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Granulomatosis with polyangiitis (GPA) is a rare multisystem autoimmune disease of unknown aetiology with only a few reported cases about spinal cord involvement in the literature. We report on the case of an established GPA presented with acute onset bilateral lower limb weakness, urinary retention and faecal incontinence consistent with transverse myelitis. Contrast-enhanced MRI scanning revealed T2 hyperintensity extending from the T1 to conus medularis, without any gadolinium enhancement features suggestive of long segment myelitis. He was successfully treated with I.V IG followed by Rituximab. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 34-year-old male with acute-onset breathlessness and headache, and a blood pressure of 220/120 in both upper limbs. Examinations showed the presence of right renal artery stenosis and extensive calcification in the descending thoracic aorta and upper abdominal aorta, which were consistent with a diagnosis of Takayasu disease, angiographic type III. The patient was started on steroids, MMF and an antihypertensive.