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An experiment involving 33 pigs initially weighing 18 kg, was conducted to investigate the effects of a single intramuscular injection of the effects of a single intramuscular injection of selenium (sodium selenite) at different levels on resulting blood and tissue selenium concentrations at various time intervals post-injection and to determine the effect of a single lethal injectable dosage of selenium. Serum samples were collected and analyzed for SGOT and selenium. Hepatic, kidneys and longissimus muscle tissues were collected and analyzed for selenium. The same tissues were collected from those pigs dying of selenosis. Pigs receiving selenium injections of 1.65 to 3.30 mg/kg BW died of selenosis within 4 hr to 6 days with death occurring earlier at the higher dosage levels. Symptoms in order of occurrence were: vomiting, blind staggers, foaming at the mouth, dyspnea, prostration and death. Elevated SGOT activity was observed in the remaining injected pigs at 12 hr post-injection with the enzyme activity increasing as the dosage quantity increased, suggesting mild selenium toxicosis of body tissues.