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Background: Diabetic peripheral neuropathy (DPN) is a common complication estimated to affect 30-50% of individuals with diabetes. It is the most frequent and annoying complication of diabetes mellitus (DM), leading to the greatest morbidity and mortality and giving rise to a huge economic trouble for diabetes care, 2-3%develop a foot ulcer annually. Objective: The aim of the present study is to evaluate the relationship between Glycated albumin and peripheral diabetic neuropathy. Method: The present study was conducted on 40 patients with diabetes mellitus, who were collected from outpatient clinic in Ain Shams University Hospitals and national institute of diabetes and endocrinology (NIDE), from May to September 2017. Results: It found that demyelinted type of diabetic neuropathy (n=5) significantly had highest FBG (P=0.031), 2PPBG (P=0.039) and glycated albumin (P=0.033) and no significant HbA1c (P=0.199) however in axonal and mixed types of diabetic neuropathy showed no significant different regards FBG, 2PPBG, HbA1c and glycated albumin (P>0.05). Conclusion: glycated albumin has relationship with peripheral diabetic neuropathy. Also, Glycated albumin ≥ 12.5 (gm/dL) had perfect diagnostic characteristics in diabetic neuropathy. [ABSTRACT FROM AUTHOR]