1. TRTools: a toolkit for genome-wide analysis of tandem repeats.
- Author
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Mousavi, Nima, Margoliash, Jonathan, Pusarla, Neha, Saini, Shubham, Yanicky, Richard, and Gymrek, Melissa
- Subjects
- *
TANDEM repeats , *QUALITY control , *PYTHON programming language , *GENE libraries - Abstract
Summary A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotypers. Availability and implementation TRTools is freely available at https://github.com/gymreklab/TRTools. Detailed documentation is available at https://trtools.readthedocs.io. Supplementary information Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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