1. Decreased Invasive Capacity of Quinolone‐ResistantEscherichia coliin Patients with Urinary Tract Infections
- Author
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Juan Pablo Horcajada, Jordi Vila, José Antonio Martínez, María Velasco, Antonio Moreno Martinez, Margarita Barranco, Gloria Roig, José Mensa, Eladio Soriano, and Joaquim Ruiz
- Subjects
Adult ,Male ,Microbiology (medical) ,medicine.medical_specialty ,medicine.drug_class ,Urinary system ,Prostatitis ,Bacteremia ,Microbial Sensitivity Tests ,Urine ,medicine.disease_cause ,Gastroenterology ,Anti-Infective Agents ,Internal medicine ,Cystitis ,Drug Resistance, Bacterial ,Escherichia coli ,medicine ,Humans ,Outpatient clinic ,Escherichia coli Infections ,4-Quinolones ,biology ,business.industry ,Incidence (epidemiology) ,Middle Aged ,Quinolone ,medicine.disease ,biology.organism_classification ,Enterobacteriaceae ,Culture Media ,Blood ,Infectious Diseases ,Urinary Tract Infections ,Immunology ,Female ,business - Abstract
Quinolone-resistant (QR) Escherichia coli may have lower invasive capacity than does quinolone-susceptible E. coli. To evaluate this, we prospectively collected data regarding all cases of E. coli invasive urinary tract infections (IUTI) in 669 adults admitted to the Infectious Diseases Unit of our hospital during a 3-year period, as well as 10,950 patients with cystitis or asymptomatic bacteriuria who presented to the outpatient clinic during a 1-year period. QR E. coli was isolated in 20% of patients with cystitis, compared with 8% of those with IUTI (P
- Published
- 2001