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Start Over Author "Alina Botgros" Publisher oxford university press (oup)
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1. Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Author

Luke B Snell, Adela Alcolea-Medina, Themoula Charalampous, Christopher Alder, Tom G S Williams, Flavia Flaviani, Rahul Batra, Prijay Bakrania, Rajeni Thangarajah, Stuart J D Neil, Claire van Nispen tot Pannerden, Alina Botgros, Emma Aarons, Samuel T Douthwaite, Jonathan D Edgeworth, and Gaia Nebbia

Subjects
Microbiology (medical), Infectious Diseases
Abstract

The management of coronavirus disease 2019 has become more complex due to the expansion of available therapies. The presence of severe acute respiratory syndrome coronavirus 2 variants and mutations further complicates treatment due to their differing susceptibilities to therapies. Here we outline the use of real-time whole genome sequencing to detect persistent infection, evaluate for mutations confering resistance to treatments, and guide treatment decisions.

Published
2022
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