1. Babelomics 5.0: functional interpretation for new generations of genomic data
- Author
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Luz Garcia-Alonso, Joaquín Dopazo, Francisco García-García, Ignacio Medina, Rubén Sánchez, Roberto Alonso, Alejandro Alemán, Joaquín Tárraga, Marta Bleda, Pablo Marin-Garcia, David Montaner, Marta R. Hidalgo, Daniel Perez-Gil, José Carbonell-Caballero, Alba Sanchis-Juan, Rosa D. Hernansaiz-Ballesteros, Alicia Amadoz, Francisco Salavert, and Cankut Çubuk
- Subjects
Interface (computing) ,Genomics ,Context (language use) ,Biology ,03 medical and health sciences ,0302 clinical medicine ,Software ,User experience design ,Neoplasms ,Genetics ,Web Server issue ,030304 developmental biology ,Internet ,0303 health sciences ,Information retrieval ,Sequence Analysis, RNA ,business.industry ,Gene Expression Profiling ,High-Throughput Nucleotide Sequencing ,Visualization ,The Internet ,business ,030217 neurology & neurosurgery ,Network analysis - Abstract
Babelomics has been running for more than one decade offering a user-friendly interface for the functional analysis of gene expression and genomic data. Here we present its fifth release, which includes support for Next Generation Sequencing data including gene expression (RNA-seq), exome or genome re-sequencing. Babelomics has simplified its interface, being now more intuitive. Improved visualization options, such as a genome viewer as well as an interactive network viewer, have been implemented. New technical enhancements at both, client and server sides, makes the user experience faster and more dynamic. Babelomics offers user-friendly access to a full range of methods that cover: (i) primary data analysis, (ii) a variety of tests for different experimental designs and (iii) different enrichment and network analysis algorithms for the interpretation of the results of such tests in the proper functional context. In addition to the public server, local copies of Babelomics can be downloaded and installed. Babelomics is freely available at: http://www.babelomics.org.
- Published
- 2015
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