1. Respiratory Syncytial Virus-Associated Hospital Admissions in Children Younger Than 5 Years in 7 European Countries Using Routinely Collected Datasets
- Author
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Reeves, Rachel M, van Wijhe, Maarten, Tong, Sabine, Lehtonen, Toni, Stona, Luca, Teirlinck, Anne C, Fernandez, Liliana Vazquez, Li, You, Giaquinto, Carlo, Fischer, Thea Kølsen, Demont, Clarisse, Heikkinen, Terho, Speltra, Irene, van Boven, Michiel, Bøås, Håkon, Campbell, Harry, Nair, Harish, Simonsen, Lone, Trebbien, Ramona, Bangert, Mathieu, Teirlinck, Anne, van der Hoek, Wim, van der Maas, Nicoline, Meijer, Adam, Bøas, Håkon, Bekkevold, Terese, Flem, Elmira, Cheret, Arnaud, Leach, Amanda, Stoszek, Sonia, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Openshaw, Peter, Abram, Michael, Swanson, Kena, Rosen, Brian, and Molero, Eva
- Subjects
Male ,0301 basic medicine ,medicine.medical_specialty ,Pediatrics ,hospital admissions ,respiratory syncytial virus ,030106 microbiology ,Respiratory Syncytial Virus Infections ,Europe ,RSV ,national registry data ,Virus ,03 medical and health sciences ,0302 clinical medicine ,Epidemiology ,Humans ,Immunology and Allergy ,Medicine ,030212 general & internal medicine ,Respiratory system ,Respiratory Tract Infections ,business.industry ,Time trends ,Vaccination ,Infant, Newborn ,Infant ,Hospitals ,3. Good health ,Pathogenic organism ,Hospitalization ,Infectious Diseases ,medicine.anatomical_structure ,Immunization ,Child, Preschool ,Respiratory Syncytial Virus, Human ,Hospital admission ,Female ,business ,Respiratory tract - Abstract
Background Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection (RTI) in young children. Registries provide opportunities to explore RSV epidemiology and burden. Methods We explored routinely collected hospital data on RSV in children aged < 5 years in 7 European countries. We compare RSV-associated admission rates, age, seasonality, and time trends between countries. Results We found similar age distributions of RSV-associated hospital admissions in each country, with the highest burden in children Conclusions Our results demonstrate the benefits and limitations of using linked routinely collected data to explore epidemiology and burden of RSV. Our future work will use these data to generate estimates of RSV burden using time-series modelling methodology, to inform policymaking and regulatory decisions regarding RSV immunization strategy and monitor the impact of future vaccines.
- Published
- 2020
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