1. BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK
- Author
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Pearce, Fiona A., Rutter, Megan, Sandhu, Ravinder, Batten, Rebecca L, Garner, Rozeena, Little, Jayne, Narayan, Nehal, Sharp, Charlotte A., Bruce, Ian N., Erb, Nicola, Griffiths, Bridget, Guest, Hannah, Macphie, Elizabeth, Packham, Jon, Hiley, Chris, Obrenovic, Karen, Rivett, Ali, Gordon, Caroline, and Lanyon, Peter C.
- Subjects
Rheumatology ,Pharmacology (medical) - Abstract
Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal for belimumab, and NHS England's clinical commissioning policy for rituximab. Methods: SLE cases attending outpatient clinics during any 4-week period between February and June 2018 were retrospectively audited to assess care at the preceding visit. The effect of clinical environment (general vs dedicated CTD/vasculitis clinic and specialized vs non-specialized centre) were tested. Bonferroni's correction was applied to the significance level. Results: Fifty-one units participated. We audited 1021 episodes of care in 1003 patients (median age 48 years, 74% diagnosed >5 years ago). Despite this disease duration, 286 (28.5%) patients had active disease. Overall in 497 (49%) clinic visits, it was recorded that the patient was receiving prednisolone, including in 28.5% of visits where disease was assessed as inactive. Low documented compliance (
- Published
- 2021