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Comments on the interpretation of analytical findings on urine samples generated by the laboratory by the forensic toxicologist. Role of the identified substances in the cause of death; Assessment of toxicity or impairment in living individuals; Correlation of impairment with drug concentrations.

The article presents the postmortem case studies to determine the distribution of methylone. It mentions about a 19-year old male who was died due to cardiac arrest. It also mentions about a 21-year old female who died due to drowning while chasing by the police and a 35-year old female who was found dead on her bed with a cutting wound on neck and gunshot wound at the back of her head. The studies suggest that methylone and Methylenedioxypyrovalerone are more toxic when taken together.

Investigates hydroxycarbazepine distribution in three postmortem cases by researchers from Baltimore, Maryland. Detection of the active metabolite of the anticonvulsant oxacarbazepine in the biological specimens submitted for toxicological analysis; Use of gas chromatography-nitrogen-phosphorus for the detection of the compound; Assertion from the medical examiner that the hydroxycarbazepine was an incidental finding to the cause of death.

Presents an analysis of metformin in antemortem serum and postmortem specimens by a novel high-performance liquid chromatography (HPLC) method and application to an intoxication case. Performance characteristics of the metformin assay; Drugs tested and found not to interfere with the metformin assay; Elimination half-life of metformin.

Reports on a case in which xylazine was identified in a suicide by hanging. Confirmation of the presence of xylazine by full scan electron ionization gas chromatography-mass spectrometry; Pharmacological analysis of the suicide case; Number of published cases of xylazine's involvement in human drug-related deaths and impairment.

Cites findings of a toxicological testing conducted on sedative-analgesic xylazine which is used in veterinary medicine after cases of xylazine's involvement in human drug-related deaths and impairment were observed. Medical history of the 42-year-old man who died after taking the medication; Details of methodology adopted by researchers to detect xylazine in blood of the patient; Revelation that full scan electron ionization gas chromatography-mass spectrometry confirmed presence of xylazine in the patient.