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Start Over Author "Ana González Rinne" Publisher oxford university press (oup)
8 results on '"Ana González Rinne"'

1. Pretransplant evaluation and the risk of glucose metabolic alterations after renal transplantation: a prospective study

Author

Arminda Fariña-Hernández, Domingo Marrero-Miranda, Estefania Perez-Carreño, Antonia De Vera-Gonzalez, Alejandra González, Cristian Acosta-Sorensen, Ana Elena Rodríguez-Rodríguez, Tatiana Collantes, Marta del Pino García, Ana Isabel Rodríguez-Muñoz, Carla Rodriguez-Alvarez, Antonio Rivero, Manuel Macía, Elena Teran, Nuria V Sanchez-Dorta, Lourdes Perez-Tamajón, Alejandra Alvarez-González, Ana González-Rinne, Aurelio Rodríguez-Hernández, Eduardo De Bonis-Redondo, Concepción Rodriguez-Adanero, Domingo Hernández, Esteban Porrini, and Armando Torres

Subjects
Transplantation, Nephrology
Abstract

Background Post-transplant prediabetes (PreDM) and diabetes (PTDM) are common and have an impact on cardiovascular events. We sought to investigate the pathogenesis and best approach for prediction. Methods We prospectively studied 115 waitlisted patients from a single center without manifest diabetes. An oral glucose tolerance test (OGTT) was performed yearly until transplantation and 12 months later. Insulin secretion, insulin sensitivity (IS) and disposition index (DI) were derived from the OGTT. Results PreDM and PTDM were observed in 27% and 28.6% of patients, respectively. Pretransplant age, body mass index (BMI), 120 min glucose, IS, DI, and prediabetes or undiagnosed diabetes were significantly associated with these alterations. In multivariate analysis, pretransplant age [odds ratio (OR) 1.5; 95% confidence interval (CI) 1.04–2.1], BMI (OR 1.16; 95% CI 1.04–1.3) and cumulative steroids (OR 1.5; 95% CI 1.02–2.2) were predictors of PreDM or PTDM. Receiver operating characteristic curve analysis showed that pretransplant BMI and 120 min glucose had the highest area under the curve (0.72; 95% CI 0.62–0.8; and 0.69; 95% CI 0.59–0.79, respectively). The highest discrimination cut-off for BMI (≥28.5 kg/m2) and 120 min glucose (≥123.5 mg/dL) yielded a similar number needed to diagnose (2.5). Conclusions PreDM or PTDM develops in waitlisted patients with an ineffective insulin secretion and BMI shows a similar diagnostic capacity to OGTT. Pretransplant interventions may reduce post-transplant glucose alterations.

Published
2022

2. Early glomerular filtration rate changes in living kidney donors and recipients: an example of renal plasticity

Author

Ana González Rinne, Cristian Acosta Sorensen, Sergio Luis Lima, Marta Gómez Gil, Natalia Negrín Mena, Laura Díaz Martín, Ana Ramírez, Adelaida Morales, Nicanor Vega, Eduardo Gallego, Edduin Martín Izquierdo, Elisa Cabello, Ana Elena Rodríguez Rodríguez, Jesús Pimentel González, Beatriz Escamilla, Coriolano Cruz, Lourdes Pérez Tamajón, Armando Torres Ramírez, Flavio Gaspari, Alberto Ortiz, and Esteban Porrini

Subjects
Transplantation, Nephrology
Abstract

Background In living kidney transplantation there are two different individuals, a healthy donor and a renal transplant recipient. This is an excellent human model to study factors that influence kidney function in the context of reduced renal mass and the adaptation of two comparable kidneys to different metabolic demands. Methods We analyzed the changes in measured glomerular filtration rate (GFR, iohexol) from pretransplantation to 12 months after transplantation in 30 donor–recipient pairs. Each donor was compared with his/her recipient. We defined a priori three different groups based on GFR differences at 12 months: donor > recipient (Group A; 78 ± 8 versus 57 ± 8 mL/min), donor Results In Group A donors were mostly male and recipients were female (75% each). Donors had a higher baseline weight than their recipients. During follow-up, weight remained stable in donors but increased 7% in recipients. In Group B donors were mostly female (60%) and recipients male. At baseline, donors had a lower weight than recipients. At 12 months, weight was stable in donors but increased in recipients. In Group C donors were mostly (75%) female and recipients male. At baseline, donors had a higher BMI than their recipients. At 12 months, BMI was stable in donors but increased 14% in recipients. In multivariable analysis, higher GFR at 12 months was associated with higher baseline weight and GFR in donors and with male gender and higher baseline weight in recipients. Conclusions Kidneys from living donors are more ‘plastic’ than originally thought and respond to metabolic demands and weight changes of their new host. These changes should be taken into account when assessing GFR outcomes in this population.

Published
2022

3. Impact of errors of creatinine and cystatin C equations in the selection of living kidney donors

Author

Ana González-Rinne, Laura Díaz Martín, Esteban Porrini, Patricia García, Federico González-Rinne, Sergio Luis-Lima, Alejandra Alvarez, Lourdes Pérez-Tamajón, Natalia Negrín-Mena, Ana Aldea-Perona, Nicanor Vega, María Del Carmen Abad, Alejandra González-Delgado, Domingo Marrero-Miranda, Ana Ramirez, Armando Torres, Adelaida Morales, Beatriz Escamilla, Elisa Cabello, and Alejandro Jiménez-Sosa

Subjects
medicine.medical_specialty, 030232 urology & nephrology, Urology, Renal function, 030204 cardiovascular system & hematology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, living kidney donation, measured GFR, Transplantation, Creatinine, Plasma clearance, Kidney, Errata, biology, business.industry, Confidence interval, medicine.anatomical_structure, chemistry, Cystatin C, Nephrology, estimated GFR, biology.protein, Iohexol, business, Clearance, medicine.drug
Abstract

BackgroundReliable determination of glomerular filtration rate (GFR) is crucial in the evaluation of living kidney donors. Although some guidelines recommend the use of measured GFR (mGFR), many centres still rely on estimated GFR (eGFR) obtained through equations or 24-h creatinine clearance. However, eGFR is neither accurate nor precise in reflecting real renal function. We analysed the impact of eGFR errors on evaluation and decision making regarding potential donors.MethodsWe evaluated 103 consecutive living donors who underwent mGFR via iohexol plasma clearance and eGFR by 51 creatinine- and/or cystatin C–based equations. The cut-off for living donation in our centre is GFR > 80 mL/min for donors >35 years of age or 90 mL/min for those ResultsNinety-three subjects (90.3%) had mGFR values above (donors) and 10 [9.7% (95% confidence interval 5.4–17)] below (non-donors) the cut-off. In non-donors, most of the equations gave eGFR values above the cut-off, so donation would have been allowed based on eGFR. All non-donors were female with reduced weight, height and body surface. In donors, up to 32 cases showed eGFR below the cut-off, while mGFR was actually higher. Therefore an important number of donors would not have donated based on eGFR alone.ConclusionThe misclassification of donors around the cut-off for donation is very common with eGFR, making eGFR unreliable for the evaluation of living kidney donors. Whenever possible, mGFR should be implemented in this setting.

Published
2019

4. MO013PATERNAL SAFETY OF THE USE OF MYCOPHENOLIC ACID BY KIDNEY TRANSPLANT RECIPIENTS. RESULTS OF THE EMVARON STUDY

Author

Armando Coca, Ana González-Rinne, Paloma L Martin-Moreno, Mónica Pérez-Mir, Valero Rosalía, Ana Sánchez-Fructuoso, Carlos Jiménez, Marisa Mir, Isabel María López López, Ana Ventura Galiano, Leónidas Cruzado-Vega, Auxiliadora Mazuecos, Natalia Ridao, Ernesto José Fernández-Tagarro, and Nestor Toapanta

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, medicine, Urology, business, Kidney transplant, Mycophenolic acid, medicine.drug
Abstract

Background and Aims Mycophenolic acid (MPA) is one of the most used immunosuppressive drugs. It is teratogenic in women with a typical embryopathy profile. Regarding its effect on the children of male kidney transplant recipients, although clinical evidence does not indicate a greater risk of malformations, the European Medicines Agency and the Spanish Agency for Medicines and Health Products introduced in 2015 the recommendation to use contraceptive methods because of their genotoxic potential. For this reason, we propose to study the results of the Spanish Kidney Transplant Centers. Method Multicenter retrospective observational study in which 15 Kidney Transplant Centers have participated. Of 3934 men ≤ 60 years old that received a kidney transplant between 2000 and 2015, 3023 were contacted, and 159 men who fathered at least one post-transplant pregnancy (total 252 fetuses) were included. We compared the incidence of abortions and live births with malformations among those who received MPA at the time of conception vs. those who did not. Results In the 252 fetuses (characteristics in table 1) there was an exitus and no differences were detected in the incidence of abortions between the group exposed to MPA (n = 230) and the unexposed group (n = 22), 11.3% vs 18.2%, p = 0.31. Among the 221 live-born fetuses, no differences were found in congenital malformations between the group exposed to MPA (n = 203) and the unexposed (n = 18) 4.9% vs. 16.7%, p = 0.07. Among the malformations described, the typical embryopathy profile of the MPA was not found. Conclusion According to the data of this retrospective national multicenter study, the use of MPA in male kidney transplant recipients does not cause a greater number of abortions or congenital malformations. For these reasons, and given the evidence also published by other groups, it seems necessary to reevaluate the recommendation given on contraception in men treated with MPA.

Published
2020

5. SP265THE ESTIMATION OF GFR AND THE ADJUSTMENT FOR BSA IN OVERWEIGHT AND OBESITY: A DREADFUL COMBINATION OF TWO ERRORS

Author

Esteban Porrini, Rosa Miquel, Domingo Marrero-Miranda, Maru Navarro, Marina López-Martínez, Sergio Luis-Lima, Laura Díaz-Martín, Enrique Morales, Natalia Negrín-Mena, Marian Cobo, Alejandra González-Delgado, Beatriz Escamilla, Armando Torres, Federico González-Rinne, Patricia Delgado-Mallén, and Ana González-Rinne

Subjects
Estimation, Transplantation, Nephrology, business.industry, Environmental health, medicine, Overweight, medicine.symptom, medicine.disease, business, Obesity
Published
2019

6. Transplantation - clinical II

Author

Handan Ozdemir, Himanshu V Patel, Tingli Wang, Izumi Yamamoto, Anna Perri, Eva Svobodova, Alberto Mella, Alexander Kildushevsky, Ole Øyen, Nicolas Congy-Jolivet, Sergio Luis-Lima, Yuangao Zou, Hideki Fuji, Tolga Yildirim, Norihiko Goto, Marian Klinger, Leonídio Dias, Won Seok Yang, Lanlan Wang, Tatjana Cvetkovic, Barbara Assenzio, Filiz Bakar, Samantha Mantovani, Halil Yazici, Vijay Thanaraj, Priyadarshini S Shah, Solbjørg Sagedal, Francesca Sidoti, Anupma Kaul, Giordano Zampi, Dharmendra Bhadauria, Moncef Mokni, Tatjana Jevtovic Stoimenov, Tine Thurison, Alessia Di Nauta, Christos S. Katsouras, Franca Sinesi, Denisa Mendonça, Jude Yagan, Atsushi Miki, Giorgos Spanos, F. Zalamea Jarrin, Maria Cristina Di Vico, Francesca Greco, Marco Ballestri, Veena R Shah, Takashi Yokoo, António Castro Henriques, Pranjal R Modi, Vito Fanelli, Andrey Vatazin, Jiri Fronek, Siren Sezer, Anna Teresa Mazzeo, Takayuki Yamamoto, Karen Stopper, Jerzy Chudek, Antonij Slavcev, Deepak Shankar Ray, Takaaki Kimura, Claudio Musetti, Christina Dörje, Lidija Orlić, Osman Ilhan, Rahmi Yilmaz, Francesca Damiano, Mehmet Gokhan Caglayan, Marcel Naik, Ken Kitamura, Maarten B. Rookmaaker, Arjan D. van Zuilen, Pablo Raffaele, Trond Jenssen, Yosu Luque, Masato Fujisawa, Katerina K. Naka, Giuseppe Paolo Segoloni, Ioannis Gkirdis, Leonardo Caroti, Maarten Naesens, Klemens Budde, Rossana Cavallo, Nanna von der Lippe, Ilaria Mastromauro, A. Azzebi, Rigas Kalaitzidis, Fredrik B. Brekke, António Cabrita, Sławomir Zmonarski, Flavio Vincenti, Alessandro De Vincenzi, Hela Ghezaiel, Vasilis Koutlas, Elena Cremaschi, Dorota Kamińska, Mark A. J. Devonald, Kostas C. Siamopoulos, Mahmut Altindal, Mehtap Ekmen Uyar, Dobrin Svinarov, Abdulrahman Housawi, Sanjin Rački, Wissal Sahtout, Ramazan Cetinkaya, Emre Tutal, Luísa Lobato, Mehmet Sukru Sever, Umberto Maggiore, Momir Mikov, Dorry L. Segev, Inés Beired Val, Stefania Bussolino, Fernando Gil Catalinas, Steffen Thiel, Anna Kotsia, Olesja Rissling, Halil Ermis, Borelli K. Zlatkov, Adam Varga, Efrat Harel, Eva Pokorna, P. Chudoba, Saliha Uyanık, Kostas Pappas, Maria Vittoria Mauro, Viktorija Dragojevic-Simic, Alexey Zulkarnaev, Vural Taner Yilmaz, Mikiko Yoshikawa, Luciana Mascia, Aureliusz Kolonko, Yasunaru Sakuma, Manoj R Gumber, Jens Bollerslev, Maria Boratyńska, Kathy Denesyk, Lionel Rostaing, Fabrizio Fop, Carlo Massimetti, Tak Mao Chan, Jamal Rizvi, Predrag Vlahovic, Anna Maria Degli Antoni, Yasuo Takeuchi, Bård Waldum, Pieter Evenepoel, Dai Kohguchi, Aurelio Rodríguez-Hernández, Marcin Protasiewicz, Yudo Tannno, Samira Ben Amor, Sofia Pedroso, Rusudana Kantaria, Nikola Stefanović, Renzo Bonofilgio, Kristin Godang, Hans-H. Neumayer, Aydin Turkmen, Bosiljka Devcic, Oktawia Mazanowska, Tomasz Dawiskiba, Zeynep Bal, Donatella Vizza, J. Portoles Perez, Maggie Ming Yee Mok, Veronika Fedulkina, Josefina Santos, Byung Ha Chung, Altagracia Bello Ovalle, Lampros Lakkas, Jean-Luc Taupin, Anis Belarbia, Anil Chandraker, Andrea Ranghino, Sharmas Vali, Yaeni Kim, Yong-Soo Kim, Dorota Bartoszek, Sakuma Yasunaru, Mirosław Banasik, Malgorzata Kaminska, Cheol Whee Park, Jonathan Visentin, Fulvia Giaretta, Nobuo Tsuboi, Nathan T. James, Tiziana Cena, Tri Q. Nquyen, Giovanni Piotti, Huseyin Kocak, Armando Torres, Milagros Sierra Carpio, Gabriela Pimentel Guzmán, O. Lafuente Covarrubias, B. Sanchez Sobrino, Yuliya V Smedbraaten, Morten W. Fagerland, Pankaj R Shah, Amin Amro, Maria Granito, Davide Diena, Hargovind L Trivedi, Kenan Keven, Hyuk Y Kwon, Bei Cai, Alena Parikova, Ercan Turkmen, Jean J. Filipov, Marc-Olivier Timsit, Alastair Ferraro, Nicoline M.H. Veldhuijzen, Ibrahim Aliosmanoglu, Koji Nanmoku, R K Sharma, Neven Vavic, Anders Hartmann, Nilgun Aysuna, Geir Mjøen, Barbara Sandor, Gianni Cappelli, Louise Moist, José-Carlos Oliveira, Salima Kejji, Alena Verflova, Haralampos Harisis, Babak J. Orandi, Cristina Izzo, Andras Toth, Ana González-Rinne, Ivana Mikolašević, Mehmet Haberal, Petra Reinke, Akimitsu Kobayashi, Marion Rabant, Agnieszka Sas, Giulia Ligabue, Soumava Gupta, Dmytro Khadzhynov, Soon Bae Kim, Fatih Yılmaz, Gunilla Høyer-Hansen, Fotios Zarzoulas, Semra Bozfakioglu, O. Guliyev, Mehtap Erkmen Uyar, Yasuyuki Nakada, Zeynep Kendi Celebi, Alejandro Jiménez-Sosa, Christophe Legendre, Haralampos Pappas, José Davide, Sandro Feriozzi, Keitaro Yokoyama, Mustafa Arici, Esteban Porrini, Niraj M. Desai, Dany Anglicheau, Enrico Eugenio Minetti, Shunji Narumi, Federica Civiletti, Bahar Gurlek Demirci, Pierre Merville, Pablo Klin, Natalia Negrín-Mena, Roberta Fenoglio, Pratik Das, Marco Quaglia, Abdelatif Achour, Martina Pavletic Persic, Turan Colak, Hallvard Holdaas, Hyun Seon Kim, Charlie Martinez, Nemanja Jacimovic, Sung H Son, Carlo Buzio, Francesco Fontana, Giorgos Tzeltzes, Anders Åsberg, Andrea Kantor, Sébastien Lepreux, Ana Aldea-Perona, Laure-Hélène Noël, Takafumi Yamakawa, Daniela Perugini, Magdalena Szotowska, Ichiro Ohkido, Antonio Gil Paraíso, Aruna V Vanikar, Nurhan Ozdemir Acar, Manuela Guedes de Almeida, Bo Ying Choy, Charles S. Craik, Antoine Bello, Andrzej Wiecek, Bang-Gee Hsu, Massimo Rittà, Cristina Giraldi, Björn Meijers, Gwendaline Guidicelli, Henri Kreis, Chul Woo Yang, Augusto Vaglio, Marit Elizabeth Von Düring, Kouji Nannmoku, Riccardo Magistroni, Yunus Erdem, Katrien De Vusser, Marta Artamendi Larrañaga, Hiroyasu Yamamoto, Luigi Biancone, Giorgos Nakas, Rita Marcela Fortunato, Enma Huarte Loza, Nemanja Rancic, Andrea Airoldi, Katarzyna Koscielska-Kasprzak, Francesca Leone, Kazunari Yoshida, R. Llopez Carratala, Miyeon Kim, Andrea Cossarizza, Gabriele Guglielmetti, G. Tognarelli, Burak Sayin, José Manuel González-Posada, Jin Kong, Bulent Altun, Ingrid Os, Anne Theakstone, Shantanu Bhattacharjya, Piotr Kuczera, Gian Domenico D Fabbri, Lionel Couzi, Yosra Guedri, Nurhan Ozdemir, Cristina Costa, Chung Hee Baek, Emil P. Dimitrov, Ester Gallo, Dirk Kuypers, Hermann Hernandez Vargas, Massimo Gai, Rohit Rungta, Jun-Seok Kim, Piero Stratta, Takashi Yagisawa, Cihat Burak Sayin, Antonio Amoroso, Faisal Rehman, Maria Zanazzi, P. Dominguez Apiñaniz, Teresa Papalia, Franco Brescia, Vesna Lukenda, Ruben Poesen, Gea Imperato, P. Carta, Davide Medica, Alessandra Palmisano, S. Karsten Alvarez, Rozenn Clément, Jelena Katic, F Ersoy, Vladimir Hanzal, Safa Nouira, Manisha Sahay, K. Kalmár-Nagy, Michele Battista, Eun J Whang, Kalman Toth, Andrew A. House, Anna Varberg Reisæter, Hyung Jin Cho, Evangelia Dounousi, Irini Tzalavra, Sabri Ferdaws, Gultekin Suleymanlar, Limei Luo, Ayhan Dinckan, Ilaria Deambrosis, Begum Erdemir, Akinori Nukui, Thomas Schachtner, Karsten Midtvedt, Cecilia Dall Anesse, Ewelina Sikora-Grabka, Domingo Marrero, Ming-Che Lee, Vivek B Kute, Lourdes Pérez-Tamajón, Ana Coloma Lopez, Maria Messina, Ozgur Akin Oto, Lorraine Kwan, Robert A. Montgomery, Aris Bechlioulis, Olga Balafa, Isabel Fonseca, Aida Larti, Magdalena Krajewska, Akira Kurosawa, Toshihisa Iwabuchi, Janka Slatinska, Teppei Ohyama, Agnieszka Hałoń, Daisuke Ishii, Dag Olav Dahle, Su-Kil Park, Soumaya Ben Abdelkrim, Won Y Choi, Fatma Nurhan Ozdemir Acar, Sanda Mrabet, Lorenzo Di Maria, Saliha Yildirim, Oliver Staeck, Aleksandra Kovacevic, Elisa Buti, Yasar Caliskan, Lampros K. Michalis, Makoto Tsujita, Paweł Madej, Michalis Mitsis, Eduardo Salido, Ondrej Viklicky, Kiranmai Ismal, Yoshihiko Watarai, Dimitris Evangelou, Hege Pihlstrøm, Dorsaf Zellama, Chul Soo Yoon, Radmila Veličković Radovanović, Thomas Bachelet, Duck Jong Han, Paolo Gigliotti, Shinichi Nishi, Danilo Lofaro, Nassim Kamar, Fabian Halleck, Charlotte Ng, Erik H. Strøm, Aki Mafune, Sara De Biasi, Selami Kocak Toprak, António Castro-Henriques, Fabiola Pagani, Alaattin Yildiz, Marcin Adamczak, Pablo Bridoux, Marina Colic, Anara Amanova, Kyeong Woo Nho, Anna V. Reisæter, Bum Soon Choi, Hugo Sanabria, Enrique Ramalle Gómara, Ayse Serra Artan, Walther H. Boer, Takahisa Hiramitsu, Narayan Prasad, Albane Sartorius, Juan De Francesco, Daniele Cagna, Jorge Malheiro, Himmet Bora Uslu, Alun Williams, Vincenzo Cantaluppi, Yunying Shi, La Salete Martins, Pål-Dag Line, Péter Szakály, and Takaaki Kobayashi

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, Medicine, business, Surgery
Published
2012

7. SP739CAN WE TRUST IN ESTIMATED GFR DECLINE IN RENAL TRANSPLANTION? THE NEPHROLOGIST IN THE MIST

Author

Laura Díaz-Martín, Domingo Marrero-Miranda, Armando Torres, Federico González-Rinne, Natalia Negrín-Mena, Esteban Porrini, Alejandra González-Delgado, Ana González-Rinne, and Sergio Luis-Lima

Subjects
Nephrology, Transplantation, medicine.medical_specialty, business.industry, Internal medicine, Emergency medicine, medicine, Mist, Renal function, business
Published
2017

8. MP799CAN WE TRUST ESTIMATED GLOMERULAR FILTRATION RATE N THE EVALUATION OF LIVING KIDNEY DONORS?

Author

Federico González-Rinne, Lourdes Pérez-Tamajón, Esteban Porrini, Alejandra González-Delgado, Armando Torres, Ana Aldea-Perona, Laura Díaz-Martín, Ana González-Rinne, Natalia Negrín-Mena, and Sergio Luis-Lima

Subjects
Transplantation, Kidney, medicine.medical_specialty, medicine.anatomical_structure, Nephrology, business.industry, medicine, Urology, Renal function, business
Published
2017

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