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Your search keyword '"Sun, Ruitong"' showing total 1 results
Start Over Author "Sun, Ruitong" Publisher oxford university press / usa
1 results on '"Sun, Ruitong"'

1. Evaluation of quercetin as a potential cytoprotector against acetaldehyde using the cultured hepatocyte model with aldehyde dehydrogenase isozyme deficiency.

Author

Xu, Yuhang, Sawamoto, Takeshi, Sun, Ruitong, Ishikura, Aki, Munemasa, Shintaro, Murata, Yoshiyuki, Satoh, Ayano, Matsumoto, Akiko, Nakamura, Toshiyuki, and Nakamura, Yoshimasa

Subjects
ALDEHYDE dehydrogenase, CYTOPROTECTION, QUERCETIN
Abstract

Protective effect of quercetin against acetaldehyde was evaluated using the cultured hepatocyte models with aldehyde dehydrogenase (ALDH) isozyme deficiency (aldh2-kd and aldh1a1-kd). The quercetin-induced cytoprotection against acetaldehyde in the ALDH1A1-deficient mutant (aldh1a1-kd) was weaker than that in the wild type. Furthermore, quercetin did not enhance the ALDH activity in aldh1a1-kd cells, suggesting that ALDH1A1 is involved in quercetin-induced cytoprotection. [ABSTRACT FROM AUTHOR]

Published
2024
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