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Your search keyword '"Golby, Alexandra J."' showing total 13 results
Start Over Author "Golby, Alexandra J." Publisher oxford university press / usa
13 results on '"Golby, Alexandra J."'

5. Right inferior longitudinal fasciculus lesions disrupt visual-emotional integration.

Author

Fischer, David B., Perez, David L., Prasad, Sashank, Rigolo, Laura, O'Donnell, Lauren, Acar, Diler, Meadows, Mary-Ellen, Baslet, Gaston, Boes, Aaron D., Golby, Alexandra J., and Dworetzky, Barbara A.

Subjects
TEMPORAL lobe, BRAIN physiology, TISSUE wounds, EMOTIONS, VISUAL perception, MENTAL illness, TUMORS
Abstract

The mechanism by which the brain integrates visual and emotional information remains incompletely understood, and can be studied through focal lesions that selectively disrupt this process. To date, three reported cases of visual hypoemotionality, a vision-specific form of derealization, have resulted from lesions of the temporo-occipital junction. We present a fourth case of this rare phenomenon, and investigate the role of the inferior longitudinal fasciculus (ILF) in the underlying pathophysiology. A 50-year-old right-handed male was found to have a right medial temporal lobe tumor following new-onset seizures. Interstitial laser ablation of the lesion was complicated by a right temporo-parieto-occipital intraparenchymal hemorrhage. The patient subsequently experienced emotional estrangement from visual stimuli. A lesion overlap analysis was conducted to assess involvement of the ILF by this patient's lesion and those of the three previously described cases, and diffusion tensor imaging was acquired in our case to further investigate ILF disruption. All four lesions specifically overlapped with the expected trajectory of the right ILF, and diminished structural integrity of the right ILF was observed in our case. These findings implicate the ILF in visual hypoemotionality, suggesting that the ILF is critical for integrating visual information with its emotional content. [ABSTRACT FROM AUTHOR]

Published
2016
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6. Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma.

Author

Aizer, Ayal A., Arvold, Nils D., Catalano, Paul, Claus, Elizabeth B., Golby, Alexandra J., Johnson, Mark D., Al-Mefty, Ossama, Wen, Patrick Y., Reardon, David A., Lee, Eudocia Q., Nayak, Lakshmi, Rinne, Mikael L., Beroukhim, Rameen, Weiss, Stephanie E., Ramkissoon, Shakti H., Abedalthagafi, Malak, Santagata, Sandro, Dunn, Ian F., and Alexander, Brian M.

Published
2014
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