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1. MO213: Sars-COV-2 Vaccination DID Not Affect the Clinical Course of IGA Nephropathy in Latvian Adult Cohort

Author

Kārlis Rācenis, Anna Jana Saulīte, Anna Popova, Mikus Saulīte, Juta Kroiča, Aivars Petersons, Harijs Cernevskis, Aivars Lejnieks, Kristīne Oļeiņika, Baiba Šlisere, Janis Seilis, and Viktorija Kuzema

Subjects
Transplantation, Nephrology
Abstract

BACKGROUND AND AIMS The current strategy to fight against the COVID-19 pandemic involves active patient vaccination. Patients with renal and autoimmune diseases are in high risk for severe COVID-19 infection [1]. Therefore they should be prioritized for vaccination. Immunoglobulin A nephropathy (IgAN) is one of the most common primary glomerulonephritis triggered by mucous membrane alteration; however, there is a discussion about vaccination-caused IgA flare [2]. The immunological nature of IgAN and misleading information in public sources leaves patients skeptical about whether to get vaccinated [3]. The study aimed to investigate the impact of SARS-CoV-2 vaccination on the clinical course of IgA nephropathy. METHOD Adult patients treated in Pauls Stradins Clinical University Hospital with morphologically proven IgAN were included in the study. Patients with secondary IgAN were excluded. Evaluation of clinical and laboratory markers was performed on inclusion visit and on the second visit 6 months later. SARS-CoV-2 vaccination type and status were noted on both visits. Estimated GFR was calculated with CKD-EPI creatinine–cystatin equation. IBM SPSS Statistics version 27 and Microsoft Excel 10 were used for data analysis. RESULTS The study involved 54 patients, 36 were unvaccinated and 18 were fully vaccinated. A significant difference between the two groups was observed by baseline proteinuria. Other differences were not observed. Fourteen patients were vaccinated with mRNA vaccine, 13 with Comirnaty and 1 with Spikevax, and four patients were vaccinated with Vaxzevria vector vaccine. The differences between the two groups are shown in Table 1. During study period, two patients had COVID-19 infection; a patient in the vaccinated group had COVID-19 prior to vaccination. CONCLUSION SARS-CoV-2 vaccination did not affect the clinical course of IgA nephropathy. Our study results indicate that SARS-CoV-2 vaccination in IgA nephropathy patients was safe regarding renal function and disease activity markers.

Published
2022
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2. MO405: Leucine-Rich Alpha-2-Glycoprotein as a Potential Marker of Mesangial Cell Proliferation in Immunoglobulin a Nephropathy

Author

Anna Popova, Kārlis Rācenis, Viktorija Kuzema, Anna Jana Saulīte, Mikus Saulīte, Renārs Broks, Kristīne Oļeiņika, Baiba Šlisere, Aivars Petersons, Arvydas Laurinavicius, Harijs Cernevskis, Aivars Lejnieks, and Juta Kroiča

Subjects
Transplantation, Nephrology
Abstract

BACKGROUND AND AIMS Leucine-rich alpha-2-glycoprotein (LRG1) is a novel proangiogenic factor involved in the abnormal angiogenesis and renal fibrosis in diabetic nephropathy by potentiating endothelial transforming growth factor-beta/activin receptor-like kinase 1 (TGF-β/ALK1) signalling [1]. TGF-β mediates mesangial matrix accumulation culminating in the development of glomerulosclerosis [2], which also occurs in immunoglobulin A nephropathy (IgAN) patients. Our study aims to evaluate LRG1 as a marker of mesangial cell proliferation in IgAN patients. METHODS: Adults with a morphologically confirmed IgAN by the presence of IgA deposits by immunofluorescence microscopy were included in the study. Diabetes mellitus, oncology, acute inflammation processes were exclusion criteria. Serum LRG1 was detected using ELISA. RESULTS A total of 73 patients with IgAN were included [mean age 41 years, interquartile range (IQR) 35–47; range, 21–65; 65.8% men]. The median estimated glomerular filtration rate (eGFR) was 44 (IQR 24–83, range 4–133) mL/min/1.73m2. Kidney biopsies were analyzed according to the Oxford classification: M0 in 10 (13,7%), M1 in 56 (76.7%) patients. The median serum LRG1 was 49 µg/mL (IQR 40.7–57.7, range 29–133.3). Bivariate analyses showed that plasma LRG1 was negatively associated with eGFR (rho = −0.342, P = 0.003). A linear model showed that GFR decline for 1 mL/min was associated with an increase of LRG1 for 0.194 µg/mL. In IgAN patients with an M1-score LRG1 was higher (P = 0027, Mann–Whitney U test), the area under the ROC curve value for serum LRG1 was 0.739. CONCLUSION Serum LRG1 increases with GFR decline in patients with IgAN and at the same time correlates with mesangial hypercellularity according to Oxford classification. Therefore, LRG1 might be a potential marker of advanced disease in IgAN.

Published
2022
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3. MO405: Leucine-Rich Alpha-2-Glycoprotein as a Potential Marker of Mesangial Cell Proliferation in Immunoglobulin a Nephropathy

Author

Popova, Anna, primary, Rācenis, Kārlis, additional, Kuzema, Viktorija, additional, Jana Saulīte, Anna, additional, Saulīte, Mikus, additional, Broks, Renārs, additional, Oļeiņika, Kristīne, additional, Šlisere, Baiba, additional, Petersons, Aivars, additional, Laurinavicius, Arvydas, additional, Cernevskis, Harijs, additional, Lejnieks, Aivars, additional, and Kroiča, Juta, additional

Published
2022
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4. MO213: Sars-COV-2 Vaccination DID Not Affect the Clinical Course of IGA Nephropathy in Latvian Adult Cohort

Author

Rācenis, Kārlis, primary, Jana Saulīte, Anna, additional, Popova, Anna, additional, Saulīte, Mikus, additional, Kroiča, Juta, additional, Petersons, Aivars, additional, Cernevskis, Harijs, additional, Lejnieks, Aivars, additional, Oļeiņika, Kristīne, additional, Šlisere, Baiba, additional, Seilis, Janis, additional, and Kuzema, Viktorija, additional

Published
2022
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5. MO945SERUM AND URINE LEUCINE RICH ALPHA-2-GLYCOPROTEIN-1 IS ASSOCIATED WITH KIDNEY TRANSPLANT INJURY AND FAILURE

Author

Kārlis Rācenis, Aivars Lejnieks, Juta Kroiča, Ieva Ziedina, Aivars Petersons, Harijs Cernevskis, Aiga Vasiļvolfa, Anna Popova, Viktorija Kuzema, Baiba Šlisere, and Inese Folkmane

Subjects
Transplantation, medicine.medical_specialty, Proteinuria, business.industry, Urine, Kidney transplant, Endocrinology, Nephrology, Internal medicine, medicine, Prednisolone, Graft survival, Leucine rich alpha 2 glycoprotein, medicine.symptom, business, medicine.drug
Abstract

Background and Aims Kidney transplantation is the treatment of choice for most of the patients with end stage chronic kidney disease. To improve patient and graft survival, early diagnostics and discovery of specific biomarkers is important. Leucine rich alpha-2-glycoprotein-1 (LRG-1) is an innovative, non-invasive biomarker that is elevated in case of angiogenesis, inflammation and kidney injury. Aim was to evaluate biomarker LRG-1 level in serum and urine in kidney transplant recipients in accordance with kidney injury markers and time period after kidney transplantation. Method In the study 35 patients were enrolled. Patients had functioning kidney grafts and they were more than one year post transplant. We detected patient serum and urine LRG-1 levels, using ELISA. Correlation between serum LRG-1, urine LRG-1 and kidney graft structural and functional damage markers was performed. Also, we compared serum LRG-1 levels between subgroups (patients >5 years post transplant and ≤ 5 years post transplant). Results Serum LRG-1 had positive correlation with serum cystatin-C (r=0,46, p5 years post transplant had higher serum LRG-1 level compared with patients ≤5 years post transplant (p Conclusion Higher serum LRG-1 level correlates with decreased kidney transplant function and with longer time period after transplantation. Higher LRG-1 level in serum and urine is related to kidney transplant injury and failure. Urine LRG-1 can be a useful biomarker for tubular dysfunction in kidney transplant recipients.

Published
2021
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7. P1516 Detecting right ventricular systolic dysfunction in patients with acute ST-elevation myocardial infarction: echocardiography is good enough

Author

A Lejnieks, K Pickurs, Z Pickure, A Kalinin, M N Alekhin, and E Zakharova

Subjects
Right ventricular systolic dysfunction, medicine.medical_specialty, St elevation myocardial infarction, business.industry, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, In patient, General Medicine, Cardiology and Cardiovascular Medicine, business
Abstract

Background Many recent years" studies confirm the impact of the right ventricle (RV) dysfunction on morbidity and mortality in patients with an acute ST segment elevation myocardial infarction (STEMI). Earlier echocardiography (Echo) was not accurate enough in detecting RV dysfunction. The newest Echo methods allow to directly and accurately assess the RV systolic function. Purpose The aim of this study was to estimate the frequency of both RV segmental and global dysfunction in patients with STEMI using three-dimensional (3D) Echo and myocardial longitudinal strain (LS). Methods A group of 73 patients with first-time acute STEMI of different localization was selected. A control group of 32 people was formed of healthy individuals. As a standard for determining RV systolic dysfunction, changes in the traditional Echo parameters of the RV were accepted. In our study RV 3D ejection fraction (EF) less than 49% (AUC = 0.88, p Results RV involvement in patients with STEMI was found in 26%, if estimation was only visual (presence of segmental and/or global dysfunction). By adding in algorithm pathologically changed conventional Echo parameters, RV dysfunction was detected already in 36% of cases. New Echo parameters (3D RV EF and RV LS) added 6% more to RV involvement cases, resulting in 42% in total, if current guideline-recommended pathological cut-off levels were used. But the highest number of RV involvement cases - 62%, was reached, if visual evaluation and conventional Echo parameters were combined with 3D RV EF and RV LS, using higher pathology cut-off levels, defined in our study. This number is much closer to the data, provided by cardiac magnetic resonance and autopsy. Conclusion Modern echocardiography can provide greatly improved RV dysfunction diagnostics. In the case of STEMI current echocardiography methods show much closer results to the gold standard – cardiac magnetic resonance imaging and autopsy data, detecting RV involvement in more than 60% cases of acute STEMI.

Published
2020
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8. Polymorphisms in MEN1 and DRD2 genes are associated with the occurrence and characteristics of pituitary adenomas

Author

Liene Nikitina-Zake, Ligita Arnicane, Aivars Lejnieks, Inga Balcere, Vita Rovite, Andra Valtere, Raitis Peculis, Janis Stukens, Kaspars Megnis, Janis Klovins, and Valdis Pirags

Subjects
Adenoma, Adult, Male, 0301 basic medicine, Oncology, Nonsynonymous substitution, medicine.medical_specialty, Genotype, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Pituitary neoplasm, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Proto-Oncogene Proteins, Internal medicine, medicine, GNAS complex locus, Humans, Genetic Predisposition to Disease, Pituitary Neoplasms, education, Genetic Association Studies, Prolactinoma, education.field_of_study, biology, Receptors, Dopamine D2, business.industry, Pituitary tumors, General Medicine, Middle Aged, medicine.disease, 030104 developmental biology, Mutation, biology.protein, Female, business
Abstract

Objective Although pituitary adenomas (PAs) affect a significant proportion of the population, only a fraction have the potential to become clinically relevant during an individual’s lifetime, causing hormonal imbalance or complications due to mass effect. The overwhelming majority of cases are sporadic and without a clear familial history, and the genotype–phenotype correlation in PA patients is poorly understood. Our aim was to investigate the involvement of genes known for their role in familial cases on drug response and tumor suppression in the development and pathology of PAs in a patient group from Latvia. Design The study included 143 cases and 354 controls, we investigated the role of single-nucleotide polymorphisms (SNPs) in seven genes (SSTR2, SSTR5, DRD2, MEN1, AIP, GNAS, and PRKAR1A) associated with pituitary tumor occurrence, phenotype, and clinical symptoms. Methods Genotyping of 96 tag and nonsynonymous SNPs was performed in the genomic regions of interest. Results We discovered a significant association (OR=17.8, CI 0.95=2.18–145.5, P=0.0002) between a rare MEN1 mutation (rs2959656) and clinically active adenoma in our patients. Additionally, rs7131056 at DRD2 was associated with a higher occurrence of extrasellar growth in patients with prolactinoma and somatotropinoma (OR=2.79, CI 0.95=1.58–4.95, P=0.0004). Conclusions rs2959656, a nonsynonymous variant in MEN1, is associated with the development of clinically active PA. Furthermore, rs7131056 in DRD2 contributes to either faster growth of the adenoma or reduced symptomatic presentation, allowing PAs to become larger before detection.

Published
2016
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12. Poster session I * Thursday 9 December 2010, 08:30-12:30

Author

V. A. Kuznetsov, A. O. Kozhurina, A. V. Plusnin, M. Szulik, B. Sredniawa, W. Streb, R. Lenarczyk, J. Stabryla-Deska, A. Sedkowska, O. Kowalski, Z. Kalarus, T. Kukulski, T. M. Katova, A. Nesheva, I. Simova, K. Hristova, V. Kostova, L. Boiadjiev, N. Dimitrov, M. P. Papamichalis Michalis, S. G. Sitafidis George, B. D. Dimopoulos Basilios, G. K. Kelepesis Glafkos, D. E. Economou Dimitrios, J. S. Skoularigis John, F. T. Triposkiadis Filippos, C. H. Attenhofer Jost, M. Pfyffer, B. Naegeli, P. Levis, A. Faeh-Gunz, H. P. Brunner-Larocca, M. S. Velasco Del Castillo, A. Cacicedo, J. J. Onaindia, J. Gonzalez Ruiz, A. Subinas, J. A. Alarcon, O. Quintana, I. Rodriguez, E. Laraudogoitia, Y.-Y. Lam, M. Y. Henein, A. Mazzone, A. Vianello, S. Perlini, A. I. Corciu, S. Cappelli, A. Cerillo, D. Chiappino, S. Berti, M. Glauber, S. Herrmann, M. Niemann, S. Stoerk, J. Strotmann, W. Voelker, G. Ertl, F. Weidemann, Z. Y. Yong, K. Boerlage - Van Dijk, K. T. Koch, M. M. Vis, B. J. Bouma, J. P. S. Henriques, R. Cocchieri, B. A. J. M. De Mol, J. J. Piek, J. Baan, N. G. J. Keenan, C. Cueff, C. Cimadevilla, E. Brochet, L. Lepage, D. Detaint, B. Iung, A. Vahanian, D. Messika-Zeitoun, T. Otsuka, M. Suzuki, H. Yoshikawa, G. Hashimoto, T. Osaki, T. Tsuchida, M. Matsuyama, H. Yamashita, S. Ozaki, K. Sugi, C. J. Garcia Alonso, N. Vallejo Camazon, E. Ferrer Sistach, M. L. Camara, J. Lopez Ayerbe, C. Bosch Carabante, M. Espriu Simon, F. Gual Capllonch, A. Bayes Genis, G. Deswarte, C. Vanesson, A. S. Polge, D. Huchette, T. Modine, P. Marboeuf, N. Lamblin, C. Bauters, G. Deklunder, T. Le Tourneau, A. Agricola, M. Gullace, S. Stella, R. D'amato, M. Slavich, M. Oppizzi, M. Ancona, A. Margonato, F. Le Ven, Y. Etienne, Y. Jobic, I. Frachon, P. Castellant, M. Fatemi, J. J. Blanc, M. Muratori, P. Montorsi, F. Maffessanti, P. Gripari, G. Teruzzi, S. Ghulam Ali, L. Fusini, F. Celeste, M. Pepi, B. Goebel, K. Haugaa, K. Meyer, S. Otto, A. Lauten, C. Jung, T. Edvardsen, H. R. Figulla, T. C. Poerner, H. Aksoy, S. Okutucu, B. Evranos, K. Aytemir, E. B. Kaya, G. Kabakci, L. Tokgozoglu, H. Ozkutlu, A. Oto, N. Valeur, H. H. Pedersen, R. Videbaek, C. Hassager, J. H. Svendsen, L. Kober, M. K. Tigen, T. Karaahmet, E. Gurel, S. Pala, C. Dundar, Y. Basaran, C. I. Caldararu, E. Ene, M. Dorobantu, R. G. Vatasescu, M. Cikes, B. Bijnens, H. Gasparovic, F. Siric, V. Velagic, D. Lovric, J. Samardzic, B. Ferek-Petric, D. Milicic, B. Biocina, J. Kjaergaard, S. Ghio, M. St John Sutton, O. Moreau, G. Kervio, C. Thebault, C. Leclercq, E. Donal, C. Mornos, D. Rusinaru, L. Petrescu, D. Cozma, A. Ionac, S. Pescariu, S. I. Dragulescu, M. Z. Petrovic, B. Vujisic-Tesic, G. Milasinovic, M. T. Petrovic, I. Nedeljkovic, D. Zamaklar-Trifunovic, Z. Calovic, V. Jelic, M. Boricic, I. Petrovic, P. Kuchynka, T. Palecek, S. Simek, E. Nemecek, J. Horak, D. Hulinska, J. Schramlova, I. Vitkova, V. Aster, A. Linhart, L. Paluszkiewicz, D. Guersoy, S. Ozegowski, S. Spiliopoulos, R. Koerfer, G. Tenderich, M. Gaggl, G. Heinze, G. Sunder-Plassmann, S. Graf, M. Zehetmayer, T. Voigtlaender, C. Mannhalter, E. Paschke, G. Fauler, G. Mundigler, M. Tesic, D. Trifunovic, A. Djordjevic-Dikic, O. Petrovic, M. Petrovic, B. Beleslin, M. Ostojic, G. Draganic, C. E. Correia, B. Rodrigues, L. F. Santos, D. Moreira, P. Gama, L. Nunes, C. Nascimento, O. Dionisio, O. Santos, C. Prinz, O. Oldenburg, T. Bitter, C. Piper, D. Horstkotte, L. Faber, A. Nemes, H. Gavaller, M. Csanady, T. Forster, M. Calcagnino, C. O'mahony, K. Tsovolas, P. D. Lambiase, P. Elliott, A. S. Olezac, A. Bensaid, J. Nahum, E. Teiger, J. L. Dubois-Rande, P. Gueret, P. Lim, C. Langer, M. Kansal, P. Surapaneni, P. P. Sengupta, S. J. Lester, S. R. Ommen, S. W. Ressler, R. T. Hurst, V. Monivas Palomero, S. Mingo Santos, C. Mitroi, I. Garcia Lunar, P. Garcia Pavia, J. Gonzalez Mirelis, L. Ruiz Bautista, V. Castro Urda, J. Toquero Ramos, I. Fernandez Lozano, A. Sommer, S. H. Poulsen, J. Mogensen, L. Thuesen, H. Egeblad, R. Montisci, M. Ruscazio, A. Vacca, P. Garau, F. Tuveri, C. Soro, A. Matthieu, L. Meloni, W. Kosmala, M. Przewlocka-Kosmala, A. Wojnalowicz, A. Mysiak, T. H. Marwick, R. Yotti, C. Ripoll, J. Bermejo, Y. Benito, T. Mombiela, D. Rincon, A. Barrio, R. Banares, F. Fernandez-Aviles, A. Tomaszewski, A. Kutarski, M. Tomaszewski, R. Ticulescu, O. Vriz, L. Sparacino, B. A. Popescu, C. Ginghina, G. L. Nicolosi, S. Carerj, F. Antonini-Canterin, E. Agricola, L. Bertoglio, G. Melissano, R. Chiesa, S. Garcia Blas, D. Iglesias Del Valle, T. Lopez Fernandez, J. J. Gomez De Diego, M. C. Monedero Martin, F. J. Dominguez, M. Moreno Yanguela, J. L. Lopez Sendon, S. Adhya, F. D. Murgatroyd, M. Monaghan, L. Spinarova, J. Meluzin, P. Hude, J. Krejci, H. Podrouzkova, M. Pesl, R. Panovsky, L. Dusek, M. Orban, J. Korinek, C. Hammerstingl, M. Schwiekendik, G. Nickenig, D. Momcilovic, L. Lickfett, C. C. Beladan, A. Calin, M. Rosca, D. Muraru, F. Voinea, E. Popa, F. Matei, F. Curea, G. Di Salvo, G. Pacileo, S. Gala, B. Castaldi, A. F. D'aiello, A. Mormile, L. Baldini, M. G. Russo, R. Calabro, P. S. Halvorsen, G. Dahle, J. F. Bugge, B. Bendz, L. Aaberge, K. A. Rein, A. Fiane, J. Bergsland, E. Fosse, S. Aakhus, L. P. Koopman, N. Chahal, C. Slorach, W. Hui, T. Sarkola, C. Manlhiot, T. J. Bradley, E. T. Jaeggi, B. W. Mccrindle, L. Mertens, F. A. D'aiello, A. Mormilw, A. Rea, K. O'Connor, G. Romano, J. Magne, L. Pierard, P. Lancellotti, T. Arita, K. Ando, A. Isotani, Y. Soga, M. Iwabuchi, M. Nobuyoshi, M. Wiesen, D. Skowasch, F. Breunig, M. Beer, K. Hu, C. Wanner, M. A. Morel, Y. F. Bernard, V. Descotes-Genon, N. Meneveau, F. Schiele, A. Vitarelli, M. Bernardi, A. Scarno, F. Caranci, V. Padella, O. Dettori, L. Capotosto, M. Vitarelli, V. De Cicco, P. Bruno, G. Bajraktari, P. Lindqvist, U. Gustafsson, A. Holmgren, M. Hassan, K. Said, E. Baligh, H. Farouk, D. Osama, M. F. Elmahdy, A. Elfaramawy, K. Sorour, M. Luckie, A. Zaidi, A. Fitzpatrick, R. S. Khattar, J. Schwartz, O. Huttin, B. Popovic, P. Y. Zinzius, C. Christophe, O. Marcon, L. Groben, Y. Juilliere, F. Chabot, C. Selton-Suty, B. Krastev, E. T. K. Kinova, N. I. Z. Zlatareva, A. R. G. Goudev, A. J. Teske, B. W. De Boeck, F. A. Mohames Hoesein, V. Van Driel, P. Loh, M. J. Cramer, P. A. Doevendans, F. Dillenburg, K. M. Abd El Salam, E. M. M. Ho, M. Hall, L. Hemeryck, K. Bennett, K. Scott, G. King, R. T. Murphy, A. Mahmud, A. S. Brown, H. Dalen, A. Thorstensen, P. R. Romundstad, S. A. Aase, A. Stoylen, L. Vatten, T. Bochenek, K. Wita, Z. Tabor, A. Doruchowska, M. Lelek, M. Trusz-Gluza, E. Hamodraka, I. Paraskevaidis, A. Karamanou, C. Michalakeas, H. Vrettou, E. Kapsali, D. Tsiapras, I. Lekakis, M. Anastasiou-Nana, D. Kremastinos, L. Sirugo, V. E. Bottari, S. Licciardi, A. Blundo, A. Atanasio, I. P. Monte, C. S. Park, J. H. Kim, J. S. Cho, M. J. Kim, E. J. Cho, S. H. Ihm, H. O. Jung, H. K. Jeon, H. J. Youn, K. S. Kim, A. Fontana, L. Taravella, A. Zambon, G. Trocino, C. Giannattasio, A. Kalinin, M. Alekhin, G. Bahs, A. Lejnieks, A. Kalvelis, A. Kalnins, P. Shipachovs, E. Zakharova, G. Blumentale, M. Trukshina, T. Biering-Sorensen, R. Mogelvang, S. Haahr-Pedersen, P. Schnohr, P. Sogaard, J. Skov Jensen, L. Gargani, G. Agoston, E. Capati, L. Badano, A. Moreo, M. F. Costantino, M. L. Caputo, S. Mondillo, R. Sicari, E. Picano, E. G. Malev, E. V. Timofeev, S. V. Reeva, E. V. Zemtsovsky, R. Piazza, R. Enache, A. Roman-Pognuz, E. Leiballi, R. Pecoraro, H. Sadeghian, M. Lotfi_Tokaldany, M. Rezvanfard, A. Kasemisaeid, S. Majidi, M. Montazeri, M. Saber-Ayad, Y. S. Nassar, A. Farhan, A. Moussa, A. El-Sherif, R. M. Cooper, J. D. Somauroo, R. E. Shave, K. L. Williams, J. Forster, C. George, T. Bett, D. C. Gaze, K. P. George, N. Mansencal, A. Dupland, V. Caille, S. Perrot, K. Bouferrache, A. Vieillard-Baron, R. Jouffroy, S. G. Cioroiu, O. S. Alexe, E. Bobescu, H. Rus, V. Schiano Lomoriello, R. Esposito, A. Santoro, R. Raia, F. Farina, R. Ippolito, M. Galderisi, E. H. Aburawi, P. Malcus, A. Thuring, A. Maxedius, E. Pesonen, S. V. Nair, E. Joyce, L. Lee, J. Shrimpton, E. Newman, P. R. James, C. Jurcut, S. Caraiola, R. O. Jurcut, S. Giusca, D. Nitescu, M. S. Amzulescu, I. Copaci, C. Tanasescu, J. Silva Marques, D. Silva, F. Ferreira, P. C. Ferreira, A. G. Almeida, J. Martim Martins, M. G. Lopes, L. Bergenzaun, M. Chew, A. Ersson, P. Gudmundsson, H. Ohlin, A. Borowiec, R. Dabrowski, J. Wozniak, S. Jasek, T. Chwyczko, I. Kowalik, E. Musiej-Nowakowska, H. Szwed, Y. L. Wen, J. Tian, L. Yan, H. Cheng, H. Yang, B. Luo, J. Wang, H. Kozman, D. Villarreal, K. Liu, A. Karavidas, D. Tsiachris, G. Lazaros, V. Matzaraki, G. Xylomenos, G. Levendopoulos, S. Arapi, A. Perpinia, E. Matsakas, V. Pyrgakis, Y. W. Liu, C. T. Su, W. C. Tsai, J. W. Huang, K. Y. Hung, J. H. Chen, M. Larsson, F. Kremer, T. Kouznetsova, A. Bjallmark, B. Lind, L.-A. Brodin, J. D'hooge, M. Caputo, G. Antonelli, M. Lisi, E. Giacomin, S. Moustafa, M. Alharthi, Y. Deng, K. Chandrasekaran, F. Mookadam, S. Y. Hayashi, M. M. Nascimento, B. Lindholm, A. Seeberger, J. Nowak, M. C. Riella, L. A. Brodin, A. Theodosis, E. Fousteris, G. Tsiaousis, A. Krommydas, P. Margetis, Z. Katidis, D. Beldekos, S. Argirakis, A. Melidonis, S. Foussas, O. Khaleva, O. Onyshchenko, E. Lukaschuk, N. Sherwi, N. Nikitin, J. G. F. Cleland, N. Risum, C. Jons, N. T. Olsen, M. B. Kronborg, M. T. Jensen, T. Fritz-Hansen, N. E. Bruun, M. V. Hojgaard, J. Petrini, M. Yousry, A. Rickenlund, J. Liska, A. Franco-Cereceda, A. Hamsten, P. Eriksson, K. Caidahl, M. J. Eriksson, N. Elmstedt, K. Ferm-Widlund, M. Westgren, E. Szymczyk, J. D. Kasprzak, B. Wozniakowski, A. Rotkiewicz, K. Szymczyk, L. Stefanczyk, B. Michalski, P. Lipiec, L. Ring, T. Eller, P. Deegan, R. Rusk, J. A. Urbano Moral, J. A. Arias, J. T. Kuvin, A. R. Patel, N. G. Pandian, H. Bellsham-Revell, A. J. Bell, O. Miller, G. F. Greil, J. Simpson, R. Ancona, S. Comenale Pinto, P. Caso, S. Severino, L. Nunziata, T. Roselli, C. Dussault, S. Lafitte, G. Habib, P. Reant, G. Derumeaux, H. Thibault, A. Kaladaridis, I. A. Agrios, C. P. Pamboucas, S. M. Mesogitis, N. V. Vasiladiotis, D. B. Bramos, S. T. T. Toumanidis, A. R. Martiniello, G. Santangelo, G. Pedrizzetti, G. Tonti, C. Cioppa, M. Cavallaro, V. Calvi, and R. Chianese

Subjects
Speckle pattern, Longitudinal strain, business.industry, Carotid arteries, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine, business, Tracking (particle physics), Biomedical engineering
Abstract

Radial and longitudinal strain assessment in the carotid artery wall using speckle tracking

Published
2010
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13. P391Potential drug interactions with oral anticoagulants among atrial fibrillation patients

Author

K Pukite, N Nikrus, A Tupahins, K. Apsite, Aivars Lejnieks, Irina Pupkevica, Oskars Kalejs, and Baiba Lurina

Subjects
Drug, medicine.medical_specialty, business.industry, Physiology (medical), Internal medicine, media_common.quotation_subject, medicine, Cardiology, Atrial fibrillation, Cardiology and Cardiovascular Medicine, medicine.disease, business, media_common
Published
2018
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14. P383Health related quality of life depending on oral anticoagulant type among high-risk atrial fibrillation patients

Author

Voicehovskis, T Ivascenko, Baiba Lurina, Oskars Kalejs, A Tupahins, K. Apsite, and Aivars Lejnieks

Subjects
medicine.medical_specialty, Quality of life, business.industry, Physiology (medical), Internal medicine, Oral anticoagulant, Medicine, Atrial fibrillation, Cardiology and Cardiovascular Medicine, business, medicine.disease
Published
2018
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17. Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients

Author

Zaharenko, Linda, primary, Kalnina, Ineta, additional, Geldnere, Kristine, additional, Konrade, Ilze, additional, Grinberga, Solveiga, additional, Židzik, Jozef, additional, Javorský, Martin, additional, Lejnieks, Aivars, additional, Nikitina-Zake, Liene, additional, Fridmanis, Davids, additional, Peculis, Raitis, additional, Radovica-Spalvina, Ilze, additional, Hartmane, Dace, additional, Pugovics, Osvalds, additional, Tkáč, Ivan, additional, Klimčáková, Lucia, additional, Pīrāgs, Valdis, additional, and Klovins, Janis, additional

Published
2016
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18. 136-83: Results of monitoring large artery cryptogenic embolic stroke survivors using implantable loop recorder device

Author

Kalejs, Oskars, primary, Jurjans, Kristaps, additional, Jubele, Kristine, additional, Kamzola, Ginta, additional, Nikrus, Natālija, additional, Nesterovics, Nikolajs, additional, Blumbergs, Maris, additional, Lavrinovics, Arnolds, additional, Lurina, Baiba, additional, Miglane, Evija, additional, and Lejnieks, Aivars, additional

Published
2016
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20. 153-05: Comparison of rivaroxaban, dabigatran and warfarin in patients with high risk of stroke and embolism undergoing electrical cardioversion with persistent and long-standing atrial fibrillation

Author

Kalejs, Oskars, primary, Aldis, Strelnieks, additional, Jubele, Kristine, additional, Iveta, Sime, additional, Irina, Sproge, additional, Ginta, Kamzola, additional, Marina, Berzina, additional, Sakne, Sandis, additional, Maija, Vikmane, additional, Marina, Kovalova, additional, Lejnieks, Aivars, additional, and Andrejs, Erglis, additional

Published
2016
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21. P783 Ciprofloxacin resistance in ESBL producing enterobacteriaceae colonizing the gut in IBD patients

Author

K. Pekarska, H. Dauvarte, L. Piekuse, P. Zalizko, A. Lejnieks, Z. Straume, V. Skuja, A. Derovs, E. Lavrinoviča, A. Krūmiņa, E. Vašuka, D. Rudzīte, and L. Dobelniece

Subjects
biology, medicine.drug_class, business.industry, Antibiotics, Gastroenterology, Klebsiella oxytoca, General Medicine, biology.organism_classification, medicine.disease, Ulcerative colitis, Enterobacteriaceae, Microbiology, Ciprofloxacin, Ciprofloxacin resistance, Escherichia, medicine, business, Bacteria, medicine.drug
Published
2017
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22. 136-83: Results of monitoring large artery cryptogenic embolic stroke survivors using implantable loop recorder device

Author

Natālija Nikrus, Ginta Kamzola, Maris Blumbergs, Kristaps Jurjans, Aivars Lejnieks, Kristine Jubele, Arnolds Lavrinovics, Nikolajs Nesterovics, Oskars Kalejs, Evija Miglane, and Baiba Lurina

Subjects
Secondary prevention, medicine.medical_specialty, Cerebral infarction, business.industry, Large artery, medicine.disease, Embolic stroke, Computed tomographic angiography, Embolism, Physiology (medical), Internal medicine, medicine, Cardiology, Implantable loop recorder, Cardiology and Cardiovascular Medicine, business, Fibrinolytic agent
Published
2016
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23. 153-05: Comparison of rivaroxaban, dabigatran and warfarin in patients with high risk of stroke and embolism undergoing electrical cardioversion with persistent and long-standing atrial fibrillation

Author

Vikmane Maija, Erglis Andrejs, Strelnieks Aldis, Berzina Marina, Kristine Jubele, Aivars Lejnieks, Sandis Sakne, Sproge Irina, Sime Iveta, Kovalova Marina, Kamzola Ginta, and Oskars Kalejs

Subjects
Rivaroxaban, medicine.medical_specialty, business.industry, Warfarin, Atrial fibrillation, medicine.disease, Dabigatran, Electrical cardioversion, Embolism, Physiology (medical), Internal medicine, Cardiology, Medicine, In patient, Cardiology and Cardiovascular Medicine, business, Stroke, medicine.drug
Published
2016
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24. Poster Session 2

Author

Andersson, T., primary, Magnusson, A., additional, Bryngelsson, I.- L., additional, Frobert, O., additional, Henriksson, K. M., additional, Edvardsson, N., additional, Poci, D., additional, Polovina, M., additional, Potpara, T., additional, Licina, M., additional, Mujovic, N., additional, Kocijancic, A., additional, Simic, D., additional, Ostojic, M. C., additional, Providencia, R. A., additional, Botelho, A., additional, Trigo, J., additional, Nascimento, J., additional, Quintal, N., additional, Mota, P., additional, Leitao-Marques, A. M., additional, Bosch, R. F., additional, Kirch, W., additional, Rosin, L., additional, Willich, S. N., additional, Pittrow, D., additional, Bonnemeier, H., additional, Valenza, M. C., additional, Martin, L., additional, Munoz Casaubon, T., additional, Valenza, G., additional, Botella, M., additional, Serrano, M., additional, Valenza, B., additional, Cabrera, I., additional, Anderson, K., additional, Benzaquen, B. S., additional, Koziolova, N., additional, Nikonova, J., additional, Shilova, Y., additional, Scherr, D., additional, Narayan, S., additional, Wright, M., additional, Krummen, D., additional, Jadidi, A., additional, Jais, P., additional, Haissaguerre, M., additional, Hocini, M., additional, Hunter, R., additional, Liu, Y., additional, Lu, Y., additional, Wang, W., additional, Schilling, R. J., additional, Bernstein, S., additional, Wong, B., additional, Rooke, R., additional, Vasquez, C., additional, Shah, R., additional, Rosenberg, S., additional, Chinitz, L., additional, Morley, G., additional, Bashir Choudhary, M., additional, Holmqvist, F., additional, Carlson, J., additional, Nilsson, H.- J., additional, Platonov, P. G., additional, Jadidi, A. S., additional, Cochet, H., additional, Miyazaki, S., additional, Shah, A. J., additional, Marrouche, N., additional, Calvo, N., additional, Nadal, M., additional, Andreu, D., additional, Tamborero, D., additional, Diaz, F. E., additional, Berruezo, A., additional, Brugada, J., additional, Mont, L., additional, Fichtner, S., additional, Hessling, G., additional, Estner, H. L., additional, Jilek, C., additional, Reents, T., additional, Ammar, S., additional, Wu, J., additional, Deisenhofer, I., additional, Nakanishi, H., additional, Kashiwase, K., additional, Hirata, A., additional, Wada, M., additional, Ueda, Y., additional, Skoda, J., additional, Neuzil, P., additional, Popelova, J., additional, Petru, J., additional, Sediva, L., additional, Reddy, V. Y., additional, Uldry, L., additional, Forclaz, A., additional, Virag, N., additional, Vesin, J.- M., additional, Kappenberger, L., additional, Sehra, R., additional, Briggs, C., additional, Rappel, W.- J., additional, Janotka, M., additional, Chovanec, M., additional, Yamashiro, K., additional, Takami, K., additional, Sakamoto, Y., additional, Satoh, K., additional, Suzuki, T., additional, Nakagawa, H., additional, Romanov, A., additional, Pokushalov, E., additional, Artemenko, S., additional, Shabanov, V., additional, Stenin, I., additional, Elesin, D., additional, Turov, A., additional, Yakubov, A., additional, Hioki, M., additional, Matsuo, S., additional, Ito, K., additional, Narui, R., additional, Yamashita, S., additional, Sugimoto, K., additional, Yoshimura, M., additional, Yamane, T., additional, Di Biase, L., additional, Gallinghouse, J. D., additional, Rajappan, K., additional, Kautzner, J., additional, Dello Russo, A., additional, Tondo, C., additional, Lorgat, F., additional, Natale, A., additional, Balta, O., additional, Buenz, K., additional, Paessler, M., additional, Anders, H., additional, Horlitz, M., additional, Deneke, T., additional, Lickfett, L., additional, Liberman, I., additional, Linhart, M., additional, Andrie, R., additional, Mittmann-Braun, E., additional, Stockigt, F., additional, Nickenig, G., additional, Schrickel, J., additional, Tilz, R., additional, Rillig, A., additional, Feige, B., additional, Metzner, A., additional, Fuernkranz, A., additional, Burchard, A., additional, Wissner, E., additional, Ouyang, F., additional, Betts, T. R., additional, Jones, M. A., additional, Wong, K. C. K., additional, Qureshi, N., additional, Bashir, Y., additional, Corbucci, G., additional, Losik, D., additional, Selina, V., additional, Crandall, M. A., additional, Daniels, C., additional, Daoud, E., additional, Kalbfleisch, S., additional, Yamaji, H., additional, Murakami, T., additional, Kawamura, H., additional, Murakami, M., additional, Hina, K., additional, Kusachi, S., additional, Dakos, G., additional, Vassilikos, V., additional, Paraskevaidis, S., additional, Mantziari, A., additional, Theophylogiannakos, S., additional, Chouvarda, I., additional, Chatzizisis, I., additional, Styliadis, I., additional, Kimura, T., additional, Fukumoto, K., additional, Nishiyama, N., additional, Aizawa, Y., additional, Fukuda, Y., additional, Sato, T., additional, Miyoshi, S., additional, Takatsuki, S., additional, Navarrete Casas, A. J., additional, Ali, I., additional, Conte, F. C., additional, Moran, M., additional, Graham, B. G., additional, Kalejs, O., additional, Lacis, R., additional, Stradins, P., additional, Koris, A., additional, Putnins, I., additional, Vikmane, M., additional, Lejnieks, A., additional, Erglis, A., additional, Estrada, A., additional, Perez Silva, A., additional, Castrejon, S., additional, Doiny, D., additional, Merino, J. L., additional, Baranchuk, A., additional, Greiss, I., additional, Simpson, C. S., additional, Abdollah, H., additional, Redfearn, D. P., additional, Buys-Topart, M., additional, Nitzsche, R., additional, Thibault, B., additional, Kathan, S., additional, Kolb, C., additional, Reif, S., additional, Schade, S., additional, Taggeselle, J., additional, Frey, A., additional, Birkenhagen, A., additional, Kohler, S., additional, Schmidt, M., additional, Cano Perez, O., additional, Buendia, F., additional, Igual, B., additional, Osca, J. M., additional, Sanchez, J. M., additional, Sancho-Tello, M. J., additional, Olague, J. M., additional, Salvador, A., additional, Tolosana, J. M., additional, Fernandez-Armenta, J., additional, Matas, M., additional, Barbarin, M. C., additional, Habibovic, M., additional, Van Den Broek, K. C., additional, Theuns, D. A. M. J., additional, Jordaens, L., additional, Alings, M., additional, Van Der Voort, P. H., additional, Pedersen, S. S., additional, Pupita, G., additional, Molini, S., additional, Brambatti, M., additional, Capucci, A., additional, Molodykh, S., additional, Idov, E. M., additional, Belyaev, O. V., additional, Segreti, L., additional, Soldati, E., additional, Zucchelli, G., additional, Di Cori, A., additional, Viani, S., additional, Paperini, L., additional, De Lucia, R., additional, Bongiorni, M. G., additional, Binner, L., additional, Taborsky, M., additional, Bello, D., additional, Heuer, H., additional, Ramza, B., additional, Jenniskens, I., additional, Johnson, W. B., additional, Silvetti, M. S., additional, Rava', L., additional, Russo, M. S., additional, Di Mambro, C., additional, Ammirati, A., additional, Gimigliano, G., additional, Prosperi, M., additional, Drago, F., additional, Santos, A. R., additional, Picarra, B., additional, Semedo, P., additional, Dionisio, P., additional, Matos, R., additional, Leitao, M., additional, Jacinto, A., additional, Trinca, M., additional, Mazzone, P., additional, Ciconte, G., additional, Marzi, A., additional, Paglino, G., additional, Vergara, P., additional, Sora, N., additional, Gulletta, S., additional, Della Bella, P., additional, Koppitz, P., additional, Fach, A., additional, Hobbiesiefken, S., additional, Fiehn, E., additional, Hambrecht, R., additional, Sperzel, J., additional, Jung, M., additional, Schmitt, J., additional, Pajitnev, D., additional, Burger, H., additional, Goebel, G., additional, Ehrlich, W., additional, Walther, T., additional, Ziegelhoeffer, T., additional, Vancura, V., additional, Wichterle, D., additional, Melenovsky, V., additional, Glikson, M., additional, Goldenberg, G., additional, Segev, A., additional, Dvir, D., additional, Kuzniec, J., additional, Finkelstein, A., additional, Hay, I., additional, Guetta, V., additional, Choo, W. K., additional, Gupta, S., additional, Kirkfeldt, R., additional, Johansen, J., additional, Nohr, E., additional, Moller, M., additional, Arnsbo, P., additional, Nielsen, J., additional, Banha, M., additional, Stojanov, P., additional, Raspopovic, S., additional, Vasic, D., additional, Savic, D., additional, Nikcevic, G., additional, Jovanovic, V., additional, Defaye, P., additional, Mondesert, B., additional, Mbaye, A., additional, Cassagneau, R., additional, Gagniere, V., additional, Jacon, J., additional, Sanfins, V., additional, Reis, H. R., additional, Nobre, J. N., additional, Martins, V. M., additional, Duarte, L. D., additional, Morais, C. M., additional, Conceicao, J. C., additional, Hero, M., additional, Rey, J. L., additional, Ducharme, A., additional, Simpson, C., additional, Stuglin, C., additional, Blier, L., additional, Senaratne, M., additional, Khaykin, Y., additional, Pinter, A., additional, Mlynarska, A., additional, Mlynarski, R., additional, Sosnowski, M., additional, Wilczek, J., additional, Iorgulescu, C., additional, Bogdan, S., additional, Constantinescu, D., additional, Caldararu, C., additional, Dorobantu, M., additional, Radu, A., additional, Vatasescu, R.- G., additional, Yusu, S., additional, Ikeda, T., additional, Mera, H., additional, Miwa, Y., additional, Abe, A., additional, Miyakoshi, M., additional, Tsukada, T., additional, Yoshino, H., additional, Nayar, V., additional, Cantelon, P., additional, Rawling, A., additional, Belham, M. R. D., additional, Pugh, P. J., additional, Osca Asensi, J., additional, Cano, O., additional, Tejada, D., additional, Munoz, B., additional, Rodriguez, M., additional, Olague, J., additional, Wecke, L., additional, Van Hunnik, A., additional, Thompson, T., additional, Di Carlo, L., additional, Zdeblick, M., additional, Auricchio, A., additional, Prinzen, F., additional, Doltra Magarolas, A., additional, Bijnens, B., additional, Silva, E., additional, Penela, D., additional, Sitges, M., additional, Ofman, P., additional, Navaravong, L., additional, Leng, J., additional, Peralta, A., additional, Hoffmeister, P., additional, Levine, R., additional, Cook, J., additional, Stoenescu, M., additional, Tettamanti, M. E., additional, Revilla Orodea, A., additional, Lopez Diaz, J., additional, De La Fuente Galan, L., additional, Arnold, R., additional, Garcia Moran, E., additional, San Roman Calvar, J. A., additional, Gomez Salvador, I., additional, Nakamura, K., additional, Takami, M., additional, Keida, T., additional, Mesato, A., additional, Higa, S., additional, Shimabukuro, M., additional, Masuzaki, H., additional, Proietti, R., additional, Sagone, A., additional, Domenichini, G., additional, Burri, H., additional, Valzania, C., additional, Biffi, M., additional, Sunthorn, H., additional, Gavaruzzi, G., additional, Foulkes, H., additional, Boriani, G., additional, Koh, S., additional, Hou, W., additional, Snell, J., additional, Poore, J., additional, Dalal, N., additional, Bornzin, G., additional, Kloppe, A., additional, Mijic, D., additional, Bogossian, H., additional, Ninios, I., additional, Zarse, M., additional, Lemke, B., additional, Guedon-Moreau, L., additional, Kouakam, C., additional, Klug, D., additional, Marquie, C., additional, Ziglio, F., additional, Kacet, S., additional, Mohamed Fereig Hamed, H., additional, Hamdy, A. M. A. L., additional, Abd El Aziz, A. H. M. E. D., additional, Nabih, M. R. V. A. T., additional, Hamdy, R. E. H. A. B., additional, Yaminisaharif, A., additional, Davoudi, G. H., additional, Kasemisaeid, A., additional, Sadeghian, S., additional, Vasheghani Farahani, A., additional, Yazdanifard, P., additional, Shafiee, A., additional, Alonso, C., additional, Grimard, C., additional, Jauvert, G., additional, Lazarus, A., additional, Mont, L. L., additional, Ortiz-Perez, J., additional, Caralt, T., additional, Escudero, J., additional, Perez, F., additional, Griffith, K. M., additional, Ferreyra, R., additional, Urena, P., additional, Demas, M., additional, Muratore, C., additional, Mazzetti, H., additional, Guardado, J., additional, Fernandes, M., additional, Pereira, V. H., additional, Canario-Almeida, F., additional, Ferreira, F., additional, Rodrigues, B., additional, Almeida, J., additional, Sokal, A., additional, Jedrzejczyk, E., additional, Lenarczyk, R., additional, Pluta, S., additional, Kowalski, O., additional, Pruszkowska, P., additional, Swiatkowski, A., additional, Kalarus, Z., additional, Heinke, M., additional, Ismer, B., additional, Kuehnert, H., additional, Heinke, T., additional, Surber, R., additional, Osypka, N., additional, Prochnau, D., additional, Figulla, H. R., additional, Iacopino, S., additional, Landolina, M., additional, Proclemer, A., additional, Padeletti, L., additional, Calvi, V., additional, Pierantozzi, A., additional, Di Stefano, P., additional, Bauer, A., additional, Bode, F., additional, Le Gal, F., additional, Deharo, J. C., additional, Delay, M., additional, Clementy, J., additional, Kawamura, M., additional, Munetsugu, Y., additional, Tanno, K., additional, Kobayashi, Y., additional, Cannom, D., additional, Hosoda, J., additional, Ishikawa, T., additional, Andoh, K., additional, Nobuyoshi, M., additional, Fujii, S., additional, Shizuta, S., additional, Isshiki, T., additional, Castel, M. A., additional, Perez-Villa, F., additional, Vidal, B., additional, Pruszkowska-Skrzep, P., additional, Szulik, M., additional, Kukulski, T., additional, Gianfranchi, L., additional, Bettiol, K., additional, Pacchioni, F., additional, Alboni, P., additional, Abu Sham'a, R., additional, Buber, J., additional, Nof, E., additional, Kuperstein, R., additional, Feinberg, M., additional, Luria, D., additional, Eldar, M., additional, Parks, K., additional, Stone, J. R., additional, Singh, J. P., additional, Hatzinikolaou-Kotsakou, E., additional, Kotsakou, M., additional, Beleveslis, T. H., additional, Moschos, G., additional, Reppas, E., additional, Latsios, P., additional, Tsakiridis, K., additional, Kazemisaeid, A., additional, Davoodi, G., additional, Yamini Sharif, A., additional, Sheikhvatan, M., additional, Toniolo, M., additional, Zanotto, G., additional, Rossi, A., additional, Tomasi, L., additional, Vassanelli, C., additional, Versteeg, H., additional, Mommersteeg, P. M. C., additional, Vergara, G., additional, Blauer, J., additional, Ranjan, R., additional, Vijayakumar, S., additional, Kholmovski, E., additional, Volland, N., additional, Macleod, R., additional, Aguinaga Arrascue, L. E., additional, Bravo, A., additional, Garcia Freire, P., additional, Gallardo, P., additional, Hasbani, E., additional, Dantur, J., additional, Quintana, R., additional, Adragao, P. P., additional, Cavaco, D., additional, Parreira, L., additional, Reis Santos, K., additional, Carmo, P., additional, Miranda, R., additional, Marcelino, S., additional, Cabrita, D., additional, Sommer, P., additional, Gaspar, T., additional, Rolf, S., additional, Arya, A., additional, Piorkowski, C., additional, Hindricks, G., additional, Valles Gras, E., additional, Bazan, V., additional, Portillo, L., additional, Suarez, F., additional, Bruguera, J., additional, Marti, J., additional, Huo, Y., additional, Richter, S., additional, Schoenbauer, R., additional, Rivas, N., additional, Casaldaliga, J., additional, Roca, I., additional, Dos, L., additional, Perez-Rodon, J., additional, Pijuan, A., additional, Garcia-Dorado, D., additional, Moya, A., additional, Carter, H. B., additional, Garg, A., additional, Hegrenes, J., additional, Sih, H. J., additional, Teplitsky, L. R., additional, Kuroki, K., additional, Tada, H., additional, Seo, Y., additional, Ishizu, T., additional, Igawa, M., additional, Sekiguchi, Y., additional, Kuga, K., additional, Aonuma, K., additional, Rodriguez A, C., additional, Mejias, J., additional, Hidalgo, P., additional, Hidalgo L, J. A., additional, Orczykowski, M., additional, Derejko, P., additional, Walczak, F., additional, Szufladowicz, E., additional, Urbanek, P., additional, Bodalski, R., additional, Bieganowska, K., additional, Szumowski, L., additional, Peichl, P., additional, Cihak, R., additional, Skalsky, I., additional, Kubus, P., additional, Vit, P., additional, Zaoral, L., additional, Gebauer, R. A., additional, Fiala, M., additional, Janousek, J., additional, Hiroshima, K., additional, Goya, M., additional, Ohe, M., additional, Hayashi, K., additional, Makihara, Y., additional, Nagashima, M., additional, An, Y., additional, Schloesser, M., additional, Lawrenz, T., additional, Meyer Zu Vilsendorf, D., additional, Strunk-Mueller, C., additional, Stellbrink, C., additional, Papagiannis, J., additional, Avramidis, D., additional, Kokkinakis, C., additional, Kirvassilis, G., additional, Eidelman, G., additional, Arenal, A., additional, Datino, T., additional, Atienza, F., additional, Gonzalez Torrecilla, E., additional, Miracle, A., additional, Hernandez, J., additional, Fernandez Aviles, F., additional, Ene, E., additional, Insulander, P., additional, Bastani, H., additional, Braunschweig, F., additional, Drca, N., additional, Kenneback, G., additional, Schwieler, J., additional, Tapanainen, J., additional, Jensen-Urstad, M., additional, Andrea, B., additional, Andrea, E. M. 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M., additional, Daba, L., additional, Liebrecht, K., additional, Piwowarska, W., additional, Toquero Ramos, J., additional, Perez Pereira, E., additional, Mitroi, C., additional, Castro Urda, V., additional, Fernandez Villanueva, J. M., additional, Corona Figueroa, A., additional, Hernandez Reina, L., additional, Fernandez Lozano, I., additional, Bartoletti, A., additional, Bocconcelli, P., additional, Giuli, S., additional, Massa, R., additional, Svetlich, C., additional, Tarsi, G., additional, Tronconi, F., additional, Vitale, E., additional, Stryjewski, P., additional, Wegrzynowska, M., additional, Lousinha, A., additional, Labandeiro, J., additional, Antunes, E., additional, Silva, S., additional, Alves, S., additional, Timoteo, A., additional, Oliveira, M., additional, Cruz Ferreira, R., additional, and Jedrzejczyk-Spaho, J., additional

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2011
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25. Poster session I * Thursday 9 December 2010, 08:30-12:30

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Kuznetsov, V. A., primary, Kozhurina, A. O., additional, Plusnin, A. V., additional, Szulik, M., additional, Sredniawa, B., additional, Streb, W., additional, Lenarczyk, R., additional, Stabryla-Deska, J., additional, Sedkowska, A., additional, Kowalski, O., additional, Kalarus, Z., additional, Kukulski, T., additional, Katova, T. M., additional, Nesheva, A., additional, Simova, I., additional, Hristova, K., additional, Kostova, V., additional, Boiadjiev, L., additional, Dimitrov, N., additional, Papamichalis Michalis, M. P., additional, Sitafidis George, S. G., additional, Dimopoulos Basilios, B. D., additional, Kelepesis Glafkos, G. K., additional, Economou Dimitrios, D. E., additional, Skoularigis John, J. S., additional, Triposkiadis Filippos, F. T., additional, Attenhofer Jost, C. H., additional, Pfyffer, M., additional, Naegeli, B., additional, Levis, P., additional, Faeh-Gunz, A., additional, Brunner-Larocca, H. P., additional, Velasco Del Castillo, M. S., additional, Cacicedo, A., additional, Onaindia, J. J., additional, Gonzalez Ruiz, J., additional, Subinas, A., additional, Alarcon, J. A., additional, Quintana, O., additional, Rodriguez, I., additional, Laraudogoitia, E., additional, Lam, Y.-Y., additional, Henein, M. Y., additional, Mazzone, A., additional, Vianello, A., additional, Perlini, S., additional, Corciu, A. I., additional, Cappelli, S., additional, Cerillo, A., additional, Chiappino, D., additional, Berti, S., additional, Glauber, M., additional, Herrmann, S., additional, Niemann, M., additional, Stoerk, S., additional, Strotmann, J., additional, Voelker, W., additional, Ertl, G., additional, Weidemann, F., additional, Yong, Z. Y., additional, Boerlage - Van Dijk, K., additional, Koch, K. T., additional, Vis, M. M., additional, Bouma, B. J., additional, Henriques, J. P. S., additional, Cocchieri, R., additional, De Mol, B. A. J. M., additional, Piek, J. J., additional, Baan, J., additional, Keenan, N. G. J., additional, Cueff, C., additional, Cimadevilla, C., additional, Brochet, E., additional, Lepage, L., additional, Detaint, D., additional, Iung, B., additional, Vahanian, A., additional, Messika-Zeitoun, D., additional, Otsuka, T., additional, Suzuki, M., additional, Yoshikawa, H., additional, Hashimoto, G., additional, Osaki, T., additional, Tsuchida, T., additional, Matsuyama, M., additional, Yamashita, H., additional, Ozaki, S., additional, Sugi, K., additional, Garcia Alonso, C. J., additional, Vallejo Camazon, N., additional, Ferrer Sistach, E., additional, Camara, M. L., additional, Lopez Ayerbe, J., additional, Bosch Carabante, C., additional, Espriu Simon, M., additional, Gual Capllonch, F., additional, Bayes Genis, A., additional, Deswarte, G., additional, Vanesson, C., additional, Polge, A. 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G., additional, Bergenzaun, L., additional, Chew, M., additional, Ersson, A., additional, Gudmundsson, P., additional, Ohlin, H., additional, Borowiec, A., additional, Dabrowski, R., additional, Wozniak, J., additional, Jasek, S., additional, Chwyczko, T., additional, Kowalik, I., additional, Musiej-Nowakowska, E., additional, Szwed, H., additional, Wen, Y. L., additional, Tian, J., additional, Yan, L., additional, Cheng, H., additional, Yang, H., additional, Luo, B., additional, Wang, J., additional, Kozman, H., additional, Villarreal, D., additional, Liu, K., additional, Karavidas, A., additional, Tsiachris, D., additional, Lazaros, G., additional, Matzaraki, V., additional, Xylomenos, G., additional, Levendopoulos, G., additional, Arapi, S., additional, Perpinia, A., additional, Matsakas, E., additional, Pyrgakis, V., additional, Liu, Y. W., additional, Su, C. T., additional, Tsai, W. C., additional, Huang, J. W., additional, Hung, K. Y., additional, Chen, J. H., additional, Larsson, M., additional, Kremer, F., additional, Kouznetsova, T., additional, Bjallmark, A., additional, Lind, B., additional, Brodin, L.-A., additional, D'hooge, J., additional, Caputo, M., additional, Antonelli, G., additional, Lisi, M., additional, Giacomin, E., additional, Moustafa, S., additional, Alharthi, M., additional, Deng, Y., additional, Chandrasekaran, K., additional, Mookadam, F., additional, Hayashi, S. Y., additional, Nascimento, M. M., additional, Lindholm, B., additional, Seeberger, A., additional, Nowak, J., additional, Riella, M. C., additional, Brodin, L. A., additional, Theodosis, A., additional, Fousteris, E., additional, Tsiaousis, G., additional, Krommydas, A., additional, Margetis, P., additional, Katidis, Z., additional, Beldekos, D., additional, Argirakis, S., additional, Melidonis, A., additional, Foussas, S., additional, Khaleva, O., additional, Onyshchenko, O., additional, Lukaschuk, E., additional, Sherwi, N., additional, Nikitin, N., additional, Cleland, J. G. F., additional, Risum, N., additional, Jons, C., additional, Olsen, N. T., additional, Kronborg, M. B., additional, Jensen, M. T., additional, Fritz-Hansen, T., additional, Bruun, N. E., additional, Hojgaard, M. V., additional, Petrini, J., additional, Yousry, M., additional, Rickenlund, A., additional, Liska, J., additional, Franco-Cereceda, A., additional, Hamsten, A., additional, Eriksson, P., additional, Caidahl, K., additional, Eriksson, M. J., additional, Elmstedt, N., additional, Ferm-Widlund, K., additional, Westgren, M., additional, Szymczyk, E., additional, Kasprzak, J. D., additional, Wozniakowski, B., additional, Rotkiewicz, A., additional, Szymczyk, K., additional, Stefanczyk, L., additional, Michalski, B., additional, Lipiec, P., additional, Ring, L., additional, Eller, T., additional, Deegan, P., additional, Rusk, R., additional, Urbano Moral, J. A., additional, Arias, J. A., additional, Kuvin, J. T., additional, Patel, A. R., additional, Pandian, N. G., additional, Bellsham-Revell, H., additional, Bell, A. J., additional, Miller, O., additional, Greil, G. F., additional, Simpson, J., additional, Ancona, R., additional, Comenale Pinto, S., additional, Caso, P., additional, Severino, S., additional, Nunziata, L., additional, Roselli, T., additional, Dussault, C., additional, Lafitte, S., additional, Habib, G., additional, Reant, P., additional, Derumeaux, G., additional, Thibault, H., additional, Kaladaridis, A., additional, Agrios, I. A., additional, Pamboucas, C. P., additional, Mesogitis, S. M., additional, Vasiladiotis, N. V., additional, Bramos, D. B., additional, Toumanidis, S. T. T., additional, Martiniello, A. R., additional, Santangelo, G., additional, Pedrizzetti, G., additional, Tonti, G., additional, Cioppa, C., additional, Cavallaro, M., additional, Calvi, V., additional, and Chianese, R., additional

Published
2010
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26. Poster Session 2

Author

T. Andersson, A. Magnusson, I.- L. Bryngelsson, O. Frobert, K. M. Henriksson, N. Edvardsson, D. Poci, M. Polovina, T. Potpara, M. Licina, N. Mujovic, A. Kocijancic, D. Simic, M. C. Ostojic, R. A. Providencia, A. Botelho, J. Trigo, J. Nascimento, N. Quintal, P. Mota, A. M. Leitao-Marques, R. F. Bosch, W. Kirch, L. Rosin, S. N. Willich, D. Pittrow, H. Bonnemeier, M. C. Valenza, L. Martin, T. Munoz Casaubon, G. Valenza, M. Botella, M. Serrano, B. Valenza, I. Cabrera, K. Anderson, B. S. Benzaquen, N. Koziolova, J. Nikonova, Y. Shilova, D. Scherr, S. Narayan, M. Wright, D. Krummen, A. Jadidi, P. Jais, M. Haissaguerre, M. Hocini, R. Hunter, Y. Liu, Y. Lu, W. Wang, R. J. Schilling, S. Bernstein, B. Wong, R. Rooke, C. Vasquez, R. Shah, S. Rosenberg, L. Chinitz, G. Morley, M. Bashir Choudhary, F. Holmqvist, J. Carlson, H.- J. Nilsson, P. G. Platonov, A. S. Jadidi, H. Cochet, S. Miyazaki, A. J. Shah, N. Marrouche, N. Calvo, M. Nadal, D. Andreu, D. Tamborero, F. E. Diaz, A. Berruezo, J. Brugada, L. Mont, S. Fichtner, G. Hessling, H. L. Estner, C. Jilek, T. Reents, S. Ammar, J. Wu, I. Deisenhofer, H. Nakanishi, K. Kashiwase, A. Hirata, M. Wada, Y. Ueda, J. Skoda, P. Neuzil, J. Popelova, J. Petru, L. Sediva, V. Y. Reddy, L. Uldry, A. Forclaz, N. Virag, J.- M. Vesin, L. Kappenberger, R. Sehra, C. Briggs, W.- J. Rappel, M. Janotka, M. Chovanec, K. Yamashiro, K. Takami, Y. Sakamoto, K. Satoh, T. Suzuki, H. Nakagawa, A. Romanov, E. Pokushalov, S. Artemenko, V. Shabanov, I. Stenin, D. Elesin, A. Turov, A. Yakubov, M. Hioki, S. Matsuo, K. Ito, R. Narui, S. Yamashita, K. Sugimoto, M. Yoshimura, T. Yamane, L. Di Biase, J. D. Gallinghouse, K. Rajappan, J. Kautzner, A. Dello Russo, C. Tondo, F. Lorgat, A. Natale, O. Balta, K. Buenz, M. Paessler, H. Anders, M. Horlitz, T. Deneke, L. Lickfett, I. Liberman, M. Linhart, R. Andrie, E. Mittmann-Braun, F. Stockigt, G. Nickenig, J. Schrickel, R. Tilz, A. Rillig, B. Feige, A. Metzner, A. Fuernkranz, A. Burchard, E. Wissner, F. Ouyang, T. R. Betts, M. A. Jones, K. C. K. Wong, N. Qureshi, Y. Bashir, G. Corbucci, D. Losik, V. Selina, M. A. Crandall, C. Daniels, E. Daoud, S. Kalbfleisch, H. Yamaji, T. Murakami, H. Kawamura, M. Murakami, K. Hina, S. Kusachi, G. Dakos, V. Vassilikos, S. Paraskevaidis, A. Mantziari, S. Theophylogiannakos, I. Chouvarda, I. Chatzizisis, I. Styliadis, T. Kimura, K. Fukumoto, N. Nishiyama, Y. Aizawa, Y. Fukuda, T. Sato, S. Miyoshi, S. Takatsuki, A. J. Navarrete Casas, I. Ali, F. C. Conte, M. Moran, B. G. Graham, O. Kalejs, R. Lacis, P. Stradins, A. Koris, I. Putnins, M. Vikmane, A. Lejnieks, A. Erglis, A. Estrada, A. Perez Silva, S. Castrejon, D. Doiny, J. L. Merino, A. Baranchuk, I. Greiss, C. S. Simpson, H. Abdollah, D. P. Redfearn, M. Buys-Topart, R. Nitzsche, B. Thibault, S. Kathan, C. Kolb, S. Reif, S. Schade, J. Taggeselle, A. Frey, A. Birkenhagen, S. Kohler, M. Schmidt, O. Cano Perez, F. Buendia, B. Igual, J. M. Osca, J. M. Sanchez, M. J. Sancho-Tello, J. M. Olague, A. Salvador, J. M. Tolosana, J. Fernandez-Armenta, M. Matas, M. C. Barbarin, M. Habibovic, K. C. Van Den Broek, D. A. M. J. Theuns, L. Jordaens, M. Alings, P. H. Van Der Voort, S. S. Pedersen, G. Pupita, S. Molini, M. Brambatti, A. Capucci, S. Molodykh, E. M. Idov, O. V. Belyaev, L. Segreti, E. Soldati, G. Zucchelli, A. Di Cori, S. Viani, L. Paperini, R. De Lucia, M. G. Bongiorni, L. Binner, M. Taborsky, D. Bello, H. Heuer, B. Ramza, I. Jenniskens, W. B. Johnson, M. S. Silvetti, L. Rava', M. S. Russo, C. Di Mambro, A. Ammirati, G. Gimigliano, M. Prosperi, F. Drago, A. R. Santos, B. Picarra, P. Semedo, P. Dionisio, R. Matos, M. Leitao, A. Jacinto, M. Trinca, P. Mazzone, G. Ciconte, A. Marzi, G. Paglino, P. Vergara, N. Sora, S. Gulletta, P. Della Bella, P. Koppitz, A. Fach, S. Hobbiesiefken, E. Fiehn, R. Hambrecht, J. Sperzel, M. Jung, J. Schmitt, D. Pajitnev, H. Burger, G. Goebel, W. Ehrlich, T. Walther, T. Ziegelhoeffer, V. Vancura, D. Wichterle, V. Melenovsky, M. Glikson, G. Goldenberg, A. Segev, D. Dvir, J. Kuzniec, A. Finkelstein, I. Hay, V. Guetta, W. K. Choo, S. Gupta, R. Kirkfeldt, J. Johansen, E. Nohr, M. Moller, P. Arnsbo, J. Nielsen, M. Banha, P. Stojanov, S. Raspopovic, D. Vasic, D. Savic, G. Nikcevic, V. Jovanovic, P. Defaye, B. Mondesert, A. Mbaye, R. Cassagneau, V. Gagniere, J. Jacon, V. Sanfins, H. R. Reis, J. N. Nobre, V. M. Martins, L. D. Duarte, C. M. Morais, J. C. Conceicao, M. Hero, J. L. Rey, A. Ducharme, C. Simpson, C. Stuglin, L. Blier, M. Senaratne, Y. Khaykin, A. Pinter, A. Mlynarska, R. Mlynarski, M. Sosnowski, J. Wilczek, C. Iorgulescu, S. Bogdan, D. Constantinescu, C. Caldararu, M. Dorobantu, A. Radu, R.- G. Vatasescu, S. Yusu, T. Ikeda, H. Mera, Y. Miwa, A. Abe, M. Miyakoshi, T. Tsukada, H. Yoshino, V. Nayar, P. Cantelon, A. Rawling, M. R. D. Belham, P. J. Pugh, J. Osca Asensi, O. Cano, D. Tejada, B. Munoz, M. Rodriguez, J. Olague, L. Wecke, A. Van Hunnik, T. Thompson, L. Di Carlo, M. Zdeblick, A. Auricchio, F. Prinzen, A. Doltra Magarolas, B. Bijnens, E. Silva, D. Penela, M. Sitges, P. Ofman, L. Navaravong, J. Leng, A. Peralta, P. Hoffmeister, R. Levine, J. Cook, M. Stoenescu, M. E. Tettamanti, A. Revilla Orodea, J. Lopez Diaz, L. De La Fuente Galan, R. Arnold, E. Garcia Moran, J. A. San Roman Calvar, I. Gomez Salvador, K. Nakamura, M. Takami, T. Keida, A. Mesato, S. Higa, M. Shimabukuro, H. Masuzaki, R. Proietti, A. Sagone, G. Domenichini, H. Burri, C. Valzania, M. Biffi, H. Sunthorn, G. Gavaruzzi, H. Foulkes, G. Boriani, S. Koh, W. Hou, J. Snell, J. Poore, N. Dalal, G. Bornzin, A. Kloppe, D. Mijic, H. Bogossian, I. Ninios, M. Zarse, B. Lemke, L. Guedon-Moreau, C. Kouakam, D. Klug, C. Marquie, F. Ziglio, S. Kacet, H. Mohamed Fereig Hamed, A. M. A. L. Hamdy, A. H. M. E. D. Abd El Aziz, M. R. V. A. T. Nabih, R. E. H. A. B. Hamdy, A. Yaminisaharif, G. H. Davoudi, A. Kasemisaeid, S. Sadeghian, A. Vasheghani Farahani, P. Yazdanifard, A. Shafiee, C. Alonso, C. Grimard, G. Jauvert, A. Lazarus, L. L. Mont, J. Ortiz-Perez, T. Caralt, J. Escudero, F. Perez, K. M. Griffith, R. Ferreyra, P. Urena, M. Demas, C. Muratore, H. Mazzetti, J. Guardado, M. Fernandes, V. H. Pereira, F. Canario-Almeida, F. Ferreira, B. Rodrigues, J. Almeida, A. Sokal, E. Jedrzejczyk, R. Lenarczyk, S. Pluta, O. Kowalski, P. Pruszkowska, A. Swiatkowski, Z. Kalarus, M. Heinke, B. Ismer, H. Kuehnert, T. Heinke, R. Surber, N. Osypka, D. Prochnau, H. R. Figulla, S. Iacopino, M. Landolina, A. Proclemer, L. Padeletti, V. Calvi, A. Pierantozzi, P. Di Stefano, A. Bauer, F. Bode, F. Le Gal, J. C. Deharo, M. Delay, J. Clementy, M. Kawamura, Y. Munetsugu, K. Tanno, Y. Kobayashi, D. Cannom, J. Hosoda, T. Ishikawa, K. Andoh, M. Nobuyoshi, S. Fujii, S. Shizuta, T. Isshiki, M. A. Castel, F. Perez-Villa, B. Vidal, P. Pruszkowska-Skrzep, M. Szulik, T. Kukulski, L. Gianfranchi, K. Bettiol, F. Pacchioni, P. Alboni, R. Abu Sham'a, J. Buber, E. Nof, R. Kuperstein, M. Feinberg, D. Luria, M. Eldar, K. Parks, J. R. Stone, J. P. Singh, E. Hatzinikolaou-Kotsakou, M. Kotsakou, T. H. Beleveslis, G. Moschos, E. Reppas, P. Latsios, K. Tsakiridis, A. Kazemisaeid, G. Davoodi, A. Yamini Sharif, M. Sheikhvatan, M. Toniolo, G. Zanotto, A. Rossi, L. Tomasi, C. Vassanelli, H. Versteeg, P. M. C. Mommersteeg, G. Vergara, J. Blauer, R. Ranjan, S. Vijayakumar, E. Kholmovski, N. Volland, R. Macleod, L. E. Aguinaga Arrascue, A. Bravo, P. Garcia Freire, P. Gallardo, E. Hasbani, J. Dantur, R. Quintana, P. P. Adragao, D. Cavaco, L. Parreira, K. Reis Santos, P. Carmo, R. Miranda, S. Marcelino, D. Cabrita, P. Sommer, T. Gaspar, S. Rolf, A. Arya, C. Piorkowski, G. Hindricks, E. Valles Gras, V. Bazan, L. Portillo, F. Suarez, J. Bruguera, J. Marti, Y. Huo, S. Richter, R. Schoenbauer, N. Rivas, J. Casaldaliga, I. Roca, L. Dos, J. Perez-Rodon, A. Pijuan, D. Garcia-Dorado, A. Moya, H. B. Carter, A. Garg, J. Hegrenes, H. J. Sih, L. R. Teplitsky, K. Kuroki, H. Tada, Y. Seo, T. Ishizu, M. Igawa, Y. Sekiguchi, K. Kuga, K. Aonuma, C. Rodriguez A, J. Mejias, P. Hidalgo, J. A. Hidalgo L, M. Orczykowski, P. Derejko, F. Walczak, E. Szufladowicz, P. Urbanek, R. Bodalski, K. Bieganowska, L. Szumowski, P. Peichl, R. Cihak, I. Skalsky, P. Kubus, P. Vit, L. Zaoral, R. A. Gebauer, M. Fiala, J. Janousek, K. Hiroshima, M. Goya, M. Ohe, K. Hayashi, Y. Makihara, M. Nagashima, Y. An, M. Schloesser, T. Lawrenz, D. Meyer Zu Vilsendorf, C. Strunk-Mueller, C. Stellbrink, J. Papagiannis, D. Avramidis, C. Kokkinakis, G. Kirvassilis, G. Eidelman, A. Arenal, T. Datino, F. Atienza, E. Gonzalez Torrecilla, A. Miracle, J. Hernandez, F. Fernandez Aviles, E. Ene, P. Insulander, H. Bastani, F. Braunschweig, N. Drca, G. Kenneback, J. Schwieler, J. Tapanainen, M. Jensen-Urstad, B. Andrea, E. M. A. Andrea, W. M. Maciel, L. S. Siqueira, R. C. Cosenza, F. M. Mittidieri, S. F. Farah, J. A. Atie, E. Kanoupakis, E. Kallergis, H. Mavrakis, C. Goudis, I. Saloustros, N. Malliaraki, G. Chlouverakis, P. Vardas, J. L. Bonnes, J. Jaspers Focks, S. W. Westra, M. A. Brouwer, J. L. R. M. Smeets, G. Inama, C. Pedrinazzi, F. Oliva, M. Senni, M. Zoni Berisso, S. Mostov, M. Haim, R. Nevzorov, D. Hasadi, B. Starsberg, A. Porter, J. Kuschyk, A. Schoene, F. Streitner, C. G. Veltmann, R. Schimpf, M. Borggrefe, U. Luesebrink, A. Gardiwal, H. Oswald, T. Koenig, D. Duncker, G. Klein, R. Bastiaenen, V. Batchvarov, O. Atty, J. H. Cheng, E. R. Behr, M. M. Gallagher, A. H. Starrenburg, K. Kraaier, M. F. Scholten, J. Van Der Palen, S. Adhya, L. A. Smith, T. Zhao, C. Bannister, R. H. Kamdar, M. Martinelli, S. Siqueira, R. Greco, S. A. D. Nishioka, A. A. A. Pedrosa, R. Alkmim-Teixeira, G. L. Peixoto, R. Costa, J. C. Nielsen, P. T. Mortensen, J. B. Johansen, W. Kwasniewski, A. Filipecki, D. Urbanczyk-Swic, W. Orszulak, M. Trusz - Gluza, J. Jimenez-Candil, J. Morinigo, C. Ledesma, C. Martin-Luengo, T. Vogtmann, M. Gomer, S. Stiller, V. Kuehlkamp, G. Zach, S. Loescher, S. Kespohl, G. Baumann, J. D. Snell, N. Korsun, J. R. Snell, B. Morley, R. Bharmi, Y. Nabutovsky, M. Mollerus, L. Naslund, A. Meyer, M. Lipinski, B. Libey, K. Dornfeld, A. Martin, M. Gallego, M. K. De Bie, J. B. Van Rees, C. J. Borleffs, J. Thijssen, J. W. Jukema, M. J. Schalij, L. Van Erven, E. T. Van Der Velde, T. A. Witteman, H. Foeken, T. Szili-Torok, F. Akca, K. Caliskan, F. Ten Cate, M. Michels, D. C. Cozma, L. Petrescu, C. Mornos, S. I. Dragulescu, J. A. Groeneweg, B. K. Velthuis, M. G. P. J. Cox, P. Loh, D. Dooijes, M. J. Cramer, J. M. T. De Bakker, R. N. W. Hauer, S. D. Park, S. H. Shin, S. I. Woo, J. Kwan, K. S. Park, D. H. Kim, A. Iorio, L. Vitali Serdoz, F. Brun, E. Daleffe, M. Zecchin, M. Dal Ferro, S. Santangelo, G. F. Sinagra, S. Ouali, R. Hammemi, S. Hammas, S. Kacem, R. Gribaa, E. Neffeti, F. Remedi, E. Boughzela, P. Korantzopoulos, K. Letsas, Z. Christogiannis, K. Kalantzi, A. Ntorkos, J. Goudevenos, P. W. X. Foley, L. Yung, E. Barnes, M. Kikuchi, H. Ito, F. Miyoshi, R. Pecini, J. M. Marott, G. B. Jensen, J. Theilade, T. Mine, T. Kodani, T. Masuyama, I. M. Mozos, C. Serban, C. Costea, L. Susan, P. Barthel, A. Mueller, M. Malik, G. Schmidt, O. Karakurt, H. Kilic, D. R. Munevver Sari, D. Mroczek-Czernecka, A. Z. Pietrucha, A. Borowiec, M. Wnuk, I. Bzukala, O. Kruszelnicka, E. Konduracka, J. Nessler, Y. Kikuchi, A. Meireles, C. Gomes, D. Anjo, C. Roque, A. Pinheiro Vieira, V. Lagarto, A. Hipolito Reis, S. Torres, L. Miller, G. Vedrenne, E. Bruguiere, A. Redheuil, T. Lavergne, J. Y. Le Heuzey, E. Mousseaux, A. Hersi, K. Alhabib, H. Alfaleh, K. Sulaiman, W. Almahmeed, J. Alsuwidi, H. Amin, A. Almotarreb, H. W. K. Pang, K. Michael, E. J. Pereira, P. W. Munt, M. F. Fitzpatrick, A. S. Revishvili, G. Simonyan, T. Dzhordzhikiya, O. Sopov, V. Kalinin, E. T. Locati, A. M. Vecchi, G. Cattafi, A. Sachero, M. Lunati, S. Sayah, A. Alizadeh, N. Nazari, M. Hekmat, M. Moradi, M. Zeighami, H. Ghanji, K. Suzuki, M. Takagi, K. Maeda, H. Tatsumi, P. Vieira, H. Reis, A. Toth, H. Vago, P. Takacs, E. Edes, A. Marki, G. Y. Balazs, K. Huttl, B. Merkely, F. Lainis, M. M. Buckley, E. J. Johns, C. M. Seifer, L. Daba, K. Liebrecht, W. Piwowarska, J. Toquero Ramos, E. Perez Pereira, C. Mitroi, V. Castro Urda, J. M. Fernandez Villanueva, A. Corona Figueroa, L. Hernandez Reina, I. Fernandez Lozano, A. Bartoletti, P. Bocconcelli, S. Giuli, R. Massa, C. Svetlich, G. Tarsi, F. Tronconi, E. Vitale, P. Stryjewski, M. Wegrzynowska, A. Lousinha, J. Labandeiro, E. Antunes, S. Silva, S. Alves, A. Timoteo, M. Oliveira, R. Cruz Ferreira, and J. Jedrzejczyk-Spaho

Subjects
medicine.medical_specialty, Voltage-dependent calcium channel, business.industry, medicine.drug_class, Umbilical artery, 030204 cardiovascular system & hematology, Cyclase, 3. Good health, Low testosterone levels, 03 medical and health sciences, 0302 clinical medicine, Bkca channel, Endocrinology, Physiology (medical), Internal medicine, medicine.artery, Natriuretic peptide, Medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Ionic Channels
Abstract

Inthelastdecadesseveralinvestigatorshavesuggestedtheassociationofandrogenswithhypertension. Recently, some studies have shown that the incidence of cardiovascular diseases is increased in men with low testosterone levels, suggesting a protective role of androgens. Hypertension is one of the mostcommonproblemsinpregnancythatcomplicates5-10 %ofpregnancies.Anincreaseofmorbidity wasobservedinbabiesfrompregnantwomenwithhypertension.However,thepathogenesisremains unclearandthislimitstheabilitytopreventandtreatthispathology.Thebeneficialeffectsofandrogens for vascular system are associated with their ability to cause vasorelaxation. Inhuman vessels, this non genomiceffectofandrogensappeartobeduetoactivationoflargeconductancecalcium-activatedpotassiumchannels(BKCa)andvoltagegatedpotassiumchannels(KV)whichisinducedbycGMPincrease andaconsequentactivationofcGMP-dependentproteinkinase(PKG).Ontheotherhand,thegenomic effects of androgens concerning ionic channels are almost unknown. Our previous studies suggested that androgens increase the expression of BKCa channels and decrease expression of L-type calcium channels (LTCC). The aim of this work was to analyze the genomic effects of androgens on theexpressionofotherproteinsinvolvedintheregulationofvascularcontractility,suchassolubleguanylate cyclase (sGC), the natriuretic peptide receptor-A (NPRA) and PKG. This study also aimed to compare the expression levels of these proteins in human umbilical artery (HUA) from normotensive andhypertensivepregnantwomen.ToachievethesegoalsrealtimePCRwasperformedusingsmooth

Published
2011
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