1. CARD9 mutation linked to Corynespora cassiicola infection in a Chinese patient.
- Author
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Yan, X.X., Yu, C.P., Fu, X.A., Bao, F.F., Du, D.H., Wang, C., Wang, N., Wang, S.F., Shi, Z.X., Zhou, G.Z., Tian, H.Q., Liu, H., and Zhang, F.R.
- Subjects
MYCOSES ,CORYNESPORA ,SKIN diseases ,GENETIC mutation ,NUCLEOTIDE sequence ,GENETICS - Abstract
Corynespora cassiicola is a plant pathogen associated with leaf-spotting disease. The fungus has been found on diverse substrates: leaves, stems and roots of plants; nematode cysts and human skin. It rarely causes human infections. Here we report one case of subcutaneous phaeohyphomycosis caused by C. cassiicola with prominent tissue necrosis in a woman. All of her clinical features pointed towards a genetic linkage. Hence, whole-exome sequencing and Sanger sequencing were performed on this patient. One mutation of CARD9 was detected. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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