1. Omicron Infections in Vaccinated Pediatric Solid Organ Transplant Recipients.
- Author
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McAteer, John, Kalluri, Divya D, Abedon, Rivka R, Qin, Caroline X, Auerbach, Scott R, Charnaya, Olga, Danziger-Isakov, Lara A, Ebel, Noelle H, Feldman, Amy G, Hsu, Evelyn K, Mohammad, Saeed, Perito, Emily R, Thomas, Ashley M, Chiang, Teresa P Y, Garonzik-Wang, Jacqueline M, Segev, Dorry L, Werbel, William A, and Mogul, Douglas B
- Subjects
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BREAKTHROUGH infections , *COVID-19 , *IMMUNIZATION , *IMMUNOGLOBULINS , *COVID-19 vaccines , *CORONAVIRUS spike protein , *PATIENTS , *FISHER exact test , *RISK assessment , *SEVERITY of illness index , *SURVEYS , *DISEASE prevalence , *IMMUNOENZYME technique , *DESCRIPTIVE statistics , *SOCIODEMOGRAPHIC factors , *DATA analysis software , *TRANSPLANTATION of organs, tissues, etc. , *DISEASE risk factors , *SYMPTOMS , *CHILDREN - Abstract
SARS-CoV-2 infection during the Omicron period was frequent amongst a cohort of vaccinated pediatric solid organ transplant recipients (pSOTRs) despite robust anti-receptor-binding domain (anti-RBD) antibody response, suggesting poor neutralizing capacity against Omicron subvariants. Breakthrough infections among pSOTRs were overall limited in severity. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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