-to-stand test, standing balance test, timed 4-m walk, and cognitive function tests, for example, Trail Making Test and Montreal Cognitive Assessment., Results: Of the 82 participants randomized, 71 (87%) completed the 12-week follow-up. Single-leg stance with eyes closed (primary outcome) improved in the Senior Dance group (mean difference [MD] = 2.3 seconds, 95% confidence interval [CI] = 1.1 to 3.6) compared with the control group at follow-up. Senior Dance group performed better in the standing balance tests (MD = 3.7 seconds, 95% CI = 0.6 to 6.8) and were faster in the sit-to-stand test (MD = - 3.1 seconds, 95% CI = -4.8 to -1.4) and 4-m walk test (MD = -0.6 seconds, 95% CI = -1.0 to -0.1). There were no significant between-group differences for cognitive function tests., Limitations: Participants and therapists were not blinded., Conclusion: Senior Dance was effective in improving balance and mobility but not cognitive function in community-dwelling older people., (© 2020 American Physical Therapy Association.)
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- 2020
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16. The uptake of the hip fracture core outcome set: analysis of 20 years of hip fracture trials.
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Smith TO, Collier T, Sheehan KJ, and Sherrington C
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- Activities of Daily Living, Arthralgia epidemiology, Arthralgia etiology, Clinical Trials as Topic methods, Clinical Trials as Topic statistics & numerical data, Hip Fractures mortality, Hip Fractures surgery, Humans, Mobility Limitation, Quality of Life, Registries, Treatment Outcome, Hip Fractures therapy, Outcome Assessment, Health Care statistics & numerical data
- Abstract
Background: clinical trials test the effectiveness or efficacy of treatments. It is important that researchers evaluate interventions with the most meaningful outcome measures. The 2014 hip fracture core outcome set recommended that mortality, mobility, pain, activities of daily living and health-related quality of life (HRQOL) should be assessed in all trials of patient with hip fracture. The purpose of this analysis was to determine the uptake of these recommendation., Methods: all trials registered from 1997 to 2018 recruiting participants following hip fracture were identified from the ClinicalTrials.gov trials registry. The frequency of each core domain adopted annually were assessed., Results: 311 trials were identified and analysed. On analysing trial registries for years which presented a minimum of 10 registrations, full core outcome set adoption ranged from 0% (2017; 2018) to 24% (2009). Mortality and mobility were the most consistently reported domains (mortality: 27% (2017) to 56% (2011); mobility: 36% (2015) to 60% (2004)). In contrast, pain and HRQOL were least reported (pain: 14% (2017) to 61% (2015); HRQOL: 10% (2010) to 11% (2008)). There was no clear change in core outcome domain set adoption following the publication of Hayward et al.'s (2014) core outcome set., Conclusions: there has been limited adoption of the hip fracture core outcome set from its publication in 2014. Further consideration to improve implementation is required to improved uptake., (© The Author(s) 2019. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2019
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17. Validity of Different Activity Monitors to Count Steps in an Inpatient Rehabilitation Setting.
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Treacy D, Hassett L, Schurr K, Chagpar S, Paul SS, and Sherrington C
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- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Inpatients, Monitoring, Ambulatory instrumentation, Rehabilitation Centers, Walking physiology
- Abstract
Background: Commonly used activity monitors have been shown to be accurate in counting steps in active people; however, further validation is needed in slower walking populations., Objectives: To determine the validity of activity monitors for measuring step counts in rehabilitation inpatients compared with visually observed step counts. To explore the influence of gait parameters, activity monitor position, and use of walkers on activity monitor accuracy., Methods: One hundred and sixty-six inpatients admitted to a rehabilitation unit with an average walking speed of 0.4 m/s (SD 0.2) wore 16 activity monitors (7 different devices in different positions) simultaneously during 6-minute and 6-m walks. The number of steps taken during the tests was also counted by a physical therapist. Gait parameters were assessed using the GAITRite system. To analyze the influence of different gait parameters, the percentage accuracy for each monitor was graphed against various gait parameters for each activity monitor., Results: The StepWatch, Fitbit One worn on the ankle and the ActivPAL showed excellent agreement with observed step count (ICC 2,1 0.98; 0.92; 0.78 respectively). Other devices (Fitbit Charge, Fitbit One worn on hip, G-Sensor, Garmin Vivofit, Actigraph) showed poor agreement with the observed step count (ICC 2,1 0.12-0.40). Percentage agreement with observed step count was highest for the StepWatch (mean 98%). The StepWatch and the Fitbit One worn on the ankle maintained accuracy in individuals who walked more slowly and with shorter strides but other devices were less accurate in these individuals., Limitations: There were small numbers of participants for some gait parameters., Conclusions: The StepWatch showed the highest accuracy and closest agreement with observed step count. This device can be confidently used by researchers for accurate measurement of step counts in inpatient rehabilitation in individuals who walk slowly. If immediate feedback is desired, the Fitbit One when worn on the ankle would be the best choice for this population., (© 2017 American Physical Therapy Association)
- Published
- 2017
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18. Smallest worthwhile effect of exercise programs to prevent falls among older people: estimates from benefit-harm trade-off and discrete choice methods.
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Franco MR, Howard K, Sherrington C, Rose J, Ferreira PH, and Ferreira ML
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- Accidental Falls economics, Aged, Aged, 80 and over, Cost-Benefit Analysis, Exercise Therapy adverse effects, Exercise Therapy economics, Female, Health Care Costs, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Patient Participation, Risk Assessment, Risk Factors, Surveys and Questionnaires, Treatment Outcome, Accidental Falls prevention & control, Choice Behavior, Decision Support Techniques, Exercise Therapy methods, Process Assessment, Health Care economics
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Background: the smallest worthwhile effect (SWE) of an intervention is the smallest treatment effect that justifies the costs, risks and inconveniences associated with that health intervention., Objective: to estimate the SWE of exercise programs designed to prevent falls among older people and to compare estimates derived by two methodological approaches., Study Design and Setting: discrete choice experiment (n = 220) and benefit-harm trade-off (subsample n = 66) methods were used., Participants: community-dwelling older people who reported a past fall or a mobility limitation answered online or face-to-face questionnaires., Results: a substantial proportion of participants (82% in the discrete choice experiment and 50% in the benefit-harm trade-off study) did not consider that participation in the proposed exercise programs would be worthwhile, even if it reduced their risk of falling to 0%. Among remaining participants, the average SWE of participation in an exercise program was an absolute reduction in the risk of falling of 35% (standard deviation [SD] = 13) in the discrete choice experiment and 16% (SD = 11) in the benefit-harm trade-off study., Conclusions: many participants did not consider the hypothetical falls' risk reduction of the proposed exercise programs to be worth the associated costs and inconveniences. Greater community awareness of the fall prevention effects of exercise for older people is required., (© The Author 2016. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
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- 2016
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19. Yoga-based exercise improves balance and mobility in people aged 60 and over: a systematic review and meta-analysis.
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Youkhana S, Dean CM, Wolff M, Sherrington C, and Tiedemann A
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- Age Factors, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Recovery of Function, Risk Factors, Sensation Disorders diagnosis, Sensation Disorders physiopathology, Treatment Outcome, Accidental Falls prevention & control, Aging, Mobility Limitation, Postural Balance, Sensation Disorders therapy, Yoga
- Abstract
Objective: one-third of community-dwelling older adults fall annually. Exercise that challenges balance is proven to prevent falls. We conducted a systematic review with meta-analysis to determine the impact of yoga-based exercise on balance and physical mobility in people aged 60+ years., Methods: searches for relevant trials were conducted on the following electronic databases: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, CINAHL, Allied and Complementary Medicine Database and the Physiotherapy Evidence Database (PEDro) from inception to February 2015. Trials were included if they evaluated the effect of physical yoga (excluding meditation and breathing exercises alone) on balance in people aged 60+ years. We extracted data on balance and the secondary outcome of physical mobility. Standardised mean differences and 95% confidence intervals (CI) were calculated using random-effects models. Methodological quality of trials was assessed using the 10-point Physiotherapy Evidence Database (PEDro) Scale., Results: six trials of relatively high methodological quality, totalling 307 participants, were identified and had data that could be included in a meta-analysis. Overall, yoga interventions had a small effect on balance performance (Hedges' g = 0.40, 95% CI 0.15-0.65, 6 trials) and a medium effect on physical mobility (Hedges' g = 0.50, 95% CI 0.06-0.95, 3 trials)., Conclusion: yoga interventions resulted in small improvements in balance and medium improvements in physical mobility in people aged 60+ years. Further research is required to determine whether yoga-related improvements in balance and mobility translate to prevention of falls in older people. PROSPERO Registration number CRD42015015872., (© The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
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- 2016
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20. Additional standing balance circuit classes during inpatient rehabilitation improved balance outcomes: an assessor-blinded randomised controlled trial.
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Treacy D, Schurr K, Lloyd B, and Sherrington C
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- Accidental Falls statistics & numerical data, Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Male, Middle Aged, Motor Activity physiology, Retrospective Studies, Single-Blind Method, Time Factors, Treatment Outcome, Accidental Falls prevention & control, Exercise physiology, Exercise Therapy methods, Inpatients, Postural Balance physiology, Rehabilitation Centers
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Objective: to evaluate the impact on balance (postural control) of six 1-h circuit classes that targeted balance in addition to usual therapy for rehabilitation inpatients., Design: a randomised controlled trial with 2-week and 3-month follow-up., Participants: one hundred and sixty-two general rehabilitation inpatients, Bankstown-Lidcombe Hospital, Australia., Intervention: intervention group participants received six 1-h circuit classes over a 2-week period in addition to usual therapy. Control group participants received usual therapy., Results: standing balance performance (primary outcome) was better in the intervention group than in the control group at 2 weeks (between-group difference after adjusting for baseline values 3.3 s; 95% confidence interval (CI) 0.84 to 5.7, P = 0.009), but the between-group difference was not statistically significant at 3 months (3.4 s; 95% CI -0.56 to 7.38, P = 0.092). Intervention group outcomes were significantly better than the control groups for mobility performance (Short Physical Performance Battery) at 2 weeks (1.19, 95% CI 0.52 to 1.87, P <0.01) and 3 months (1.00, 95% CI 0.00 to 2.00, P < 0.049) and self-reported functioning (AM-PAC) at 2 weeks (5.39, 95% CI 1.20 to 9.57, P = 0.012). The intervention group had a 4.1-day shorter rehabilitation unit stay (95% CI -8.3 to 0.16, P = 0.059) and a lower risk of readmission in the 3 months after randomisation (incidence rate ratio 0.70, 95% CI 0.42 to 1.18, P = 0.184), but these differences were not statistically significant., Conclusion: two weeks of standing balance circuit classes in addition to usual therapy improved balance in general rehabilitation inpatients at 2 weeks., (© The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
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- 2015
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21. The impact of a home-based walking programme on falls in older people: the Easy Steps randomised controlled trial.
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Voukelatos A, Merom D, Sherrington C, Rissel C, Cumming RG, and Lord SR
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- Accidental Falls prevention & control, Aged, Aged, 80 and over, Exercise Therapy methods, Female, Humans, Male, Quality of Life, Accidental Falls statistics & numerical data, Walking
- Abstract
Background: walking is the most popular form of exercise in older people but the impact of walking on falls is unclear. This study investigated the impact of a 48-week walking programme on falls in older people., Methods: three hundred and eighty-six physically inactive people aged 65+ years living in the community were randomised into an intervention or control group. The intervention group received a self-paced, 48-week walking programme that involved three mailed printed manuals and telephone coaching. Coinciding with the walking programme manual control group participants received health information unrelated to falls. Monthly falls calendars were used to monitor falls (primary outcome) over 48 weeks. Secondary outcomes were self-reported quality of life, falls efficacy, exercise and walking levels. Mobility, leg strength and choice stepping reaction time were measured in a sub-sample (n = 178) of participants., Results: there was no difference in fall rates between the intervention and control groups in the follow-up period (IRR = 0.88, 95% CI: 0.60-1.29). By the end of the study, intervention group participants spent significantly more time exercising in general, and specifically walking for exercise (median 1.69 versus 0.75 h/week, P < 0.001)., Conclusion: our finding that a walking programme is ineffective in preventing falls supports previous research and questions the suitability of recommending walking as a fall prevention strategy for older people. Walking, however, increases physical activity levels in previously inactive older people., (© The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
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- 2015
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22. Economic modelling of a public health programme for fall prevention.
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Farag I, Howard K, Ferreira ML, and Sherrington C
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- Accidental Falls economics, Aged, Cost-Benefit Analysis, Health Care Costs statistics & numerical data, Health Services for the Aged economics, Humans, Markov Chains, Program Evaluation, Public Health methods, Quality-Adjusted Life Years, Residential Facilities economics, Accidental Falls prevention & control, Models, Economic, Public Health economics
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Background: despite evidence on what works in falls prevention, falls in older people remain an important public health problem., Aims: the purpose of this study was to model the impact and cost-effectiveness of a public health falls prevention programme, from the perspective of the health funder., Methods: a decision analytic Markov model compared the health benefits in quality-adjusted life years (QALYs) and costs of treatment and residential aged care with and without a population heath falls prevention programme. Different intervention costs, uptake levels and programme effectiveness were modelled in sensitivity analyses. Uncertainty was explored using univariate and probabilistic sensitivity analysis., Results: widespread rollout of a public health fall prevention programme could result in an incremental cost-effectiveness ratio (ICER) of $A28,931 per QALY gained, assuming a programme cost of $700 per person and at a fall prevention risk ratio of 0.75. This ICER would be considered cost-effective at a threshold value of $A50,000 per QALY gained. Sensitivity analyses for programme cost and effectiveness indicated that the public health programme produced greater health outcomes and was less costly than no programme when programme costs were $A500 or lower and risk ratio for falls was 0.70 or lower. At a cost of $A2,500, the public health falls prevention programme ceases to be a cost-effective option., Conclusion: serious consideration should be given to implementation of a public health programme of falls prevention as a cost-effective option that enables population-wide access to the intervention strategies., (© The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Published
- 2015
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23. On "Identifying items to assess methodological quality…" Armio-Olivo A, Cummings GC, Fuentes J, et al. Phys Ther. 2014;94:1272-1284.
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Maher CG, Elkins MR, Herbert RD, Moseley AM, Sherrington C, and Kamper SJ
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- Humans, Physical Therapy Modalities, Quality Assurance, Health Care, Randomized Controlled Trials as Topic standards, Research Design standards
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- 2014
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24. Effect of a multifactorial, interdisciplinary intervention on risk factors for falls and fall rate in frail older people: a randomised controlled trial.
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Fairhall N, Sherrington C, Lord SR, Kurrle SE, Langron C, Lockwood K, Monaghan N, Aggar C, and Cameron ID
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- Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Aging, Cooperative Behavior, Female, Geriatric Assessment, Humans, Interdisciplinary Communication, Male, Mental Health, Muscle Strength, Muscle, Skeletal physiopathology, New South Wales, Nutrition Assessment, Prospective Studies, Risk Assessment, Risk Factors, Time Factors, Accidental Falls prevention & control, Exercise Therapy, Frail Elderly, House Calls, Patient Care Team
- Abstract
Background: frail older people have a high risk of falling., Objective: assess the effect of a frailty intervention on risk factors for falls and fall rates in frail older people., Design: randomised controlled trial., Participants: 241 community-dwelling people aged 70+ without severe cognitive impairment who met the Cardiovascular Health Study frailty definition., Intervention: multifactorial, interdisciplinary intervention targeting frailty characteristics with an individualised home exercise programme prescribed in 10 home visits from a physiotherapist and interdisciplinary management of medical, psychological and social problems., Measurements: risk factors for falls were measured using the Physiological Profile Assessment (PPA) and mobility measures at 12 months by a blinded assessor. Falls were monitored with calendars., Results: participants had a mean (SD) age of 83.3 (5.9) years, 68% were women and 216 (90%) completed the study. After 12 months the intervention group had significantly better performance than the control group, after controlling for baseline values, in the PPA components of quadriceps strength (between-group difference 1.84 kg, 95% CI 0.17-3.51, P = 0.03) and body sway (-90.63 mm, 95% CI -168.6 to -12.6, P = 0.02), short physical performance battery (1.58, 95% CI 1.02-2.14, P ≤ 0.001) and 4 m walk (0.06 m/s 95% CI 0.01-0.10, P = 0.02) with a trend toward a better total PPA score (-0.40, 95% CI -0.83-0.04, P = 0.07) but no difference in fall rates (incidence rate ratio 1.12, 95% CI 0.78-1.63, P = 0.53)., Conclusion: the intervention improved performance on risk factors for falls but did not reduce the rate of falls., Trial Registration: ACTRN12608000250336., (© The Author 2013. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@ oup.com.)
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- 2014
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25. Predicting participation restriction in community-dwelling older men: the Concord Health and Ageing in Men Project.
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Fairhall N, Sherrington C, Cameron ID, Blyth F, Naganathan V, Clemson L, Le Couteur D, Handelsman DJ, Waite L, and Cumming RG
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- Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Cognitive Dysfunction psychology, Comorbidity, Dementia psychology, Disability Evaluation, Geriatric Assessment, Humans, Longitudinal Studies, Male, New South Wales, Quality of Life, Risk Factors, Sex Factors, Surveys and Questionnaires, Time Factors, Aging psychology, Independent Living, Social Participation
- Abstract
Background: participation restriction, defined as 'problems an individual may experience in involvement in life situations' (e.g. work and leisure), reflects difficulty functioning at a societal level and is a key component of disability. Our objective was to describe changes in participation in older men over a 2-year period and to identify baseline variables associated with participation and change in participation over the 2-year period., Methods: one thousand and three hundred and twenty-seven community-dwelling men aged 70 years or over who completed the baseline and 2-year follow-up phases of the Concord Health and Ageing in Men Project, a population-based cohort study in Sydney, Australia, were studied. Participation restriction and a range of other variables were measured using self-report and performance measures. Regression analyses were conducted to examine factors associated with participation and change in participation., Results: over the 2-year period, participation in life roles deteriorated in 47.3% (627/1,327) of men, stayed the same in 20.7% (275/1,327) and improved in the remainder (32.0%). Overall, there was a significant deterioration in participation (P < 0.001). Reduced participation at 2-year follow-up was significantly associated with the following baseline factors: age, more comorbidities, mild cognitive impairment or dementia, lower mood, weakness, slower gait, worse activities of daily living performance, driving and baseline participation score. These variables explained 56% of the variance in participation at 2 years., Conclusion: participation in life roles worsened over a 2-year period in some community-dwelling older men. A number of associated factors were identified, which may provide targets for intervention to improve participation among older men.
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- 2014
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26. Many randomized trials of physical therapy interventions are not adequately registered: a survey of 200 published trials.
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Pinto RZ, Elkins MR, Moseley AM, Sherrington C, Herbert RD, Maher CG, Ferreira PH, and Ferreira ML
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- Bibliometrics, Humans, Periodicals as Topic statistics & numerical data, Publishing statistics & numerical data, Retrospective Studies, Physical Therapy Modalities, Randomized Controlled Trials as Topic, Registries statistics & numerical data
- Abstract
Background: Clinical trial registration has several putative benefits: prevention of selective reporting, avoidance of duplication, encouragement of participation, and facilitation of reviews. Previous surveys suggest that most trials are registered. However, these surveys examined only trials in journals with high impact factors, which may bias the results., Purpose: This study examined the completeness of clinical trial registration and the extent of selective reporting of outcomes in a random sample of published randomized trials in physical therapy., Data Sources: This was a retrospective cohort study in which 200 randomized trials of physical therapy interventions were randomly selected from those published in 2009 and indexed in the Physiotherapy Evidence Database (PEDro), regardless of the publishing journal., Data Extraction: Evidence of registration was sought for each trial in the study, on clinical trial registers, and by contacting authors., Data Synthesis: The proportion of randomized trials that were registered was 67/200 (34%). This proportion was significantly lower than among the trials in journals with high impact factors, where the proportion was 75% (odds ratio=7.4, 95% confidence interval=2.6-21.4). Unambiguous primary outcomes (ie, method and time points of measurement clearly defined in the trial registry entry) were registered for 32 trials, and registration was adequate (ie, prospective with unambiguous primary outcomes) for 5/200 (2.5%) trials. Selective outcome reporting occurred in 23 (47%) of the 49 trials in which selective reporting was assessable., Limitations: The inclusion of only English-language trials prevents generalization of the results to non-English-language trials., Conclusions: Registration of randomized trials of physical therapy interventions is rarely adequate. Consequently, the putative benefits of registration are not being fully realized.
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- 2013
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27. Measures of physical functioning after hip fracture: construct validity and responsiveness of performance-based and self-reported measures.
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Farag I, Sherrington C, Kamper SJ, Ferreira M, Moseley AM, Lord SR, and Cameron ID
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- Aged, Aged, 80 and over, Female, Humans, Male, Mobility Limitation, Muscle Strength physiology, Outcome Assessment, Health Care, Postural Balance physiology, Psychometrics, Recovery of Function, Self Report, Surveys and Questionnaires, Task Performance and Analysis, Disability Evaluation, Hip Fractures rehabilitation, Hip Joint physiopathology
- Abstract
Objectives: this study aimed to investigate the construct validity and responsiveness of performance-based and self-reported measures of strength, mobility and balance after hip fracture., Design: secondary analysis of clinical trial data., Subjects: a total of 148 older people undergoing hip fracture rehabilitation., Methods: correlation coefficients assessed construct validity. Internal responsiveness was assessed by calculating effect sizes (ES) I and II. Area under the receiver operating characteristic curve (AUC) assessed external responsiveness with change in EuroQol as the reference., Results: correlations between performance-based and self-reported measures were small to medium (strength r = 0.17, mobility r = 0.45 and balance r = 0.37). The most responsive performance-based measures included walking speed (ESI 1.7, ESII 1.2), Physical Performance and Mobility Examination (ESI 1.3, ESII 1.0) and chair-rise test (ESI 1.1, ESII 0.8). Self-reported mobility (ESI 0.8, ESII 0.6) and strength (ESI 0.8, ESII 0.6) were more responsive than self-reported balance (ESI 0.3, ESII 0.2). External responsiveness (AUC) was greatest for walking speed (0.72) and lowest for the measures of body sway (0.53)., Conclusion: self-reported and performance-based indices appear to assess different constructs and may provide complementary information about physical functioning in people after hip fracture. Measures of strength and mobility showed greater ability to detect change than measures of balance.
- Published
- 2012
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28. Do exercise interventions designed to prevent falls affect participation in life roles? A systematic review and meta-analysis.
- Author
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Fairhall N, Sherrington C, Clemson L, and Cameron ID
- Subjects
- Activities of Daily Living, Aged, Aged, 80 and over, Humans, Outcome Assessment, Health Care, Randomized Controlled Trials as Topic, Rehabilitation methods, Accidental Falls prevention & control, Exercise Therapy, Life Style, Patient Participation
- Abstract
Background: the World Health Organization describes individuals' functioning at a societal level as 'participation'. Despite being a key component of functioning and an important goal of rehabilitation, participation is not measured consistently in ageing research. The aim was to evaluate the extent to which measurement of participation has been reported in trials of fall prevention interventions and to determine the effect of exercise interventions on participation in life roles., Methods: systematic review with meta-analysis. Randomised controlled trials of exercise interventions that aimed to reduce falls in older people (60+) in community, aged care facilities or hospital settings were included. The outcome of interest was participation in life roles. Trials that measured participation at two time-points were included in the meta-analysis., Results: ninety-six trials met the review inclusion criteria. Participation was measured in 19 of these trials (20%). Nine instruments were used to measure participation. Fifteen trials, involving 3,616 participants, were included in the meta-analysis. The pooled estimate of the effect of interventions including exercise indicated a small improvement in participation (Hedges' g = 0.16, 95% confidence interval = 0.04-0.27, P = 0.006). Meta-regression showed multifactorial intervention with an exercise component had a larger effect than exercise intervention alone, but the difference was not statistically significant (effect on Hedges' g = 0.22, 95% CI = -0.05 to 0.50, P = 0.10)., Conclusion: interventions including exercise may improve participation in life roles in older people. The International Classification of Functioning, Disability and Health may be a useful framework for understanding the broader impact of falls prevention interventions., Systematic Review Registration: ACTRN12610000862044.
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- 2011
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29. CENTRAL, PEDro, PubMed, and EMBASE are the most comprehensive databases indexing randomized controlled trials of physical therapy interventions.
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Michaleff ZA, Costa LO, Moseley AM, Maher CG, Elkins MR, Herbert RD, and Sherrington C
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- Humans, Review Literature as Topic, Abstracting and Indexing, Databases, Bibliographic, Physical Therapy Modalities, Randomized Controlled Trials as Topic statistics & numerical data
- Abstract
Background: Many bibliographic databases index research studies evaluating the effects of health care interventions. One study has concluded that the Physiotherapy Evidence Database (PEDro) has the most complete indexing of reports of randomized controlled trials of physical therapy interventions, but the design of that study may have exaggerated estimates of the completeness of indexing by PEDro., Objective: The purpose of this study was to compare the completeness of indexing of reports of randomized controlled trials of physical therapy interventions by 8 bibliographic databases., Design: This study was an audit of bibliographic databases., Methods: Prespecified criteria were used to identify 400 reports of randomized controlled trials from the reference lists of systematic reviews published in 2008 that evaluated physical therapy interventions. Eight databases (AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO, and PubMed) were searched for each trial report. The proportion of the 400 trial reports indexed by each database was calculated., Results: The proportions of the 400 trial reports indexed by the databases were as follows: CENTRAL, 95%; PEDro, 92%; PubMed, 89%; EMBASE, 88%; CINAHL, 53%; AMED, 50%; Hooked on Evidence, 45%; and PsycINFO, 6%. Almost all of the trial reports (99%) were found in at least 1 database, and 88% were indexed by 4 or more databases. Four trial reports were uniquely indexed by a single database only (2 in CENTRAL and 1 each in PEDro and PubMed)., Limitations: The results are only applicable to searching for English-language published reports of randomized controlled trials evaluating physical therapy interventions., Conclusions: The 4 most comprehensive databases of trial reports evaluating physical therapy interventions were CENTRAL, PEDro, PubMed, and EMBASE. Clinicians seeking quick answers to clinical questions could search any of these databases knowing that all are reasonably comprehensive. PEDro, unlike the other 3 most complete databases, is specific to physical therapy, so studies not relevant to physical therapy are less likely to be retrieved. Researchers could use CENTRAL, PEDro, PubMed, and EMBASE in combination to conduct exhaustive searches for randomized trials in physical therapy.
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- 2011
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30. Core journals that publish clinical trials of physical therapy interventions.
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Costa LO, Moseley AM, Sherrington C, Maher CG, Herbert RD, and Elkins MR
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- Bibliometrics, Databases, Bibliographic, Clinical Trials as Topic statistics & numerical data, Journal Impact Factor, Periodicals as Topic statistics & numerical data, Physical Therapy Modalities, Publishing statistics & numerical data
- Abstract
Objective: The objective of this study was to identify core journals in physical therapy by identifying those that publish the most randomized controlled trials of physical therapy interventions, provide the highest-quality reports of randomized controlled trials, and have the highest journal impact factors., Design: This study was an audit of a bibliographic database., Methods: All trials indexed in the Physiotherapy Evidence Database (PEDro) were analyzed. Journals that had published at least 80 trials were selected. The journals were ranked in 4 ways: number of trials published; mean total PEDro score of the trials published in the journal, regardless of publication year; mean total PEDro score of the trials published in the journal from 2000 to 2009; and 2008 journal impact factor., Results: The top 5 core journals in physical therapy, ranked by the total number of trials published, were Archives of Physical Medicine and Rehabilitation, Clinical Rehabilitation, Spine, British Medical Journal (BMJ), and Chest. When the mean total PEDro score was used as the ranking criterion, the top 5 journals were Journal of Physiotherapy, Journal of the American Medical Association (JAMA), Stroke, Spine, and Clinical Rehabilitation. When the mean total PEDro score of the trials published from 2000 to 2009 was used as the ranking criterion, the top 5 journals were Journal of Physiotherapy, JAMA, Lancet, BMJ, and Pain. The most highly ranked physical therapy-specific journals were Physical Therapy (ranked eighth on the basis of the number of trials published) and Journal of Physiotherapy (ranked first on the basis of the quality of trials). Finally, when the 2008 impact factor was used for ranking, the top 5 journals were JAMA, Lancet, BMJ, American Journal of Respiratory and Critical Care Medicine, and Thorax. There were no significant relationships among the rankings on the basis of trial quality, number of trials, or journal impact factor., Conclusions: Physical therapists who are trying to keep up-to-date by reading the best available evidence on the effects of physical therapy interventions have to read more broadly than just physical therapy-specific journals. Readers of articles on physical therapy trials should be aware that high-quality trials are not necessarily published in journals with high impact factors.
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- 2010
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31. Mobility training after hip fracture: a randomised controlled trial.
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Moseley AM, Sherrington C, Lord SR, Barraclough E, St George RJ, and Cameron ID
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- Activities of Daily Living, Aged, Aged, 80 and over, Cognition Disorders physiopathology, Exercise psychology, Female, Hip Fractures physiopathology, Hip Fractures psychology, Humans, Male, Mobility Limitation, Outcome Assessment, Health Care, Postural Balance physiology, Quality of Life, Exercise Therapy methods, Hip Fractures rehabilitation, Physical Therapy Modalities, Resistance Training methods
- Abstract
Objective: to compare the effects of two different exercise programmes after hip fracture., Design: assessor-blinded randomised controlled trial., Setting: hospital rehabilitation units, with continued intervention at home., Subjects: 160 people with surgical fixation for hip fracture transferred to inpatient rehabilitation., Method: in addition to other rehabilitation strategies, the intervention group received a higher dose (60 min/day) exercise programme conducted whilst standing and the control group received a lower dose exercise programme (30 min/day) primarily conducted whilst seated/supine. The primary outcome measures were knee extensor muscle strength in the fractured leg and walking speed, measured at 4 and 16 weeks., Results: 150 participants (94% of those recruited) completed the trial. There were no differences between the groups for the two primary outcome measures. Post hoc analyses revealed increased walking speed among those in the higher dose, weight-bearing exercise group with cognitive impairment at 4 and 16 weeks., Conclusions: there was no benefit (or harm) due to the higher dose, weight-bearing exercise programme with respect to the primary outcome measures. However, people with hip fracture and cognitive impairment gained greater benefit from the higher dose programme than from the lower dose programme.
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- 2009
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32. A description of the trials, reviews, and practice guidelines indexed in the PEDro database.
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Maher CG, Moseley AM, Sherrington C, Elkins MR, and Herbert RD
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- Evidence-Based Medicine, Humans, Internet, Practice Guidelines as Topic, Randomized Controlled Trials as Topic, Review Literature as Topic, Databases, Bibliographic, Physical Therapy Modalities
- Abstract
This perspective provides an overview of the randomized controlled trials, systematic reviews, and evidence-based clinical practice guidelines in physical therapy. Data from the Physiotherapy Evidence Database (PEDro) are used to describe key events in the history of physical therapy research and the growth of evidence of effects of interventions used in the various subdisciplines of physical therapy. The 11,494 records that were identified reveal a rich history of physical therapy research dating back to the first trial in 1929. Most of the randomized controlled trials, systematic reviews, and evidence-based clinical practice guidelines in physical therapy have been published since the year 2000. This rapid growth presents a challenge for physical therapists who want to keep up to date in clinical practice.
- Published
- 2008
- Full Text
- View/download PDF
33. The comparative ability of eight functional mobility tests for predicting falls in community-dwelling older people.
- Author
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Tiedemann A, Shimada H, Sherrington C, Murray S, and Lord S
- Subjects
- Accidental Falls statistics & numerical data, Aged, Aged, 80 and over, Aging, Databases, Factual, Feasibility Studies, Follow-Up Studies, Geriatric Assessment statistics & numerical data, Housing for the Elderly, Humans, Mobility Limitation, Postural Balance, Predictive Value of Tests, Prospective Studies, Reproducibility of Results, Risk Factors, Sensitivity and Specificity, Accidental Falls prevention & control, Disability Evaluation, Geriatric Assessment methods, Wounds and Injuries epidemiology, Wounds and Injuries prevention & control
- Abstract
Background: numerous tests have been suggested as fall risk indicators. However, the validity of these assessments has not been demonstrated in large representative samples of community-dwelling older people., Objective: the objective of this study was to examine the comparative ability and clinical utility of eight mobility tests for predicting multiple falls in older community-dwelling people., Methods: design--prospective cohort study; subjects--362 subjects aged 74-98 years; measurements--the sit-to-stand test with one and five repetitions, the pick-up-weight test, the half-turn test, the alternate-step test (AST), the six-metre-walk test (SMWT) and stair ascent and descent tasks. Falls were monitored for 1 year with fall calendars., Results: in the 12-month follow-up period, 80 subjects (22.1%) suffered two or more falls. Multiple fallers performed significantly worse than non-multiple fallers in the sit-to-stand test with five repetitions (STS-5), the AST, the half-turn test, the SMWT and the stair-descent test. When dichotomised using cut-off points from receiver-operated characteristics (ROC) curve analyses, these tests demonstrated reasonable sensitivity and specificity in identifying multiple fallers. A principal components analysis identified only one factor underlying the mobility tests. Poor performances in two mobility tests, however, increased the risk of multiple falls more than poor performance in one test alone (ORs = 3.66, 95% CI = 1.44, 9.27 and 1.61, 95% CI = 0.62, 4.16 respectively)., Conclusions: the mobility tests appear to be measuring a similar 'mobility' construct. Based on feasibility and predictive validity, the AST, STS-5 and SMWTs were the best tests.
- Published
- 2008
- Full Text
- View/download PDF
34. Home environment risk factors for falls in older people and the efficacy of home modifications.
- Author
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Lord SR, Menz HB, and Sherrington C
- Subjects
- Aged, Clinical Trials as Topic, Frail Elderly, Homes for the Aged, Humans, Protective Devices, Risk Factors, Safety Management, Accidental Falls prevention & control, Environment Design
- Abstract
Most homes contain potential hazards, and many older people attribute their falls to trips or slips inside the home or immediate home surroundings. However, the existence of home hazards alone is insufficient to cause falls, and the interaction between an older person's physical abilities and their exposure to environmental stressors appears to be more important. Taking risks or impulsivity may further elevate falls risk. Some studies have found that environmental hazards contribute to falls to a greater extent in older vigorous people than in older frail people. This appears to be due to increased exposure to falls hazards with an increase in the proportion of such falls occurring outside the home. There may also be a non-linear pattern between mobility and falls associated with hazards. Household environmental hazards may pose the greatest risk for older people with fair balance, whereas those with poor balance are less exposed to hazards and those with good mobility are more able to withstand them. Reducing hazards in the home appears not to be an effective falls-prevention strategy in the general older population and those at low risk of falls. Home hazard reduction is effective if targeted at older people with a history of falls and mobility limitations. The effectiveness may depend on the provision of concomitant training for improving transfer abilities and other strategies for effecting behaviour change.
- Published
- 2006
- Full Text
- View/download PDF
35. Challenges for evidence-based physical therapy: accessing and interpreting high-quality evidence on therapy.
- Author
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Maher CG, Sherrington C, Elkins M, Herbert RD, and Moseley AM
- Subjects
- Humans, Periodicals as Topic, Publication Bias, Randomized Controlled Trials as Topic, Evidence-Based Medicine, Information Systems, Physical Therapy Modalities
- Abstract
Although there is a growing awareness of evidence-based practice among physical therapists, implementation of evidence-based practice has proved difficult. This article discusses barriers to access and interpretation of evidence. Some solutions are offered, including facilitating the publication of all research, use of an optimum format for reporting research, maximizing the efficient use of electronic databases, improving physical therapists' skills in critical appraisal of published research, and fostering consumer access to evidence. These strategies and others discussed in the article might facilitate implementation of evidence-based physical therapy.
- Published
- 2004
36. Reliability of the PEDro scale for rating quality of randomized controlled trials.
- Author
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Maher CG, Sherrington C, Herbert RD, Moseley AM, and Elkins M
- Subjects
- Evidence-Based Medicine, Humans, Quality Control, Reproducibility of Results, Databases, Bibliographic, Physical Therapy Modalities, Randomized Controlled Trials as Topic standards
- Abstract
Background and Purpose: Assessment of the quality of randomized controlled trials (RCTs) is common practice in systematic reviews. However, the reliability of data obtained with most quality assessment scales has not been established. This report describes 2 studies designed to investigate the reliability of data obtained with the Physiotherapy Evidence Database (PEDro) scale developed to rate the quality of RCTs evaluating physical therapist interventions., Method: In the first study, 11 raters independently rated 25 RCTs randomly selected from the PEDro database. In the second study, 2 raters rated 120 RCTs randomly selected from the PEDro database, and disagreements were resolved by a third rater; this generated a set of individual rater and consensus ratings. The process was repeated by independent raters to create a second set of individual and consensus ratings. Reliability of ratings of PEDro scale items was calculated using multirater kappas, and reliability of the total (summed) score was calculated using intraclass correlation coefficients (ICC [1,1])., Results: The kappa value for each of the 11 items ranged from.36 to.80 for individual assessors and from.50 to.79 for consensus ratings generated by groups of 2 or 3 raters. The ICC for the total score was.56 (95% confidence interval=.47-.65) for ratings by individuals, and the ICC for consensus ratings was.68 (95% confidence interval=.57-.76)., Discussion and Conclusion: The reliability of ratings of PEDro scale items varied from "fair" to "substantial," and the reliability of the total PEDro score was "fair" to "good."
- Published
- 2003
37. An evaluation of footwear worn at the time of fall-related hip fracture.
- Author
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Sherrington C and Menz HB
- Subjects
- Aged, Aged, 80 and over, Evaluation Studies as Topic, Female, Hip Fractures etiology, Humans, Male, Middle Aged, Accidental Falls prevention & control, Hip Fractures prevention & control, Shoes adverse effects
- Abstract
Background: a range of footwear features have been shown to influence balance in older people, however, little is known about the relationships between inappropriate footwear, falls and hip fracture., Objectives: to describe the characteristics of footwear worn at the time of fall-related hip fracture and establish whether the features of the shoe influenced the type of fall associated with the fracture., Methods: 95 older people (average age 78.3 years, SD 7.9) who had suffered a fall-related hip fracture were asked to identify the footwear they were wearing when they fell. Footwear characteristics were then evaluated using a standardised assessment form. Information was also collected on the type and location of fall., Results: the most common type of footwear worn at the time of the fall was slippers (22%), followed by walking shoes (17%) and sandals (8%). Few subjects were wearing high heels when they fell (2%). The majority of subjects (75%) wore shoes with at least one theoretically sub-optimal feature, such as absent fixation (63%), excessively flexible heel counters (43%) and excessively flexible soles (43%). Subjects who tripped were more likely to be wearing shoes with no fixation compared to those who reported other types of falls [chi(2)=4.21, df=1, P=0.033; OR=2.93 (95%CI 1.03-8.38)]., Conclusions: many older people who have had a fall-related hip fracture were wearing potentially hazardous footwear when they fell. The wearing of slippers or shoes without fixation may be associated with increased risk of tripping. Prospective studies into this proposed association appear warranted.
- Published
- 2003
- Full Text
- View/download PDF
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